Treatment Adherence: Defined

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From Compliance To Adherence To Concordance The Purchaser Perspective: Population Management Len Fromer, M.D., FAAFP Treatment Adherence: Defined Drugs don't work in patients who don't take them. C. Everett Koop, M.D. Patient adherence to treatment is the degree to which patients adhere to medical advice and take medicines as directed. Adherence depends not only on patient acceptance of information about the health threat itself but also on the practitioner s ability to persuade the patient that the treatment is worthwhile and on the patient s perception of the practitioner s credibility, empathy, interest, and concern. Source: Management Sciences for Health and World Health Organization 1997, 428 IPAC-RS 2011 Conference 2

The Adherence Reality NDC Health, 2003 IPAC-RS 2011 Conference 3 The Five Dimensions of Adherence Health system/ HCT-factors Social/economic factors Condition-related factors Therapy-related factors Patient-related factors HCT = healthcare team

Barriers to Adherence Complexity of the regimen Number of medications Method of administration Testing/monitoring requirements Multiple prescribers Concerns about side effects Speed of treatment effect Forgetfulness Inability to understand and act on instructions Perceptions about the nature and severity of the illness Denial of illness Asymptomatic condition Lack of motivation/incentives to change behavior Cost Limited access to healthcare services Burdensome work schedules Low health literacy Lack of instructions from HCP Physician/patient relationship Pharmacist/patient relationship Discontinuation after treatment effect is felt Source: Enhancing Prescription Medicine Adherence: A National Action Plan, National Council on Patient Information and Education. August 2007. IPAC-RS 2011 Conference 5 The Patient Experience Exists In and Out of the Physician Office Setting Within the Office Support from Practice and Family Outside of the Office Diagnosis, tests, group and individual visits, information, reminders Self-management and lifestyle changes achieve disease control

Measuring Essential Attributes of Patient Care Experiences in Primary Care Safran DG, et al. Med Care. 1998;36(5):728-739. Safran DG, et al. JGIM 2006 21(1): 13-21. Here s What a Patient-Centered Practice Should Look Like: Patient- Centered Care E-visits, group visits, improved patient wait times, wellness focus Highly visible, new features to patient Tools for improvement: technology (EHR), team building, patient registry, same-day appointments Pay for performance, improved economics/ efficiencies to provide resources for next steps Practice management, focus on leadership, creating a framework and common language for improved teamwork Patient assumes these practice qualities 8

Patient Trust as a Predictor of Adherence: Successful Behavior Change 1996 Trust Scale (percentile) 95 th 32.9% 75 th 31.7% 50 th 29.9% 25 th 28.0% 5 th 24.3% Safran DG, et al. Ann Int Med. 2003; 138(3):248-255. 0 20 25 30 35 % Successful Change What Were the Critical Elements of Success? Senior leadership vision and steadfast commitment This is who we are! Discussion at regular meetings and in conversations at every level of the organization Measurement Regularly reported results (MD-level, practice-level, system-level) System-level changes Scheduling templates, phone scripts, prioritizing continuity External momentum toward public reporting

Communication Health Literacy is a Key Factor in Chronic Disease Management Health literacy is the ability to read, understand, and act on health care Information. 1 Health literacy affects people s ability to 2 : Navigate the healthcare system, including filling out complex forms and locating providers and services Share personal information, such as health history, with providers Engage in self-care and chronic-disease management Understand mathematical concepts such as probability and risk Low literacy is associated with several adverse health outcomes, including 3 : Low health knowledge Increased incidence of chronic illness Poorer intermediate disease markers Less than optimal use of preventive health services Poor health literacy can have a negative impact on adherence 1. What is health literacy. Center for Health Care Strategies, Inc. www.chcs.org. 2. Whelton PK, et al. JAMA.2002;288:1882-1888. 3. Berkman ND, et al. Literacy and Health Outcomes. Agency for Healthcare Research and Quality, Department of Health and Human Services; January 2004. AHRQ Publication No. 04-E007-2. Communication Indications of Limited Health Literacy Behaviors that may suggest literacy problems Frequently missed appointments 2 Patient registration forms that are incomplete or inaccurately completed 1,2 Non-adherence with medication regimens 1 Patients say they are taking their medications, but laboratory tests or physiological parameters do not change in the expected fashion 1 Reluctance to take written materials along with reliance on oral explanations and demonstrations of tasks 2 Having intermediaries serve as surrogate readers 2 Responses to receiving written instructions 1 I forgot my glasses I ll read this when I get home Can you read this to me? Let me bring this home so I can discuss it with my children Responses to questions about medication regimens 1 Unable to name medications and explain what they re for 1. Weiss BD. Health Literacy and Patient Safety: Help Patients Understand: Manual for Clinicians. 2nd ed. American Medical Association Foundation and American Medical Association. 2007. 2. Baker DW et al. Arch Fam Med. 1996;5:329-334.

Traditional Care vs. Collaborative Care Issue Traditional Care Collaborative Care Relationship between patient and provider Principal caregiver? What is the goal? Providers are experts who tell patients what to do. Patients are passive. The provider. Compliance with instructions. Noncompliance is a patient problem. Providers are experts about disease. Patients are experts about their lives. Patient and provider share responsibility. Patient sets goals based on information from provider. Noncompliance is a problem of strategies. Bodenheimer T,et al. JAMA. 288: 2002, 2469-2475 Traditional Care vs. Collaborative Care Issue Traditional Care Collaborative Care How is behavior changed? External motivation Internal motivation through increased patient understanding How are problems identified? How are problems solved? By the provider By the provider By the informed patient who can recognize problems By the informed patient with the provider Bodenheimer T,et al. JAMA. 288: 2002, 2469-2475

Multimodal Approach to the Treatment of COPD Smoking Cessation Pharmacotherapy Pulmonary Rehabilitation

Population Management: Meet Stan and his COPD Stan s physician presents his case at monthly group-practice meeting Following the presentation, several physicians report having patients with uncontrolled COPD who might benefit from some of the information Stan s physician presented. What other information might be relevant for the group? What steps might the practice take to improve COPD control? Screening COPD Population Screener (COPD-PS) Simple, validated questionnaire that can help identify people age 35 in the general population who are at risk for COPD Identifies COPD symptoms and risks, as well as considers age as a screening factor This tool may lead to: Increased awareness of COPD Earlier symptom recognition Use of spirometry for accurate diagnosis Web site Available at www.copdscreener.com Martinez FJ et al. COPD. 2008;5(2):85-95.

Patient Dashboard: A Management Tool for Both Patients and Physicians Dashboard displays key data and trends Illustrates patient s current status and activity over time Example: Stan s improvement in spirometry over 6 weeks Test Patient Profile Dashboard Data Initial Visit Individual patient trends can be compared versus a comparative element (eg, the group practice, region, nation, other) For physicians, dashboards can help to determine if they re meeting targets Comparatives can be internal (among peers) and/or external (eg, GOLD guidelines) Height/Weight/BMI Average of 3 office BP measurements Diagnosis Treatment 5 11 /144 lbs/20.1 kg/m 2 (normal weight) 152/98 mm Hg Moderate COPD with partial reversibility Stage I hypertension Moderate COPD Long-acting anticholinergic medication Short-acting bronchodilator prn Stage I Hypertension Thiazide diuretic (25 mg qd) for antihypertensive therapy Consider the patient population, look beyond the individual patient Patient Registry No. of patients with COPD No. receiving pharmacotherapy Delineated according to number of medications No. of non-adherent patients No. of patients with uncontrolled COPD/No. of patients achieving GOLD guidelines Group Visits Shared medical visit Include spouses/partners and caregivers for reinforcement of messages on adherence and lifestyle modifications Continue at defined intervals for engaged patients as an educational/information forum Are there opportunities to expand care offerings?

Adherence is Not Solely a Patient Problem Adherence a critical issue for COPD care Extent to which a patient s behavior (in terms of taking medication, following a diet, modifying habits, or attending clinics) coincides with medical or health advice Terminology is intended to be non-judgmental, a statement of fact rather than of blame of the prescriber, patient, or treatment Synonyms: Compliance Concordance McDonald HP, et al. JAMA. 2002;288:2868-2879. Summary Purchasers want to pay for value delivery: Quality improvement divided by cost reduction Quality improvement cannot happen without excellent patient adherence Adherence is achieved through concordance Concordance is maximized by: improving the patient experience raising health literacy managing populations and disease states improving the care system including what happens in the community setting