28th Annual Management of the. TinyBaby. conference. 15 Category 1 Credit Hours. February 2 4, 2006

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28th Annual Management of the TinyBaby conference 15 Category 1 Credit Hours February 2 4, 2006 Disney s BoardWalk Resort Lake Buena Vista, Florida Sponsored By: Arnold Palmer Hospital for Children & Women Department of Pediatrics Division of Neonatology College of Medicine Department of Pediatrics Division of Neonatology

MANAGEMENT OF THE Tiny Baby Conference 2006 THURSDAY, FEBRUARY 2 6:30 am 12 Noon Registration 6:30 7:20 am Continental Breakfast/Exhibits Open 7:20-7:30 am Opening Remarks/Moderator.................... Gregor Alexander, MD 7:30-8:30 am NECROTIZING ENTEROCOLITIS: MORE THAN ONE DISEASE?.......................... Josef Neu, MD 8:30-9:30 am SURGICAL MANAGEMENT OF NECROTIZING ENTEROCOLITIS.................. Elizabeth A. Beierle, MD 9:30 10:30 am PREVENTION OF BRAIN INJURY IN THE PREMATURE INFANT................... Seetha Shankaran, MD 10:30 11:00 am Break/Exhibits Open 11:00 12 Noon NEONATAL CEREBRAL FUNCTION MONITORING...................... Alan R. Spitzer, MD 12:00 1:00 pm NEUROPROTECTION FOR TERM INFANTS WITH ENCEPHALOPATHY................... Seetha Shankaran, MD 1:00 Adjourn/Afternoon Open 5 hours

FRIDAY, FEBRUARY 3 6:30 am Noon Registration 6:30 7:20 am Continental Breakfast/Exhibits Open 7:20 7:30 am Moderator.................. David A. Auerbach, MD 7:30 8:30 am WHAT S NORMAL? UNDERSTANDING THE VARIANCE IN BP IN THE NICU..................... Reese H. Clark, MD 8:30 9:30 am USE AND MISUSE OF DOPAMINE AND DOBUTAMINE IN THE NICU: CHASING NUMBERS?....................... Mark J. Polak, MD 9:30 10:30 am PATENT DUCTUS ARTERIOSUS: FROM BENCH TO BEDSIDE..................... Ronald Clyman, MD 10:30 11:00 am Break/Exhibits Open 11:00 12 Noon PATENT DUCTUS ARTERIOSUS: AN ANALYSIS OF CURRENT TREATMENT OPTIONS..................... Ronald Clyman, MD 12:00 1:00 pm CONTROVERSIES IN THE TREATMENT OF THE PATENT DUCTUS ARTERIOSUS.......................... Carl Bose, MD 1:00 pm Adjourn/Afternoon Open 5 hours

SATURDAY, FEBRUARY 4 6:30 am Noon Registration 6:30 7:20 am Continental Breakfast/Exhibits Open 7:20 7:30 am Announcements/Moderator...................... David J. Burchfield, MD 7:30 8:30 am RISKY BUSINESS: PERINATAL RISK MANAGEMENT........................ Julie Williams, HCRM 8:30 9:30 am ENSURING QUALITY AND SAFETY IN NEONATAL INTENSIVE CARE........................ Robert Ursprung, MD 9:30 10:30 am WHY NEONATOLOGISTS SHOULD CARE ABOUT PERINATAL INFLAMMATION.............................. Carl Bose, MD 10:30 11:00 am Break/Exhibits Open 11:00 12 Noon FACTORS INFLUENCING NEURODEVELOPMENTAL OUTCOMES FOLLOWING NICU CARE.......................... Alan R. Spitzer, MD 12:00 1:00 pm NEONATAL CLINICAL RESEARCH IN A MULTI-HOSPITAL HEALTH CARE SYSTEM................. Robert D. Christensen, MD 1:00 pm Adjourn/Afternoon Open 5 hours TRAVEL ARRANGEMENTS For special air reservations and ticketing for this conference, please call the Florida Travel Center at 800 345-1893. Remember to use the group name Management of the Tiny Baby.

SPECIAL NEEDS The Orlando Regional Healthcare fully complies with the legal requirements of the Americans with Disabilities Act rules and regulations thereof. If any participant of the Management of the Tiny Baby conference is in need of accommodation, please do not hesitate to submit written requests, at least one month in advance, to Management of the Tiny Baby Conference Staff, MP 40, 1414 Kuhl Avenue, Orlando, FL 32806, in order to receive accommodation. Conflict-of-Interest Policy Statement As a sponsor by the ACCME, it is the policy of Orlando Regional Healthcare to require the disclosure of the existence of any significant financial interest of any other relationship a faculty member or a sponsor has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation. This information can be found in the program materials distributed at the meeting. LODGING AND MEETING LOCATION All sessions will be held at Disney's BoardWalk Resort located within the Walt Disney World Resort Complex. A block of rooms has been reserved at Disney s BoardWalk Resort. A special group rate of $205 per night, plus tax, has been arranged. Call 407-934-3372 to make your reservations or to inquire about other hotel rates. Room reservations should be received no later than January 1, 2006. After this date, rooms will be handled on a space-available basis. You may also extend your stay three days before and/or after the conference at these special group rates, if reserved in advance. Disney s Magical Express Service if you are arriving by air, Disney s legendary service starts the moment you touch down. There s no need to hassle with your luggage at baggage claim. Now through December 2006, this service is complimentary and exclusively available when you stay at a Disney Resort hotel. Official Disney motor coaches take you from Orlando International Airport to your Disney Resort hotel, while we pick up your bags and take them straight to your room. And when your meeting is over, you and your bags are whisked back from your Disney Resort hotel to the Orlando International Airport. To book, call 407-827-6777 or visit www.disneymeetings.com/magicalexpress for more details.

CONFERENCE REGISTRATION (Please type or print) Name Address City / State / Zip Phone: Home Work Hospital Address City / State / Zip Specialty RN/RRT License # E-Mail Address How did you find out about this conference? FEE SCHEDULE: Please mark one applicable to you. Entire conference charge: $450 Physician $250 PA $250 Nurse/Nurse Practitioner Per-day charge: $200 Physician $90 PA $90 Nurse/Nurse Practitioner Day $250 Resident/Intern $250 Respiratory Therapist $250 Allied Health $90 Resident/Intern $90 Respiratory Therapist $90 Allied Health 28th Annual Management of the Tiny Baby February 2-4, 2006 Credit Cards: Mastercard Visa American Express Discover Credit Card # Expiration Date Signature Date If paying with a credit card, for your convenience, you may fax registration to: 407-649-3108 or you may register on line at www.orlandoregional.com. CANCELLATION POLICY: Registration cancellation must be confirmed in writing prior to JANUARY 4, 2006. No Refunds will be given after that date. An administrative fee of $50 will be retained on all cancellations. Make check payable to Management of the Tiny Baby, Inc. Mail to: Donna Rathel, CME Dept., MP 40 Orlando Regional Healthcare 1414 Kuhl Avenue Orlando, FL 32806 800 648-0450

PROGRAM DIRECTORS - Gregor Alexander, MD Arnold Palmer Hospital for Children & Women - Willa H. Drummond, MD ORGANIZATIONAL COMMITTEE Arnold Palmer Hospital - Gregor Alexander, MD - David A. Auerbach, MD - Sally Blashfield - Marie Simpson, RN - Giselle Tse, RN Pediatrix Medical Group, Inc. - Reese Clark, MD Intermountain Health Care - Robert D. Christensen, MD - Richard Bucciarelli, MD - David J. Burchfield, MD - Willa H. Drummond, MD MODERATORS Thursday, February 2, 2006 Gregor Alexander, MD Neonatologist Chairman, Department of Pediatrics Division of Neonatology Arnold Palmer Hospital for Children & Women Orlando, Florida Saturday, February 4, 2006 David J. Burchfield, MD Professor & Chief of Neonatology Department of Pediatrics Division of Neonatology Gainesville, Florida Friday, February 3, 2006 David A. Auerbach, MD Medical Director, NICU & Newborn Services Arnold Palmer Hospital for Children & Women Corporate Medical Director, Orlando Area Pediatrix Medical Group, Inc. Orlando, Florida

DESCRIPTION This three-day conference (half-day sessions only) is designed to update, educate, and discuss common problems in newborn medicine in the clinical setting, with orientation toward the neonatologist, general practicing pediatrician, nurse, and respiratory therapist. Each year, the Program Committee carefully reviews all the attendee evaluations from the previous year in order to prepare a pertinent program presented by distinguished faculty. OBJECTIVES The participant, upon completion of this conference, will be able to: 1. Discuss the differences between Isolated Intestinal Perforations and NEC in the Premature and Mature Neonate. 2. Understand options for the surgical management of NEC. 3. Understand the pathophysiology of acute perinatal encephalopathy. 4. To define the role of cerebral function monitoring in neonatal intensive care situations. 5. Identify common management strategies for treatment of the patent ductus arteriosus. 6. Understand the mechanisms that regulate ductus arteriosus patency and closure in the preterm infant. 7. Understand the role in perinatal inflammation in preterm labor. 8. Review pharmacokinetics of dopamine and dobutamine in neonates. 9. Participants will learn the results of neonatal clinical trials using a multihospital consortium. ACCREDITATION This activity has been planned and implemented in accordance with the essential areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Orlando Regional Healthcare and Shands Children s Hospital. Orlando Regional Healthcare is accredited by the ACCME to provide continuing medical education for physicians. Orlando Regional Healthcare designates this education activity for a maximum of 15.0 credits in Category 1 credit toward the AMA Physician s Recognition Award. Each physician should claim only those credits that he/she actually spent in the educational activity. 15.0 credits for nurses have been approved by Florida Provider # FBN2459.

GUEST FACULTY Elizabeth A. Beierle, MD Assistant Professor of Surgery Department of Surgery Shands Children s Hospital Gainesville, Florida Carl Bose, MD Chief, Division of Neonatal- Perinatal Medicine University of North Carolina NC Children s Hospital Chapel Hill, North Carolina Robert D. Christensen, MD Director of Neonatology Research Intermountain Health Care Medical Director, Neonatology McKay-Dee Hospital Center Ogden, Utah Reese H. Clark, MD Director of Clinical Research Center for Research & Education Pediatrix Medical Group, Inc. Sunrise, Florida Ronald I. Clyman, MD Professor of Pediatrics Senior Staff Cardiovascular Research Institute University of California, San Francisco San Francisco, California Josef Neu, MD Professor of Pediatrics Shands Children s Hospital Gainesville, Florida Mark J. Polak, MD Associate Professor West Virginia University School of Medicine Morgantown, West Virginia Seetha Shankaran, MD Director, Neonatal Perinatal Medicine Children s Hospital of Michigan Detroit, Michigan Alan R. Spitzer, MD Senior Vice President and Director The Center for Research and Education Pediatrix Medical Group Sunrise, Florida Robert Urspring, MD Acting Co-Director of Quality Improvement Pediatrix Medical Group, Inc. Neonatologist Cook Children s Medical Center Fort Worth, Texas Julie Williams, HCRM Risk Manager for Women and Newborn Services Risk Management Department The Arnold Palmer Hospital for Children & Women Orlando, Florida 4848-36508 11/03c