DayOne. An initiative by BaselArea.swiss in close collaboration with the Canton of Basel-Stadt

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1 DayOne An initiative by BaselArea.swiss in close collaboration with the Canton of Basel-Stadt Swiss-Korean Life Science Symposium Thomas Brenzikofer, Member of the Management Board

2 BaselArea.swiss Mission Promote the strengths of the Basel region as a center for innovation and business. Support entrepreneurs and companies in the implementation of their innovation and business projects. Help foreign companies to establish their business in the Basel region and to connect with peers in their industries. 2

3 An initiative managed by BaselArea.swiss in close collaboration with the Canton of Basel-Stadt

4 DayOne Core Team Experts from across industry and stakeholders Michael Rebhan, Novartis Peter Groenen, Actelion Pharmaceuticals Ltd. Alain Bindels, Roche Frank Kumli, Ernst & Young Torsten Schwede, University of Basel and Swiss Institute of Bioinformatics Andreas Wicki, University Hospital Basel Erik Schkommodau, University of Applied Science and Arts Northwestern Switzerland Christian Bosshard, CSEM Laurenz Baltzer, KARGER Bram Stieltjes, University Hospital Basel André Moeri, Medgate Bhupinder Bhullar, Consultant Douglas Haggstrom, Consultant Thomas Brenzikofer, BaselArea.swiss Fabian Streiff, Department of Economic, Social and Environmental Affairs of the Canton of Basel-Stadt 4

5 DayOne Vision Create a world leading precision medicine hub respected for its impact and collaboration across silos 5

6 What s at stake? The Basel Region has a long standing tradition in reinventing itself! 6

7 What s at stake? Taking the next step forward 7

8 Patient Centric Healthcare A new concept? IT'S FAR MORE IMPORTANT TO KNOW WHAT PERSON THE DISEASE HAS THAN WHAT DISEASE THE PERSON HAS. HIPPOCRATES BC 8

9 Digitisation and Precision Medicine Putting the Patient in the middle 9

10 Digitisation and Precision Medicine Putting the Patient in the middle

11 Digitisation and Precision Medicine Putting the Patient in the middle 1 1

12 The old paradigm The valley of death Invent Test Implement Innovate Resources Valley of death Level of development S o u r c e : U S N a t i o n a l S c i e n c e F o u n d a t i o n W h a t i s a n i n n o v a t i o n e c o s y s t e m? 1 2

13 The new paradigm Patient centric innovation redefined patient population initial failed product reservoir medical need problem statement refined product proposal product experience redefine product invent test implement innovate patient in the middle product proposal product prototype revised product repositioned product 1 3

14 Bridging the valley of death The role of an innovation hub Invent Test Implement Innovate Resources Valley of death Level of development S o u r c e : U S N a t i o n a l S c i e n c e F o u n d a t i o n W h a t i s a n i n n o v a t i o n e c o s y s t e m? 1 4

15 Integrative R&D with feedback loops Turning the linear process into an iterative process Innovate Implement Invent Improve Test 1 5

16 An innovation ecosystem We have all the pieces in the Basel Region. How to use them? HIT Co Payors Medical Technology Co Social media Co Patient data Financing Risk sharing Remote care Telecom Co Community engagement Diagnostics Families & friends Social support Connectivity Employers Information companies Health literacy Providers Medical expertise Nutrition Functional Foods Self-managed patient Access Behavioral change Drugs Efficacy insights Counseling Life sciences Pharmacies Co. Food Co Retailers Co Consumer electronics S o u r c e : E r n s t & Y o u n g 1 6

17 Growing the community and projects from the bottom up Activities of the Precision Medicine Group Basel Area 2016 KICK OFF JANUARY participants giving Input on format, mission & vision, goals, topics of interest 3 WORKSHOP EVENTS 3 impulse speeches, 100+ participants, 10+ ideas discussed in 12 workshop groups DAY ONE CONFERENCE 150 registered participants, 14 project ideas, 5 keynote speeches IMPULSE EVENT Opinion Leaders from Actelion, Novartis & Roche give their view on future of diagnostics, 150 Participants COMMUNITY 400+ Members on LinkedIN: Precision-Medicine-Group- Basel-Area 1 7

18 Creating momentum The building blocks for an innovation ecosystem Connecting the components in an innovation ecosystem Community Network Connect Stakeholders Knowledge Create and share knowledge Projects Experts Access expertise Proof of Concept Assist in prototyping 1 8

19 DayOne 2017 Program Building on momentum Day One Events Health Hacking and Patient Centric Innovation - March 1st Artificial Intelligence/Machine Learning transforming healthcare April 25 Emerging markets and reverse innovation June 27 Power to Patients Who owns the data? September Innovation in Health Who is going to invest? December Day One Conference (November) One day event building on 2016 model 250+ participants mix of projects, presentation and discussion Day One Lab Prototype the lab 40m 2 space in Stücki Science Park 2 projects signed up blockchain in healthcare, Dr. Daniel Burgwinkel a maker space for science & technology savvy patients to hack their own health management solutions, Abhimanyu (Abhi) Verma, Novartis 1 9

20 DayOne Experts: Events, Workshops, Panel Discussions bringing Knowledge, Ideas & People together 2 0

21 DayOne Conference Inspiration & Open Innovation where projects and experts meet 2 1

22 DayOne Lab Prototyping the prototyping lab in 2017 what do we need? Governance - Safety - Open Collaboration - IP protocoll Operations - Skill Set & Competences - Business Model - Mentorship Infrastructure - Equipment & Materials - Engineering - Data 22

23 DayOne Lab Developing a space for cross-silo projects and rapid prototyping 2017 Test Define space to Test concept and design new space 2018 Scale-up New space containing multiple use cases. 2 3

24 Building upon the existing ecosystem DayOne as the glue to bring existing elements together 2 4

25 Building upon the existing ecosystem DayOne helping to attract further project, talent and resources 2 5

26 JOIN! Linkedin Groups: Precision Medicine Group Basel Area An initiative managed by BaselArea.swiss in close collaboration with the Canton of Basel-Stadt 2 6

27 NEXT EVENT DayOne Experts: lessons from emerging markets in precision medicine 27 June 2017 at SUD, Burgweg 7, Basel, starting from 18:00 BaselArea.swiss Register now! 2 7

28 CONTACT 2 8

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