Leeds Institute of Health Sciences. Optimising intervention design to create sustainable interventions

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Leeds Institute of Health Sciences Optimising intervention design to create sustainable interventions Liz Glidewell, Rebecca Lawton, Rosie McEachan, Tom Willis, Emma Ingleson, Duncan Petty, Peter Heudtlass, Andrew Davies, Suzanne Hartley, Gemma Louch, Jane Heyhoe, Tony Jamieson, Matt Fay, Sarah Alderson, Susan Clamp and Robbie Foy.

Background Growing Literature, Stagnant Science? Interventions to support implementation have important but variable effects: audit (6-16%) education (6%) computerised prompts (3-14%) Scope to increase adoption/adherence Ivers et al. Growing literature, stagnant science? Systematic review, meta-regression and cumulative analysis of audit and feedback interventions in health care. (2014) J Gen Intern Med

Background (2) Typically interventions are adapted because of prior experience without a full understanding of how and why they work. Psychological theory offers a structured approach to identify why translation fails and evidence-based techniques to change behaviour: Capability Do they know how to? Opportunity Do they have the opportunity to? Motivation Do they want to, plan to, believe they can or are they in the habit of doing? Michie et al (2011) Implementation Science

Aims To develop cost-effective and sustainable intervention strategies to implement evidence-based recommendations with potential high impact for UK primary care 1. managing diabetes outcomes (20.8-66.2% mean 42.7%) 2. managing blood pressure (54.7-89.5% mean 71.6%) 3. avoiding risky non-steroidal prescribing (3.8-34.7% mean 11.1%) 4. prescribing anticoagulants for atrial fibrillation (0-100% mean 60%) Why selected Burden of illness Potential for significant patient benefit Scope for improvement upon current levels of adherence Likelihood of cost savings without patient harm Feasibility of measuring using routinely collected data Extent of control of individual teams or professionals.

Mixed methods study Target behaviour To select behaviours consensus panels were conducted with professionals and patients. To understand why translation fails 60 interviews with professionals. Design intervention To tailor each mode of delivery (e.g. audit reports) theoretical domains were mapped to behaviour change techniques. Prototype interventions were back translated to behaviour change techniques. Deliver intervention Acceptability and feasibility were reviewed during consensus panel meetings with patients, commissioners and clinicians. Intervention strategies were piloted with 5 practices.

Results: Menu of interventions Looking after your diabetes Patient Name: GP/ Nurse name: This is a checklist and action plan for you and your doctor or nurse to complete together. This will help you to look after your diabetes. Bring this form back whenever you have a diabetes review. When living with diabetes, your blood pressure, levels of HbA1c and cholesterol ideally need to be under the recommended levels. This will help prevent you from developing complications such as kidney and sight problems. Blood pressure HbA1c Cholesterol A chart is provided overleaf to help you / mmol/ mmol/ L Ideally, your level should be under mol record your blood pressure Your most recent level was / mmol/ mol mmol/ L measurements. The table below lists things that are important in looking after your diabetes. You may deal with one or two of these at a time depending on which is most important to you. You don t have to talk about them in the order that they are listed. Use this table to briefly record your discussions and goals. An example of how to complete the table is provided in italics. Discussed Review Date discussed Goals agreed with [initials, date (role)] Example: Physical activity and exercise 25/01/15 Get off bus a stop earlier March 15 RF (GP) Discussion of why these measurements matter Understanding prescribed treatment and taking it properly Avoidance of drugs which affect measurements, e.g. certain painkillers such as ibuprofen Smoking Alcohol intake Healthy eating Physical activity and exercise

Example of active ingredient content Shaping knowledge Salience of consequences Feedback on behaviour Comparison of behaviour Goal setting Action planning

Results continued Determinants varied by recommendation Consensus panel meetings to refine delivery e.g. the appropriateness and timing of computerised prompts were questioned for diabetes and hypertension recommendations. Risky non-steroidal prescribing Protected learning time Memory (risk factors) Audit time Consultation time Patient compliance Anticoagulation prescribing Contact with patient Secondary care knowledge Patient agenda Tailoring care (elderly, multiple conditions)

Limits Cost-effectiveness is unknown (2 crcts and process evaluations) Specifying behaviours within recommendations Generalizability of determinants (participants/study design/context/setting) Trade offs generic/focussed intervention Complex iterative process

Bottom line More patients could receive evidence-based care if interventions to change practice can be optimised. Tailoring indigenous interventions cost-effective? Optimising sustainably delivered interventions in routine health care using replicable methods. http://www.business2community.com/b2b-marketing/b2b-marketingstrategy-integrate-inbound-outbound-best-results-0850174

Leeds Institute of Health Sciences Liz Glidewell l.glidewell@leeds.ac.uk University of Leeds This presentation presents independent research funded by the UK National Institute for Health Research (NIHR) under its Programme Grants for Applied Research scheme (Grant Reference Number RP-PG-1209-10040). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. This work has been informed by the wider ASPIRE research team http://medhealth.leeds.ac.uk/info/650/aspire