The West-German Proton Therapy Center Essen. Facility Start up. Dirk Geismar West-German Proton Therapy Center Essen
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1 The West-German Proton Therapy Center Essen Facility Start up Dirk Geismar West-German Proton Therapy Center Essen
2 Why protons? We believe it s better for many of our patients. Improvement of outcome through dose escalation Shorter treatment times through hypofractionation Lower toxicity through lower dose to normal tissue Proton therapy provides important research opportunities
3 Environment Catchment area for patients Oncology and radiation oncology expertise Interdisciplinary cooperations e.g. chemotherapy, surgery, radiology Cooperation with medical partners who could refer patients e.g. hospitals, external specialists Capacities for in-patients Accommodation for walk in patient
4 Targets What do you want to treat? Do your cooperation partners have special interests? How many patients you want to treat? Research projects?
5 Layout How many Treatment rooms? Gantry or FixBeam Pencil Beam Scanning, Uniform Scanning or Double Scattering or everything? Out-room imaging? Patient transport system? CT and MRI etc.
6 The University Hospital of Essen 1276 beds, 27 clinics, 20 institutes employees stationary patients per year ambulatory patients per year Three focus areas: Heart and Circulation, Oncology, Transplantation (HOT)
7 Reasons for a Proton Therapy Center at the University Hospital of Essen cancer patients in Germany per year About radiotherapy cases per year Ruhr area with about 8 Mio inhabitants, about cancer patients Comprehensive Cancer Center at the Essen University Clinic, about pts. per year Proven oncology & radiation oncology expertise Particle experience from neutron therapy and eye treatments (HMI Berlin, Nice)
8 Essen Project
9 Goals of WPE 1. Proton beam scanning uniform and non-uniform 2. Image guidance out of the treatment room (pre-positioning) 3. Optimized use of treatment rooms - pre-positioning and universal patient transport system 4. Patient positioning by MRI 5. State of the art treatment of moving targets 6. Infrastructure for daily patient imaging and adaptive treatment 7. TPS development Robust 4D Trtm planning, dose tracking
10 Treatment System Configuration 230 MeV Cyclotron Fixed Horizontal and Eye Beamlines PBS Nozzle Gantries 1-3 Universal Nozzle PBS Nozzle
11 IBA Compact Cyclotron 220 Tons Internal source 230 MeV Excellent beam stability: size, shape, position Fast rf beam current control
12 IBA Beamline
13 Gantry 120 Tons Accuracy: 0, degree 0,2 1 turn/minute
14 WPE Equipment overview 3 Proton gantry rooms (IBA) 1 Proton fixed beam room (IBA) X-Ray imaging suite (Medcom) Surface Tracking (Vision AllignRT) Gating DynR 2 CT s (Philips) for planning and verification 2 MRI s (Toshiba) for planning and verification OIS Mosaiq Treatment planning system (XIO, Elekta) Patient transport system (Oncolog)
15 WPE Waiting Reception Change room Unload Load Change room Load Unload Change room Load Unload Anathesia MRI CT CT/MRI? Fixed Beams Room Gantry 1 Dedicated Scanning Nozzle Gantry 2 Universal Nozzle Gantry 3 Dedicated Scanning Nozzle
16 Patient Trolley Verification-CT Loading room Maze Treatment room
17 Full operation 20 Hours of Operations (Mo Fr) 15 hours for patient treatment 5 hours machine- and patient QA 16 Hours of Operations (Sat) 0 15 hours for patient treatments 1 16 hours for machine- and patient QA patients per day on Protons (1200 patients per year) One beam line will be optimized for pediatric patients
18 Preparation phase Staff recruitment Staff education Determine equipment options System installation & training Medical protocol development SOP generation Communication with partners and authorities Radiation protection issues Workflow training and simulation Etc.
19 Staff and training Physicians Radiation Oncologists special approval by the authorities ( Fachkunde ) collect proton expierence at other proton sites Physicists Certified Medical Physicists Special approval by authorities ( Fachkunde ) collect proton expierence at other proton sites RTT s Studynurses, Casemanager, Nurses, Secretary
20 Workflow simulation 1. Patient Registration and Documentation (Mosaiq) 2. Immobilization and Planning-CT, if needed MRI 3. Planning procedure 4. Milling (US, DS) 5. QA-Procedures 6. Treatment (Mosaiq, Medcom, TCS)
21 Permissions (Radiation protection law) Close contact to the authorities Good cooperation with the supplier Products has to fulfill legal requirements Discussion of special requirements Radiation Safety Quality Assurance Workflow Staff training Backup solutions Ongoing Process
22 Permissions (Radiation protection law) Permission for instalation Permission for operating test Permission for Clinical treatment STRIBA/IBA Permission BS 03/ Permission BS 02/ Permission BS 03/ WPE Permission BS 02/08 A Permission BS 04/
23 Reimbursement Reimbursement by Public health system Privat health insurances Foreign patients (EU and non-eu) Define indications Evidence for choosen indications Costs of treatment Reimbursement for concomittant procedures Chemotherapie Diagnostics Anaesthesia Surgery
24 Reimbursement Private Health Insurance (10-20%) no restrictions, individual cost acceptance recommended Public Health Insurance (80-90%) 2 Indications covered today Chordoma & chondrosarcoma of base of skull Uveal melanoma 15 Indications covered in a study setting Children, if treated in protocols of GPOH Individual clearance
25 It can be a long way to start a proton facility Development of cooperations and networks Communication with public and private health care leader Establish dialogue with authorities You have to recruit and train your staff worldwide. You have to convience your staff to stay.
26 Thank you!
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