13th Annual MID-SOUTH SEMINAR ON THE CARE OF THE COMPLEX NEWBORN. January 27-28, The Westin Memphis Beale Street Memphis, Tennessee

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13th Annual MID-SOUTH SEMINAR ON THE CARE OF THE COMPLEX NEWBORN January 27-28, 2017 The Westin Memphis Beale Street Memphis, Tennessee COURSE DESCRIPTION This seminar has been designed to encompass state-of-the-art practices and trends in treating the complex newborn. A faculty both clinically and academically oriented will address relevant issues and provide valuable information and insight into situations commonly presented to subspecialists and primary care providers. TARGET AUDIENCE This course is designed for neonatologists, pediatricians, family physicians, nurses and other professionals involved in treating newborns COURSE CO-DIRECTORS Ramasubbareddy Dhanireddy, M.D. Sheldon B. Korones Endowed Professor Chief, Division of Neonatology University of Tennessee Health Science Center Memphis, Tennessee Ajay J. Talati, M.D. FAAP Professor Department of Pediatrics & OB/Gyn Program Director, Neonatal-Perinatal Medicine University of Tennessee Health Science Center Memphis, Tennessee KEYNOTE SPEAKER: Laurence McCullough, Ph.D. Adjunct Professor of Ethics in Obstetrics and Gynecology and of Medical Ethics in Medicine Department of Obstetrics and Gynecology Weill Medical College of Cornell University New York, New York Distinguished Emeritus Professor Baylor College of Medicine Houston, Texas

FACULTY Umar Boston, M.D. Assistant Professor of Pediatrics and Surgery, Division of Cardiothoracic Surgery University of Tennessee Health Science Center, Director Heart Failure and Transplantation Director of Adult Congenital Heart Surgery Program, Le Bonheur Children s Hospital Chester Brown, M.D., Ph.D. Professor of Pediatrics Chief, Division of Genetics University of Tennessee Health Science Center Rev. Jack Conrad, MBA, MAR, BCC Chaplain Melody Cunningham, M.D., FAAHPM Director, Pediatric Palliative Care Mary Gaston, MSN, RN, CNML NICU Clinical Director Le Bonheur Children's Hospital Ankush Gosain, M.D., Ph.D., FACS, FAAP Associate Professor of Surgery and Pediatrics, Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Science Center, Derek M. Kelly, M.D. Associate Professor, University of Tennessee Department of Orthopedics, Assistant Residency Program Director, Campbell Clinic Orthopedics, Pediatric Orthopedic and Spinal Deformity Surgeon, Le Bonheur Children's Hospital Nick Hysmith, M.D. Assistant Professor of Pediatrics Division of Infectious Diseases University of Tennessee Health Science Center, Medical Director of Infection Prevention, Le Bonheur Children's Hospital Jay Pershad, MD, MMM Medical Director PediFlite (Pediatric/Neonatal) Transport and Transfer Center, Medical Director Telehealth, Professor of Pediatrics and Emergency Medicine, University of Tennessee Health Sciences Center, Le Bonheur Children s Hospital Divya Rana, M.D. Assistant Professor of Pediatrics Division of Neonatal - Perinatal Medicine, University of Tennessee Health Science Center Jeffrey A. Towbin, M.D. Executive Co-Director, The Heart Institute, Professor and Chief, Pediatric Cardiology, Le Bonheur Children's Hospital, St. Jude Chair in Pediatric Cardiology & Cardiac Research, Vice Chair of Pediatrics for Strategy Advancement St. Jude Children's Research Hospital, University of Tennessee Health Science Center Le Bonheur Children's Hospital Blakely Weatherford, NP Department of Neurosurgery

OBJECTIVES Upon completion of this course, the participant should be able to: Describe Zika virus and review the current literature focusing on Zika virus associated birth defects Recognize recent issues with NAS assessment and treatment options Identify potential research interests. With case based scenarios, recognize principles of stabilization during transport of perinatal encephalopathy, surgical emergencies, shock and the ELBW infant Recognize the effect of altitude during transport of the neonate in respiratory distress Describe strategies to assist referring physicians establish good communication (Telephone/Telemedicine) dispatch centers and neonatal medical control, to ensure a timely and safe transport Identify methods and key concepts of professional medical ethics Identify ethical concepts of the pregnant woman, fetus, and neonate as patient Identify implications of these concepts for the professionally responsible management of ethical challenges in perinatal medicine Understand the current scope of genomics and identify appropriate testing in clinical practice Describe the clinical findings of NEC and review research for new modalities of management Identify common orthopedic disorders in newborn and its management Describe the pathophysiology and management of heart failure in newborn Recognize the indications of heart transplant and program implementation at LBCH Assess the antibiotic usage pattern and the impact of an antibiotic stewardship program Discuss and identify ethical issues in a terminally ill neonate Understand the differences between the neurosurgical devices to treat hydrocephalus Define signs and symptoms of a shunt malfunction Identify the proper way to care for a patient with shunted hydrocephalus CREDIT Methodist Le Bonheur Healthcare designates this live activity for a maximum of 10.5 AMA PRA Category 1 Credit(s). This activity will provide 10.91 contact hours. Attendees should claim only the credit commensurate with the extent of their participation in the activity.

FRIDAY, JANUARY 27, 2017 All sessions in the Mississippi Ballroom 2nd Floor Westin Hotel 7:30 a.m. Registration / Breakfast 8:00 Welcome, Opening Remarks and Disclosures - Ramasubbareddy Dhanireddy, M.D. 8:05 Perinatal Ethics - Lawrence McCullough, Ph.D. 9:00 Genomics/Precision Medicine - Chester Brown, M.D. 9:50 Break 10:10 Zika Virus: An Overview and Update from Recent Literature - Nick Hysmith, M.D. 11:00 Neonatal Transport: Little Babies Big Challenges - Jay Pershad, M.D. NOON Lunch Provided 1:00 p.m. Care and Management of a Child with Shunted Hydrocephalus - Blakely Weatherford, FNP 2:00 Necrotizing Enterocolitis: New Insights and Implications for Patient Care - Ash Gosain, M.D., Ph.D. 2:45 Break 3:00 Neonatal Orthopedics - Derek Kelly, M.D. 3:45 Neonatal Abstinence Syndrome: Past, Present and Future - Divya Rana, M.D. 4:45 Adjourn SATURDAY, JANUARY 28, 2017 All sessions in the Mississippi Ballroom 7:30 a.m. Breakfast 7:55 Welcome - Ajay Talati, M.D. 8:00 Neonatal Heart Failure - Jeffrey Towbin, M.D. 8:50 Pediatric Heart Transplant - Umar Boston, M.D. 9:30 Choosing Wisely - Antibiotics in the NICU, Can We Change the Culture? Ajay Talati, M.D. 10:15 Break 10:30 Panel Discussion - Grappling with Uncertainty: The collision of Ethics, Palliative Care and Neonatology - Laurence McCullough, Ph.D., Melody Cunningham, M.D. Mary Gaston, R.N., Jack Conrad, Chaplain NOON Adjourn

ACCREDITATION Methodist Le Bonheur Healthcare is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Methodist LeBonheur Healthcare is an approved provider of continuing nursing education by the Tennessee Nurses Association, an accredited approver by the American Nurses Credentialing Center's Commission on Accreditation. FACULTY DISCLOSURE As a provider accredited by ACCME, Methodist Le Bonheur Healthcare must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of these relevant financial relationships will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentation. TUITION The registration fee is $240.00 for physicians; $180.00 for Nurse Practitioners and Physician Assistants; $120.00 for Residents, Fellows, Nurses and all other healthcare professionals. The fee for non-healthcare professionals is $240.00. The fee includes breakfasts, lunch and breaks. Full refund will be given for cancellation notice in writing before January 15. Cancellations after that date will be assessed a fee. No refunds will be given after January 22. Methodist Le Bonheur Healthcare reserves the right to alter, reschedule, or cancel this program. CONFERENCE SITE The conference will be held at the Westin Memphis Beale Street; 170 Lt. George W. Lee Avenue. Situated along Memphis historic Beale Street, the birthplace of rock n roll and home of the blues, the Westin is the region s premier venue for distinctive meetings. There will be a daily parking charge. CONFERENCE MATERIALS Conference materials will be available electronically on January 24, 2017. After registering for the conference you will be given a link and password to access the materials. RECOMMENDED HOTEL The Westin Memphis Beale Street 170 Lt. George W. Lee Avenue Memphis, TN 38103 901-334-5900, 800-937-8461, or www.starwoodmeeting.com/book/lebonheur Ask for the Mid South Seminar on the Care of the Complex Newborn room block. Room rate is $164.00 + tax/night if made by January 14, 2017. Guests are invited to venture out and explore the great shopping, dining and nightlife of revitalized Beale Street. Westin is part of Starwood family of hotels and resorts.

PROGRAM REGISTRATION FORM 13th Annual MID-SOUTH SEMINAR ON THE CARE OF THE COMPLEX NEWBORN January 27-28, 2017 Name: MD DO NP PA RN Other: Address: City, State, Zip: Phone: ( ) Fax: ( ) Specialty: Email: (required for CME tracking) Method of Payment Check for $ enclosed (payable to Methodist Le Bonheur Healthcare) $240 for physicians and non-healthcare professionals $180 for nurse practitioners or physician assistants $120 for residents, fellows, nurses, and other healthcare professionals Credit Card: Charge $ to my: American Express MasterCard VISA Discover Credit Card #: CSC #: Exp. Date: Card Holders Name: (Please print) Signature: (Card holder signature) Statement Address: City, State, Zip: On-line registration available at www.methodistmd.org or mail or fax your completed registration form and fees to: Continuing Medical Education Methodist Le Bonheur Healthcare 251 S. Claybrook, Ste. 512 Memphis, TN 38104 (901) 516-8933

848 Adams Avenue Memphis, Tennessee 38103