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1 Page 1 of 8 Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Table Published: February 1, 2010 This table displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH). At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process, implemented in 2008 through the Research, Condition, and Disease Categorization (RCDC) system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH s best estimates based on the category definitions. The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research. Consistent with the Administration s emphasis on transparency, a separate column has been added to distinguish FY 2009 actual support funded from American Recovery & Reinvestment Act (ARRA) accounts from projects funded by regular NIH appropriations. FY 2010 estimates for ARRA reflect only follow-on commitments related to grants awarded in FY The FY 2006 data was produced from a reporting process historically used by NIH. The technical elements of the previous reporting process did not have the ability to produce uniform results and led to wide variability in the way research categories were coded. This process caused inconsistencies in reporting data. RCDC use of data mining improves the consistency and eliminates the wide variability in defining the research categories reported. The table shows FY 2007 through FY 2009 levels produced with the new RCDC methodology and FY estimates based on RCDC actual data. Total Number of Research/Disease Areas: 218 Research/Disease Areas (Dollars in millions and rounded) FY 2006 FY 2007 NIH Historical Method 12/ FY 2007 NIH Revised Method 12/ FY 2008 FY 2009 (Non-ARRA) FY 2009 (ARRA) 13/ FY 2010 Estimated (Non- ARRA) FY 2010 Estimated (ARRA) 14/ FY 2011 Estimated Acute Respiratory Distress Syndrome $74 $48 $87 $82 $103 $17 $106 $9 $109 Agent Orange & Dioxin $17 $18 $15 $13 $13 $2 $14 - $14 Aging $2,431 $2,462 $1,879 $1,965 $3,015 $554 $3,093 $363 $3,172 Alcoholism $511 $521 $443 $452 $441 $75 $452 $48 $467 Allergic Rhinitis (Hay Fever) $4 $5 $7 $6 $4 $1 $4 $1 $4 ALS $44 $39 $40 $43 $43 $13 $44 $11 $45 Alzheimer's Disease $643 $645 $411 $412 $457 $77 $469 $58 $480 American Indians / Alaska Natives $155 $141 $159 $142 $169 $19 $173 $6 $177 Anorexia $15 $12 $8 $7 $8 $2 $8 $2 $8 Anthrax $150 $105 $160 $134 $102 $13 $105 $10 $108 Antimicrobial Resistance $221 $269 $209 $228 $251 $52 $257 $24 $265 Aphasia $15 $14 $20 $22 $22 $3 $22 $1 $23 Arctic $17 $19 $25 $22 $28 $6 $29 $1 $29 Arthritis $355 $339 $222 $232 $246 $65 $252 $35 $259 Assistive Technology $182 $184 $192 $215 $249 $43 $256 $26 $262

2 Page 2 of 8 Asthma $283 $294 $252 $246 $284 $51 $292 $27 $300 Ataxia Telangiectasia $9 $11 $14 $13 $13 $2 $13 $1 $13 Atherosclerosis $337 $347 $468 $460 $495 $112 $508 $91 $522 Attention Deficit Disorder (ADD) $116 $107 $61 $60 $71 $13 $73 $10 $75 Autism $108 $127 $93 $118 $132 $64 $136 $52 $143 Autoimmune Disease $598 $587 $759 $762 $879 $138 $899 $83 $923 Basic Behavioral and Social Science $1,062 $1,104 $1,119 $1,149 $1,410 $206 $1,447 $129 $1,490 Batten Disease $8 $8 $5 $5 $5 $2 $5 $1 $6 Behavioral and Social Science $3,001 $3,060 $3,157 $3,215 $3,471 $582 $3,562 $401 $3,668 Biodefense 1/ $1,766 $1,735 $1,735 $1,736 $1,755 $213 $1,794 $96 $1,853 Bioengineering $1,546 $1,469 $2,610 $2,853 $3,155 $569 $3,229 $318 $3,318 Biotechnology $9,974 $9,814 $5,344 $5,179 $5,619 $1,051 $5,750 $580 $5,911 Brain Cancer $178 $193 $204 $194 $234 $42 $240 $22 $248 Brain Disorders $4,732 $4,670 $3,592 $3,729 $3,538 $685 $3,630 $450 $3,733 Breast Cancer $718 $707 $729 $726 $722 $111 $741 $47 $765 Burden of Illness $508 $524 $60 $48 $43 $11 $44 $6 $46 Cancer $5,575 $5,643 $5,549 $5,570 $5,629 $1,120 $5,781 $346 $6,036 Cardiovascular $2,349 $2,370 $1,942 $2,027 $2,008 $396 $2,058 $298 $2,115 Cerebral Palsy $18 $16 $30 $28 $21 $4 $22 $2 $22 Cervical Cancer $97 $96 $67 $69 $84 $15 $86 $8 $89 Charcot-Marie-Tooth Disease $7 $7 $9 $12 $14 $2 $15 $1 $15 Child Abuse and Neglect Research $38 $38 $41 $30 $32 $5 $33 $4 $34 Childhood Leukemia $53 $55 $50 $39 $47 $12 $48 $9 $50 Chronic Fatigue Syndrome $5 $4 $4 $4 $5 - $5 - $5 Chronic Liver Disease and Cirrhosis Chronic Obstructive Pulmonary Disease $408 $379 $253 $241 $274 $37 $280 $25 $287 $67 $91 $72 $75 $96 $18 $98 $14 $101 Climate Change $50 $47 $4 $4 $4 $2 $5 $2 $5 Clinical Research $8,785 $9,116 $9,862 $9,629 $10,336 $1,854 $10,617 $921 $10,931 Clinical Trials $2,767 $2,949 $3,422 $3,562 $2,966 $485 $3,041 $190 $3,132 Colo-Rectal Cancer $269 $282 $273 $274 $281 $48 $288 $20 $297 Comparative Effectiveness Research Complementary and Alternative Medicine Conditions affecting unborn children + - ** + $194 $246 $199 $162 $205 $301 $299 $426 $430 $513 $70 $526 $43 $541 $103 $110 $81 $81 $95 $8 $97 $4 $100 Contraception/Reproduction $335 $314 $460 $473 $427 $65 $437 $31 $449 Cooley's Anemia $42 $34 $22 $22 $21 $3 $22 $3 $22

3 Page 3 of 8 Cost Effectiveness Research $143 $155 $50 $49 $52 $16 $53 $14 $55 Crohn's Disease $64 $69 $47 $51 $55 $14 $56 $9 $58 Cystic Fibrosis $85 $82 $78 $90 $86 $13 $88 $9 $90 Dental/Oral and Craniofacial Disease $413 $417 $484 $463 $490 $75 $503 $56 $515 Depression $335 $345 $398 $402 $402 $48 $413 $20 $426 Diabetes 2/ $1,038 $1,037 $1,069 $1,080 $1,030 $121 $1,052 $63 $1,078 Diagnostic Radiology $712 $694 $1,046 $1,095 $976 $206 $1,000 $134 $1,027 Diethylstilbestrol (DES) $8 $6 $5 $4 $4 $1 $4 - $4 Digestive Diseases $1,252 $1,234 $1,460 $1,426 $1,538 $243 $1,577 $137 $1,623 Digestive Diseases - (Gallbladder) Digestive Diseases - (Peptic Ulcer) $7 $6 $6 $7 $7 $1 $7 - $7 $17 $23 $15 $14 $17 $3 $18 $2 $18 Down Syndrome $14 $16 $16 $17 $18 $4 $19 $3 $19 Drug Abuse (NIDA Only) 3/ $990 $1,001 $1,001 $1,007 $1,040 $135 $1,068 $113 $1,102 Duchenne/ Becker Muscular Dystrophy $18 $23 $23 $22 $27 $6 $28 $4 $29 Dystonia $19 $16 $18 $15 $16 $2 $17 $1 $17 Eating Disorders 4/ + - ** + $26 $5 $27 $3 $27 Emerging Infectious Diseases $1,857 $1,816 $1,733 $2,098 $2,080 $307 $2,129 $143 $2,194 Emphysema $17 $21 $30 $29 $28 $11 $29 $9 $30 Endometriosis $12 $12 $12 $15 $15 $2 $15 $1 $16 Epilepsy $103 $105 $145 $145 $128 $21 $131 $15 $135 Estrogen $153 $164 $283 $245 $235 $34 $241 $17 $248 Eye Disease And Disorders Of Vision Facioscapulohumeral Muscular Dystrophy $705 $714 $800 $796 $862 $129 $933 $61 $956 $2 $4 $3 $3 $3 $2 $4 $1 $4 Fetal Alcohol Syndrome $29 $34 $32 $34 $34 $7 $35 $4 $36 Fibroid Tumors (Uterine) $15 $14 $20 $16 $18 $2 $19 $1 $19 Fibromyalgia $9 $9 $11 $12 $11 $2 $11 - $12 Food Safety $316 $278 $230 $244 $262 $37 $268 $19 $276 Fragile X Syndrome $20 $27 $22 $26 $27 $5 $28 $4 $29 Frontotemporal Dementia (FTD) $33 $31 $17 $17 $22 $2 $22 $1 $23 Gene Therapy $356 $325 $250 $249 $221 $28 $227 $18 $233 Gene Therapy Clinical Trials $32 $31 $12 $16 $11 - $11 - $11 Genetic Testing $417 $395 $402 $383 $316 $76 $324 $53 $334 Genetics $4,878 $4,878 $7,000 $6,872 $7,278 $1,676 $7,459 $792 $7,676 Global Warming Climate Change $58 $56 $1 $1 $3 $1 $3 $1 $3 Health Disparities 5/ $2,766 $2,744 $2,744 $2,614 $2,806 $434 $2,887 - $2,970

4 Page 4 of 8 Health Effects of Climate Change $157 $164 $258 $286 $179 $35 $183 $17 $188 Health Services $929 $1,023 $730 $743 $1,102 $316 $1,131 $190 $1,165 Heart Disease $2,087 $2,126 $1,126 $1,217 $1,202 $227 $1,232 $161 $1,267 Heart Disease - Coronary Heart Disease $398 $382 $379 $367 $426 $98 $437 $70 $450 Hematology $1,114 $1,128 $881 $894 $908 $151 $931 $88 $959 Hepatitis $177 $174 $176 $180 $178 $23 $182 $15 $187 Hepatitis - A $3 $2 $6 $6 $4 - $4 - $5 Hepatitis - B $36 $42 $53 $53 $51 $6 $52 $2 $54 Hepatitis - C $122 $108 $100 $93 $97 $12 $100 $9 $102 HIV/AIDS 6/ $2,902 $2,906 $2,906 $2,928 $3,019 $319 $3,086 - $3,184 Hodgkin's Disease $21 $17 $12 $16 $26 $1 $27 $1 $28 Homelessness $21 $18 $14 $13 $16 $3 $16 $3 $17 Homicide and Legal Interventions HPV and/or Cervical Cancer Vaccines $11 $8 $1 * $2 $1 $2 - $2 $14 $20 $16 $19 $25 $2 $26 $2 $27 Human Fetal Tissue 7/ $23 $19 ** $40 $41 $22 $42 $18 $43 Human Genome $1,065 $1,099 $1,246 $1,259 $1,775 $566 $1,820 $356 $1,875 Huntington's Disease $48 $53 $49 $51 $57 $12 $58 $7 $60 Hyperbaric Oxygen $2 $2 $3 $4 $3 - $4 - $4 Hypertension $395 $390 $231 $263 $266 $41 $272 $29 $280 Immunization $1,438 $1,342 $1,713 $1,734 $1,773 $191 $1,815 $80 $1,870 Infant Mortality/ (LBW) $478 $464 $227 $246 $246 $32 $257 $18 $265 Infectious Diseases $3,132 $3,059 $3,433 $3,575 $3,627 $526 $3,712 $251 $3,822 Infertility $40 $51 $65 $73 $75 $17 $77 $13 $82 Inflammatory Bowel Disease $72 $80 $74 $81 $91 $22 $92 $12 $95 Influenza $207 $271 $280 $204 $316 $46 $327 $13 $337 Injury - Childhood Injuries $28 $27 $28 $26 $33 $3 $34 $2 $35 Injury - Trauma - (Head and Spine) $233 $219 $164 $150 $161 $33 $165 $19 $170 Injury - Traumatic brain injury $85 $82 $73 $59 $71 $15 $73 $8 $75 Injury - Unintentional Childhood Injury Injury (total) Accidents/Adverse Effects $25 $21 $17 $15 $19 $1 $19 - $20 $355 $403 $299 $299 $340 $58 $348 $30 $358 Interstitial Cystitis $25 $23 $10 $10 $11 $1 $12 - $12 Kidney Disease $434 $450 $531 $523 $570 $85 $585 $39 $601 Lead Poisoning $15 $15 $13 $9 $11 $3 $11 - $11 Liver Cancer $88 $90 $103 $89 $94 $12 $96 $7 $99 Liver Disease $450 $423 $589 $562 $572 $79 $587 $48 $603

5 Page 5 of 8 Lung $978 $1,013 $1,169 $1,211 $1,265 $234 $1,297 $142 $1,335 Lung Cancer $266 $249 $164 $169 $178 $36 $183 $20 $188 Lupus $97 $84 $113 $126 $115 $19 $118 $11 $121 Lyme Disease $24 $22 $26 $22 $25 $5 $25 $3 $26 Lymphoma $170 $158 $186 $193 $184 $22 $188 $13 $194 Macular Degeneration $60 $70 $135 $135 $85 $8 $87 $3 $89 Malaria $98 $104 $112 $132 $110 $11 $112 $6 $116 Malaria Vaccine $35 $36 $31 $32 $34 $3 $35 $2 $36 Mental Health $1,824 $1,853 $2,061 $2,086 $2,129 $382 $2,185 $250 $2,252 Mental Retardation (Intellectual and Developmental Disabilities (IDD)) $188 $204 $305 $350 $281 $94 $288 $71 $297 Methamphetamine $45 $45 $66 $67 $69 $13 $70 $13 $72 Mind and Body $136 $133 $571 $567 $494 $90 $507 $75 $521 Minority Health 5/ $2,423 $2,407 $2,407 $2,396 $2,592 $378 $2,667 - $2,743 Mucopolysaccharidoses (MPS) $10 $10 $8 $7 $7 - $7 - $7 Multiple Sclerosis $110 $98 $149 $169 $137 $25 $140 $13 $144 Muscular Dystrophy $40 $47 $58 $56 $66 $17 $68 $10 $70 Myasthenia Gravis $9 $6 $10 $9 $9 $3 $9 - $9 Myotonic Dystrophy $7 $8 $9 $9 $9 $4 $10 $2 $10 Nanotechnology 8/ $192 $215 $257 $304 $343 $73 $361 $42 $382 Networking and Information Technology R&D 8/ $423 $507 $959 $911 $1,174 $168 $1,201 $77 $1,235 Neurodegenerative $1,217 $1,166 $1,579 $1,621 $1,553 $262 $1,593 $169 $1,633 Neurofibromatosis $16 $13 $12 $14 $17 $2 $17 $1 $18 Neuropathy $54 $59 $118 $121 $119 $13 $123 $9 $126 Neurosciences $4,830 $4,809 $5,102 $5,224 $5,320 $848 $5,456 $513 $5,605 Nutrition $1,039 $1,075 $1,327 $1,391 $1,400 $205 $1,435 $108 $1,475 Obesity $594 $661 $595 $664 $745 $117 $763 $68 $784 Organ Transplantation $363 $358 $187 $175 $139 $32 $142 $10 $146 Orphan Drug $1,255 $1,158 $653 $645 $441 $118 $453 $55 $467 Osteogenesis Imperfecta $5 $5 $8 $5 $5 $1 $6 - $6 Osteoporosis $169 $164 $167 $183 $198 $21 $203 $10 $209 Otitis Media $17 $15 $20 $18 $15 $7 $16 $2 $16 Ovarian Cancer $102 $103 $89 $96 $102 $13 $105 $6 $108 Paget's Disease $6 $4 $1 $1 $1 $1 $1 - $1 Pain Conditions - Chronic $220 $224 $277 $279 $333 $53 $341 $31 $350 Parkinson's Disease $208 $187 $143 $152 $162 $24 $166 $16 $171 Pediatric $3,161 $3,173 $2,622 $2,771 $2,996 $505 $3,073 $308 $3,166 Pediatric AIDS 9/ $276 $262 $262 $241 $227 $20 $233 - $241

6 Page 6 of 8 Pediatric Research Initiative $141 $171 ** $209 $214 $256 $219 $205 $226 Pelvic Inflammatory Disease $4 $3 $4 $3 $3 $1 $3 $1 $3 Perinatal - Birth - Preterm (LBW) $374 $351 $181 $197 $177 $23 $181 $15 $186 Perinatal - Neonatal Respiratory Distress Syndrome Perinatal Period - Conditions Originating in Perinatal Period $8 $9 $23 $18 $31 $5 $31 $3 $32 $407 $387 $413 $449 $470 $65 $482 $37 $495 Pick's Disease $1 $1 $3 $2 $2 - $2 - $2 Pneumonia $145 $132 $105 $93 $108 $15 $110 $8 $114 Pneumonia & Influenza $351 $405 $382 $295 $392 $58 $402 $21 $414 Polycystic Kidney Disease $32 $36 $33 $41 $38 $7 $39 $4 $40 Prevention $6,815 $6,729 $4,596 $4,623 $5,332 $844 $5,465 $475 $5,626 Prostate Cancer $348 $345 $295 $290 $310 $47 $319 $26 $329 Psoriasis $8 $10 $22 $8 $13 $3 $13 $2 $14 Regenerative Medicine $614 $575 $697 $723 $799 $144 $818 $90 $841 Rehabilitation $324 $344 $379 $403 $404 $75 $415 $56 $446 Rett Syndrome $5 $6 $6 $9 $9 $4 $10 $2 $10 Reye's Syndrome $1 $1 $0 $ Rural Health $202 $208 $173 $170 $186 $42 $190 $21 $196 Schizophrenia $364 $358 $220 $249 $265 $85 $272 $44 $280 Scleroderma $11 $12 $12 $20 $21 $2 $22 $1 $22 Septicemia $49 $49 $93 $95 $92 $19 $94 $10 $97 Sexually Transmitted Diseases/Herpes $264 $288 $282 $245 $250 $43 $256 $25 $264 Sickle Cell Disease $91 $94 $78 $80 $63 $14 $64 $10 $66 Sleep Research $199 $190 $219 $225 $217 $33 $223 $19 $229 Small Pox $149 $122 $142 $94 $94 $4 $96 $3 $99 Smoking and Health $517 $534 $324 $310 $329 $78 $338 $46 $358 Spina Bifida $11 $9 $14 $15 $14 $3 $14 $2 $14 Spinal Cord Injury $66 $64 $90 $80 $80 $14 $82 $8 $84 Spinal Muscular Atrophy $15 $11 $11 $10 $11 $3 $11 $3 $12 Stem Cell Research $643 $657 $968 $938 $1,044 $187 $1,070 $112 $1,100 Stem Cell Research - Embryonic - Human 10/ Stem Cell Research - Embryonic - Non-Human Stem Cell Research - Nonembryonic - Human Stem Cell Research - Nonembryonic - Non-Human Stem Cell Research - Umbilical Cord Blood/ Placenta $38 $42 $74 $88 $120 $23 $123 $14 $126 $110 $106 $120 $150 $148 $29 $151 $10 $155 $206 $203 $226 $297 $339 $58 $348 $40 $358 $289 $306 $400 $497 $550 $88 $564 $52 $580 $19 $22 $44 $46 $49 $10 $50 $7 $52

7 Page 7 of 8 Stem Cell Research - Umbilical Cord Blood/ Placenta - Human Stem Cell Research - Umbilical Cord Blood/ Placenta - Non- Human $16 $19 $38 $38 $42 $9 $43 $7 $45 $4 $2 $9 $9 $10 $1 $10 - $11 Stroke $342 $340 $288 $296 $329 $54 $338 $35 $347 Substance Abuse 11/ $1,490 $1,523 $1,636 $1,763 $1,653 $245 $1,697 $180 $1,750 Sudden Infant Death Syndrome $77 $81 $25 $29 $22 $6 $22 $2 $23 Suicide $32 $43 $52 $39 $36 $15 $37 $3 $38 Teenage Pregnancy $21 $16 $24 $21 $23 $5 $23 $3 $24 Temporomandibular Muscle/Joint Disorder (TMJD) $17 $15 $18 $19 $15 $1 $15 $1 $15 Tobacco $515 $536 $325 $311 $331 $78 $340 $46 $360 Topical Microbicides $88 $99 $92 $102 $92 $7 $124 $1 $130 Tourette Syndrome $13 $11 $9 $8 $7 $3 $7 - $7 Transmissible Spongiform Encephalopathy (TSE) $35 $43 $50 $44 $43 $4 $44 $1 $46 Transplantation $551 $534 $544 $519 $571 $94 $585 $48 $601 Tuberculosis $150 $166 $188 $142 $189 $27 $195 $14 $199 Tuberculosis Vaccine $22 $17 $23 $18 $15 $3 $15 $2 $16 Tuberous Sclerosis $9 $12 $20 $20 $20 $3 $20 $2 $21 Urologic Diseases $536 $526 $535 $534 $578 $81 $594 $39 $612 Uterine Cancer $28 $22 $24 $16 $25 $4 $26 $3 $27 Vaccine Related $1,449 $1,358 $1,659 $1,632 $1,593 $185 $1,631 $77 $1,680 Vaccine related (AIDS) 9/ $566 $597 $597 $556 $561 $35 $567 - $603 Vector-Borne Diseases $464 $424 $478 $417 $401 $66 $411 $38 $423 Violence Against Women $20 $24 $49 $45 $39 $2 $40 $2 $41 Violence Research $113 $106 $190 $183 $182 $21 $187 $16 $192 Vulvodynia + - ** + $1 $1 $1 $1 $1 West Nile Virus $85 $69 $81 $39 $59 $7 $61 $4 $63 Women's Health 5/ $3,498 $3,470 $3,470 $3,514 $3,725 $506 $3,822 - $3,930 Youth Violence $67 $60 $123 $115 $111 $12 $114 $9 $118 [*] The minimum reporting threshold for a specific disease/condition is $500,000. Reporting of $0 does not indicate that no research is being conducted. [**] No methodology was identified for RCDC in 2007; therefore there is no data available under the FY 2007 column. [+] Indicates a new category. Funding support data not available prior to the actual FY 2009 level reported. 1/ Reporting for this category does not follow the standard RCDC process. The total amount reported is consistent with reporting requirements for this category to the U.S. Office of Management & Budget (OMB). The project listing does not include non-project or other support costs associated with the annual total for this category. Additional information on this category is available at 2/ Includes research funded from the Type 1 diabetes appropriation of $150,000,000. These are project listings only. 3/ Reporting for this category does not follow the standard RCDC process. Spending is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements (Only NIDA). More information on this area is available at 4/ Reported total for this category encompasses research for anorexia, bulimia nervosa, binge eating disorders, and eating disorders not otherwise specified.

8 Page 8 of 8 5/ Reporting for this category does not follow the standard RCDC process. This category assigns project funding according to populations tracked by gender or ethnicity. The databases used to track gender/ethnicity are complex and not currently compatible with the RCDC system. 6/ Reporting for this category does not follow the standard RCDC process. These are project listings only and non-project or other support costs associated with the annual total for the category are not included. More information on this area is available at 7/ Reporting for this category does not follow the standard RCDC process. This category uses a non-standard approach involving subject matter expert reviews of manually collected project listings. 8/ The data provided reflects funding amounts reported by the NIH RCDC process for this category. and estimate levels presented on this site supersede FY amounts detailed in OMB MAX DE application tables that were based on preliminary FY 2009 funding support information. 9/ Reporting for this category does not follow the standard RCDC process. These are project listings only and non-project or other support costs associated with the annual total for the category are not included. More information on the budget associated with the category is available at Research reported for this category is also captured under the broader HIV/AIDS category. 10/ Human embryonic stem cell research projects awarded with restrictions may have been included in the FY2009 report. 11/ Reporting for this category does not follow the standard RCDC process. This category includes all spending reported under the Drug Abuse category as well as projects categorized under the broader area of Substance Abuse. These are project listings only. More information on this area is available at 12/ To illustrate the effect of the RCDC methodology change, the table shows a side-by-side comparison of FY 2007 levels produced with the prior method ( NIH Historical Method ) compared with levels that would have resulted if the new methodology had been implemented ( NIH Revised Method ). NIH Historical Method figures are considered the official for FY The NIH Revised Method levels provide for comparability to FY 2008 RCDC actuals. 13/ A separate column added to distinguish FY 2009 actual support funded from American Recovery & Reinvestment Act (ARRA) accounts from projects funded by regular recurring NIH appropriations. 14/ FY 2010 estimates for ARRA reflect only follow-on commitments related to grants awarded in FY Obligations associated with potential exercise of option years for contracts let in 2009 or new contracts as well as award of new competing grants are not included.