Overview of NIHR structure, and funding streams. Prof James Mason, Co-Director, RDS NE

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1 Overview of NIHR structure, and funding streams Prof James Mason, Co-Director, RDS NE

2 The National Institute for Health Research (NIHR) DH-funded, est. April 2006 Increasing applied health research and translation of basic science and for the benefit of patients and the economy Key to delivering statutory duty to promote research (Health and Social Care Act 2012) A highly integrated health research system of people, programmes, centres of excellence and systems

3 NIHR Aims Improve the health and wealth of the nation through research NHS: internationally recognised centre of research excellence Attract, develop and retain the best research professionals Commission research focused on improving health and social care Increase the opportunities for patients and public to participate Promote and protect the interests of patients and the public Faster translation of discoveries into patient benefits Maximise potential for NHS research to contribute to economic growth through the life science industry Act as a sound custodian of public money for the public good

4 NIHR Structure Investigators & Senior Investigators Faculty Trainees Associates Infrastructure Clinical Research Networks Clinical Research Facilities & Centres Universities NHS Trusts Patients & Public Research Research Projects & Programmes Research Units & Schools Research Governance Systems Systems Research Information Systems

5

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7 RESEARCH Multidisciplinary and lay panels, extensive peer review Evidence for healthcare professionals, NHS managers, public and patients High quality research proposals Well written, engaging Relevant to the brief Incremental knowledge Important question Impactful answer Honest about problems! Appropriate stakeholder engagement Relevant team and skills Realistic costing

8 Research for Patient Benefit (RfPB) Response-mode funding for research projects with patient benefit relevant to the NHS. Regional bids assessed by regional committees to ensure relevance One stage application; 3x/year researcher-led Up to 350k ( 250k pilot/feasibility) and 3 years Website:

9 Programme Grants for Applied Research (PGfAR) Prestigious awards for leading researchers with substantial applied health research track-records Coherent theme of multidisciplinary, inter-related projects, addressing a priority area - findings that will change the NHS. Programme Development Grants scheme (up to 100k and 18 months) funds preparatory research for a full application. Two stage application; 2x/year researcher-led Up to 2M and 5 years, (PDG: 100k and 18m) Website:

10 Health Technology Assessment (HTA) Funding for rigorous evidence of effectiveness and costeffectiveness of new health technologies. HTA: drugs, devices, procedures, settings of care, screening Two stage application for primary research, one stage for secondary research 3x/year researcher-led and commissioned Funding: No limit and no fixed period Website:

11 Efficacy and Mechanism Evaluation (EME) Funds collaborative 'science driven' studies understanding of biological or behavioural mechanisms and processes; exploring new scientific or clinical principles development or testing of new methodologies expectation of substantial health gain. NIHR and MRC joint-funded Two stage application; 3x/year researcher-led and commissioned Funding: No limit and no fixed period Website:

12 Health Services and Delivery Research (HS&DR) Broad range of research: quality, access and organisation of health services to improve health services. Two workstreams: (Commissioned) Healthcare Delivery Research (HDR) (Response mode) Health Services Research (HSR) Two stage application (except commissioned rapid evidence syntheses), 3x/year researcher-led and commissioned Funding: No limit and no fixed period Website:

13 Invention for Innovation (i4i) Collaborative development of innovative medical technologies or devices with potential impact in a healthcare setting. Partners: industry, NHS organisations and Higher Education Institutions. Two stage application; 2x/year researcher-led and 1x/year commissioned Funding: No limit and up to 3 years Website:

14 Public Health Research (PHR) Funds research evaluating public health interventions New knowledge on the benefits, costs, acceptability and wider impact of non-nhs interventions. Two stage application; 3x/year researcher-led and commissioned Funding: No limit and no fixed period Website:

15 Systematic Reviews UK Cochrane Centre and Cochrane Review Groups 1 call, up to 400k and 3 years Centre for Reviews and Dissemination (CRD) Technology Assessment Reviews Horizon Scanning Centre Website:

16

17 Research schools School for Primary Care Research School for Social Care Research School for Public Health Research Website:

18 Research Design Service (RDS) Research design support for health and social care researchers Helping researchers to develop high-quality patient focused research and training proposals, for submission to NIHR and other national, peerreviewed competitions. Website:

19 INVOLVE Supports public involvement in NHS, public health and social care research Helps researchers to involve patients and members of the public in developing research proposals. Promotes a research community which reflects the needs and views of patients and the public. Website:

20 NIHR Structure Investigators & Senior Investigators Faculty Trainees Associates Infrastructure Clinical Research Networks Clinical Research Facilities & Centres Universities NHS Trusts Patients & Public Research Research Projects & Programmes Research Units & Schools Research Governance Systems Systems Research Information Systems

21 FACULTY Faculty Membership: Investigators (including Senior Investigators), Associates and Trainees. Researcher/Institution-led Research training and career development programmes Integrated Academic Training for Doctors and Dentists Academic Clinical Fellowships (ACF), Clinical Lectureships (CL) Health Care Scientist (HCS) Fellowships and Clinical Academic Training (CAT pathway) for Nurses, Midwives and AHPs. Fellowships programme Methodology Programme Also clinical trials, knowledge Mobilisation, leadership Website:

22 NIHR Structure Investigators & Senior Investigators Faculty Trainees Associates Infrastructure Clinical Research Networks Clinical Research Facilities & Centres Universities NHS Trusts Patients & Public Research Research Projects & Programmes Research Units & Schools Research Governance Systems Systems Research Information Systems

23 INFRASTRUCTURE Biomedical Research Centres and Units Translational Research Partnerships Patient Safety Research Centres Clinical Research Facilities for Experimental Medicine Experimental Cancer Medicine Centres Collaborations for Leadership in Applied Health Research and Care (CLARHC) Clinical Research Networks Cancer; Stroke; Mental, Health; Diabetes; Medicines for Children; Dementias and Neurodegenerative Diseases; Primary Care; and Comprehensive. Healthcare Technology & Diagnostic Evidence Co-operatives Website:

24

25 NIHR Structure Investigators & Senior Investigators Faculty Trainees Associates Infrastructure Clinical Research Networks Clinical Research Facilities & Centres Universities NHS Trusts Patients & Public Research Research Projects & Programmes Research Units & Schools Research Governance Systems Systems Research Information Systems

26 SYSTEMS: Research Management Faster and Easier Clinical Research Promoting learning sharing between NHS providers Organisational involvement in research performance, culture and problem solving NIHR Research Support Services (RSS) framework NIHR Research Passport scheme NIHR Co-ordinated System for gaining NHS Permission (NIHR CSP), HRA work to simplify approval processes for ethical research

27 SYSTEMS: Research Information and Intelligence Clinical Practice Research Datalink UK Clinical Trials Gateway NHS Constitution Information Systems Management Information systems National Assessment Tool Research communication to stakeholders

28 SYSTEMS Supporting Growth and the Life-Sciences Industry NIHR Office for Clinical Research Infrastructure Support for NHS Organisations that sponsor or host Research NIHR Research Capability Funding NIHR Advisory Board NIHR Strategy Board

29 We are here!

30 Footnotes Really important that a new generation of clinicians engage with research as the future problem solvers for the NHS. NIHR has (rapidly) transformed the clinical research landscape providing huge opportunities for involvement Further information is available on the NIHR website ( Details of programme funding calls, alerts, deadlines and contact details Enjoy your day ask questions!

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