RESIN (Research Support Information Network) Presented by: Office of the Vice Chancellor for Research Date: June 24, 2011

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1 RESIN (Research Support Information Network) Presented by: Office of the Vice Chancellor for Research Date: June 24, 2011

2 Agenda Updates & Timely Information from Research Support: Office of the VCR RSC IRB IACUC HIPAA UAMS Library BioVentures COI ORSP ORC DLAM OGSP CCTR/Core Facilities GMPA - Continuing Ed RESIN:

3 Diversity Week Linda Williams, M.S., Research Liaison Diversity Week, September 26, 2011 Research exhibits and poster session Research themes Health disparities Health care disparities Social determinants of health inequities UAMS educational/clinical programs addressing diversity, cultural competency, etc. For information, contact Nancy Dockter, MPH , RESIN:

4 New IACUC Website Bill Gurley, Ph.D., Chair, UAMS IACUC Accessible July 15, 2011 RESIN:

5 New IACUC Website Bill Gurley, Ph.D., Chair, UAMS IACUC RESIN:

6 IACUC Internal Website Bill Gurley, Ph.D., Chair, UAMS IACUC Downloadable Forms Animal Use Protocol (AUP) UAMS Form Animal Use Protocol (AUP) ACHRI Form AUP Addendum Approval Form UAMS IACUC Policies RESIN:

7 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC RESIN:

8 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC Do not use your NIH abstract!! Define all acronyms Indicate the animal species Indicate what ultimately happens to the animals (i.e. euthanasia) RESIN:

9 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC RESIN:

10 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC RESIN:

11 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC Section most frequently requiring revisions Power calculation is necessary (even for pilot studies) Contact Dr. Reid Landes (Biostatistics) for assistance prior to submission Simply saying you ve always done it this way is not acceptable RESIN:

12 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC RESIN:

13 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC RESIN:

14 Animal Use Protocol (AUP) form Bill Gurley, Ph.D., Chair, UAMS IACUC Contact Susan Steelman (Library) for assistance with literature search prior to submission RESIN:

15 AUP Addendum Form Bill Gurley, Ph.D., Chair, UAMS IACUC RESIN:

16 IACUC Policies Available Online Bill Gurley, Ph.D., Chair, UAMS IACUC Policy for Tail Clipping Rodents Policy on the Importation and Exportation of Research Animals Policy for Aseptic Survival Surgery on Rodents Policy Concerning Tumor Endpoints in Rodents Policy for Animal Transportation Policy on Blood Collections and Compound Administration in Mice and Rats Policy on Animal Euthanasia Policy on Management of Animal Pain and Distress Mouse Cage Density Policy Policy for Food and Fluid Restriction Policy on Physical Restraint of Research Animals Policy on Mouse Group Housing RESIN:

17 UAMS Transgenic Mouse Core Charles O Brien, Ph.D., Director RESIN:

18 UAMS Transgenic Mouse Core Charles O Brien, Ph.D., Director Services Consult on transgene design Consult on genotyping assay design Purify your transgene DNA for microinjection Microinject pronuclei of fertilized eggs from C57BL/6 or CB6 hybrids Provide tail clips to investigators for founder identification RESIN:

19 UAMS Transgenic Mouse Core Transgenesis RESIN:

20 UAMS Transgenic Mouse Core Pronuclear Injection RESIN:

21 UAMS Transgenic Mouse Core Timeline RESIN:

22 UAMS Transgenic Mouse Core Charles O Brien, Ph.D., Director Services Complete transgenic mouse production form Obtain IACUC approval Provide DNA with analytical gel photo Demonstrate functional screening protocol RESIN:

23 UAMS Transgenic Mouse Core Charles O Brien, Ph.D., Director Additional Information $3200 per construct Guarantee at least 2 founders; average is founder mice from 40 different DNA constructs Other services Sperm cryopreservation Re-derivation RESIN:

24 UAMS Transgenic Mouse Core Gene Targeting RESIN:

25 GMPA Continuing Education Committee Alisha Jett, GMPA Continuing Education Com. Chair Advanced Workshop: Grants Procurement Course Offered August 10, :00pm-3:00pm, Stephens Spine Building, 12th floor Presented By: Robin Rogers, SAP Training Specialist, UAMS Information Technology Janet Hopper, Director, UAMS Grants and Cost Accounting Layton Perry, Assistant Director, UAMS Procurement Services Alisha Jett, Program Manager, UAMS Department of Otolaryngology Please encourage your grants managers and administrators to attend! RESIN:

26 Grants Procurement Course Topics Alisha Jett, GMPA Continuing Educ. Committee Chair Robin Rogers - SAP Procurement Process SAP Purchasing Method Requisition is approved by release strategy in department Buyer also reviews; converts to PO Changes to PO are made by the buyer RESIN:

27 Grants Procurement Course Topics Alisha Jett, GMPA Continuing Educ. Committee Chair What To Look For / Helpful Tools Ensure G/L account numbers are correct; these put the purchase in the right budget category Ensure G/L account number is in the right value category Ensure that employees entering requisition understand requirements of the Grant Ensure right tracking code listed for taxes Wrong code means taxes might be charged when they shouldn t (i.e. PC=Patient care items, R=Research, T=Teaching, O=Other) Check SAP reports often (i.e. ZMM27, Z_Freight_Charges, CJI3) RESIN:

28 Grants Procurement Course Topics Alisha Jett, GMPA Continuing Educ. Committee Chair Janet Hopper- Grant Requirements Allowable expenses on grants Check terms and conditions for allowability Justifications required: General use items must be justified by showing need to meet the scope Grant procurement regulations follow state procurement regulations: No special treatment Monthly procurement activities Check and clear commitment items Check and clear outstanding receivables Review expenses monthly for GL errors: G/L account and material group categories RESIN:

29 Grants Procurement Course Topics Alisha Jett, GMPA Continuing Educ. Committee Chair Layton Perry- Purchasing Policies Procuring Without a Valid UAMS Purchase Order UAMS Administration Guide Policy Employee Reimbursements Prior Approval Exceptions Purchasing Card Types of Purchase Orders Small Orders Exempt by law orders. Competitive Bids Formal Bids Framework orders RESIN:

30 Grants Procurement Course Topics Alisha Jett, GMPA Continuing Educ. Committee Chair Official Functions- Policy and procedures Sole Source Requests Capital Equipment and Low Value Assets Key UAMS and State of Arkansas Contracts Amendment 54 Staples Formulary, Copiers, Fisher Scientific Releasing a purchase requisition RESIN:

31 Grants Procurement Course Topics Alisha Jett, GMPA Continuing Educ. Committee Chair Alisha Jett - Department Procurement Process Department Procurement Tips Requisition should be reviewed by PI, Grants Manager or Purchase Releaser prior to entering requisition Grant Manager Should: Check staff benefits monthly, Review cost distribution or salary changes with PI, review expenses with PI monthly, provide PI grant budgets (with projections) monthly, review commitment items regularly and resolve. RESIN:

32 Grants Procurement Course Topics Alisha Jett, GMPA Continuing Educ. Committee Chair Grant budgets / Required Reviews Staying on top of it Will provide a useful monthly grant budget template with projections and monthly required documents enclosed in one electronic form Having to Say No How to be Helpful Is this an allowable expense? Should the grant manager say no, or consider options? Knowing when workable alternatives are possible If the answer is no, provide explanations and remind of rules Balancing act: being supportive, but following guidelines RESIN:

33 UAMS HIPAA Office Vera Chenault, Director, HIPAA Office (501) Vera Chenault, JD HIPAA Campus Coordinator and UAMS Chief Privacy Officer Jennifer Sharp, JD UAMS Research Privacy Officer RESIN:

34 UAMS HIPAA Office Vera Chenault, Director, HIPAA Office Resources HIPAA Homepage All UAMS HIPAA Policies HIPAA Training for UAMS Forms Latest News RESIN:

35 UAMS HIPAA Office Vera Chenault, Director, HIPAA Office HIPAA Issues? Questions? RESIN:

36 Grant Transfers Suzanne Alstadt, Director, ORSP Transferring a Grant to UAMS Request must be made before the anticipated start date at the new organization and preferably several months in advance Request for a change of grantee organization must be submitted to the GMO GrantOriginal institution submits an Official Statement Relinquishing Interests and Rights in a Public Health Service Research Grant (PHS 3734) (relinquishing statement) RESIN:

37 Grant Transfers Suzanne Alstadt, Director, ORSP UAMS Application Includes : Face page Budget pages (current/future years) Updated bio sketches for PD/PI, existing senior/key personnel and bio sketches for any proposed new senior/key personnel If transferring on anniversary date, include progress report for current year with statement on upcoming year s goals. For all transfer applications, include statement on whether overall research plans/aims have changed from original submission, and, if so, provide updated information Updated "other support" page(s), if necessary Resources page with probable effect of the move on the project Checklist page Certification of IRB/IACUC approval, including OHRP and OLAW assurance numbers, if applicable Detailed list of equipment purchased with grant funds to be transferred to new organization (inclusion of list in transfer application from the new organization indicates acceptance of title to equipment) RESIN:

38 Grant Transfers Suzanne Alstadt, Director, ORSP Things to Keep in Mind PI must complete new ARIA project for each grant transfer Contact ORSP to create an ARIA username and password Begin the process before the PI arrives at UAMS Contact the IRB for information regarding human subjects research Contact the IACUC for information regarding vertebrate animal research Contact original institution for issues regarding equipment transfer Let ORSP know if a sub-award is involved RESIN:

39 Grant Transfers Suzanne Alstadt, Director, ORSP More Things to Keep in Mind A delay in submission of the relinquishing statement, final FSR, and final invention statement for the original institution will delay the transfer NIH will issue an NOA to UAMS to transfer the grant Prior year carryforward funds are not included in the NOA. These funds are made available later For specific grants administration issues regarding incoming grant transfers, please see RESIN:

40 Grant Transfers Suzanne Alstadt, Director, ORSP Transferring a Grant from UAMS Inform ORSP as soon as you are aware of a pending grant transfer UAMS submits an Official Statement Relinquishing Interests and Rights in a Public Health Service Research Grant (PHS 3734) (relinquishing statement) PI Completes Grant Asset Transfer form if grantpurchased equipment will be transferred. (See UAMS Policy ) RESIN:

41 Next RESIN Next RESIN September 23, 1:30p.m. Location - Walton Auditorium, Winthrop P. Rockefeller Cancer Institute, 10 th floor All RESIN presentations archived on the UAMS Research website RESIN:

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