Evaluation of Clinical Pharmacy Projects: A Belgian Experience
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1 Evaluation of Clinical Pharmacy Projects: A Belgian Experience Clinical Pharmacy in Hanoi: A "Wallonie-Bruxelles"- supported mission of the Université catholique de Louvain, Brussels, Belgium Paul M. Tulkens, MD, PhD with material borrowed from Olivia Dalleur (Université catholique de Louvain) The Belgian Ministry of Public Health 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 1
2 Optimizing drugs through Clinical Pharmacy... Centre of Clinical Pharmacy at UCL 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 2
3 A few definitions Pharmacology: Scientific discipline in Life Sciences that study the mecanisms of action of drugs when interacting with their targets, in order to use this information to propose specific modifications at a the level of a given pathological process insulin Pharmacotherapy: Medico-pharmaceutical discipline that uses physiopathological and pharmacological knowledge to select the appropriate drug(s) for curing a specific diseases treating diabetes requires insulin Pharmacy (From the Greek φάρμακον/pharmakôn, meaning drug, venom, poison...) is concerned with the formulation, preparation and delivery of drugs ordered by a Medical Doctor preparing and delivering long and short acting insulins 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 3
4 The problem... Will this be effective and optimized for THIS patient? insulin treating diabetes requires insulin preparing and delivering long and short acting insulins Does HE / SHE need insulin? What are the disadvantages of insulin? If insulin is chosen, does the patient know how to use it who is going to monitor effectiveness and compliance Among all available insulin, which one will provide the best benefit/cost ratio (which may not mean the cheapest) C L I N I C A L P H A R M A C Y 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 4
5 Optimizing drugs through Clinical Pharmacy... Centre of Clinical Pharmacy at UCL 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 5
6 What is Clinical Pharmacy all about? By providing "Pharmaceutical Care", the Clinical Pharmacist takes in charge the responsibility of reaching the clinical objectives of the therapy (as defined by the prescriber) in terms of therapeutic effectiveness avoidance of undesired effects optimized benefit / cost ratio This may be oriented and made effective at the level of individual patients through direct detailing activities (ward activities) of a group of patients, through the setting of processes and guidelines (centralized hospital activities) the society, through region- and nation-wide programs (including awareness actions, guidelines, and so on ) 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 6
7 The English Model of Clinical Pharmacy From the therapeutic need to the implemntation of an optmized treatment Pharmacology Analysis of the patient Goal definition Therapeutic need Recommendations et follow-up Clinical Pharmacy The patient arrives 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 7
8 How do you work that out (1)? Spinewine et al. Annals of Pharmacotherapy (2006): 40: Assemble as much information on the patient as possible Read the medical dossier and add / compare information Ask questions (politely, and only on key points at the beginning, more later on ) Construct YOUR clinical summary 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 8
9 How do you work that out (2)? Spinewine et al. Annals of Pharmacotherapy (2006): 40: Perform an "in depth" pharmaceutical analysis Have information sources ready (and updated) identify the problems if any (DRP: drug related problems) Prepare your answers to questions (HCP: helath care providers) 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 9
10 How do you work that out (3)? Spinewine et al. Annals of Pharmacotherapy (2006): 40: Make proposals, not orders or pure criticisms Discuss viva voce as much as possible Be assertive but cautious Accept responsibility and ensure the follow-up 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 10
11 How do you work that out (4)? Spinewine et al. Annals of Pharmacotherapy (2006): 40: Think about the patient leaving the hospital (after all, this is our common goal [doctors, nurses, patients, family ) Proper discharge is critical for chronic diseases (hence the example here for geriatrics) The pharmacist must write in the medical dossier (may be not at the beginning of the project, but do not delay too much ) 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 11
12 General Interests With demonstration at several points of view: Clinical effficacy of medicines iatrogenic events (ADEs), morbidity, mortality) Économic direct costs (drugs) indirect costs (adverse effects, hospital length of stay, ) Patient satisfaction Bond, Pharmacotherapy Spinewine, Louvain Medical Glen et coll., Pharmacotherapy April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 12
13 Interest for the Doctors Treatment continuity Support to the prescription and follow-up Answering to questions e.g., drug interactions, untoward effects, dosage individualization, Support for what concerns drugs Training and gain of time 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 13
14 Interest for the nursing team Support for the proper administration to the patient iv: dilution, compatibility, stability Morning, noon time, evening? Cut, mix drugs? Administration via oral/nasal gastric tubes? Information / training about drugs (why, how, how often, ) 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 14
15 How do you demonstrate the interests (1)? You must register all your activities for your-self (self-improvement) for the patient (retrieving "old" but critical information for the doctors (constructing a data base of applied knowledge) for the Medical Direction (for your-self and for the hospital) 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 15
16 How do you demonstrate the interests (2)? You must have access and write in the Medical file (Pharmaceutical consultation) for your-self (quality of your advice) for the patient (retrieving "old" but critical information) for the doctors (who can see your opinions and gain confidence in what you do) for the Medical Direction (to build up cases and statistics) 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 16
17 Building up an "intervention record" file (1) English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted Objective, basic information is essential for data retrieval Do not forget the references if you wish to be convincin 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 17
18 Building up an "intervention record" file (2) English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted When did it happen? Who has done what seems obvious, but you might be surprised 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 18
19 Building up an "intervention record" file (3) This first part relates directly to drugs Each item is important and correspond to a specific situation Only one item can be chosen (they are exclusive of each other) Sub-items should only be filled if information is available seems obvious, but you might be surprised English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 19
20 Building up an "intervention record" file (4) English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted This second part relates to the patient Also, only one answer is possible It is important to consider these apart from the drug-related reasons for intervention 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 20
21 Building up an "intervention record" file (5) Block a-g relates to drugs problems Block h-k relates to patient's problems only one choice is possible and MUST be stated (with sub-item if information is available Be accurate! English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 21
22 Building up an "intervention record" file (6) Very important items Will help you a lot for justifying your activities know who your clients are whether you are sucessful or not (self evaluation) English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 22
23 Building up an "intervention record" file (7) This is where you rally will be judged Fill up this in collaboration with a clinician first This is attractive but sometimes difficult to fill up in a meaningful way (Pharmacoeconomy is not "saving on drugs") t English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 23
24 Building up an "intervention record" file (8) English adaptation (unvalidated) from a Belgian form made by O. Dalleur (2007) - Copyrighted Final point Essential if you wish to be "part of the team" and a respected partner 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 24
25 An example of a compilation of the type of interventions over a long period 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 25
26 An example of a compilation of the type of interventions over a long period 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 26
27 An example of the importance of interventions Spinewine et al. Annals of Pharmacotherapy (2006): 40: April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 27
28 A systematic reporting in Belgium Full report of the impact of Clinical Pharmacy in Belgian Hospitals available from this web site (in French) 14 April 2011 WBI - UCL- UPH (Hanoi) :Evaluation of Clinical Pharmacy Projects (Bach Mai Hospital) 28
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