The types and causes of prescribing errors generated from electronic prescribing systems: a systematic review

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1 The types and causes of prescribing errors generated from electronic prescribing systems: a systematic review Clare L. Brown, Helen L. Mulcaster, Katherine L. Triffitt, Dean F. Sittig, Joan Ash, Katie Reygate, Andrew K. Husband, David W. Bates, Sarah P. Slight.

2 EP & CDS

3 Background to the Review Medication errors are responsible for patient harm Majority of errors occur at the prescribing stage Complex process, susceptible to many different types of error Computerized provider order entry (CPOE) with clinical decision support (CDS) systems can help prevent medication errors, improve patient care and reduce healthcare costs.

4 The problem? These systems have also been associated with new types of error (Ash et al.) Without reflection, we go blindly on our way, creating more unintended consequences, and failing to achieve anything useful - Margaret J. Wheatley

5 Aim: To understand the different types and causes of prescribing errors associated with CPOE systems, and to make recommendations about how these systems could be improved

6 Methods: Systematic Literature Review Inclusion criteria Primary research studies that focused on prescribing errors associated with CPOE containing qualitative data about the types and causes of errors. Information sources and search Searched databases: the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase (OVID) and Medline (OVID). Study selection Titles Abstracts Full Texts Data collection and analysis Data extraction Narrative sysnthesis

7 Included Eligibility Screening Identification Search Results Records identified in the search (n = 1,185) (Medline n=134, Embase n=549, CINAHL n=502) Number of titles screened (n = 1,185) Duplicate articles and Records excluded: (n = 717) Number of abstracts screened (n = 468) Records excluded: (n=319) Full-text articles assessed for eligibility (n = 149) Full-text articles excluded, with reasons: (n = 115) Studies included in qualitative synthesis (n = 34)

8 Results 31 full text articles and 3 conference abstracts. Eight key themes US Computer Screen Display Drop-down Menus and Autopopulation Wording US and Canada Canada UK Australia Spain Sweeden Default Settings Non-intuitive ordering or information transmission Repeat Prescriptions and Automated Processes Denmark Netherlands Users Work Processes CDS Systems

9 1. Computer Screen Display Incomplete list of a patient s medications on the computer screen. Multiple screens, which require users to click through various parts of the CPOE system.. Similarly designed screens or features that have Important functional differences Simple to move between different patients on an electronic system,

10 2. Drop-down menus and Auto-population Selection errors associated with different drop down lists (e.g., patient names, medication names, drug dosages, etc.) Delays in system response time resulted in prescribers using multiple clicks to select a drug item Inadvertent mouse wheeling Auto-population functionality, whereby on entering the first few letters (or numbers) of a drug name (or dose), the system suggests information that could be easily selected in error.

11 3. Wording Confusing wording, User-Design Mismatch Difficulty finding items or knowing the specific wording 4. Default Settings Failure to change a default time presented by the system Lack of knowledge about the default stop dates and times of medications Drugs included in an order set

12 5. Non-Intuitive Ordering or Information Transmission Inflexible ordering processes Entry of unfamiliar abbreviations in free-text boxes, are open to misinterpretation Compatibility issues 6. Repeat Prescriptions and Automated Processes Failure to update the original prescription Reduced visibility of computerised errors.

13 7. Users Work Processes Inappropriate work processes, batch entry Inconvenient log-in process 8. CDS Alerting Alert fatigue Underutilisation of CDS functionality Provided erroneous information

14 Discussion & Conclusion All eight themes relate closely to human factors and user-centred design.

15 Recommendations System designers Organisation: Researchers: and developers: Consistency User Pre and education post-evaluation and training of CPOE and Avoid Introduce CDS ambiguous additional language checks into the Avoid prescribing Further long research lists process. into the types and Tall Use causes man of CDS, of lettering these where systems &/ a clinical indication U.K. need based has Inform been CDS system identified. design and More Pre development and sensitive post-evaluation and specific of user s CDS Improved normal workflow. interoperability

16 Thank you for Listening Any Questions?

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