Funding Opportunities from MRC. Jacqui Oakley MRC Programme Manager, Neuroscience and Mental Health Board Early Career Neuroscientists Day

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Funding Opportunities from MRC Jacqui Oakley MRC Programme Manager, Neuroscience and Mental Health Board Early Career Neuroscientists Day At Bristol, 21 September 2015

Content About the MRC Mission Strategy Remit MRC funding schemes Studentships Fellowships Grants Applying for funding Peer-review What makes a good proposal?

Leading & partnering research Dedicated to improving human health through the best scientific research. Established 1913 Funded by UK taxpayers One of seven Research Councils

MRC mission Encourage and support high-quality research with the aim of improving human health. Produce skilled researchers. Advance and disseminate knowledge and technology to improve the quality of life and economic competitiveness in the UK and worldwide. Promote dialogue with the public about medical research.

Delivering MRC strategy New frontiers Stratified medicine Regenerative medicine Systems medicine Living a long and healthy life Mental health & wellbeing Lifestyle behaviours and health Global and population health E-health Infections Safeguarding the UK skills base Training the next generation of biomedical researchers Providing a world-class research environment MRC Fellowship Priorities Supporting skills in strategic interdisciplinary areas such as experimental medicine and bioinformatics, across interfaces (academic / clinical / industry / disciplinary / regulatory) Promoting diversity of our research base, ensuring enhanced career support and mentorship Streamlining support mechanisms to ensure funding is flexibility in supporting key career stages and transitions

MRC remit and partners MRC: basic research to early clinical trials Underpinning and aetiological Prevention Detection and diagnosis Treatment development & evaluation Phase 1 & 2 trials Other funders/partners Government departments, especially Health Other Research Councils Medical Charities Industry Technology Strategy Board Basic research Discovery Preclinical Early Clinical Late Clinical HTA MRC BBSRC NIHR Medical Charities Innovate UK

Content About the MRC Mission Strategy Remit MRC funding schemes Studentships Fellowships Grants Applying for funding Peer-review What makes a good proposal?

MRC support at different career stages Acquisition of knowledge, skills and competencies through systematic instruction Acquisition of knowledge, skills and competencies, technical and transferrable through original research Consolidation of research skills and confirmation of medical research as personal career choice Exploration of personal capacity and aptitude for independence Leading independent research plans and establishment of research team Leadership and management of own programme, team and resource Setting strategic direction, leadership and management of multiple programmes, teams and resources

MRC support at different career stages MRC Units and Institutes Studentships Post-docs on grants Skills Development Fellowships New investigator grants MRC intermediate Fellow: Transition to Independence Grant support MRC Senior Fellow Transition to Leadership Acquisition of knowledge, skills and competencies through systematic instruction Acquisition of knowledge, skills and competencies, technical and transferrable through original research Consolidation of research skills and confirmation of medical research as personal career choice Exploration of personal capacity and aptitude for independence Leading independent research plans and establishment of research team Leadership and management of own programme, team and resource Setting strategic direction, leadership and management of multiple programmes, teams and resources

Interactive Framework (map)

Supporting flexible careers Existing flexible funding policies No age limits Return from a career break Awards can be held P/T Support for parental/sick leave Mentoring, induction workshops, Annual Symposium, Increased support for flexible careers Time since PhD eligibility criteria removed Impact of career breaks Increased support for career re-entry scheme Supporting transitions

MRC Studentships

MRC PhD Studentship: Opportunities http://www.mrc.ac.uk/skills-careers/studentships/for-current-mrc-students/ MRC/AMS policy internship How research can impact policy - 3 month extension to stipend for 3 rd or 4 th year MRC students via DTP supplements Deadline: annual autumn deadline Biotechnology YES competition Annual competition to learn about commercialisation Dragon s Den style Deadline: Annually in late Spring/Summer Max Perutz Writing Award Annual competition to communicate why your research matters Deadline: Annually July Working with Industry Not only for CASE students. University can convert studentships to CASE. Must include at least 3 month placement and contribution from industry partner.

MRC Fellowship Schemes

MRC Research Fellows Great opportunities Outstanding researchers Fellowships The person The project The place Grants The project / programme The people The place (s) The thing I enjoy so much is that my work has direct application to people MRC/Academy of Medical Sciences Clinician Scientist

Fellowships: More than just a grant! Great opportunities Resources Protected time Connections, networks Potential to establish competitive position Outstanding researchers Route to independence Recognition Influence My fellowship led directly to more opportunities and collaborations MRC Clinician Scientist Fellow

Skills Development Fellowships Training at early post-doctoral career stage or enable changes in discipline Focussed on priority areas requiring capacity building at this level Quantitative Expertise: mathematics, statistics, computation and informatics applicable to any biomedical or health related data sources, from molecular to population level. Expertise at Social Science interface: with a focus on areas of health economics and/or mixed methods research. Applicants should hold a PhD (or equivalent) No eligibility rules based on time since PhD completion 3 years support: full personal salary costs, together with support for consumables expenses, travel costs and capital equipment Support a period of research overseas, at a second UK institution, or within industry

Career Development Award Career Development Award: Transition to Independence For post-doctoral researchers who are ready to make the transition to independent investigators No eligibility rules based on time since PhD completion Up to 5 years support Includes an option of 12 months research training (outside the UK, in UK industry, or at another UK research centre) The average cost per award is approximately 1m.

Senior Non Clinical Fellowship Senior Non-Clinical Fellowship: Transition to Leadership Enable independent researchers to make the transition to research leadership No eligibility rules based on time since PhD completion 7 years funding Stewardship visit in year 4 / 5 Up to 1 year at a second centre encouraged The average cost per award is approximately 2m. Only 6% CDA and 6% SNCF were academic researchers without tenure

New Investigator Research Grants Support: flexible, for high quality investigator-initiated research (clinical or non-clinical) Eligibility: UK Universities or NHS Trusts Duration: Up to 5 years - depends on the needs of the research being supported 2 years or less only for proof of principle/pilot work Support the full range of research needs Funding: no pre-set limits subject to peer review of value for money MRC wants to boost the success rates of young researchers applying for grants Sir John Savill, MRC CEO

Content About the MRC Mission Strategy Remit MRC funding relevant to you Fellowships Grants Applying for funding Peer-review What makes a good proposal?

Winning MRC Funding The Process: Peer Review Shortlisting/ Triage Panel Interview/ Board Assessment

Right idea? Right funder? Get involved in grant writing, even as observer Create a collaborative network Be on top of the literature (but not buried by it) Identify the funder s remit & priorities if in doubt, ask early! Consider suitability criteria Submission deadlines Plan ahead, everything takes longer than you think!

Fellowship Applicants Right scheme? www.mrc.ac.uk/skills-careers/applicant-skills-and-experience/?nav=main

Elements of successful proposals A clear rationale for the research Background Hypothesis Aims Preliminary data Methodology Plan B (risks are inevitable) People, environment, training for fellowships Resources well justified Write clearly for non-experts

An application may fail because Unfocused, overambitious project Unoriginal, pedestrian approach No clear hypothesis, or not hypothesis-driven Methodology not sufficiently detailed Project not intellectually challenging RO has no international standing in research area Lack of infrastructure/facilities Training element incomplete/unclear; poor training environment Right person - wrong project! And vice versa!!

Sources of advice Funder Website, helpline Named contact University Grants office University requirements Costing software Assistance in preparing grant applications Writing workshops Helpdesk Experienced colleagues and collaborators Past evaluation committee members Successful grant applicants 27

More information www.mrc.ac.uk Jacqui.Oakley@headoffice.mrc.ac.uk Julia.Dickinson@headoffice.mrc.ac.uk