FILING REF.: The precedino University of California (UCSD) Agreement was dated ~ San Diego Campus June 23, 199.9

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BIN #: 1956006144Al DATE: May 28, 2004 INSTITUTION: FILING REF.: The precedino University of California (UCSD) Agreement was dated San Diego Campus June 23, 199.9 CA The rates approved in this agreement are for USe on grants, contracts and other agreements ith the Federal Government, subject to the conditions in Section III. SECTION I: FACILITIES AND ADMINISTRATIVE COST RATES* RATE TYPES: FIXED FINAL PROVo (PROVISIONAL) PRED. (PREDETERMINED) EFFECTIVE PERIOD TYPE FROM TO RATE (%) LOCATIONS APPLICABLE TO PRED. 07/01/02 06/30/04 52.0 On-Campus (1) Organized Research PRED. 07/01/04 06/30/05 53.5 On-Campus (1) Organized Research PRED. 07/01/05 06/30/06 54.0 on-eampus(l) Organized Research PRED. 07/01/06 06/30/08 54.5 On-Campus (1) Organized Research PRED. 07/01/02 06/30/08 26.0 Off-Camp. (1) Organized Research PRED. 07/01/02 06/30/08 53.0 On-Campus (1) Instruction PRED. 07/01/02 06/30/08 26.0 Off-Camp. (1) Instruction PRED. 07/01/02 06/30/04 40.0 On-eampus(1) Other Sponsored Act. FRED. 07/01/02 06/30/04 24.5 Off-Camp. (1) Other Sponsored Act. PRED. 07/01/04 06/30/08 45.0 On-Capus(l) Other Sponsored Act. PRED. 07/01/04 06/30/08 26.0 Off-Camp. (1) Other Sponsored Act. PRED. 07/01/02 06/30/04 52.S On-Campus (2) Organized Research PRED. 07/01/02 06/30/04 26.8 Off-Camp. (2) Organized Research PRED. 07/01/02 06/30/04 57.0 On-Campus (2) Instruction PRED. 07/01/02 06/30/04 30.0 Off-Camp. (2) Instruction PRED. 07/01/02 06/30/04 40.0 On-Campus (2) Other Sponsored Act. PRED. 07/01/02 06/30/04 24.5 Off-Camp. (2) Other Sponsored Act. PRED. 07/01/02 06/30/04 13.0 (A) (1) Organized Research FRED. 07/01/04 06/30/08 16.0 (A) (1) Organized Research PR.ED. 07/01/02 06/30/04 26.5 (Bl (1) Organized Research PRED. 07/01/04 06/30/08 28.0 (B) (I) Organized Research PRED. 07/01/04 06/30/08 19.0 (el (1) Organized Research PROVo 07 / 0 1 / 0 a UNTIL 1'11ENDED Use same rates and conditions as those cited for fiscal year ending June 30, 2008. (11 Facilities & Adin Rates (2) Facilities & Admin Rates-DOD Contracts Only (Al Nimi tz Marine Facility, Marine Physical Laboratories (:8) Gen Clinical Res Ctr (On-Campus) tel Gen Clinical Res Ctr (Off-Campus) *BASE: Modified total direct costs, consisting of all salaries and wages, fringe benefite, materials, supplies, services, travel and Bubgrante and subcontracts up to the first $25.000 of each subgrant or subcontract (regardless of the period covered by the eubgrant or subcontract). Modified total direct costs shall exclude equipment, capital expenditures, charges for patient care, tuition remission, rental costs of off-eite facilities. echolarships. and fellowahius as well as the portion of each eubgrant and subcontract in excess of- $25,000. (1) U20236 TOTAL P.02

INSTITUTION: University of California (UCSD). San Diego Campus AGREEMENT DATE: May 28, 2004 SECTION II: SPECIAL REMARKS TREATMENT OF FRINGE BENEFITS.r This organization charges the actual cost of each fringe benefit direct to Federal projects. However, it uses a fringe benefit rate which is applied to salaries and wages in budgeting fringe benefit costs under project proposals. The fringe benefits listed below are treated as direct costs. TREATr-lENT OF PAID ABSENCES Vacation, holiday, sick leave pay and other paid absences are included in salaries and wages and are claimed on grants, contracts and other agreements as part of the normal cost for salaries ad wages. Separate claims for the coste of these paid absences are not made. A separate charge is made to Federal projects for vacation benefit leave accruals. DEFINITION OF EUIPMENT Effective July 1, 1999, equipment is defined as tangible nonexpendable personal property havir.g a useful life of more than one year and an acquisition cost of $1,500 or more per unit. DEFINITION OF ON-CAMPUS, OFF-CAMPUS SPECLAL RATES DEFINITION OF OFF-CAMPUS RATE The off-campus rate is applicable to those projects conducted at facilities not owned or leased by the University. However, if the project is conducted in leased space and lease costs are directly charged to the project, then the off-campus rate must be used. PRECTS CONDUCTED ENTIRELY ON-CAMPUS OR ENTIRELY OFF-CAMPUS: Projects conducted entirely on-campus or entirely off-campus will be applied the on-campus or off-campus rate respectively. PRECTS CONDUCTED PA.TIALLY OFF-CAMPUS AND PARTIALLY ON-CAMPUS: If the project involves work at both on-campus and off-campus sites, either the on-campus or off-campus rate generally should be applied, consistent with where the majority of the work is to be performed. Salary cost is generally accepted as a measure of work performed in terms of the total project. USE OF EOTH ON-CAMPUS A-"ID OFF-CAMPUS UTES The use of both on-campus and off-campus rates for a given project may be justified if both of the respective rates can clearly be identified with a significant portion of salaries and wages of the project. For purposes of this provision, significant is defined as approximately 25% or more of the total costs and a project's total salary and wage costs exceed $250,000. OTHER SPECIAL RATES These rates apply only to the facility or program to which they are idetified. If any additional special rates become necessary the establishment of such ratee should be coordinated through the cognizant negotiation agency. The following fringe benefits are treated as direct casts: OASDI, DICk, RET!RBT PLAN, }LTH/DENTAL/OPTlCAL/LIFE INSCE, WORKERS COMPENSATrO, UNEMPLOYMENT INSURANCE, NON-INDUSTRIAL DISABILITY INSCE, ANNUITANT HEALTH/DENTAL INSURANCE, INCENTIVE AWARD PROGRAM, EMPL'()YEE SUPPORT PROGRAM, SEVERANCE PAY Alm TUITION/FEEl REMISSION OF CERTAIN STUDENT EMPLOYEES. (2 )

JUN-04-2004 15:18 UCOP 510 839 0856 P.05/10 INSTITUTION: University of California (UCSD) San Diego Campus EEMENT DATE: May 28, 2004 SSCTIO III, 02NaRAL A. LIMITATIONS, The rae& in 1. Agreenent are aubjec to any statutory or administrative limitacioda Lnd apply to & given grant, contract or other agreement only to the extent that funds ere available. Acceptance of the rates is subject to the following conditions: (ll Only coats incurred by the organization were included in ita facilities and administrative cost poola.. finally accepted: such costs are legal obligations of the organization and are allowable under the governing cost principles, (2) The aa costt that have been treated as facilities and.iniscracive costs are not claimed AI direct coses; ell Similar types ot costs have been accorded consistent accounting treatment; and (4) rna nformation provided by the or9nlzat1on which was used to establish the rates is no later found to be materially incomplete or inaccurate by the eder.l Government. In such lituac10ns the racers) wculd be 8ject to renegotiation at the discretion 0: the Federal Government. B. ACCOUN":'lNO CHANGESI This reemet 18 baaed on the accounting system purported by the organization to be in effect during the Agreeent period. Changes to the method of.ccounir.g for costs h1ch affect the amount ot reimbursement resuating trom the use of this Agreemen: require prior approval ot the authorized representative o! the c09nizt agency. Such changes include, but are net limited to, changes in the charging or a particular type of cost trom facilities and administrative to direct. Failure to obtain approval may result in cost disallowances. C. F1XED RATBS: It a tixed rate is in this Agreement, it i8 based on a estimate of the COGts for the period covered by the rate. When tbe actl costs for this period are determined, an adjustment will be ade to a rate of a future yeares) to compenlate for the difference beteen the costs used to establish the fixed race and aceual costs. O. USE BY OTHER FEDEItAL AGENCIES, The rates in this Agreement were approved in accordance with the authority in Office of Management a.d Budget Circular A l Circular, and should be applied to grants, contracts and other agreements covered by this Circular, subject to any limit.tion. 1n A above Tne organizac1on may provide copies of the Aeement to other Federal AgenCies to give them early notitication of the "'lement. B'i THE INSTITUTION: University of california (UCSO) San Diego campus (INST!TI.T.l"IO) ON BEl!ALF OF TIlE FEDERAl. GOVEXNHENT: DEPARTMENT OF HEALTH,t..N!) HID'AN SERVICES (SIGNATUXE) ename) (SI GNJlTUR.E ) David S. Low (NA:'IE) (TITLE) O!RECTOR, DIVISION OF COST ALLOCATION (TITLS) (DATE) Hay 28, 2004 (DA'l'S) 0236 R1IS RSPRESSo.'rrA'l'IVE, Robert s. Klein Telephone: (415) 437-7820 (3 )

UNIVERSITY OF CAUFORNIA, SAN DIEGO PREDETERMINED FACILmES AND ADMINISTRATIVE RATES FOR THE PERIOD JULY 1. 2002 THROUGH JUNE 30. 2004 ORGANIZED RESEARCH INSTRUCTION OTHER SOH. ACTlvmf;S MIMITZ MARI EACII..!:2E. Llti. RES. CTR, EXHIBIT A PAGE' ON- OFF- ON- OFF- ON- OFF- ON- OFF-... CAMPUS CAMPUS CAMPUS CAMPUS AMPUS P!.!S CAMPUS ('-AUPII!J1 BUILDING DEP. 3.1% 2.0% 1.5% 0.0% 0.0%... UJ INTEREST 2.7% 0.5% 0.5% 0.0% 0.0% EUIPMENT DEP. 3.6% 3.0% 5.0% 0.0% 0.0% OPERATIONS & MAlNT. 13.6% 10.6% 6.5% 0.0% 0.5% LIBRARY 3.0% 10.9% 2.0C'A. 0.0% 0.0% GENERAL ADMIN. 6.5% 6.5% 9.80/. 8.5% 13.2%. I DEPARTMENTAL ADMIN 16.9% 13.9% 10.0% 3.9% 10.0% c SPON. PR.ADMIN. 2.6% 2.8% 2.9% 2.6% 2.8% n STUDENT SERVICES 0.8% 6.8% 1.8% 0.0% 0.0% o "(I ADMIN. COMPONENTS 26.B% 26.0% 26.00"" 30.0% 28.0% 26.0% 24.5% 24.50/0 24.5% 13.0% 26.0% 26.0% TOTAL 52.0% 26.0% 53.0% 26.0% 40.0% 24.5% 13.0% 28.5 <-t C Z I rt is) CONCUR: (SIGNATURE) TITLE DATE!J1... El I.D UJ!J1 ()'I LJ...

UNIVERSITY OF CALIFORNIA, SAN DIEGO EXHIBIT, PAGE PREDETERMINED FACll..mES AND ADMIft".. MTIVE RATES FOR THE PERIOD JULY 1, 2002 THROUGH JUNE 30, 2004 (DOD CONTRACTS ONLy) ORGANIZED RESEARCH INSTRUCTION OTHER SPON. ACTIVITIES NIMITZ MARINE FACI. GEN. CLIN. RES. CIR. '-t C Z d,.p..p. ON- OFF- ON- OFF ON- OFF- ON- OFF- CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS AMPUS CAMPUS CAMPUS Ul BUILDING DEP. 3.1 D Io 2.0% 1.5% 0.0% 0.0% INTEREST 2.70/0 0.5% 0.5% 0.0% 0.0% \.D EUIPMENT DEP. 3.6% 3.0% 5.0% 0.0% 0.0% OPERATIONS & MAiNT. 13.60/. 10.6% 6.5% 0.0% 0.5% UBRARY 3.0% 10.9% 2.0% 0.0% 0.0% GENERAl ADMIN. 6.5% 6.5% 9.8% 6.5% 13.2% DEPARTMENTAl ADMIN 16.9% 13.9% 10.0% 3.9% 10.0% SPaN. PR. ADMIN. 2.6% 2.8% 2.9% 2.6% 2.8% R STUDENT SERVICES 0.6% 6.8% 1.8% 0.0% 0.0% o -u ADMIN. COMPONENTS 26.8% 26.8"10 26.8% 30.0% 30.0% 30.0% 24.5% 24.5% 24.5% 13.0% 26.0% 26.0% TOTAL ---._--- - --- 52.8% 26.8"10 57.0% 30.0% 40.0% 24.5% 13..1)% 26.5% --- CONCUR: (SIGNATURE) TITLE DATE U1 p (.oj \.D U1 (T'l LJ -J "...

UNIVERSITY OF CAUFORNIA. SAN DIEGO EXHIBIT A L.f PAGE 3 C PREDETERMINED FACILmES AND ADMINISTRATIVE RATES FOR THE PERIOD Z I c;;) JULY 1, 2004 THROUGH JUNE 30, 2005 lsi (SI ORGANIZED RESEARCH INSTRUCTION OTHER SPON. ACTIVITIES NIMITZ MARINE FACIL. GEN. CLIN. RES. etr. I ON OFF- ON- OFF- ON- OFF- ON- OFF-...,. CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS! (J1....,. w BUILDING DEP. 5.0% 4.0% 3.0% 0.0% 4.0% INTEREST 4.0% 3.0% 1.0% 0.0% 0.0% euipment DEP. 3.5% 2.0% 2.0% 0.0% 0.0% OPERATIONS & MAJNT. 13.0% 6.0% 11.5% 0.0% 5.0% LIBRARY 2.0% 12.0% 1.5% 0.0% 0.0% GENERAL ADMIN. 6.5% 7.0% 7.0% 5.5% 9.0%. DEPARTMENTAL ADMIN 16.8% 16.0% 16.0% 10.5% 7.00/. c SPON. PR. ADMIN. 2.6% 1.0% 3.0% 0.0% 3.0% (J STUDENT SERVICES 0.1% 2.0% 0.0% 0.0% 0.0% D ADMIN. COMPONENTS 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 16.0% 19.0% 19.0%.1rul.% TOTAL 53.5%_26.0% 53.0% 26.0% 45.0% Z6.0% 16.0% 28.0% 19.0% - ----... CONCUR: (SIGNATIJRE) TITlE OATE!J1...,. W W c;;) III (Jl 01... " (SI -,it

UNIVERSITY OF CALIFORNIA. SAN DIEGO PREDETERMINED FACILITIES AND ADMINISTRATIVE RATES FOR THE PERIOD EXHIBIT A PAGE 4 JULY 1,2005 THROUGH JUNE 3D, 2006.!>. rij (Sj (Sj ORGANORESEARCH INSTRUCTION OTHER SPON, AC11V1TIES HIMITZ MARINE FACIL. GEN. CLIN. RES. CTR..!>. ON- OFF- ON- OFF- ON- OFF- ON OFF,...,.. CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS U1 BUILDING DEP. 5.0% 4.0% 3.0% 0.0% 4.0%,...,.. ill INTEREST 4.5"10 3.0% 1.0% 0.0% 0.0% EUIPMENTDEP. 3.5% 2.0% 2.0% 0.0% 0.0% OPERATIONS & MAINT. 13.0% S.O% 11.5% 0.0% 5.0% LIBRARY 2.0% 12.0% 1.5% 0.0% 0.0% GENERAL ADMIN. 6.5% 7.0% 7.0% 5.5% 9.0% - DEPARTMENTAl ADMIN 16.8% 16.0% 16.0% 10.5% 7.0% SPON. PR. ADMIN. 2.6% 1.0% 3.0% 0.0% 3.0% c (') STUDENT SERVICES 0.1% 2.0% 0.0% 0.0% 0.0% o 'D ADMIN. COMPONENTS 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 16.0% 19.0% 19.0% 19.0% TOTAL 1-- 54.0% 26.0% 53.0% 26.0% 45.0% 26.0% 16.00/0 28.0% 19.0% - '-i Z J CONCUR: (SIGNATURE) TITLE DATE U1,...,.. W ill U1 en Ll ill,...,.. "

BUILDING DEP. INTEREST euipment DEP. OPERATIONS & MAINT. UBRARY GENERAL ADMIN. OEPARlMENTALADMIN SPON. PR. ADMIN. STUDENT SERVICES ADMIN. COMPONENTS UNIVERSITY OF CAlIFORNIA, SAN DIEGO PREDETERMINED FAClunE5 AND ADMINISTRATIVE RATES FOR THE PERIOD JULY 1, 2006 THROUGH JUNE 30, 2008 ORGANIZED RESEARC H INSTRUCTION OTHER SPON. ACTIVITIES NIMITZ MARltiE FAClh, ON OFF ON OFF ON OFF AMPUS CAMPUS CAMPUS CAMPUS CAMPUS CAMPUS 5.0% 4.0% 3.0% 0.0% 5.0% 3.0% 1.0% 0.0% 3.SOk 2.0% 2.0% 0.0% 13.0% 6.0% 11.5% 0.0% 2.0% 12.0% 1.5% 0.0% 6.5% 7.0% 7.0% 5.5% 16.8% 16.0% 16.0% 10.5% 2.6% 1.0% 3.0% 0.0% 0.1% 2.0% 0.0% 0.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 26.0% 16.0% EXHIBIT A PAGES GEN. CLIN. RES. em. ON OFF CAMPUS CAMPUS' 4.0% 0.0% 0.0% 5.0% 0.0% 9.0%. 7.0%. 3.0% 0.0% 19.0% 19.0% 19.0% y c Z I.t>. r0 lsi.t>. VI ill c n. o -0 TOTAL 54.5% 26.0% 53.0% 26.0% 45.0% 26.0% 16.0% 28.0% 19,!}% CONCUR: -------- (SIGNATURE) TITLE -I o -I f!2 '"0... (SJ DATE tjl... IS IT V. u: IS IT U a '1 I l e

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