CCTSI SUMMIT III The Road to T3 and T4 Research Funding: David R. West, PhD Dan Holtrop, MA

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1 CCTSI SUMMIT III The Road to T3 and T4 Research Funding: David R. West, PhD Dan Holtrop, MA

2 Who are we today? Experienced researchers with a federal funding track record? AHRQ, NIH, PCORI (quasi-gov), CDC, NSF New researchers getting started without federal funding as PI? Clinicians/Program staff working in communities, wishing to engage in research? New to the field and trying to learn? Other?

3 Key Lessons Be Flexible and Adapt KISS no world peace Be strategic Be serious Have a thick skin Measure success at levels below 30%

4 Examples For Experienced Researchers with a Track Record AHRQ Patient-Centered Outcomes Research Clinical Decision Support Learning Network (U18) RFA-HS Related AHRQ U18 NIMHD Transdisciplinary Collaborative Centers for Health Disparities Research on Chronic Disease Prevention (U54) RFA-MD Related NIMHD U54 Tobacco Regulatory Science Small Grant Program for New Investigators (R03) RFA-OD Related ODP R03

5 PA See Related NIDDK07/31/ /16/ /08/2018 R21 Pilot and Feasibility Clinical and Translational Research Studies in Digestive Diseases and Nutrition (R21) PA See Related NIAID07/28/ /16/ /08/2018 R21 Research to Advance Vaccine Safety (R21) PA See Related AHRQ07/18/ /25/ /26/2017 R18 AHRQ Health Services Research Demonstration and Dissemination Grants (R18)

6 Experienced PCORI Patient-Powered Research Networks (PPRN) Research Demonstration Projects Improving Healthcare Systems Communication and Dissemination Research

7 Play 2 nd fiddle Funding for mortals Foundations: Generally don t like to fund research but do like to fund programs with evaluation components. Be Flexible and Adapt Institutions Including where we work: May wish to/or need to fund research. Examples?? Healthcare Other businesses

8 The CCTSI Can Help Community Engagement Pilot Program: Supports community-academic partnerships to perform pilot studies that will strengthen relationships and produce preliminary data for future competitive grant applications. RFAs and funding are issued annually, with applications due in the fall.($30k - ish)

9 Colorado State University Pilot Program: Provides one-year pilot awards to encourage crossdisciplinary and collaborative clinical-translational research focused on promotion of innovative research collaborations and interactions for clinical and translational research at CSU that will lead to new funded research. The CSU-Pilot Program is a clinical-translational research program for CSU researdhers.awards will be for a maximum of $25,000 (indirect costs not permitted). The CSU-Pilot Program intends to award at least $100,000 this year toward these research goals.

10 Colorado Pilot Program: Provides one-year pilot awards to encourage cross-disciplinary and collaborative research in clinical and translational medicine. Translational research is intentionally broadly defined. RFA issued in July, Applications due in September, Awards begin in January.CO-Pilot Award Categories: Mentored - $30,000 Junior Mentored -$30,000 - $60,000 Independent CSU/CU Collaboration - $60,000 Team Science - $100,000

11 Research Studio Program Take your research project to the next level.

12 What is the Research Studio Program? Dynamic and integrative way of increasing and improving clinical and translational research. Based on research and design models from industry. Engages multi-disciplinary experts. Targeted, structured and collaborative discussion. FREE and funded by the CCTSI!

13 Studio Format 90 minute consultation with three to five handpicked relevant research experts minute investigator presentation minutes of targeted discussion around three or four predetermined questions minute summarizing comments from the moderator and panelists. Investigator is provided with an audio recording of the discussion and a summary of the written comments and notes from the session.

14 Studio Categories of Research T1/T2 Protocols Bench to Bedside (Jane Reusch, MD). Pathophysiology. Mechanisms of disease. Clinical feasibility. Clinical safety. Efficacy trials. T3/T4 Protocols Bedside to practice and policy (David R. West, PHD). Comparative effectiveness. Epidemiology. Health service. Health behavior and education. Implementation science. Community based research. Health policy.

15 Pre-Award Studio Consultations Hypothesis Generation. Develop innovative and well-constructed hypothesis. Study Design. Select and develop appropriate methods and design. Implementation. Execute and monitor projects to achieve the best standards in research. Grant Review. Internal study section to make applications more competitive.

16 Post-Award Studio Consultations Analysis and interpretation. Analyze and interpret study data to develop additional research questions and theories. (Not a full data analysis). Manuscript review. Prepare manuscripts for publication including review of focus, logic, data presentation and identification of appropriate journals. Translation. Understand research implications for application in communities, practice and/or policy.

17 Take Your Research Project to the Next Level! Request a Studio Look for more information and our online link to Request a Studio at: Or contact Dan Holtrop at: daniel.holtrop@ucdenver.edu

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