EMR Surveillance Intervenes to Reduce Risk Adjusted Mortality March 2, 2016 Katherine Walsh, MS, DrPH, RN, NEA-BC Vice President of Operations,

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EMR Surveillance Intervenes to Reduce Risk Adjusted Mortality March 2, 2016 Katherine Walsh, MS, DrPH, RN, NEA-BC Vice President of Operations, Houston Methodist Hospital Michael Rothman, PhD, Chief Science Officer, PeraHealth

Conflict of Interest Katherine E. Walsh, MS, DrPH, RN, NEA-BC Has no real or apparent conflicts of interest to report.

Conflict of Interest Michael Rothman, PhD Salary: PeraHealth Ownership Interest: Equity owner in PeraHealth

Agenda Origins and Development of an Early Warning System (EWS) Science behind one EWS Potential Applications of the EWS Implementation at Houston Methodist Hospital Clinical Outcomes Next Steps

Learning Objectives Analyze existing EMR data, including vital signs, labs and nursing assessments, to identify patient deterioration and identify actions to reduce adverse outcomes Create consistent communication mechanisms to obviate handoff lapses and manage patient care over the course of multiple shifts Develop and formalize surveillance protocols to assure patients get appropriate attention and care Describe implementation practices to maximize the utilization of the data

An Introduction of How Benefits Were Realized for the Value of Health IT Value Steps Implemented Were: Satisfaction -Precise risk scoring alerts prevent alarm fatigue -Nurse satisfaction is improved as data empowers them to take actions to keep patients safe Treatment/Clinical -EWS utilization improved responsiveness and reduced mortality -EWS provided early interventions by Nurse Practitioner team Electronic Information/Data -EWS derives the full potential of data -Complex algorithm creates output that is user friendly, real time and trended over time http://www.himss.org/valuesuite

Origin of the Rothman Index (RI) Our measure of success has always been preventing what happened to my mother from happening to one other person. Family photo of Michael Rothman used with permission

Science the Heart of the Model Nursing Assessments Estimating Risk All on a Common Scale

Nursing Assessments Simplified Head-to-toe assessments - part of standard nursing school curricula Simplified charting by exception the patient has either met or not met a minimum standard GI standard - Abdomen soft and non-tender. Bowel sounds present. No nausea or vomiting. Continent. Nursing assessments are recorded twice each day Every hospital records essentially the same data

Nursing Assessment Data for the Study 42,302 patient visits from two 1-year periods at an 805-bed community hospital Excluded data from patients under age 18, as well as psychiatric and maternity

Nursing Assessments In-hospital Mortality 10 8 6 4 2 0 Odds Ratios First Assessment 9.4 8.1 7 6.9 6.7 5.6 5.2 3.9 3 2.8 2.3 1.1

Nursing Assessments 1-Year Mortality Nursing Assessment 1-Year Odds Ratio Food 6.7 Neurological 6.5 Psychosocial 5.3 Cardiac 2.3 Pain 0.8 All p-values < 0.001, except for pain, with a p-value of 0.474

Nursing Assessments Clinical Implications If the first nursing assessments taken upon admission correlate with in-hospital mortality and The last nursing assessments taken prior to discharge correlate with post-discharge mortality then It is reasonable to infer that all nursing assessments gathered throughout the patient s stay contain significant clinical information Clinical Implications and Validity of Nursing Assessments: A Longitudinal Measure of Patient Condition from Analysis of the Electronic Medical Record Michael J. Rothman, Alan B. Solinger, Steven I. Rothman, G. Duncan Finlay, BMJ Open 2(4) 2012.

Science the Heart of the Model Nursing Assessments Estimating Risk All on a Common Scale

Delta 1st_year Mortality Estimating Risk Population Norms Creatinine Transform (caps... Low end <.37 then TR=.2, high end > 2.5 then TR=.3) 50% 45% 40% 35% 30% 25% 20% 15% 10% 5% 0% -5% 0 0.5 1 1.5 2 2.5 3-10% act-base calc

Delta 1-Year Mortality Estimating Risk Expert Opinion Heart Rate Transform 80% 70% 60% 50% 40% 30% Delta - act Delta - calc MEWS 20% 10% 0% -10% 0 20 40 60 80 100 120 140 160 BPM Placing clinical variables on a common linear scale of empirically-based risk as a step toward construction of a general patient acuity score from the Electronic Health Record: A modeling study Steven I. Rothman, Michael J. Rothman, Alan B. Solinger, BMJ Open 3(5) 2013.

Delta 1st-Year Mortality Estimating Risk Underlying Physiology Drop in Hemoglobin saturation from 100% to 85% results in a critical fall in po 2 from 120 mmhg to 60 mmhg and corresponds to a sharp rise in excess risk Pulse Ox Transform 70% 60% 50% 40% 30% act-base calc 20% 10% 0% 55 60 65 70 75 80 85 90 95 100-10% Guyton and Hall Textbook of Medical Physiology, 12 th Edition, 2010

Science the Heart of the Model Nursing Assessments Estimating Risk All on a Common Scale

A Common Scale Rothman Index Core Variables Vital Signs Nursing Assessments (Head-to-Toe) Nursing Assessments (Other) Laboratory Tests (blood) Cardiac Rhythm Temperature Cardiac Braden Score Creatinine Asystole Diastolic Blood Pressure Systolic Blood Pressure Respiratory Sodium Sinus rhythm Gastrointestinal Chloride Sinus bradycardia Pulse Oximetry Genitourinary Potassium Sinus tachycardia Respiration Rate Neurological BUN Atrial fibrillation Heart Rate Skin WBC Atrial flutter Safety Hemoglobin Heart block Peripheral Vascular Food/Nutrition Psychosocial Junction rhythm Paced Ventricular fibrillation Musculoskeletal Ventricular tachycardia

A Common Scale Sum Risk Across the Set Development and validation of a continuous measure of patient condition using the Electronic Medical Record, Michael J. Rothman, Steven I. Rothman, Joseph Beals IV. Journal of Biomedical Informatics, 2013 Oct;46(5):837 48.

Rothman Index Validation 48-hour Mortality or Discharge to Hospice Percent Mortality or Discharge to Hospice

Use of RI as an Early Warning System RI model has been published in peer-reviewed literature The hospital software is commercially available on a subscription basis The RI is available for researchers without fee

Implementation at Houston Methodist Hospital History of starts and stops Used selectively for post event review Renewed interest in 2014 Began as nurse driven initiative with interdisciplinary quality steering committee (July 2014) Selected 11 pilot units Partnered with vendor of selected EWS Staff education and champion support Leader driven Change management through stories and data Daily communications on utilization Brought physicians in later

Utilizing the RI as an Early Warning System Graphically present a patient s condition over time using the Rothman Index score. The RI integrates with EHR systems to automate data inputs and visualization The color coded background indicates the RI ranges and adjusts based on rules

Implementation at Houston Methodist Hospital Leveraged the impact of visible data EWS reviewed by nurse five times per 24 hour period Bedside handoff at change of shift (in the morning and evening) Care Coordination Rounds Mid-shift (for day and night shift)

Implementation at Houston Methodist Hospital Escalation algorithms implemented Call Clinical Emergency Response Team Call Physician Administer medication, O2, treatments Increased surveillance-vs, labs, assessments Built momentum through stories and outcomes Reported outcomes to Quality Committee of the Board of Trustees, System Quality Council and various nursing and medical staff forums 7 additional units implemented in July 2015 Phase 3, November 2015, remaining units implemented Nurse Practitioner oversight implemented

Clinical Outcomes Jan 2014 - Jun 2015 (9 months pre-ri, 9 months post-ri) Mortality Rate 30% decrease in mortality rate (1.34% to 0.93%) in original 11 units before and after implementation Mortality Index 32% lower mortality index (0.70 to 0.48) in original 11 units before and after implementation Sepsis Mortality Index 8% lower sepsis mortality index (0.77 vs 0.84) when compared to non- Rothman units

Risk-Adjusted Mortality Index Risk-Adjusted Mortality Outcomes Risk-adjusted mortality decreased 32% on 11 units after RI implementation (0.70 to 0.48), p-value<0.001 1.00 0.90 0.80 0.70 0.60 RI Implementation Process Began 0.70 0.71 0.70 0.73 Non-RI units were unchanged over the same period Study analyzed 33,797 encounters 0.62 0.50 0.49 0.44 0.49 0.40 0.30 0.20 0.10 0.00 2014 Q1-Q3 2014 Q4 2015 Q1 2015 Q2 Rothman Units Non Rothman Units HMH DataMart, Prepared by HMH Service Line Analytics (pt)

Clinical Outcomes Nurse Practitioner Oversight PROCESS Nurse Practitioners reviewing Swim Lanes each night OUTCOME Over 2,500 patients identified at risk (6 months) 5% of time RN/M.D. not aware of decline (132 patients) Nurse Practitioners assessed each risk patient 4 patients were were immediately coded 10% required further intervention (266 patients)

77 Lives Saved over 9 months in 11 Rothman units Image used under license from Shutterstock.com

Potential Applications Patient Assignments Level of Care Decisions Transfer from ICU to acute care Transfer to post acute care Discharge home Code and Emergency Response Review Auto page to Physicians/NP Post Event Review Patient and Family Education End of Life Decision Making Patient Risk Models

A Summary of How Benefits Were Realized for the Value of Health IT Satisfaction -Nurses highly satisfied, confident and engaged in outcomes Treatment/Clinical -Reduction in mortality and mortality index before and after http://www.himss.org/valuesuite

Questions Katherine Walsh, MS, DrPH, RN, NEA-BC kewalsh@houstonmethodist.org Michael Rothman, PhD mrothman@perahealth.com