Precision Medicine & Digital Health

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1 Health Cluster Portugal, Annual Meeting 2018 Keynote Precision Medicine & Digital Health Dr. Luis Lasalvia, MD, MIB Vice President & Global Medical Officer MSC, Siemens Healthineers Unrestricted Siemens Healthcare GmbH, 2017

2 Our purpose is to enable healthcare providers to increase value Enabling better outcomes Outcomes at lower costs 2

We believe that transformational changes will make it possible to increase value Market Healthcare dynamics Trends Demographic shift Demographic shift Consumerism Population growth Industrialization

3 We believe that transformational changes will make it possible to increase value Market Healthcare dynamics Trends Demographic shift Demographic shift Consumerism Population growth Industrialization Rapid scientific progress Staff shortage Staff shortage Consolidation Shift Shift to to value-based reimbursement Growing chronic disease burden Managing Health Increasing cost cost pressure We believe medicine will become more precise Diseases will be precisely diagnosed. Therapy will be tailored to every individual. We believe value will shape care delivery Organized around the patient s medical condition. Reduced costs with no sacrifice in outcomes. We believe patients will become consumers Engaged in managing their health. They will be well informed and exercise choice. We believe healthcare will be digital Digital technologies will change the very nature of wellness and healthcare. 3

4 We enable healthcare providers to increase value by Expanding precision medicine Transforming care delivery Improving patient experience Digitalizing healthcare 4

Expanding precision medicine Highest quality imaging and laboratory results.

Diagnostic consistency through standardization, automation and quantification.

Effective risk stratification and triaging, and image guided minimally invasive therapies.

therapy outcomes Atellica diagnostics solutions delivering fast, accurate results BioMatrix for

5 Expanding precision medicine Highest quality imaging and laboratory results. Rich patient insights at the point of decision. Diagnostic consistency through standardization, automation and quantification. Personalized care leveraging omics, imaging and laboratory data integration and insights. Effective risk stratification and triaging, and image guided minimally invasive therapies. Improve diagnostic accuracy Reduce unwarranted variations Personalize when it matters Advance therapy outcomes Atellica diagnostics solutions delivering fast, accurate results BioMatrix for standardized and reproducible MR imaging regardless of patient characteristics Genetic tumor profiling enabling personalized cancer therapies ARTIS pheno enabling minimally invasive surgery for spinal fusion 5

Transforming care delivery Making care more affordable, accessible and available.

Automation, standardization and optimization of clinical pathways at departmental or system level.

Improve access to care Increase workforce productivity Optimize clinical operations Manage population health

connecting over 160 POC devices Customized and automated laboratory workflows designed to improve productivity

6 Transforming care delivery Making care more affordable, accessible and available. Enablement of team based care through shifting routine work away and fostering collaboration. Automation, standardization and optimization of clinical pathways at departmental or system level. Identification of patient cohorts and automated outreach at scale to stratified population. Improve access to care Increase workforce productivity Optimize clinical operations Manage population health Asset Management Services enabling affordable access to state-of-the-art technology POC Informatics open-access connecting over 160 POC devices Customized and automated laboratory workflows designed to improve productivity Population Health Solutions for patient engagement, care mgmt., enterprise performance opt. The IBM products mentioned herein are only available in the United States. Siemens is a distributor for these products. 6

Improving patient experience Proactive outreach and education to engage patients in managing their health and

Fewer side effects, fewer complications, shorter recovery and positive long-term therapy results.

Engage patients and families Optimize diagnostic experience Deliver outcomes that matter to patients Sustain

now promoting closer interaction between patient and caregiver TNIH 1) Assay and ARTIS enabling faster access to

7 Improving patient experience Proactive outreach and education to engage patients in managing their health and wellness. Patient friendly technology. Potential for shorter waiting time. Reduced travel needs. Fewer side effects, fewer complications, shorter recovery and positive long-term therapy results. Patients access their data and caregivers. Care continuity through automated outreach. Engage patients and families Optimize diagnostic experience Deliver outcomes that matter to patients Sustain patient loyalty IBM Phytel enabling patient engagement SOMATOM go.now promoting closer interaction between patient and caregiver TNIH 1) Assay and ARTIS enabling faster access to conclusive catheter-based treatment ehealth Patient Portal aggregating and providing access to patients personal medical data 1) TNIH = High-Sensitivity Troponin I - not available in the U.S. Product availability varies by country. 7

Digitalizing healthcare Generation of high quality imaging, laboratory and

Data aggregation for transparency, system wide interoperability and knowledge

Data analysis to generate actionable insights leveraging analytics and artificial

Operationalization through simplified user experiences and support in change

8 Digitalizing healthcare Generation of high quality imaging, laboratory and operational data. Data aggregation for transparency, system wide interoperability and knowledge sharing. Data analysis to generate actionable insights leveraging analytics and artificial intelligence. Operationalization through simplified user experiences and support in change management. Generate Aggregate Analyze Operationalize High quality data through intelligent medical devices ehealth solutions technology used in ~70% of Austrian hospitals Measurement of stroke volume for Ultrasound images Unified user experience with syngo at the scanner and syngo.via for reading/reporting 8

9 Dr. Luis Lasalvia, MD, MIB Vice President & Global Medical Officer MSC, Siemens Healthineers 511 Benedict Avenue Tarrytown. Zip code: New York, USA Thank You! E luis.lasalvia@siemens.com Unrestricted Siemens Healthcare GmbH, 2017

William Osler Health System Managed Equipment Services a new approach to effective and flexible management of imaging and diagnostic equipment.

Siemens Healthineers Case Study William Osler Health System Managed Equipment Services a new approach to effective and flexible management of imaging and diagnostic equipment. siemens.ca/healthineers William