BARCELONA, September 14th-16th, 2017 BRIDGING MENARINI FOUNDATION TO PAIN MEDICINE PAIN MANAGEMENT UNMET NEEDS IN ACUTE PAIN

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1 Promoted by BARCELONA, September 14th-16th, 2017 BRIDGING MENARINI FOUNDATION TO PAIN MEDICINE SCIENTIFIC PROGRAMME

SECOND JOINT MENARINI INTERNATIONAL FOUNDATION/EULAP SYMPOSIUM The first edition of this scientific event has been everybody agreed an overwhelming success.

level scientific discussion on Pain Medicine, held during the three days of the Symposium. This was the main reason why we decided to organize a second edition, this time in Barcelona.

This event will be a very interesting one and will certainly shed light on the current management of acute pain, highlighting the unmet needs still present in the third millennium.

2 SECOND JOINT MENARINI INTERNATIONAL FOUNDATION/EULAP SYMPOSIUM The first edition of this scientific event has been everybody agreed an overwhelming success. Over 400 delegates were already pre-registered, but by the date of the Opening Ceremony in Budapest (13 th of October 2016) the number exceeded 500 attendants, willing to enjoy the extremely high level scientific discussion on Pain Medicine, held during the three days of the Symposium. This was the main reason why we decided to organize a second edition, this time in Barcelona. It will be a fantastic occasion to discuss one of the most interesting aspects of pain medicine, i.e. Acute Pain. This event will be a very interesting one and will certainly shed light on the current management of acute pain, highlighting the unmet needs still present in the third millennium. As customary, the Faculty will gather topflight experts in the field. In particular, the opening lecture, devoted to the one of the great dilemmas of pain mechanisms, Bioethics in Acute Pain, will be delivered by Professor Jaime Boceta, universally considered the world number one in this topic. The current knowledge about acute pain will be then presented by outstanding speakers, who will give the background to focus on post-operative pain, the most frequent problems in pain medicine. Established and new therapeutic approaches, from the multi-modal analgesia to the futuristic therapeutic approaches like the fast-track analgesia or the procedure-specific analgesia, will complete the picture. We do hope to see you all in Barcelona, but also expect that you will become addicted to the high scientific level of these events. Your enthusiastic attendance will guarantee a large diffusion of the knowledge delivered at the Symposium and represent the best reword for the organizers. Our common efforts will certainly contribute to relieve suffering and induce wellbeing of the many pain patients worldwide. Antonio Montero Carmelo Scarpignato Giustino Varrassi 2

PRESIDENTS Scientific coordination by Antonio Montero, MD Professor of Anesthesiology and Pain Management, University of Lleida, Spain Director, Deparment of Anesthesiology, Intensive Care and Pain

Parma, Italy Associate Professor of Gastroenterology, University of Nantes, France General Secretary, World Organization for Esophageal Diseases (OESO), Paris, France Governor for Italy, American

(EuLAP) President-Elect, WIP Rome, Italy Catalan Pain Society SCIENTIFIC SECRETARIAT AND ORGANIZING COMMITTEE Anna Bertelé, MD Clinical Pharmacology & Digestive Pathophysiology Unit Department of

3 PRESIDENTS Scientific coordination by Antonio Montero, MD Professor of Anesthesiology and Pain Management, University of Lleida, Spain Director, Deparment of Anesthesiology, Intensive Care and Pain Management, Hospital Universitario Arnau de Vilanova, Lleida, Spain Carmelo Scarpignato, MD, DSc, PharmD, MPH, FRCP (London), FACP, FCP, FACG, AGAF Professor of Clinical Pharmacology, University of Parma, Italy Associate Professor of Gastroenterology, University of Nantes, France General Secretary, World Organization for Esophageal Diseases (OESO), Paris, France Governor for Italy, American College of Gastroenterology (AGA) UNDER THE AUSPICES OF: Spanish Pain Society Giustino Varrassi, MD, PhD, FIPP President, Paolo Procacci Foundation (PPF) President, European League Against Pain (EuLAP) President-Elect, WIP Rome, Italy Catalan Pain Society SCIENTIFIC SECRETARIAT AND ORGANIZING COMMITTEE Anna Bertelé, MD Clinical Pharmacology & Digestive Pathophysiology Unit Department of Clinical & Experimental Pharmacology University of Parma, Italy AISD ASSOCIAZIONE ITALIANA PER LO STUDIO DEL DOLORE Spanish Society of Anaesthesiology, Resuscitation and Pain Relief Italian Association for the Study of Pain (AISD) Antonella Paladini, MD, PhD Anesthesiology & Pain Medicine Department of Clinical Medicine, Public Health & Health Sciences University of L Aquila, Italy antonella.paladini@cc.univaq.it Paolo Procacci Foundation 3

4 SCIENTIFIC PROGRAM COMMITTEE José Luis Aguilar (Palma, Spain) Eli Alon (Zurich, Switzerland) Caterina Aurilio (Naples, Italy) Corrado Blandizzi (Pisa, Italy) Elena Catalá (Barcelona, Spain) Stefano Coaccioli (Perugia, Italy) Antonio Corcione (Naples, Italy) Francesco Di Mario (Parma, Italy) Juan Carlos Flores (Buenos Aires, Argentina) Victor Mayoral (Barcelona, Spain) Antonio Montes (Barcelona, Spain) Marco A. Narvaez Tamayo (La Paz, Bolivia) Vincenzo Piras (Cagliari, Italy) Ricardo Plancarte (San Nicolás, Mexico) Luigi Fabrizio Rodella (Brescia, Italy) Stephan Schug (Perth, WA, Australia) Rosalba Tufano (Naples, Italy) Athina Vadalouka (Athens, Greece) FACULTY José Luis Aguilar (Palma, Spain) Eli Alon (Zurich, Switzerland) Caterina Aurilio (Naples, Italy) Corrado Blandizzi (Pisa, Italy) Jaime Boceta (Sevilla, Spain) Candela Calle (Barcelona, Spain) Elena Catalá (Barcelona, Spain) Stefano Coaccioli (Perugia, Italy) Asbjørn Mohr Drewes (Copenhagen, Denmark) Juan Carlos Flores (Buenos Aires, Argentina) Giandomenico Iannetti (London, UK) Alan D. Kaye (New Orleans, LA, USA) Martin Koltzenburg (London, UK) Rudolf Likar (Klagenfurt, Austria) Francisco Macule (Barcelona, Spain) Marco Abraham Marcus (Doha, Qatar) César Margarit (Alicante, Spain) Victor Mayoral (Barcelona, Spain) Francisco Javier Medel (Barcelona, Spain) Antonio Montero (Lleida, Spain) Jordi Montero (Barcelona, Spain) Antonio Montes (Barcelona, Spain) Marco A. Narvaez Tamayo (La Paz, Bolivia) Mercé Pallàs (Barcelona, Spain) Marco Pappagallo (New York, NY, USA) Ricardo Plancarte (San Nicolás, Mexico) Gisela Roca (Badalona, Spain) Daniel Samper (Badalona, Spain) Carmelo Scarpignato (Parma, Italy) Stephan Schug (Perth, WA, Australia) Knox H. Todd (Mendoza, Argentina) Carlos Tornero (Valencia, Spain) Rosalba Tufano (Naples, Italy) Athina Vadalouka (Athens, Greece) Giustino Varrassi (Rome, Italy) Xavier Vila (Lleida, Spain) John Zeppetella (Hastingwood, UK) 4

5 THURSDAY, September 14 th, :00 a.m. Registration of the Delegates POST-GRADUATE COURSE PART I ACUTE POSTOPERATIVE PAIN (APP) STRATEGIES FOR MANAGEMENT 10:45 a.m. Presentation of the Course Antonio Montero (Lleida, Spain) Giustino Varrassi (Rome, Italy) GENERAL ASPECTS 11:00 a.m. APP: Novelties in Physiopathology José Luis Aguilar (Palma, Spain) 11:30 a.m. Clinical Features and Prevalence: (Ambulatory Surgery, Emergency Dpt., Wards...) Daniel Samper (Badalona, Spain) 12:00 p.m. Chronification of APP. Prevention and Prevalence Following Different Surgical Procedures Antonio Montes (Barcelona, Spain) 12:30 p.m. APP in the Elderly: Novelties and Precautions Gisela Roca (Badalona, Spain) 01:00 p.m. Lunch MANAGEMENT 02:00 p.m. APP Teams and Programs: Different Models and Adaptation to Hospital Environment. Measure of Results and Indicators Francisco Javier Medel (Barcelona, Spain) 02:30 p.m. Global Strategies of Treatment in APP Xavier Vila (Lleida, Spain) 03:00 p.m. Paracetamol and NSAIDs Carmelo Scarpignato (Parma, Italy) 03:30 p.m. Opioids Stephan Schug (Perth, WA, Australia) 04:00 p.m. Adjuvants Marco Pappagallo (New York, NY, USA) 5

6 OPENING CEREMONY 06:00 p.m. Welcome Addresses President of Fondazione Internazionale Menarini Alessandro Casini (Florence, Italy) Vicerector of the University of Barcelona Mercé Pallàs (Barcelona, Spain) Director of the Catalan Institute of Health Candela Calle (Barcelona, Spain) Symposium Presidents: Antonio Montero (Lleida, Spain), Carmelo Scarpignato (Parma, Italy), Giustino Varrassi (Rome, Italy) 06:30 p.m. Opening Lecture Bioethics in Acute Pain Jaime Boceta (Sevilla, Spain) 07:15 p.m. Welcome Cocktail FRIDAY, September 15 th, 2017 SYMPOSIUM SESSION I: WHAT WE KNOW ABOUT ACUTE PAIN Chairpersons: Victor Mayoral (Barcelona, Spain) Eli Alon (Zurich, Switzerland) 09:00 a.m. Pain in the Emergency Department Knox H. Todd (Mendoza, Argentina) 09:30 a.m. Acute Visceral Pain Asbjørn Mohr Drewes (Copenhagen, Denmark) 10:00 a.m. Acute and Breakthrough Pain in Cancer Patients John Zeppetella (Hastingwood, UK) 10:30 a.m. Discussion 11:00 a.m. Coffee Break 6

7 SESSION II: WHAT WE KNOW ABOUT ACUTE PAIN Chairpersons: Juan Carlos Flores (Buenos Aires, Argentina) Caterina Aurilio (Naples, Italy) 11:30 a.m. Spontaneous and Evoked Pain: Clinical Relevance for Acute Pain Conditions Jordi Montero (Barcelona, Spain) 12:00 p.m. Cortical Mechanisms of Nociception in Acute Pain Giandomenico Iannetti (London, UK) 12:30 p.m. Inflammatory Pain: Mechanisms and Consequences Stefano Coaccioli (Perugia, Italy) 01:00 p.m. Discussion 01:30 p.m. Lunch SESSION III: POST-OPERATIVE PAIN Chairpersons: José Luis Aguilar (Palma, Spain) Marco A. Narvaez Tamayo (La Paz, Bolivia) 02:30 p.m. Post-Operative Pain in Europe Elena Catalá (Barcelona, Spain) 03:00 p.m. How is Incisional Pain Different? José Luis Aguilar (Palma, Spain) 03:30 p.m. Pain and Outcome After Orthopedic and Trauma Surgery Marco Abraham Marcus (Doha, Qatar) 04:00 p.m. Discussion 04:30 p.m. Coffee Break 7

8 SESSION IV: POST-OPERATIVE PAIN: PREVENTION AND TREATMENT Chairpersons: Corrado Blandizzi (Pisa, Italy) Elena Catalá (Barcelona, Spain) 05:00 p.m. Chronic Post-Surgical Pain: Epidemiology, Risk Factors and Prevention Antonio Montes (Barcelona, Spain) 05:30 p.m. Acute Pain Mechanisms and Targets for Novel Analgesic Drugs Martin Koltzenburg (London, UK) 06:00 p.m. Guidelines for the Treatment of Acute Pain Stephan Schug (Perth, WA, Australia) 06:30 p.m. Discussion SATURDAY, September 16 th, 2017 SESSION V: ACUTE PAIN: TREATMENT Chairpersons: Antonio Montero (Lleida, Spain) Rosalba Tufano (Naples, Italy) 09:00 a.m. Patient-Controlled Analgesia: What is Left Rudolf Likar (Klagenfurt, Austria) 09:30 a.m. Interventional Approaches to Acute Pain Carlos Tornero (Valencia, Spain) 10:00 a.m. Fast Track Analgesia Francisco Macule (Barcelona, Spain) 10:30 a.m. Discussion 11:00 a.m. Coffee break 8

9 SESSION VI: ACUTE PAIN: TREATMENT Chairpersons: Athina Vadalouka (Athens, Greece) Ricardo Plancarte (San Nicolás, Mexico) 11:30 a.m. Mutimodal Analgesia: Pharmacologic Rationale and Clinical Application Alan D. Kaye (New Orleans, LA, USA) 12:00 a.m. NSAID-Opioid Combinations Carmelo Scarpignato (Parma, Italy) 12:30 p.m. Adjuvant Analgesics in Acute Pain Marco Pappagallo (New York, NY, USA) 01:00 p.m. Discussion 01:30 p.m. Lunch POST-GRADUATE COURSE PART II ACUTE POSTOPERATIVE PAIN (APP) STRATEGIES FOR MANAGEMENT CLINICAL CASES 02:30 p.m. APP Relief in Patients with Previous Chronic Pain, or Under Opioid Treatment or Addiction César Margarit (Alicante, Spain) 03:00 p.m. Clinical Cases Discussion Victor Mayoral (Barcelona, Spain) 05:30 p.m. Closing Remarks 9

10 GENERAL INFORMATION SYMPOSIUM VENUE Universitat de Barcelona Paranimf Gran Via De Les Corts Catalanes, 585 Barcelona, Spain REGISTRATION The Symposium is free to attend. Please register on the website: SECRETARIAT COUNTER The Secretariat will be open at the following times: THURSDAY, September 14 th, 2017 from a.m. to p.m. FRIDAY, September 15 th, 2017 from 08:00 a.m. to p.m. SATURDAY, September 16 th, 2017 from a.m. to p.m. OFFICIAL LANGUAGE The official language of the congress will be English. Please note that a simultaneous translation English to Spanish and Spanish to English will be provided. EUROPEAN CME (ECMEC S) ACCREDITATION An application has been submitted for European CME (ECMEC s) credits. LUNCHES AND COFFEE BREAKS Lunches and coffee breaks will be served at the congress venue. CERTIFICATE OF ATTENDANCE The certificate of attendance will be available on request at the end of the Congress at the Secretariat Counter. SPEAKERS PREVIEW ROOM / SPEAKERS LOUNGE Invited speakers must report to the Speakers Preview Room at least two hours prior to their presentation to upload and check their presentation. The Speakers Preview Room and Speaker s Lounge will be open during the following times: THURSDAY, September 14 th, 2017 from a.m. to p.m. FRIDAY, September 15 th, 2017 from a.m. to p.m. SATURDAY, September 16 th, 2017 from a.m. to p.m. TECHNICAL FACILITIES Facilities will be available for computer presentations and overhead projections. A Speakers Preview Room with PC (Powerpoint for Windows) will be available for check and preview of presentations. It is essential that speakers deliver their presentations to the Speakers Preview Room at least one hour before the session starts. 10

11 HOW TO REACH THE SYMPOSIUM VENUE NOTES METRO: The nearest metro station is called Universitat (red line L1 and purple line L2). Alternatively, you can stop at Catalunya (red line L1 and green line L3) or Passeig de Gràcia (purple line L2, green line L3 and yellow line L4), which are ten minutes walking from the venue. BUS: There are different bus routes which stop in front of the conference venue (Plaça Universitat or Aribau Gran Via). All the following routes stop within walking distance to the Universitat de Barcelona: 50, 54, 59, 63, 66, 67, 68, H12 and V13. Please beware that Barcelona buses operate vertically (V), horizontally (H) or diagonally (D), which is indicated in the name of each bus route. AIRPORT: from both Terminal 1 and Terminal 2, you can take the Aerobus which stops just in front of the symposium venue. Alternatively, you can take the train that leaves the Terminal 2 and stops at Barcelona, Passeig de Gràcia (R2), which is 15-minute walking to the venue. TAXI: you will easily distinguish Barcelona city taxis as they bear a black and yellow livery. There is a taxi rank just in front of the Universitat de Barcelona. You can also hail a taxi by calling Radio Taxi ( ). 11

12 FONDAZIONE INTERNAZIONALE MENARINI SYMPOSIA N. 349 ORGANIZING SECRETARIAT CME PROVIDER Via Guelfa Bologna (Italy) Project leader: Michela Gorgoglione m.gorgoglione@planning.it Phone Ext. 134 Mobile Fax

S C I E N T I F I C P R O G R A M

S C I E N T I F I C P R O G R A M SCIENTIFIC PROGRAM UNDER THE PATRONAGE OF EFSUMB ENDORSED COURSE UNIVERSITÀ DEGLI STUDI DI PAVIA FONDAZIONE IRCCS POLICLINICO SAN MATTEO - PAVIA SIRM - SOCIETÀ ITALIANA DI RADIOLOGIA MEDICA SIUMB - SOCIETÀ