Title: Hair growth-promoting activity of hot water extract of Thuja orientalis

Transcription

1 Author's response to reviews Title: Hair growth-promoting activity of hot water extract of Thuja orientalis Authors: Nan-nan Zhang Dong Ki Park Hye-Jin Park Version: 7 Date: 3 December 2012 Author's response to reviews: see over

2 Reviewer's report Title: Hair promoting activity of a hot water extract of Thuja orientalis Version: 6 Date: 31 October 2012 Dear Dr. Sandhya S We greatly appreciate the efforts of the Editorial Board and reviewers for giving us the valuable comments on our manuscript for publication BMC Complementary and Alternative Medicine. As you requested, we have enclosed a revised version of manuscript in response to the extensive and insightful reviewer comments. Included below is a point-by-point description of our responses to the reviewer s and editor s comments. The revision made in the manuscript was written in blue. Some corrections for language were done as the reviewer suggested. We hope that you and the reviewers find this revised manuscript acceptable for publication in BMC Complementary and Alternative Medicine. Thank you. Yours sincerely, Hye-Jin Park, Ph.D.

3 Reviewer: Sandhya S Reviewer's report: 1. The title of the article can be modified as Hair growth promoting activity of hot water extract of Thuja orientalis. Response: We modified the title as the reviewer suggested. <Before revision> Hair growth promoting activity of a hot water extract of Thuja orientalis <After revision> Hair growth promoting activity of hot water extract of Thuja orientalis 2. It is not necessary to mention a hot water extract of Thuja orientalis every where in the text as it is looking very odd while going through your article. hence once you can mention this in the abstract, then once in the method, and once in the results and discussion part. Response: We changed it as the reviewer commented. Editorial comments: - Upon reassessment of your previous response to the comments of the reviewers, we could not find any response to the points raised by reviewer 2. Could we therefore ask you to ensure that you respond to these comments in some manner. If you do not feel that it is necessary to make changes to your manuscript based upon the comments, please clearly explain your reasoning for this in your point-by-point cover letter. In this case we would still strongly encourage you to address the comments in some manner in your manuscript, perhaps as

4 limitations of your study. Response: We responded the reviewer 2 s comments. It would be better to revise the manuscript as the reviewer2 suggested. We revised the manuscript according to the comments. - Thank you for including an ethics statement in your manuscript. However, we would ask you to confirm that specific approval for the protocols used in your study was granted by the ethics committee of your institution. Please amend your ethics statement so that this is clearly stated. Response: We amended the ethics statement as below. All animal procedures were performed according to the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health as well as the guidelines of the Animal Welfare Act. This experiment was performed in accordance with the institutional guidelines (The Institutional Animal Care and Use Committee (IACUC) at Konkuk University (Seoul, Korea)). The authorization code number from IACUC is ku Please include an Author's Contributions section in your manuscript. Further details on the information that we would ask you to include in this section, as well as formatting guidelines, can be found through the following link: e#formatting-contributions. Response: We included the Authors contributions section in the revised manuscript. Authors contributions

5 NZ carried out the molecular analysis and immunohistochemistry. DKP participated in the design of the study and performed the statistical analysis. HJP carried out the molecular analysis. HJP conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript. - We still feel that further improvements are required in the quality of English used in your manuscript. We recommend that you ask a native English speaking colleague to help you copyedit the paper. If this is not possible, you may need to use a professional language editing service. For authors who wish to have the language in their manuscript edited by a native- English speaker with scientific expertise, BioMed Central recommends Edanz ( BioMed Central has negotiated a 10% discount to the fee charged to BioMed Central authors by Edanz. Use of an editing service is neither a requirement nor a guarantee of acceptance for publication. For more information, see our FAQ on language editing services at Response: We used the editing service from Habisco Co. Ltd for improving the quality of English.