CURRICULUM VITAE W A L T E R J A M E S J A N S E V A N R E N S B U R G

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1 CURRICULUM VITAE W A L T E R J A M E S J A N S E V A N R E N S B U R G

2 W A L T E R J A M E S J A N S E V A N R E N S B U R G PERSONAL INFORMATION Gender: Marital status: Nationality: Male Married South African EDUCATION High School: Grey College Secondary Bloemfontein Matric (2002) Matric subjects: Afrikaans First Language, HG (A) English Second Language, HG (A) German Third Language, HG (A) Biology, HG (A) Mathematics, HG (B) Physical Science, HG (B) Tertiary: University of the Free State B.Med.Sc (Human Biology) (2005) with Distinction B.Med.Sc Honours in Haematology (2007) with Distinction M.Med.Sc in Haematology (2009) Main Subjects (Honours): Haemostasis Erythrocyte and Leukocyte Defects and Examinations Immunohaematology and Haemolytic Anaemia Bloemfontein PROFESSIONAL MEMBERSHIPS HPCSA registration (Medical Scientist; MW ) Golden Key International Honours Society South African Society of Haematology (Membership # 316)

3 LANGUAGES Afrikaans Read, write and speak English Read, write and speak COMPETENCIES & COURSES Received practical training in the performance of coagulation, immunohaematology and routine haematological tests. Attended a course in Molecular techniques in Immunology at the University of the Free State, Bloemfontein (2007). Two years working experience in the routine haematology laboratory at Universitas Hospital, Bloemfontein, as part of honours degree training ( ). Attended an Introduction to Flow Cytometry (Basic) course at the BD-US Flow Cytometry Unit, Tygerberg Hospital, University of Stellenbosch, Cape Town (2008). Attended an Introduction to Flow Cytometry (Advanced) course at the BD-US Flow Cytometry Unit, Tygerberg Hospital, University of Stellenbosch, Cape Town (2008). Attended a flow Cytometry course in Lymphoma and Leukaemia at the BD-US Flow Cytometry Unit, Tygerberg Hospital, University of Stellenbosch, Cape Town (2008). Experience in non-human primate handling as senior officer at the Dept. of Haematology and Cell Biology, UFS, Bloemfontein. Attended the UK NEQAS for Blood Coagulation Annual Scientific Meeting 2009, Sheffield, England. Completed Level 1 and Level 2 First Aid Courses (2010). CONGRESS CONTRIBUTIONS 58 th Scientific and Standardization Committee meeting of the International Society on Thrombosis and Haemostasis, Liverpool, United Kingdom, 2012: Poster presentation: Evaluation of baboon platelet aggregation in a Multiplate platelet function analyzer. W Janse van Rensburg, R van Zyl, JP Roodt, S Lamprecht. 16 th Congress of the European Hematology Association, London, England, 2011: Abstract published: Tirofiban vs Abciximab: Is Tirofiban underdosed? W Janse van Rensburg, J Roodt, S Lamprecht, M Meiring, P Badenhorst. 16 th Congress of the European Hematology Association, London, England, 2011: Poster contribution: Rapid treatment of symptoms of TTP in a baboon model. J Roodt & H Feys, H Mottl, S Hou, S Lamprecht, W van Rensburg, H Deckmyn, K Vanhoorelbeke. 1 st Pathtech Congress, Durban, 2009: Presented educational session: Factor VIII determination Which Test is the Best?

4 1 st Pathtech Congress, Durban, 2009: Oral presentation: WJ Janse van Rensburg, JP Roodt, SM Meiring and PN Badenhorst. Aggrastet: Is the dosage correct? Faculty Forum 2009, Faculty of Health Sciences, UFS: Oral presentation: WJ Janse van Rensburg, JP Roodt, SM Meiring and PN Badenhorst. Aggrastet: Is the dosage correct? 14 th Congress of the European Hematology Association, Berlin, Germany, 2009: Poster presentation: W. J van Rensburg, J. Roodt, S. Lamprecht, M. Meiring, P. Badenhorst, S. Hou and H. Mottl. A von Willebrand factor inhibitory antibody effectively inhibits arterial thrombosis in a high shear rate model in baboons. 14 th Congress of the European Hematology Association, Berlin, Germany, 2009: Poster contribution: P. Badenhorst, B. van Staden, M. Meiring, W. J van Rensburg and H. Deckmyn. ADAMTS13 levels in HIV infected patients with and without TTP. 19 th Congress of the Medical Laboratory Technologists of South Africa, 2007: Oral presentation: W. J van Rensburg and P. Badenhorst. Evaluation and Implementation of the Two-Stage factor VIII Assay. Faculty Forum 2007, Faculty of Health Sciences, UFS: Oral presentation: W. J van Rensburg and P. Badenhorst. Evaluation and Implementation of the Two-Stage factor VIII Assay. ACADEMIC ADCHIEVEMENTS Received B.Med.Sc (Human Biology) degree with distinction, PPS Chairman s Scholarship 2006: One of the final six candidates nationwide. Received B.Med.Sc Hons. (Haematology) degree with distinction, Received a Kovsie Alumni Trust Award for Third best Honours student in the Faculty of Health Science, UFS, Bloemfontein, Travel grant winner at the 14 th Congress of the European Hematology Association, Berlin, Germany, Academic visit to the Laboratory for Thrombosis Research at the Katholieke Universiteit Leuven, Kortrijk Campus, Belgium, Under invitation from Professor Karen Vanhoorelbeke. Young Investigator Award at the 58th Scientific and Standardization Committee meeting of the International Society on Thrombosis and Haemostasis, Liverpool, United Kingdom, PUBLICATIONS Janse van Rensburg WJ and Badenhorst PN. Evaluation and

5 Implementation of a semi-automated Two-stage Factor VIII Assay. Medical Technology South Africa 2008; 22(2): Hendrik B. Feys, Jan Roodt, Nele Vandeputte, Inge Pareyn, Seb Lamprecht, Walter J. van Rensburg, Patricia J. Anderson, Ulrich Budde, Vernon J. Louw, Philip N. Badenhorst, Hans Deckmyn, and Karen Vanhoorelbeke. Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus). Blood 2010; 116(12): Janse van Rensburg WJ, Roodt JP, Lamprecht S, Meiring SM, Badenhorst PN. Tirofiban versus abciximab: tirofiban is administered at suboptimal dosages when evaluated in an arterial thrombosis model in non-human primates. Clinical and Experimental Medicine 2012; 12(4): Thibane VS, Ells R, Hugo A, Albertyn J, Janse van Rensburg WJ, Van Wyk PWJ, Kock JLF, Pohl CH. Polyunsaturated fatty acids cause apoptosis in C. albicans and C. dubliniensis biofilms. Biochimica et Biophysica Acta 2012; Botma J, Mogongoa LF, Jafta AD, Janse van Rensburg WJ. Reference ranges for platelet indices using Sysmex XE-2100 blood analyser. Medical Technology South Africa 2012; 26(2): Hendrik Feys, Jan Roodt, Nele Vandeputte, Inge Pareyn, Harald Mottl, Sam Hou, Seb Lamprecht, Walter J Van Rensburg, Hans Deckmyn, and Karen Vanhoorelbeke. Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons. Blood 2012; 120(17): Filip Callewaert, Jan P Roodt, Hans Ulrichts, Thomas Stohr, Walter Janse van Rensburg, Sebastiaan Lamprecht, Stefaan Rossenu, Sofie Priem, Wouter Willems, and Josefin Beate Holz. Evaluation of efficacy and safety of the anti-vwf Nanobody ALX in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura. Blood 2012; 120(17): REVIEWER FOR THE FOLLOWING JOURNALS Neurosurgery (2012) WORK EXPERIENCE : Intern Scientist at Department of Haematology and Cell Biology, UFS March 2008-October 2008: Research assistant at Department of Haematology and Cell Biology Primate Division, UFS November 2008-: Senior Officer (Medical Scientist) at the Department of Haematology and Cell Biology, UFS DUTIES AND RESPONSIBILITIES

6 Actively part of the Pre-clinical Drug Testing Facility at the Department of Haematology and Cell Biology, UFS. Development of pre-clinical animal models. Laboratory support for pre-clinical basic- and contract research. Participant in weekly departmental academic program. Involved in practical training of undergraduate medical students. Involved in lecturing undergraduate BSc students. Involved in post-graduate scientist training. Health and safety officer. Fire-warden. COURSES PRESENTED MBChB: GKV264 (Clinical Skills). B.Med.Sc (Hons): HEM601, HEM603, MBG605 BSc: MBG334, MBG344 STUDY LEADING Co-study leader for B.Tech project: Botma J. Normal reference ranges for platelet indices on the Sysmex XE2100 blood cell analyzer at the Haematology Laboratory, Universitas Hospital (CUT). (Project received prize from the Central University of Technology as best research project in the B.Tech.: Biomedical Technology course, 2010) Study leader B.Med.Sc (Honours): Van Zyl R. Standardization of the Multiplate analyzer for platelet function analysis (UFS). COMMUNITY INVOLVEMENT Gave biology and mathematics extra-classes during the September holidays for grade 12 learners from Seemahale Secondary School, Botshabelo (2004 and 2005). Was involved in the planning and practical execution of a research project for the National Science expo by learners of HTS Louis Botha. Involved in the experiential learning of grade 10 and 11 scholars interested in studying in the medical and/or science fields.