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1 NIHR funding programmes Twitter: NIHR YouTube: NIHRtv

2 NIHR funded research programmes on the Research Pathway Invention Evaluation Adoption Efficacy and Mechanism Evaluation (EME) Invention for Innovation (i4i) Research for Patient Benefit (RfPB) Public Health Research (PHR) Programme Grants for Applied Research (PGfAR) Health Services & Delivery Research (HS&DR) Health Technology Assessment (HTA)

3 Funding Streams Commissioned work stream Designed to meet the needs of decision makers, typically but not exclusively within NHS. Topics prioritised by expert panels and commissioning briefs advertised to address identified evidence need. Efficacy and Mechanism Evaluation Programme Health Technology Assessment Programme Health Services and Delivery Research Programme i4i Challenge Awards Public Health Research Programme

4 Funding Streams Researcher-led work stream Calls for applications on research topics/questions directly proposed by researchers. Highlight notices/ themed calls used to promote areas of need. Applications prioritised on NHS or other information need by advisory panels/boards. Dependant on programme and call: Single stage or two stage process. Primary research and evidence synthesis. Efficacy and Mechanism Evaluation Programme Health Technology Assessment Programme Health Services and Delivery Research Programme i4i Product Development Awards i4i Connect Programme Development Grants Programme Grants for Applied Research Public Health Research Programme Research for Patient Benefit Programme Systematic Reviews Programme

5 MRC-NIHR Efficacy and Mechanism Evaluation The Efficacy and Mechanism Evaluation Programme is broadly aimed at supporting science driven studies with an expectation of substantial health gain and aims to support excellent clinical science with an ultimate view to improving health or patient care. The remit includes: evaluations of new treatments includes therapeutics, small molecules and biologics psychological interventions Public Health interventions diagnostics and medical devices.

6 NIHR Health Technology Assessment Purpose and remit To deliver information about the effectiveness, costs and broader impact of healthcare treatments and tests for those who plan, provide or receive care in the NHS. Types of studies funded: randomised controlled trials and nonrandomised trials stand-alone pilot and feasibility studies (where there is evidence they will lead to a full trial) cohort studies (retrospective or prospective) adaptive designs and m.ethodological studies evidence synthesis and modelling studies

7 NIHR Health Services & Delivery Research Purpose and remit The NIHR Health Services and Delivery Research Programme funds research to produce rigorous and relevant evidence on the quality, accessibility and organisation of health services.

8 NIHR Public Health Research Purpose and remit The Public Health Research Programme funds research that evaluates public health interventions, providing new knowledge on the benefits, costs, acceptability and wider impact of non-nhs interventions intended to improve the health of the public and reduce inequalities in health. Unique characteristics Non-NHS intervention evaluation. Wide range of methodologies supported.

9 NIHR Systematic Reviews Systematic Reviews provide decision-makers with the best possible information about the effects of tests, treatments and other interventions used in health and social care. supports the production/update of reviews through 2 main funding streams: NIHR Cochrane Programme Grants scheme NIHR Cochrane Incentive Awards scheme.

10 Invention for Innovation: Who we are and what we do Translational funding scheme. Support collaborative R&D and clinical adoption. Innovative healthcare technologies. De-risk projects for follow-on investment. Led by Programme Director, Martin Hunt. Supported by a team of Programme Managers. i4i Invention YouTube: for Innovation NIHRtv

11 Research for Patient Benefit Response-mode funding programme for small grants. Maximum award 350,000 for up to three years ( 250,000 for feasibility studies towards trials, 150,000 for more upstream research with a longer pathway to patient benefit). Awards made to NHS bodies and other providers of NHS services in England with subcontracts to academic partners. Eight Regional Advisory Committees. Three funding competitions per year. Two stage application process.

12 Programme Grants for Applied Research Response mode funding for programmes of research. No limit on funding amount or duration*. Awards made to NHS organisations in England with subcontracts to academic partners. Three funding rounds per year. *Amount and period of funding depends on nature of proposed work. Funding above 2.5 million and duration more than six years will be unusual.

13 Programme Development Grants Sub-Programme of Programme Grants for Applied Research. Response mode funding for small pieces of research needed to underpin future research programme. Individual awards for 20,000 to 100,000 over a period of 6 to 18 months. Awards made to NHS organisations in England with subcontracts to academic partners. Three funding rounds per year.

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