Manu Thakral, PhD, ARNP

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1 Manu Thakral, PhD, ARNP CONTACT INFORMATION Kaiser Permanente Washington Health Institute Metropolitan Park East 1730 Minor Avenue, Suite 1619b Seattle, WA Phone: EDUCATION University of Massachusetts Boston College of Nursing and Health Sciences Doctor of Philosophy Nursing (Population Health track) Massachusetts General Hospital Institute of Health Professions, Charlestown, MA Master of Science in Nursing Direct Entry Program, Specialty: Adult/Women s Health Tufts University, Medford, MA Bachelor of Arts Major: Child Development, Community Health Certificate Program LICENSURE/ CERTIFICATION WA Licensed Advanced Practice Registered Nurse (APRN) ANCC certified Adult Nurse Practitioner (ANP-BC) NCC certified Women s Health Nurse Practitioner (WHNP-BC) CURRENT PROFESSIONAL POSITIONS Kaiser Permanente Washington Health Research Institute Research Associate University of Washington School of Nursing, Department of Psychosocial and Community Health Affiliate Assistant Professor Harborview Medical Center Edward Jefferson House, Medical Respite Program Advanced Practice Nurse Practitioner 2015-present 2016-present 2017-present M. Thakral Page 1

2 PROFESSIONAL ACTIVITIES/AFFILIATIONS Committees Kaiser Permanente National Nursing Research and Evidence-Based Practice Committee 2016-present KP Washington Nursing Research and Evidence-Based Practice Committee 2017-present Kaiser Permanente Health Equity and Access Team, Co-chair Opioid Crisis Forum 2015-present Ad hoc manuscript reviewer Clinical Journal of Pain Pharmacological Research Gerontology Pain Medicine 2018-present 2018-present 2017-present 2015-present Affiliations American Pain Society Academy of Integrative Pain Management Sigma Theta Tau International American Academy of Nurse Practitioners Gerontological Society of America National Organization of Nurses with Disabilities Western Institute of Nursing POSTDOCTORAL TRAINING Kaiser Permanente Washington Health Research Institute T-32 Postdoctoral Fellowship, Women s Health and Aging Mentors: Andrea LaCroix, PhD, Michael Von Korff, ScD, Susan M. McCurry, PhD Multisite collaboration on projects throughout all phases of study design and implementation with an emphasis on comparative effectiveness of opioid risk reduction policy initiatives, chronic pain epidemiology and cognitive-behavioral therapy for insomnia and aging, and health disparities in those with long term physical disabilities. DOCTORAL TRAINING University of Massachusetts Boston, College of Nursing and Health Sciences Mentors: Suzanne Leveille, PhD, RN; Ling Shi, PhD Performed SAS statistical analyses, manuscript preparation, and research presentations for the Maintenance of Balance, Independent Living, Intellect and Zest in the Elderly (MOBILIZE) Boston Study, an NIH-funded population-based prospective cohort study of novel risk factors for fall in an older population. Specific focus of research was on the functional consequences of musculoskeletal pain and stiffness in older adults. Prepared grant proposals to support dissertation research (unfunded). University of Massachusetts Boston College of Nursing and Health Sciences Mentor: Suzanne Leveille, PhD, RN Study Coordinator: An Enhanced Medication Monitoring System, an NIH-funded (SBIR) randomized M. Thakral Page 2

3 controlled trial to test the effectiveness of a program using individualized interventions and an electronic pillbox with a web-based adherence tracking. Outcomes were medication adherence and hypertension control in older persons. PAST ACADEMIC/PROFESSIONAL EXPERIENCE MGH Institute of Health Professions, Charlestown, MA Supervisor: Ursula Kelly, PhD, ANP-BC, PMHNP-BC Research Assistant: Conducted (translator-assisted) surveys targeting immigrant non-english speaking female victims of intimate partner abuse to examine health care utilization, overall health status, and barriers to health care access. Tufts University School of Medicine, Boston MA Department of Public Health Supervisor: Jeffrey Griffiths, MD, MPH Senior Research Technician: Performed laboratory techniques including plasma protein and cellular immunoassays on a cohort study of infants and their families by monitoring infection status to cryptosporidium parvum. Massachusetts General Hospital, Harvard Medical School, Boston, MA Department of Radiation Oncology Supervisor: Simon Powell, MD, PhD, FRCP Research Technician: Assayed the effects of Tirapazamine (phase III anti-cancer agent) on survival of human tumor cells using cell survival experiments and protein assays. TEACHING EXPERIENCE University of Massachusetts Boston, College of Nursing and Health Sciences NU212 Health Promotion and Teaching (Undergraduate Intermediate Writing Seminar) Course Instructor: Summer 2012, Spring 2014 University of Massachusetts Boston, College of Nursing and Health Sciences NS 668The Nurse Educator in the Academic Setting Advisor: JoAnn Mulready-Schick, EdD. MSN, RN, CNE Teaching Practicum: Spring 2012 PAST CLINICAL EXPERIENCE Group Health Research Institute, Immunization Program, Clinical Trials Boston Health Care for the Homeless Program, Barbara McInnis House Respite Care Massachusetts General Hospital Chelsea Healthcare Center, Urgent Care Preventive Medicine Associates, Quincy International Health Center Nurse Practitioner Boston Medical Center, Women s Health Outpatient Clinic Four Women, Women's Health Services, Attleboro, MA Registered Nurse M. Thakral Page 3

4 HONORS, AWARDS, SCHOLARSHIPS Carol A. Lindeman Award for New Researchers 2017 Anne Kibrick Award for Scholarly and Scientific Achievement nd Place Peer-Reviewed Paper Presentation, Eastern Nursing Research Society 2015 Association on Higher Education and Disability Scholarship 2008 Professional Nurse Traineeship Award Sigma Theta Tau Nursing Honor Society 2006-current Judith Fong Bressler Nursing Scholarship 2006 PEER-REVIEWED PUBLICATIONS Thakral, M., Shi, L., Foust, J.B., Patel, K.V., Shmerling, R. H., Bean, J. F., Leveille, S. G (2018). Persistence of pain quality in community-dwelling older adults with chronic non-cancer pain. Geriatric Nursing (in press). Thakral, M., Walker R.L., Saunders, K., Shortreed, S.M., Dublin, S., Parchman, M., Hansen, R.N., Ludman, E., Sherman, K.J., Von Korff, M. (2017). Impact of opioid dose reduction initiatives on chronic opioid therapy patients at higher risk for opioid-related adverse outcomes. Pain Medicine. 2017, Dec 6. Thakral M, Walker RL, Saunders K, Shortreed SM, Parchman M, Hansen RN, Ludman E, Sherman KJ, Dublin S, Von Korff M. (2017). Comparing pain and depressive symptoms of chronic opioid therapy patients receiving dose reduction and risk mitigation initiatives to usual care. The Journal of Pain Oct 13. Thakral, M., Shi, L., Foust, J.B., Patel, K.V., Shmerling, R. H., Bean, J. F., Leveille, S. G (2016). Pain quality descriptors in community-dwelling older adults with nonmalignant pain. PAIN, 157(12), Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2014). A stiff price to pay: Joint stiffness predicts disability in an older population: The MOBILIZE Boston Study. Journal of the American Geriatric Society, 62(10), Von Korff, M. V., Shortreed, S. M., LeResche, L. Saunders, K., Thielke, S., Thakral, M., Rosenberg, D., Turner, J. A. (2016). A longitudinal study of depression among middle-aged and senior patients initiating chronic opioid therapy. Journal of Affective Disorders, 211, Von Korff, M., Walker, R.L., Saunders, K., Shortreed, S.M., Thakral, M., Parchman, M., Hansen, R.N., Ludman, E., Sherman, K.J. and Dublin, S., (2017). Prevalence of prescription opioid use disorder among chronic opioid therapy patients after health plan opioid dose and risk reduction initiatives. International Journal of Drug Policy, 46, SUBMITTED/UNDER REVIEW Thakral, M., Shi, L., Foust, J.B., Patel, K.V., Shmerling, R. H., Bean, J. F., Leveille, S. G (2017). Persistent pain quality as a novel risk factor for disability in community-dwelling elders with chronic M. Thakral Page 4

5 pain. Thakral, M., LaCroix, A. Z., Molton, I. R. (2017). Sex/gender differences in health and functioning of individuals aging with physical disability. Dublin, S., Walker, R.L., Shortreed, S.M., Ludman, E., Sherman, K. J., Hansen, R.N., Thakral, M., Saunders, K., Parchman, M., and Von Korff, M (2017). Impact of initiatives to reduce prescription opioid risks on medically attended injuries in people using chronic opioid therapy. Sherman, K.J., Walker, R.L., Shortreed, S.M., Ludman, E., Hansen, R.N., Thakral, M., Saunders, K., Parchman, M., Dublin, S., and Von Korff, M. (2018). Trust in the doctor who manages chronic opioid therapy: results from a survey of patients with chronic non-cancer pain. Von Korff, M., Saunders, K., Dublin, S., Walker, R.L., Thakral, M., Sherman, K.J., Ludman, E., Hansen, R.N., Parchman, M., Shortreed, S.M., (2017). Impact of risk reduction initiatives on rates of opioid overdose. RESEARCH PRESENTATIONS Thakral, M., Pabiniak, C., Madziwa, L., Lapham, G., Bobb, J., Tsui, J., Boudreau, D., Campbell, C., Arnsten, J., Liebschutz, J.M., Stotts, A., Braciszewski,J., Bradley, K. (2018). Prevalence of pain conditions among persons with an opioid use disorder diagnosis in a primary care population. Accepted for podium presentation at The College on Problems of Drug Dependence 80 th Annual Scientific Meeting, Montreal, Canada. Thakral, M., Walker R.L., Saunders, K., Shortreed, S.M., Dublin, S., Parchman, M., Hansen, R.N., Ludman, E., Sherman, K.J., Von Korff, M. (2017). Group Health opioid risk reduction initiatives ( ): A case example for implementation and evaluation of promising innovations. (Podium presentation) Kaiser Permanente Center for Effectiveness & Safety Research Annual Meeting, Berkeley, CA Thakral, M., Saunders, K., Shortreed, S.M., Von Korff, M., LeResche, L., Thielke, S., Rosenberg, D., Turner, J. A., (2017). Sex/gender differences in pain-related disability among middleaged/seniors initiating chronic opioid therapy. (Podium presentation) International Association of Gerontology and Geriatrics (IAGG) 21 st World Congress, San Francisco, CA. Thakral, M., Walker R.L., Saunders, K., Shortreed, S.M., Dublin, S., Parchman, M., Hansen, R.N., Ludman, E., Sherman, K.J., Von Korff, M. (2017). Impact of opioid safety initiatives on chronic opioid therapy patients at higher risk for opioid-related problems. (Podium presentation) Western Institute of Nursing Annual Meeting, Denver, CO. Thakral, M., LaCroix, A., Molton, I. R. (2016) Sex Differences in Health and Functioning of Individuals with Physical Disabilities. (Podium presentation). Western Institute of Nursing Annual Meeting, Anaheim, CA. M. Thakral Page 5

6 Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2015) Are Pain Quality Descriptors Associated with Disability in the Older Population? (Podium presentation) Eastern Nursing Research Society Annual Meeting, Washington, DC. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2014) Persistence of pain using pain quality descriptors in the elder population: The MOBILIZE Boston Study. (Poster) Gerontological Society of America Annual Meeting, Washington, DC. Thakral, M., Leveille, S. G., Stuart-Shor, E. M. (2014) A critical analysis of multidimensional pain instruments. (Podium presentation) Eastern Nursing Research Society Annual Meeting, Philadelphia, PA. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2013) Pain quality descriptors in the elder population: The MOBILIZE Boston Study. (Symposium presentation) Gerontological Society of America Annual Meeting, New Orleans, LA. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2013) Prevalence and characteristics of pain qualities in older adults with chronic pain. (Poster) Eastern Nursing Research Society Annual Meeting, Boston, MA. Thakral, M., Shmerling, R. H., Bean, J. F., and Leveille, S. G. (2012). A stiff price to pay: Joint stiffness and disability in an older population. (Poster) Eastern Nursing Research Society Annual Meeting, New Haven, CT. Thakral, M., Shmerling, R. H., Bean, J. F., and Leveille, S. G. (2012). A stiff price to pay: Does joint stiffness predict disability in an older population? (Poster) Gerontological Society of America Annual Meeting, San Diego, CA. CLINICAL PRESENTATIONS Thakral, M. (2018). State of the science: New guidelines for opioid prescribing. (Guest lecture) Northwest Geriatrics Workforce Enhancement Center (NW GWEC) Winter 2018 Geriatric Healthcare Series. Thakral, M. (2017). New opioid prescribing guidelines and what they mean for elders with chronic pain. (Podium presentation) Elder Friendly Futures Conference, Lynwood, WA. Thakral, M. & Kishore, P. (2010). The Massachusetts model: Primary care nurse practitioners as the agent of change in treatment of alcohol and drug dependence. (Poster) National Conference of Nurse Practitioners, Chicago, IL. Thakral, M. & Plummer, P. (2011). Sexuality and intimacy. (Symposium presentation) New England Spina Bifida Conference, Sturbridge, MA. Thakral, M. & Plummer, P. ( ). Transition issues for youth with disabilities and their families. (Symposium presentation) Annual Disabilities Interclerkship, at the University of MA M. Thakral Page 6

7 Medical School. Thakral, M., (2009). Common medical problems of the addicted patient. Medical Grand Rounds Presentation, University of Massachusetts Memorial Medical Center, Worcester, MA. Thakral, M., (2008). Commencement Address for the Leadership Education in Neurodevelopmental and Related Disabilities Fellowship Program at the University of Massachusetts Medical School, Waltham, MA. Thakral, M. & Plummer, P. (2007). Health and healthy living for transitioning adolescents with disabilities. (Symposium presentation) Massachusetts Consortium for Children with Special Health Care Needs Annual Meeting. Thakral, M. (2007). How to help youth with special healthcare needs manage healthcare, education, employment and independent living. (Symposium presentation) MA and NH Regional Medical Home Learning Session, sponsored by Central MA Medical Home Network Initiative. Thakral, M. (2006) Living and learning with a disability. Kenneth B. Schwartz Center Educational Rounds, MGH Institute of Health Professions, Charlestown, MA. CURRENT FUNDED RESEARCH Kaiser Permanente Washington Development Fund 1/1/2018 to 6/30/2018 Developing Tools for Explaining Chronic Back Pain to Patients in Primary Care This project will develop and complete initial steps in developing clinician-friendly tools to help primary care providers explain chronic back pain to patients. Role: Co-Investigator National Institute on Aging/National Institutes of Health R01AG S Research Supplements to Promote Diversity in Health-Related Research awarded under parent grant: Osteoarthritis and Therapy for Sleep Study (R01AG053221, PIs: Vitiello/McCurry/Von Korff). The purpose of these funds is to improve the diversity of the research workforce are to recruit and support eligible investigators from underrepresented groups in health-related research. Role: Early Career Investigator Awardee COMPLETED FUNDED RESEARCH National Institute on Aging/National Institutes of Health T32AG Healthcare Improvement for Aging Women The purpose of this training program is to prepare postdoctoral public health scientists to produce the evidence that will guide optimum, efficient, and cost-effective healthcare practices for older women in the future. Role: Postdoctoral Fellowship Awardee M. Thakral Page 7

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