MAY 6, :30 AM 3:30 PM

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1 FRIDAY, MAY 6, :30 AM 3:30 PM Smilow Center for Translational Research 3400 Civic Center Blvd Philadelphia, PA Penn Pituitary Center PRESENTS 2016 PITUITARY UPDATE A CME/CNE-Certified Course REGISTER ONLINE AT PennMedicine.org/CME/PITUITARY

2 Penn Medicine s Abramson Cancer Center PRESENTS 2016 PITUITARY UPDATE FRIDAY, MAY :30 AM 3:30 PM ARTHUR RUBENSTEIN AUDITORIUM SMILOW TRANSLATIONAL RESEARCH CENTER The Arthur Rubenstein Auditorium is located on the first floor of the Smilow Translational Research Center, which is adjacent to the Perelman Center for Advanced Medicine. Enter through the Perelman Center. For public transportation, directions, and parking information, go to PennMedicine.org/ Perelman/visitor_info Perelman Center is conveniently reached by several public transportation routes. Amtrak, 30th Street Station Septa Regional Rail (University City Station) LUCY - Loop Through University City NJ PATCO Trains Parking is available at the Perelman Center parking garage. Most of the conference materials will be available online. Please bring your electronic device to view presentations in real time. OVERVIEW This course will present the newest approaches and techniques in the diagnosis and treatment of pituitary disease, including acromegaly and Cushing s syndrome. Diagnosis and treatment will be covered from the interdisciplinary perspective of endocrinology, radiology, neuro-opthamology, neurosurgery, and radiation oncology. The approach will be both didactic and interactive, and include lectures, case conferences, panel discussions and meet-the experts at lunch. LEARNING OBJECTIVES At the completion of this course, participants should be able to: Evaluate a sellar mass to determine if it is a pituitary adenoma or other lesion Discuss the value and limits of MRI in evaluating a sellar mass Explain the potential and limits of endoscopic transsphenoidal surgery for pituitary adenoma Describe the different types of radiation, including linear accelerator (IMRT, Cyberknife), gamma radiation, (Gamma Knife) and proton beam Treat, medically, patients who have acromegaly and Cushing s disease. WHO SHOULD ATTEND The target audience is endocrinologists, neurosurgeons, ophthalmologists, general radiologists, nurse practitioners, residents and fellows.

3 AGENDA 7:30 am Continental Breakfast 8:20 am Welcome DIAGNOSIS 8:30 am Differential Diagnosis of a Sellar Mass Hormonal 8:50 am Differential Diagnosis of a Sellar Mass Radiologic Laurie A. Loevner, MD 9:10 am Differential Diagnosis of Cushing s Syndrome Julia N. Kharlip, MD 9:40 am Diagnostically Challenging Pituitary Cases Moderator: Panel: All speakers above 10:25 am Coffee Break TREATMENT 10:40 am Endonasal Surgery for Pituitary Adenomas M. Sean Grady, MD 11:00 am Extended Endonasal Surgery and Other New Surgical Techniques for Sellar Masses John Y.K. Lee, MD 11:20 am Salt and Water Abnormalities after Pituitary Surgery Julia N. Kharlip, MD 11:40 am Radiation for Residual Adenomas: Proton Beam, Gamma Knife, Cyberknife, IMRT Robert A. Lustig, MD 12:00 pm Lunch with the Experts. Topics to include medical, nursing, ophthalmologic, radiation, radiologic, and surgical issues in pituitary disease. Michelle Alonso-Basanta, MD, PhD Craig A. Alter, MD Jayme Ewanichak, CRNP M. Sean Grady, MD Julia N. Kharlip, MD John Y. Lee, MD Laurie A. Loevner, MD Robert A. Lustig, MD Caitlin Reynolds, RN 1:20 pm Managing Growth Hormone Treatment in the Pediatric-Adult Transition Craig A. Alter, MD 1:40 pm Treatment of Cushing s Disease 2:10 pm Challenges in the Management of Pituitary Disease Moderator: Panel: M. Sean Grady, MD Julia N. Kharlip, MD John Y. Lee, MD Robert A. Lustig, MD 3:20 pm Conclusion 3:30 pm Evaluation and Adjourn

4 REGISTRATION Non- Penn Physicians...$ Non- Penn residents, fellows, nurses, and other healthcare professionals...$75.00 Faculty, staff, residents, fellows and/or students of the University of Pennsylvania...$25.00 Registration fee includes breakfast, lunch and course syllabus. Parking fees are not covered. For additional information please contact Barbara Lopez at REGISTER ONLINE AT PennMedicine.org/CME/Pituitary ACCREDITATION AND DESIGNATION OF CREDIT ACCREDITATION The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The Hospital of the University of Pennsylvania, Department of Nursing Education, Innovation and Professional Development is an approved provider of continuing nursing education by the PA State Nurses Association, an accredited approver by the American Nurses Credentialing Center s Commission on Accreditation. DESIGNATION OF CREDIT PHYSICIANS: The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 6.75 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. NURSES: This activity has been approved for 6.75 contact hours. AAPA: AAPA accepts certificates of participation for educational activities certified for Category 1 credit from AOACCME, Prescribed credit from AAFP, and AMA PRA Category 1 Credits. DISCLOSURES The Perelman School of Medicine at the University of Pennsylvania, Office of Continuing Medical Education, adheres to the ACCME Standards for Commercial Support. Faculty disclosure information will be made available in the conference materials and syllabus. Faculty members are also expected to disclose to participants any discussion of off-label and / or investigational use of pharmaceutical products or devices with in their presentations. CANCELLATION POLICY The University reserves the right to cancel or postpone any course due to unforeseen circumstances. In the event of cancellation or postponement, the University will notify all pre-registrants but is not responsible for any related costs or expenses to participants, including cancellation fees assessed by hotels, airlines and travel agencies. In order to process refunds for conference withdrawals, we must receive cancellation in writing by April 15, SERVICES FOR THE DISABLED If special arrangements are required for an individual with a disability to attend this meeting, please contact Barbara Lopez at , no later than April 28, 2016 NONDISCRIMINATION STATEMENT The University of Pennsylvania values diversity and seeks talented students, faculty and staff from diverse backgrounds. The University of Pennsylvania does not discriminate on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status or any other legally protected class status in the administration of its admissions, financial aid, educational or athletic programs, or other University administered programs or in its employment practices. Questions or complaints regarding this policy should be directed to the Executive Director of the Office of Affirmative Action and Equal Opportunity Programs, Sansom Place East, 3600 Chestnut Street, Suite 228, Philadelphia, PA ;or (Voice).

5 SPEAKERS COURSE CO-DIRECTORS Professor, Medicine Medical Director, Penn Pituitary Center M. Sean Grady, MD Charles Harrison Frazier Professor, Neurosurgery Neurosurgeon-in-Chief, Hospital of the University of Pennsylvania Julia Kharlip, MD Academic Clinical Assistant Professor, Medicine Associate Medical Director, Penn Pituitary Center PENN MEDICINE FACULTY Michelle Alonso-Basanta, MD, PhD Helene Blum Assistant Professor, Radiation Oncology Craig A. Alter, MD Academic Clinical Professor, Pediatric Medicine Children s Hospital of Philadelphia Jayme Ewanichak, CRNP Nurse Practioner, Penn Pituitary Center John Y.K. Lee, MD Assistant Professor of Neurosurgery Medical Director, Penn Gamma Knife Laurie Loevner, MD Professor of Radiology Director, Head and Neck Imaging Robert Lustig, MD Professor, Clinical Radiation Oncology Caitlin Reynolds, RN Nurse, Penn Pituitary Center

6 Abramson Cancer Center 3600 Market Street Suite 210 Philadelphia, PA Penn Pituitary Center PRESENTS 2016 PITUITARY UPDATE A CME/CEU-Certified Course MAY 6, :30 AM 3:30 PM PRESORTED Non-Profit Org. U.S. Postage PAID Permit No Phila, PA 19176