BSN. NUR 4314 Genetics and Genomics Summer 2017
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1 ANGELO STATE UNIVERSITY BSN NUR 4314 Genetics and Genomics Summer 2017 ANGELO STATE UNIVERSITY Department of Nursing Jacqueline Brown, M.S., PhD, RN
2 Course Title: Genetics and Genomics Course Number: NUR 4314 Prerequisite: Pathophysiology NUR 2324 Credits: Three semester credit hours (3-0-0) Online class: Meets completely online using Blackboard Pre-requisite Skills Assessing internet web sites, use of ASU Library resources, and proficiency with Microsoft Word and /or PowerPoint are an expectation of on-line course delivery. Tutorials for ASU Library and for Blackboard are available through RamPort. The ASU Undergraduate Nursing Handbook must be reviewed before taking this course: Course Delivery This is an online course offering. Browser Compatibility Check It is the student s responsibility to ensure that the browser used to access course material on his/her computer is compatible with ASU s Blackboard Learning System. Faculty reserves the right to deny additional access to course assignments lost due to compatibility issues. Students are responsible for reviewing the guidelines poste din this course regarding accessing Blackboard assignments. Problems in this area need to be discussed with faculty at the time of occurrence, either via a phone call (preferred) during posted acceptable hours for calling, or via notification during times outside those posted for calls. Be sure to perform a browser test. Select the Support tab from the Blackboard homepage ( Select Test your Browser option. Faculty Jacqueline Brown, MS, PhD, RN Office: VIN 276 Phone: Fax: Jacqueline.brown@angelo.edu(preferred method of communication) General Information Lecture days/times: Monday through Thursday 8-10:30
3 Office hours Monday through Thursday 10:30-11:30 Course Description: This course provides students with a sound knowledge of genetics and genomics essential for health care providers in evaluating needs of patients and delivering of care to patients and families. The course prepares nursing students by reinforcing the basic principles of genetics while exploring new advances and discussing how these advances will affect health The course focuses on the relationships of genetics and genomics to health, prevention, screening, diagnostics, prognostics, selection of treatment, and monitoring of treatment effectiveness. Genomic influences on complex health problems, chromosomal and mitochondrial diseases, enzyme and collagen disorders, childhood onset disorders, adult onset disorders, psychiatric and behavioral disorders and cancer will be covered. Student Learning Outcomes By completing all course requirements, students will be able to : 1. Understand and integrate basic aspects of genetics and genomics to plan, coordinate patient centered care 2. To integrate information regarding the social, ethical and legal implications of genetics and genomics with the role of a nurse as educator and patient advocate Assessment (s) or activity (ies) validating outcome achievement: Web search reluctance genetic testing/summary Article/review/when to tell and test for genetic carrier status Care plan development Educational plan development Explore pros and cons of sharing information regarding inheritable genes/unintended consequences for sharing this information Article/ethics, evidence and cost in newborn screening Explore the differences between life insurance, disability insurance and long term insurance and the ethical implications of the omission of these types of insurance from GINA Mapping to BSN Program Outcomes/Essentials Essential 7. Implement health promotion and disease prevention strategies to provide culturally competent Essential 7. Implement health promotion and disease prevention strategies to provide culturally competent Essential 8. Demonstrate standards of professional, ethical and legal conduct
4 3. Understand policy implications of genomic health care, newborn screening and prenatal genetics to guide nursing practice 4. Apply concepts of obtaining family history (pedigree) and assessment of risk Using a reputable, patient oriented website for congenital anomaly, provide an outline of the information that would help you build a good plan of care to guide the parents of a newly diagnosed infant. What are pros and cons of direct to consumer Testing? Family history exercise/ create a 3 generational pedigree. Build preventive plan of care for any condition for which there is potential risk. Essential 3. Identify and appraise best research evidence to improve and promote quality patient outcomes. Essential 4. Utilize technology to access information, evaluate patient data, and document Essential 7. Implement health promotion and disease prevention strategies to provide culturally competent Essential 8. Demonstrate standards of professional, ethical and legal conduct Essential 1. Integrate nursing and related theories into the delivery of safe nursing care to diverse populations. Essential 7. Implement health promotion and disease prevention strategies to provide culturally competent
5 5. Identify and integrate information of genomic science for the management of cancer prevention and treatment Explore internet for risk assessment tools for various types of cancers. Essential 1. Integrate nursing and related theories into the delivery of safe nursing care to diverse populations. Essential 3. Identify and appraise best research evidence to improve and promote quality patient outcomes. Essential 4. Utilize technology to access information, evaluate patient data, and document 6. Evaluate and apply information regarding health promotion, diagnosis, prevention, and treatment of complex health problems that have significant public health importance 7. Understand the contribution of genetics and genomics Clinical trials.gov activity/discuss trial purpose, inclusion/exclusion criteria Develop educational plan for representative diseases of autosomal dominant disorders, autosomal recessive disorders, x linked recessive and dominant disorders and mitochondrial disorders. Discuss legal, social and ethical implications of legislation that would identify Essential 3. Identify and appraise best research evidence to improve and promote quality patient outcomes. Essential 4. Utilize technology to access information, evaluate patient data, and document Essential 7. Implement health promotion and disease prevention strategies to provide culturally competent Essential 3. Identify and appraise best research evidence to improve
6 to mental health issues 8. To understand the importance of genetic factors affecting patient treatment, plan and implement appropriate patient centered care carriers of addictive genes and ban them from purchasing alcohol Article review/ paper on pharmacogenomics and patient care and promote quality patient outcomes. Essential 4. Utilize technology to access information, evaluate patient data, and document Essential 7. Implement health promotion and disease prevention strategies to provide culturally competent Essential 8. Demonstrate standards of professional, ethical and legal conduct Essential 4. Utilize technology to access information, evaluate patient data, and document Required Texts and Materials Genetics and Genomics for Nursing (Carole Kenner, Judith Lewis) ISBN ; 2013 Other required materials Computer with MAC or windows Operating System High Speed Internet Access Webcam (C910 Logitech highly recommended)
7 Refer to Angelo State University s Distance Education website for further technology requirements: Recommended Texts Sixth Edition Publication Manual of the American Psychological Association ISBN 13: Course Outline Please note the instructor reserves the right to make amendments to this topic outline as deemed appropriate. In the event that changes are necessitated, communication will be made via BB through the announcement system. This system is tied to student on file. June 5-11/week one Chapter One/Genetics and Genomics Chapter Two /Basic Concepts in Genetics and Genomics Chapter Three/ Family Context of Clinical Genetics Chapter Four/Meiosis and Mitosis Chapter Five/Aneuploidy Chapter Six /Mosaicism *June 8-11/Exam One/covers chapters 1-6 June 12-18/week two Assignments related to chapters 1-6 June 19-25/week three Chapter 7/Mendelian Inheritance Chapter 8/Genetics and Fetal Development Chapter 9/Ethical, Legal and Social Implications of the Human Genome Project Chapter 10/Prenatal Testing and Screening Chapter 11/Newborn Screening and Genetic Testing: Ethical Considerations Chapter 12/Genetic Information Non-discrimination Act Legislation *June 22-25/Exam Two/covers chapters 7-12 June 26-July 2/week four Assignments related to chapters 7-12 July 3-10/week five Chapter 13/Family history tool Chapter 14/Risk Assessment tool Chapter 15/Immunogenetics Chapter 16/Cancer Genetics Chapter 17/Impact of Environment on health: Interaction with Genes *July 6-10/Exam Three/covers chapters July 11-16/week six Assignments related to chapters 13-17
8 July 17-23/week seven Chapter 18/Common diseases with genetic linkages Chapter 19/Bipolar disorders and genetic linkages Chapter 20/Depression and genetic linkages Chapter 21/Addictive behaviors and genetic linkages Chapter 22/Autism *Exam four/covers chapters July 24-30/week eight Assignments related to chapters July 31-August 9 Paper on Pharmacogenomic Chapter 23 can be used as reference No test for this week and no final exam in this course Grading System Course grades will be dependent upon completing course requirements and meeting the student learning outcomes The following grading scale is in use for this course: A= B=80-89 C=70-79 F=<70 Evaluation and Grading Graded activities and percent of the overall course grade: Average of all quizzes 25% Average of all assignments 30% Average of all discussions 25% Paper 20% Plagiarism All students are encouraged to follow the policies regarding plagiarism as outlined in the handbook. Plagiarism at ASU is a serious topic. The Angelo State University s Honor Code gives specific details on plagiarism and what it encompasses. Plagiarism is the action or practice of taking someone else's work, idea, etc., and passing it off as one's own. Plagiarism is literary theft. In your discussions and/or your papers, it is unacceptable to copy word for word without quotation marks and the source of the quotation. We use the APA Style Manual of the American Psychological Association as a guide for all writing assignments. Quotes should be used sparingly. It is expected that you will summarize or paraphrase ideas giving appropriate credit to the source both in the body of your paper and the
9 reference list. Papers are subject to be evaluated for originality via Bb Safe Assignment or Turnitin. Resources to help you understand this policy better are available at the ASU Writing Center Below is an example how points will be deducted due to issues related to plagiarism. <10% similarity /no points will be deducted as long as the majority of the homology lies within references. If the majority of the identified homology lies within one particular article s content, 10 points will be deducted. For anything greater than 10%, I will deduct the percent similarity from final paper grade. For instance if the paper has 43 % homology and 36% of that homology comes from material online excluding references, 36 points will be deducted from the final paper grade. Course Methods: A variety of strategies may be employed to enhance skills in Pathophysiology including review of case studies and the analysis of evidence based journal articles. The primary method of instruction is through classroom discussion and will focus on 1) basic cellular alterations (pathological processes, diagnosis, manifestations), 2) contributions to the topic relative a genomics focus and 3) general knowledge regarding treatment modalities. Both individual work as well as group activity will be stressed. Polices related to this course: All students are required to follow the policies and procedures presented in the Angelo State University Undergraduate Nursing Handbook, located on the Nursing website Testing: Access to exams will be through Respondus TM Lockdown Browser and will be video recorded via Respondus Monitor. To prepare for testing using Respondus TM Monitor, see Respondus Monitor Help under the Resources tab for the course in blackboard. There are two practice quizzes: a) one is a Webcam test and b ) a short 10 questions practice quiz over ASU trivia that is not graded. These tools will be available to the student to assure accessibility. Students are highly encouraged to go through these practice quizzes in advance of taking a graded exam. This process will allow you to become familiar with the technology associated with testing and improve testing environment. GENERAL POLICIES RELATED TO THIS COURSE All students are required to follow the policies and procedures presented in the following documents:
10 Angelo State University Student Handbook located on the ASU website: ASU Undergraduate Catalog located on the ASU website ASU Nursing Program Undergraduate Student Handbook, located on the Nursing website STUDENT RESPONSIBILITY & ATTENDANCE This class is asynchronous, meaning you do not have to be on line at a certain time. There are readings which you will have to complete to be able to adequately participate in individual and group assessments. IN order to complete this course successfully you will have to participate in all activities, ie discussion boards, course projects, etc. Students are expected to engage in course activities fully and submit work by due date and time provide. The hope is that students will make substantive contributions which reflect integration of assigned materials as well as any outside readings as appropriate. Scholarly contribution is an expectation. Homework policy: All work must be turned in on the specified due date. Most of the time the homework will be submitted to assignment links in blackboard. I will announce through blackboard any deviation from this practice. Homework is assigned well in advance of a due date. Since most of the assignments are submitted through blackboard there should be very few reasons that justify late submissions. Late homework policy: For every class day that an assignment is late, 20 points will be deducted from earned grade. If I receive an from you prior to missing class, and an assignment was due to be turned into class as opposed to submission to blackboard, you will be allowed the next class date or Friday of the week you missed class to get the assignment turned in. COMMUNICATION Faculty will respond to and/or telephone messages within 24 hours during working hours Monday through Friday. Weekend messages may not be returned until Monday although reasonable attempt will be made to accommodate learning during this time. Written communication via All private communication will be done exclusively through your ASU address. Check frequently for announcements and policy changes.
11 Instructor communicates exclusively through blackboard and announcements outside of face to face classroom communication. Instructor also follows up in announcement format to all students reminders of due dates, assignments, etc. ACADEMIC INTEGRITY Academic honesty is expected on all work. Students are expected to maintain Complete honesty and integrity in their educational experiences. Any student found guilty of any form of dishonesty in academic work is subject of disciplinary action and possible expulsion from ASU. All codes and policies are set forth in the University Student Handbook of Angelo State University as well as the Department of Nursing Undergraduate Student Handbook PERSONS WITH DISABILITIES AND SPECIAL ACCOMMODATIONS REQUEST Disability Services is part of the Office of Student Affairs at Angelo State University. Angelo State s Office of Student Affairs works to ensure that qualified students with disabilities have equal access to all institutional programs and services. The office advocates responsibly for the needs of students with disabilities and educates the campus community so that others can understand and support students with disabilities. For more information on learning disabilities and how to apply for accommodations through the ASU Disability Services visit The following includes contact information for Disability Services at ASU: ada@angelo.edu Phone: Fax: Address: Houston Harte University Center, 112, ASU Station #11047, San Angelo, TX INCOMPLETE GRADE POLICY (OP Grading Procedures)
12 It is policy that incomplete grades be reserved for student illness or personal misfortune. Please contact faculty if you have serious illness or a personal misfortune that would keep you from completing course work. Documentation may be required. STUDENT ABSENCE FOR OBSERVANCE OF RELIGIOUS HOLY DAYS 1. A student who intends to observe a religious holy day should make that intention known in writing to the instructor prior to the absence. Please see ASU Operating Policy COPYRIGHT POLICY Students officially enrolled in this course should make only one printed copy of the given articles and/or chapters. You are expressly prohibited from distributing or reproducing any portion of course readings in printed or electronic form without written permission from the copyright holders or publishers. SYLLABUS CHANGES The faculty member reserves the option to make changes as necessary to this syllabus and the course content. If changes become necessary during this course, the faculty will notify students of such changes by , course announcements and/or via a discussion board announcement. It is the student s responsibility to look for such communications about the course on a daily basis.
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