Hypertension in adults (update) Committee meeting

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1 Hypertensi in adults (update) Committee meeting Date: 05/09/2018 Locati: Laurie Landeau Room, the Academy of Medical Sciences (41 Portland Place, Ld W1B 1QH) Minutes: Cfirmed Committee members present: Anthy Wierzbicki (Chair) (Present for notes 1 5) Liz Clark (Present for notes 1 5) Elizabeth Denver (Present for notes 1 5) Mark Glover (Present for notes 1 5) Judith Magowan (Present for notes 1 5) Terry McCormack (Present for notes 1 4D) Irene McGill (Present for notes 1 5) Richard McManus (Present for notes 1 5) Lucy Pollock (Present for notes 1 5) Mark Shapley (Present for notes 1 5) Alis Warren (Present for notes 1 5) In attendance: Catherine Baden-Daintree Senior Medical Editor, (Present for notes 1 5) NICE Serena Carville Guideline Lead, NGC (Present for notes 1 5) Margaret Cstanti Senior Health Ecomist, NGC (Present for notes 1 5) Meredith Faust Project Manager, NGC (Present for notes 1 5) Christopher Floyd Clinical Trainee, NGC (Present for notes 1 5) Audrius Stkus Trainee Research Fellow, NGC (Present for notes 1 5) Rafina Yarde Research Fellow, NGC (Present for notes 1 5) Observer: Margaret Lally Guideline committee chair of Acute corary (Present for notes 4A 5) Page 1 of 6

2 syndromes Apologies: Bryan Williams Caroline Kier Rebecca Boffa Committee member Guideline Commissiing Manager, NICE Senior Research Fellow, NGC 1. Welcome and objectives for the meeting The Chair welcomed the committee members and attendees to the tenth meeting Hypertensi in adults. The committee members and attendees introduced themselves. The Chair informed the committee that apologies had been received. These are noted above. The Chair outlined the objectives of the meeting, which included the final health ecomic model methods, the evidence reviews of malignant hypertensi and update of blood pressure targets, the committee discussi write-ups of first-, secd-, third- and fourth-step therapies. 2. Cfirmati of matter under discussi, and s of interest The Chair cfirmed that, for the purpose of managing cflicts of interest, the matter under discussi was health ecomic model methods, malignant hypertensi, blood pressure targets, and first-, secd-, third- and fourth-step therapies. The Chair asked everye to declare verbally any interests that have arisen since the last meeting. Name Role with NICE Type of inter est Descripti of interest Relevant dates Interest arose Inter est ceas ed Comme nts Richar d McMa nus Commit tee membe r Over the summer, I was involved in an ARC bid which involves work selfmitoring in collaborati with a technology partner called: m 08/2018 Specific. Page 2 of 6

3 As part of this I met with the CEO Lord Drays and discussed the potent for their help in turning our telemitoring interventi into a commerc app. He has written a letter of support for the Oxford ARC including pledging matched funding (in kind) I have no persal financ interest nor do I expect to have e (funds will go to the university) Hypertensi referrals from community pharmacy to general practice: multivariate logistic regressi analysis of patients. Albasri A, Prinjha S, McManus RJ, Sheppard JP. Br J Gen Pract Aug;68(673):e541-e550. doi: /bjgp18X Epub 2018 Jul 2. PMID: Self-Management of Postnatal Hypertensi: The SNAP-HT Tr. Cairns AE, Tucker KL, Lees P, Mackillop LH, Santos M, Velardo C, Salvi D, Mort S, Mollis J, Tarassenko L, McManus RJ; SNAP-HT Investigators. Hypertensio 2018 Aug;72(2): doi: /HYPERTENSIONAHA Epub 2018 Jul 2. PMID: Do patients actually do what we ask: patient fidelity and persistence to the Targets and Self-Management for the Ctrol of Blood Pressure in Stroke and at Risk Groups blood pressure selfmanagement interventio Schwartz CL, Seyed-Safi A, Haque S, Bray EP, Greenfield S, Hobbs FDR, Liile P, Mant J, Williams B, Mcmanus RJ. J Hypertens Aug;36(8): doi: /HJH /2018 nspecific. o 02/07/2 018 nspecific. 08/2018 nspecific. Page 3 of 6

4 38. PMID: Home blood pressure telemitoring in the 21st century. Parati G, Dolan E, McManus RJ, Ombi S. J Clin Hypertens (Greenwich) Jul;20(7): doi: /jch PMID: Guidelines for blood pressure measurement: development over 30 years. Stergiou GS, Parati G, McManus RJ, Head GA, Myers MG, Whelt PK. J Clin Hypertens (Greenwich) Jul;20(7): doi: /jch PMID: Prospective external validati of the Predicting Out-of-Office Blood Pressure (PROOF-BP) strategy for triaging ambulatory mitoring in the diagnosis and management of hypertensi: observatial cohort study. Sheppard JP, Martin U, Gill P, Stevens R, Hobbs FR, Mant J, Godwin M, Hanley J, McKinstry B, Myers M, Nunan D, McManus RJ; PROOF-BP investigators. BMJ Jun 27;361:k2478. doi: /bmj.k2478. PMID: Inadequate safety reporting in pre-eclampsia trs: a systematic evaluatio Duffy J, Hirsch M, Pealing L, Showell M, Khan KS, Ziebland S, McManus RJ; Internatial Collaborati to Harmise Outcomes in Pre-eclampsia (ihope). BJOG Jun;125(7): doi: / Epub 2017 Dec 19. Review. PMID: Intensive versus standard blood pressure treatment improves cardiovascular outcomes without any difference in patient-reported 07/2018 Specific. Part 07/2018 Specific. Part 06/2018 Specific. Part 12/2017 nspecific. o 03/2018 Specific. Page 4 of 6

5 nfinaci al outcomes. McCartney D, McManus RJ. BMJ Evid Based Med Jun;23(3): doi: /bmjebm Epub 2018 Mar 16. Review. abstract available. PMID: Qualitative study to explore the perceived burdens and benefits of a digital interventi for selfmanaging high blood pressure in Primary Care in the UK. Mort K, Dennis L, Bradbury K, Band RJ, May C, Ranery J, Liile P, McManus RJ, Yardley L. BMJ Ope 2018 May 8;8(5):e doi: /bmjopen PMID: Using the Pers-Based Approach to optimise a digital interventi for the management of hypertensio Bradbury K, Mort K, Band R, van Woezik A, Grist R, McManus RJ, Liile P, Yardley L. PLoS One May 3;13(5):e doi: /journal.pe ecollecti PMID: Current practice of usual clinic blood pressure measurement in people with and without diabetes: a survey and prospective 'mystery shopper' study in UK primary care. Stevens SL, McManus RJ, Stevens RJ. BMJ Ope 2018 Apr 12;8(4):e doi: /bmjopen PMID: o 05/2018 Specific. Part 05/2018 Specific. Part 04/2018 Specific. The Chair and a senior member of the Developer s team noted that the following members would not participate in a part of the meeting: Terry McCormack is unable to participate in fourth-step therapy discussis. Page 5 of 6

6 3. Minutes of last meeting The Chair asked the committee if it wanted any changes made to the minutes of the last meeting. The committee agreed that the minutes were a true and accurate account of the meeting. The Chair cfirmed that all matters arising had been completed or were in hand. 4. Questis and discussi A. Margaret Cstanti, Senior Health Ecomist at the NGC, presented the final health ecomic modelling methods. The committee discussed and asked questis about the final health ecomic modelling methods. B. Rafina Yarde, Research Fellow at the NGC, presented the clinical evidence and Margaret Cstanti presented the ecomic evidence for the review questi What factors indicate the need for same-day specist review (including the possible presence of malignant or accelerated hypertensi)? The committee discussed and asked questis about the evidence and drafted recommendatis. C. Rafina Yarde presented the updated clinical evidence for the review questi Should targets used for antihypertensive therapy be based blood pressure, cardiovascular risk or a combinati of both? The committee discussed and asked questis about the updated clinical evidence and edited recommendatis. D. The committee discussed the recommendatis and ratiale for the following review questis: 4.1 First-step therapy 4.2 Secd- and third-step therapy 4.3 Fourth-step therapy. 5. Any business The committee agreed to the final meeting date of Tuesday 23 April Date of next meeting: 10/10/2018 Locati of next meeting: NGC Boardroom, Royal College of Physicians, 11 St Andrew s Place, Ld NW1 4LE Page 6 of 6

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