SCALING-UP COMMUNITY BASED NEONATAL RESUSCITATION IN INDONESIA : A RETROSPECTIVE CASE STUDY. Jennifer Kim Rosenzweig, MPH, MHA

Transcription

1 SCALING-UP COMMUNITY BASED NEONATAL RESUSCITATION IN INDONESIA : A RETROSPECTIVE CASE STUDY Jennifer Kim Rosenzweig, MPH, MHA A dissertation submitted to the faculty of the University of North Carolina at Chapel Hill in partial fulfillment of the requirements for the degree of Doctorate of Public Health in the Department of Health Policy and Management. Chapel Hill 2011 Approved by: Bruce Fried Edward Brookes Margaret Bentley Stephen N. Wall Kirana Pritasari

2 2011 Jennifer Kim Rosenzweig, MPH, MHA ALL RIGHTS RESERVED ii

3 ABSTRACT JENNIFER KIM ROSENZWEIG: Scaling-Up Community Based Neonatal Resuscitation in Indonesia : A Retrospective Case Study (Under the direction of Bruce Fried) Achieving millennium development goal 4 (the reduction of child mortality by two-thirds by 2015) does not require new science and technology. Rather, it demands the expansion and implementation of evidenced based practices throughout Indonesia to reach the large and diverse population of 237 million persons. This retrospective case study examines how community based neonatal resuscitation was piloted, and scaled up in Indonesia from , with the intent of informing the design, and implementation of future government, and donor programs aimed at scaling up evidenced based health innovations in low resource settings. The study concludes with a revised framework for planning, reviewing, and evaluating scale up of evidence based practices. Recommendations are provided to the Ministry of Health, provincial and district health authorities, and international organizations for the future design, implementation, monitoring and evaluation of scale up programs and initiatives. iii

4 DEDICATION I dedicate this dissertation research to; our son Zachary Sage Emil Petkovich, who died as a result of birth asphyxia on November 12, 2005; all Indonesian families who have lost a child to birth asphyxia, and to all Indonesian Midwives who fight every day to save the lives of mothers and newborns. iv

5 AKNOWLDGEMENTS Completion of this dissertation and the doctorate program would not have been possible without the tremendous amount of guidance and support I have received from so many. My dissertation committee has provided valuable feedback, and encouragement throughout the conceptualization and writing of this dissertation. Thank you to; Bruce Fried, my committee chair, for his overall guidance, and thoughtful comments; Ned Brookes for his continual encouragement, and ensuring that my work met the criteria of the doctoral program; Peggy Bentley for her advice on methodology, and her global health perspective; Steve Wall, for taking the time outside his many commitments to Saving Newborn Lives to ensure the theoretical approach remained embedded in programmatic experience; and Dr. Kirana Pritasari, for ensuring that the design of the study, and resulting framework are relevant for the Ministry of Health of Indonesia. Thank you to the senior management, and my fellow staff of Save the Children Indonesia for allowing me the time and flexibility to complete this research and doctorate program. The support and assistance of the Provincial Health Office of West Java, and the District Health Offices of Cirebon has been essential in providing access to critical data and providing logistic support for interviews. v

6 To my fellow doctorate program cohort members, thank you for sharing your professional experiences and insight over these past three years. You have each greatly enriched my learning. To all interview participants, thank you for willingness to spend time reflecting on your work and experiences. Your insights have been invaluable. Finally, the completion of this program would not have been possible without the continued support from my family. To my parents, Ellen and Larry, and my mother-in-law Kay, thank you for your never ending encouragement, support and inspiration to continue to strive towards higher levels of achievement. To my husband, thank you for your patience and support throughout three years of weekends, and very early morning study and writing sessions. vi

7 TABLE OF CONTENTS LIST OF TABLES..ix LIST OF FIGURES...x LIST OF ABBREVIATIONS.xi Chapter I. Background and Justification.1 Section 1: Introduction... 1 Section 2: Problem Statement 2 Section 3: The Indonesian Context 3 Section 4: Research Study Aims 7 II. Literature Review...9 Section 1: Background...9 Section 2: Methodology...10 Section 3: Results.12 Section 4: Discussion and Recommendations..30 III. Conceptual Framework and Methodology..33 Section 1: WHO/Expandnet Scale Up Framework..33 Section 2: Research Questions.36 Section 3: Study Design...40 IV. Case Study of the Introduction of Community Based Neonatal Resuscitation to Indonesia 54 Section 1: Introduction.54 Section 2: Story of Cirebon..56 Section 3: Scale Up Framework Analysis 81 Section 4: Discussion and Conclusion V. Subang Case Study.103 Section 1: Story of Subang Experience..104 Section 2: Scale-up Framework Analysis Section 3: Discussion and Conclusions..130

8 VI. Discussion and Recommendations.133 Section 1: Synthesis of Case Studies.134 Section 2: Limitations of Research 141 Section 3: Proposed Revised Framework Section 4: Recommendations.155 APPENDIX REFERENCES

9 LIST OF TABLES Table 3.1 Cirebon Demographics Subang Demographics Cirebon Ranking of Puskesmas Subang Ranking of Puskesmas Cirebon Selected Sub-district Profile Subang Selected Sub-District Profile Data Source per Research Question Cirebon District Maternal and Newborn Health Report Selected Sub-district Profile Karrangsembung Neonatal Mortality Data Number of Trained Midwives Subang Neonatal Mortality Subang Sub-District data for Palasari and Ciasem ix

10 LIST OF FIGURES Figures 1.1 Indonesia Under-five Mortality Data Contribution to Under-five Mortality Expandnet/WHO Scale-up Framework Expandnet/Who Scale-up Framework Pre-selected Resuscitation Devices Expandnet/WHO Scale-up Framework Proposed Framework Phase 1 Proposed Framework Phase 2 Proposed Framework Phase 3 Proposed Framework Phase 4 Proposed Framework Phase 5 Proposed Framework x

11 LIST OF ABBREVIATIONS AusAID CHW DHO IMR MDG MNH NMR PATH PHO SBA SC SNL TBA USAID UNICEF WHO Australian Agency for International Development Community Health Worker District Health Office Infant Mortality Rate Millennium Development Goal Maternal Newborn Health Neonatal mortality rate Partnership for Appropriate Technology for Health Provincial Health Office Skilled birth attendance Save the Children Saving Newborn Lives Traditional Birth Attendant United States Agency for International Development United Nations Child Fund World Health Organization xi

12 Chapter 1: Background and Justification Section 1: Introduction The major gap for saving the lives of mothers and babies in not new science, but implementation science better understanding of how to deliver effective care, and reach the poorest families with high impact interventions (J. E. Lawn et al., 2009). Scaling up evidenced based solutions to reduce child mortality has become increasingly important as governments, international aid organizations, donors, and nongovernment organizations, strive towards achieving Millennium Development Goal 4 1 (MDG4), the reduction of child mortality by two-thirds by 2015 (Mangham & Hanson, 2010). In Indonesia achieving MDG 4 does not require new science and technology. Rather, it demands the expansion, and implementation of evidenced based practices throughout Indonesia to reach the large, and diverse population of 237 million persons. The retrospective case study presented here documents the piloting and scale up of community based neonatal resuscitation in West Java from 2004 to It identifies and describes factors enabling, and limiting of scale up, concluding with a proposed framework and recommendations for the scale up of evidenced based health innovations intended to significantly decrease mortality. 1 Adopted by world leaders in the year 2000 and set to be achieved by 2015, the MDGs are both global and local, tailored by each country to suit specific development needs. MDG 4 calls for the reduction of child mortality by 2/3(Basic facts about the MDGs ). 2 Community based neonatal resuscitation is defined as the package of interventions to resuscitate newborns born at home and first level facilities. It is inclusive of training and supervision of midwives, provision of basic neonatal resuscitation device, and promotion of skilled attendance at birth.

13 Section 2: Problem Statement Indonesia is considered to be on track for achieving MDG 4, the reduction of under-five mortality to 30 per 1000 live births by 2015 (Bhutta et al., 2010). However, despite the high level of political commitment, and significant declines of child mortality, there is concern within the Ministry of Health, and among Indonesian and international organizations, that Indonesia is at risk of failing to achieve MDG 4. Senior MoH leadership recognizes that to stay on track, scale up of evidenced based interventions is essential (Budihardja, 2010). The term scaling up is frequently used by senior Ministry of Health officials, and provincial and district health authorities, to connote the idea of implementing health programs and interventions across wide geographic areas (Budihardja, 2010). Yet a well defined concept of successful scale up, and the means to achieve it, has yet to be developed in the Indonesian context (personal communications with senior Child Health Directorate staff ). At the global level, although scale up is consistently scored as a top priority for program implementation and research, it remains poorly defined (Mangham & Hanson, 2010; Simmons et al., 2007). The term scale up is often applied to connote increasing coverage of a given health intervention. However, the literature includes multiple definitions, each emphasizing different aspects of the scaling up phenomenon. Some definitions focus on reaching greater numbers of people, while others address issues of policy change, equity, and sustainability (CORE Group, 2005; Hartman & Linn, 2010). In Indonesia, the Ministry of Health, international organizations and donors are faced with the challenge of how to design programs to scale up evidenced based practices in a large complex decentralized health care system. 2

14 Section 3: The Indonesian Context Indonesia s decentralized health care system, serving a population 237 million persons spread across more than 17,000 islands, is large and complex. The national government, through the Ministry of Health has authority to set guidelines, issue regulations, and make recommendations to improve public health. National funds are allocated to provincial and district level governments to implement prioritized programs as determined by the Ministry of Health. However, authority to implement recommended programs and allocate resources rests at the level of the more than 500 district governments. This offers great benefits as district authorities are able to implement programs and allocate resources to address locally identified needs. However, there are also great challenges to the decentralized system regarding scaling up health interventions throughout Indonesia (Thabrany, 2006). In a decentralized system each district can prioritize its own developmental needs. Thus, not every district prioritizes health or allocates sufficient resources. At the national level, the Government of Indonesia, including the MoH, has prioritized the achievement of the MDGs. In 2010, following the Presidential decree to prioritize achievement of MDG 4 (reduction of child mortality) and MDG 5 (reduction of maternal mortality), the MoH drafted a national strategy to achieve the MDGs (Ministry of Health, 2010). A key component of the strategy is the scale up of programs to reduce neonatal mortality as a means to significantly reduce child mortality. However, due to decentralization, not every district has to follow suit on these priorities. Trends in Child, Infant and Neonatal Mortality During the period 1991 to 2000 the Indonesian under-five mortality rate significantly decreased from 97 to 46 per As shown in figure 1.1, between 2003 and 3

15 2007 the trend slowed with a small decrease of 46 to 44 per 1000 live births. During the same time period the infant mortality rate (IMR) declined from 35 to 34 per 1,000 live births, and the neonatal mortality rate (NMR) from 20 to 19 per 1000 live births (Badan Pusat Statistic & Macro International, December 2008). Figure 1.1: Indonesia Under Five Mortality Data (DHS 2007) According to Bhutta et al. (2010), neonatal mortality now accounts for 41% of global mortality in children under five. Of the 3.8 million neonatal deaths (mortality within the first 28 days), up to half occur on the first day of life. An estimated 904,000 of the 3.8 million neonatal deaths are the result of birth asphyxia (J. E. Lawn et al., 2009). As countries make progress in reducing under-five mortality the proportion caused by neonatal mortality typically increases due to the relatively slower progress in reducing neonatal mortality (Bhutta et al., 2010). 4

16 The Indonesian trend in reducing neonatal mortality is similar to that of other countries. As shown in Figure 1.2, neonatal mortality comprises 44% of all under-five mortality. Early neonatal mortality (mortality within the first seven days of life) accounts for 35% of all under-five mortality. Birth asphyxia accounts for 37% of all neonatal mortality in Indonesia. Figure 1.2 Contribution to under five mortality (Indonesia Health Survey 2007) Section 3: Scale Up of Community Based Neonatal Resuscitation in Indonesia In 2003, birth asphyxia contributed 37% to overall Indonesian neonatal mortality (Ariawan, 2003). Through the village based midwife program, the Ministry of Health deployed midwives with the target of ensuring that every village had a village based midwife. Two large scale, United States Agency for International Development (USAID) supported maternal and newborn health programs were coming to an end. The first (Maternal and Newborn Health) focused on maternal health, and second (ASUH) on newborn health starting on day 1. The result was that care of the newborn in the first day of life, a time with the highest vulnerability and mortality, was not a focus of 5

17 interventions. In addition, Ministry of Health programs were much more focused on maternal health in comparison to newborn health (L. MacLaren in-depth interview June, 2011.) Key stakeholders within the Ministry and professional organizations began to recognize that addressing the most significant causes of neonatal mortality (birth asphyxia and low birth weight) through evidenced based approaches was essential. However, significant questions remained about how to do this in the context of a large, complex, decentralized health system in which most deliveries occur at home. In 2004, Saving Newborn Lives (SNL), led by Save the children, in partnership with PATH, the Ministry of Health, and Indonesian professional organizations, conducted a pilot study to test the feasibility and impact of training village based midwives to resuscitate newborns at home and first level facility births (PATH, 2006; Save the Children, 2004b). Inherent in the design of the operations research was the aim of generating evidence for use by key national level decision makers to influence national policy and larger scale implementation. The SNL operations research study, conducted in the district of Cirebon, West Java included: 1) testing and selection of an appropriate resuscitation device for use by village based midwives; 2) developing a midwife training curriculum for neonatal resuscitation; 3) training of midwives and midwife coordinators; 4) implementing a community based behavior change intervention to increase skilled attendance at birth; and 5) strengthening the reporting and recording system (Save the Children, 2005b). A comparison of baseline and end line results showed a 47% decrease in the crude birthasphyxia specific neonatal mortality rate from 5.1 per 1000 live births in 2004 to 2.7 per 1,000 live births in 2006 in Cirebon District (PATH, 2006; Wall et al., 2009). 6

18 According to Ministry of Health reports, community based neonatal resuscitation has now been introduced in more than 300 of the nearly 500 districts in Indonesia (Directorate of Child Health, 2010). It is now part of the standard Ministry of Health package of neonatal health services, and is included in the national in-service midwife training program, and midwife supervision (Wiknjosastro et al., 2008). Section 4: Research Study Aims The retrospective case study presented here examines how community based neonatal resuscitation was piloted, and scaled up in Indonesia from The intent is to inform the design and implementation of future government, and donor programs aimed at scaling up evidenced based health innovations in low resource settings. The case study examines the role of the Indonesian Ministry of Health, provincial and district health authorities, midwives, the Saving Newborn Lives program, donor support initiatives, and Indonesian professional organizations. The study concludes with a revised framework for planning, reviewing, and evaluating scale up of evidence based practices. Recommendations are provided to the Ministry of Health, provincial and district health authorities, and international organizations for the future design, implementation, monitoring, and evaluation of scale up programs and initiatives. Although the term scale up is frequently used in international health literature, there is not yet consensus on its precise definition. In 2007 WHO/Expandnet articulated a definition and developed a framework for scale up. For the purpose of this study, the definition developed by WHO and Expandnet will be applied. Scale up is thus defined as; the deliberate effort to increase the impact of successfully tested health innovations so as to benefit more people and to foster policy 7

19 and program development on a lasting basis (Simmons et al., 2007). This definition and the resulting framework are further discussed in detail in chapter 2 and chapter 3. Community based neonatal resuscitation is defined as the package of interventions for midwives to resuscitate newborns born at home, or primary level facilities. It includes midwife training and supervision, provision of basic resuscitation equipment, and efforts to increase demand for skilled birth attendance. Quantifying the impact of scaling up community based neonatal resuscitation on neonatal mortality is beyond the scope of this study. The focus here is on examining the process of scale up to identify enabling and limiting factors to inform future program interventions and development of a scale up framework for analysis and planning purposes. 8

20 Chapter 2: Review of the Literature Section 1: Background We have to discover how we move from our feel-good successes, how to scale up these initiatives to a depth and a breadth where we can really have an impact on poverty, where can achieve the MDGs. (Moreno-Dodson, 2005) Child mortality has significantly declined in Indonesia for decades, placing Indonesia on track to achieve the MDG 4, the reduction of child mortality by 2/3 by 2015 (Bhutta et al., 2010). This achievement required significant improvement of the health system, and the expansion of child health services targeted to reduce the most significant killers of children under five. However, as described in chapter 1, the rate of decrease in child mortality and neonatal mortality rates has slowed in recent years. To remain on track to achieving MDG 4, scale up of an integrated package of neonatal health services, targeting the most significant causes of neonatal mortality, is required. Indonesia is not alone in facing the challenge of how to scale up critical health services. The global commitment to achieving MDGs has resulted in donors, international aid organizations, UN agencies and governments to strive towards implementing large scale programs with the aim of impacting national and global trends. The idea of pilot or boutique projects is no longer considered an acceptable means of achieving impact (Hartman & Linn, 2010). The Government of Indonesia is now confronting the challenge of how to scale up evidenced based, high impact neonatal and child health interventions.

21 One such intervention is community based neonatal resuscitation as a means of decreasing neonatal mortality due to birth asphyxia, a leading cause of mortality in Indonesia. The literature review presented here describes and analyzes the existing literature on scaling up health interventions in low resource settings. The result of this review is used to frame the retrospective case study of scaling up community based neonatal resuscitation in Indonesia between 2004 and Section 2: Methodology The objective of the literature review is: 1. To define scale up in the context of global health 2. To identify existing frameworks for scale up of evidenced based neonatal or child health interventions in low resource settings 3. To identify enabling and limiting factors to scaling up evidenced based practices for neonatal or child health interventions in low resource settings. Literature/Documentation Sources The following four sources of literature were explored: Pub Med Expandnet Scaling Up Bibliography ( ExpandNet is a global network of representatives from international organizations, non-governmental organizations, academic and research institutions, ministries of health and specific projects who seek to advance the science and practice of scaling up. Evaluations and program reports, inclusive of lessons learned and recommendations, from international organizations, and global donor funded programs with a focus on newborn survival. Organizations included Save the Children, PATH, Bill and Melinda Gates Foundations, UNICEF, WHO, Mother Newborn News, and USAID Access and Basics programs, and Population 10

22 Reference Bureau. These were sourced through organization websites, as well as follow up with organization representatives to request reports not available on line. Consultations with known experts in the field for identification of other significant literature, reports or documentation. In addition, reference lists of articles and documents were scanned for materials not identified through above described literature searches. Search Terms Neonatal OR newborn OR infant OR child AND Developing country OR low income OR Indonesia OR Asia AND Intervention OR package OR services OR birth asphyxia OR intrapartum related AND Scale up OR implementation OR sustain OR sustainability Inclusion and exclusion criteria Articles in English were included that provided elements of success or failure of community based newborn, infant or child survival programs in low resource settings. This included randomized control trials, formal evaluations, and documentation of lessons learned. Articles were also included that specifically addressed elements of, or recommendations for, successful scale-up or implementation at scale. Articles and other documents were excluded if the primary focus was on secondary or tertiary care without a significant community component. Documents with specific focus on neonatal resuscitation and reduction of intrapartum-related deaths were excluded if they did not provide lessons or success factors related to scale up of 11

23 interventions, or programs. Reports or articles based on promotion of non-evidenced based interventions, as defined by 2005 Lancet Neonatal Series, were also excluded. Articles with a primary focus on evaluation, budgeting, costing or health care finance were also excluded. Finally, documentation resulting from work in resource rich contexts, or focused on high tech interventions were excluded. To ensure the scale up literature was fully explored, the search included articles and reports on neonatal health, child health, maternal health, and other community based health interventions in developing countries or low resources settings. Section 3: Results The pub med search resulted in a total of 227 articles. Following title review, 160 were eliminated based on criteria described above. A significant number of articles were eliminated as they were clinical trials without a focus on scale up or implementation beyond the study period. After abstract and full article review, 27 were included in the literature review. The Expandnet Bibliography includes a total of 131 references. Following abstract review 35 were included in the review. Review of reference list of documents identified through pub med and Expandnet documents resulted in 15 additional documents identified through title and abstract review. The literature review revealed three important categories of information: 1) definitions of scale up in the context of international health; 2) scale up frameworks; and 3) determinants of success or failure in scaling up neonatal or child health interventions. 12

24 Category 1: Defining Scale up In the field of global health, there is a growing sense of urgency as insufficient progress has been made to meet health and development needs. In this context, scaling up evidenced based solutions to reduce child mortality has become increasingly important as governments, international aid organizations, donors and national non-government organizations strive towards achieving the Millennium Development Goal 4, the reduction of child mortality by two-thirds by 2015 (Cooley & Kohl, 2006; Mangham & Hanson, 2010). The term scale up is often applied to connote an increase in coverage of a given health intervention (Mangham & Hanson, 2010). However, the literature includes multiple definitions, emphasizing different aspects of the scaling up phenomenon. Some definitions focus on reaching greater numbers of people, while others address issues of policy change, equity, and sustainability (CORE Group, 2005; Hartman & Linn, 2010). Since 2000, the term scale up has been used with increasing frequency. Mangham et al. (2010) conducted a literature search for use of the terms scale up or scaling up. Two references were identified prior to 2001 and 89 were found after However, the debate on defining scale up and how to achieve it successfully is not new in the past decade (Hartman & Linn, 2010). During the 1970s, the World Bank focused on addressing development challenges in a comprehensive and large-scale manner. In the 1980s, non-governmental organizations increasingly recognized the need to shift from small projects testing new approaches to a programs promoting sustained change. As a result, participatory and community development projects gained prominence as a means for extending reach and impact (Uvin, 1995). 13

25 Peter Uvin s 1995 scale up taxonomy is frequently cited by international aid organizations and academics (Cooley & Kohl, 2006; CORE Group, 2005; Hartman & Linn, 2010) Widely accepted taxonomy of scale up articulated by Peter Uvin, (Uvin, 1995); Quantitative scale up occurs when an organization reaches an increasing number of beneficiaries, and/or expands its geographic coverage, or its budget is significantly increased. Functional scale up occurs when organizations add new activities to their operations, thus expanding the number and types of technical intervention implemented and the number and type of beneficiaries reached. Political scale up occurs when organizations begin to actively engage in the political environment, influencing policies and decision making. Organizational scale up occurs when organizations increase their financial and management capacity through additional funding, diversification of their funding base or enhancement of internal systems, thus enabling the organization to reach a greater population. In 2000, Uvin published a follow up article entitled Think Large and Act Small: Towards a New Paradigm for NGO Scaling Up. He described two paradigms of NGO scale up. The first, scaling up through expansion, occurs when non-governmental organizations (NGOs) become larger, more professionally managed, more efficient, and reach a larger target population. The second involves a new paradigm based on multiplication and mainstreaming, spinning off organizations, letting go of innovations, creating alternative knowledge, and influencing social actors. The new paradigm recognized that scale up is not only about organizations delivering programs and services. Rather, it is about the impact of programs beyond the organization itself (Uvin, 2000). In 2000, the International Institute of Rural Reconstruction (IIRR) defined scale up as the effort to bring more quality benefits to more people over a wider geographical 14

26 area more quickly, more equitably, and more lastingly (Gonsalves, 2000). The IIRR definition recognized that scaling up goes beyond replication, and involves the dissemination and expansion of knowledge, processes and technologies. Scaling up was defined as being inclusive of expanding effects from the pilot project stage to a wider domain by communicating options to the people for decision making. It is viewed as innovation and learning that is broad-based and interactive (Gonsalves, 2000). This definition has formed the basis of work for numerous international aid organizations and donors (CORE Group, 2005; Hartman & Linn, 2010). Utilizing the taxonomy put forward by Uvin in 1995, the CORE Group 3 released a background paper entitled, Scale and Scaling Up: A Core Group Background Paper on Scaling Up Maternal, Newborn and Child Health Services. The paper adopts the definition of the USAID funded project Basics II, which defines scale up as the widespread achievement of impact at affordable cost, wherein impact is a function of coverage of a population, program effectiveness, efficiency, sustainability and equity (CORE Group, 2005). According to the Core Group Paper, non-governmental organizations define scale based on the local context and what is feasible to achieve over time. This may include working at a local district level to scale up health interventions, or at the national level for greater reach. In 2007, WHO and Expand Net articulated a definition of scale up, and a corresponding framework. Simmons et al.(2007) defined scaling up as efforts to increase the impact of innovations successfully tested in pilot or experimental projects so as to 3 The Core Group includes 50+ member organizations and networks committed to develop and diffuse innovative cross-cutting community health program strategies. CORE Group is also the implementing organization for the USAID Child Survival and Health Network Program 15

27 benefit more people and to foster policy and program development on a lasting basis. This precise definition is inclusive of quantitative and political scale up as defined by Uvin. The corresponding framework is described below in category 2, and is further elaborated in chapter 3. In a working paper for the Wolfensohn Center for Development, Hartmann et al. (2008) explained that scaling up is about political and organizational leadership, about vision, values and mindset, and about incentives and accountability all oriented to make scaling up a central element of individual, institutional, national and international development efforts. The authors adapted the 2005 World Bank definition, defining scale up as a means to expand, adapt and sustain successful policies, programs or projects in different places, and over time to reach a greater number of people (Hartman & Linn, 2010). This definition is in contrast to that of the IIR and Core Group in that it does not directly address equity and speed; both of which are of particular interest to international non-government organizations. However, the authors also refer back to the taxonomy put forward by Peter Uvin including; quantitative, functional, political and organizational scale up, explaining that each are interconnected. In their 2010 review article on key issues related to scale up, Mangham et al. (2010) explain that although frequently used, the term scaling up lacks a formal definition. As such, research to document or explain scale up is difficult because there is no consensus on terminology or frameworks to study scaling up in the context of international health. The authors acknowledge the precise nature of the 1995 taxonomy described by Uvin, and the WHO/Expandnet definition articulated by Simmons et al. (2007). 16

28 According to Mangham et al., (2010) scale up is used to describe both the objective and the process. The term refers to the process of reaching an increasing number of persons. Alternatively, it is used to describe an expansion of specific projects, programs or interventions resulting in achieving universal or large scale coverage of a specific health intervention or package of services. Following the Mangham and Hanson et al. (2010) review article, Gilson and Schneider (2010) highlighted the importance of considering both political commitment and strategic management of scaling up. The authors explain that scaling up is not just about the transfer of knowledge or information dissemination, but is essentially a learning process in which the adaptation of the innovation to local realities is vital. Category 2: Frameworks for Scale Up Relevant to the field of global health, the literature has revealed two subcategories of frameworks, a) general frameworks for scale up of a specific health intervention or package of services, and b) frameworks specific to scale up of neonatal health interventions. Subcategory 2a: General Scale Up Frameworks The literature revealed a number of frameworks put forward by international organizations to conceptualize and plan for scale up. Although not specific to scale up of neonatal health interventions, they remain relevant. In 2005, Management Systems International developed a field tested framework and guidelines for improved management of the scaling up process. The framework is described by the authors as a practical approach for use by those intending to take pilot projects to scale (Cooley & Kohl, 2006). 17

29 Effective scale up according to MSI: Step one, development of a scaling up plan includes the tasks of; creating a vision, assessing scalability, filling information gaps and preparing the scale up plan. Step two, establishment of the preconditions for scaling up includes the tasks of; legitimizing change, building a constituency and realigning and mobilizing resources. Step three, implementation of the scaling up process includes; modifying organizational structures, coordinating actions, tracking performance and maintaining momentum. In 2007, Simons et al (2007) developed a comprehensive conceptual framework for thinking about the process of scaling up experimental innovations. The authors define scale up as efforts to increase the impact of innovations successfully tested in pilot or experimental projects so as to benefit more people, and to foster policy and program development on a lasting basis. According to the authors,, scale up occurs within a multi dimensional system in which an innovation is introduced. Scale up of the innovation is then influenced by the following: The research team or organization involved in the development and testing of the innovation The user organization that is expected to adopt and implement the innovation The scaling up strategy that determines the means by which the innovation is communicated, transferred or promoted. The environment in which scale up occurs, including the policy setting, the political system, bureaucratic culture, the health sector, socioeconomic and cultural contexts and the influence of global trends. See Chapter 3 for an in depth description of the WHO / Expandnet framework, and its applicability to scaling up neonatal resuscitation in Indonesia. Multiplicative strategies defined as the deliberate use of a learning strategy to influence organizations to replicate programs is being utilized by an increasing number of 18

30 NGOs. The Seed Scale model developed by Carl Taylor is designed to enable community leaders and stakeholders to systematically learn from successful projects and apply learning to new areas (CORE Group, 2005). The framework is guided by the following steps: SEED One: NGO establishes and learns from a model project or community SEED Squared: The model project is transformed from a demonstration project to a learning center for others. SEED Cubed: The government creates an enabling environment for rapid up-take, with the NGO continuing to promote systematic extension to increase geographic coverage. In How to Mobilize Communities for Health and Social Change Howard-Graburn and Snetro (2007) emphasized the need for systematically planning for scale up during the project design and early implementation stages. The authors describe the following steps: Before Scale Up Have a vision to scale up from the beginning Determine the effectiveness of the approach Assess the potential to scale up Consolidate, define, and refine the approach Build a consensus for scale-up Advocate for supportive policies As you scale-up Define roles, relationships and responsibilities of implementing partners Secure funding and other resources Develop partner capacity to implement Establish and maintain and monitoring and evaluation system Support institutional development for scale 19

31 Sub-category 2: Frameworks for the scale up of neonatal health interventions. Low tech, low cost solutions exist to save newborn lives. What is lacking is implementation science on how to scale up these interventions in low resource settings The 2005 Lancet Neonatal Survival series identified 16 high impact low tech evidenced based interventions to save newborn lives in low resource settings (Darmstadt et al., 2005). Since then, numerous authors have elaborated on what interventions should be scaled up. A review by Wall et al (2009) confirmed the effectiveness of neonatal resuscitation by community based health providers. They also noted that evidence is lacking on how to effectively scale up such interventions in low resource settings. This was echoed by Lawn et al. noting the need to prioritize research on implementation science (J. E. Lawn, Kerber, Enweronu-Laryea, & Massee Bateman, 2009). Also in the 2005 Lancet Neonatal Survival series, Knippenberg et al.(2005) presented a model for scaling-up of neonatal care in countries based on a systematic datadriven decision making process, and a participatory rights-based policy process. They began with the statement that interventions with the greatest effect on neonatal deaths are less dependent on technology and commodities than on people with skills. Utilizing a review of the evidence, the authors present a framework for systematic scale up of neonatal health that incorporates two parallel processes: a systematic prioritization and management process, and human rights based political process (Knippenberg et al., 2005). The authors propose a phased approach to scale-up dependent on magnitude of NMR, and other contextual factors regarding the health system and existing coverage rates of health services. The authors recommended that nations with high NMR (defined as greater than 45/1,000 live births) prioritize family behaviors and begin with district level health system strengthening. In countries with an NMR of 30-45/1,000 outreach 20

32 services and family community care, increasing coverage of skilled care, and improving district and sub-district level facilities are recommended (Knippenberg et al., 2005). Albeit a systematic approach questions remain unanswered regarding what delivery strategies and resources are required to make scale-up feasible for neonatal resuscitation and other evidenced based interventions. Darmstadt et al. (2005) reviewed 16 evidenced based neonatal survival intervention packages to determine the potential effect and estimated costs in 75 countries, using national data on neonatal mortality, causes of mortality and coverage rates. The proposed framework provides a practical approach for policy makers and programmers. However, as identified by the authors, the underlying assumptions regarding efficacy and effectiveness assume that interventions are implemented under ideal conditions within a health system with the capacity to scale up interventions. Thus, it does not take into account barriers and challenges that must be addressed in implementing programs to achieve scale up of neonatal interventions. In 2008, Darmstadt et al. (2008) published a further analysis of the cost and impact of scale-up of integrated packages of neonatal interventions. The phased approach to scale up was guided by the principles of: Initial emphasis on expanding outreach coverage, especially for tetanus toxoid coverage and family community care Strengthening of clinical care standards Integrating programs for mothers and newborns across service delivery modes Phased introduction of additional interventions as health system capacity increases. 21

33 Darmstadt et al. (2008) Key Messages Effective interventions are available to save lives of newborns Interventions can be bundled in cost effective packages for delivery in existing health systems Universal implementation could avert up to 72% of neonatal death in 75 countries Outreach and health education creates demand for skilled care, and improve care seeking can bring early success Simultaneous expansion of clinical care for newborns and their mothers is essential to achieve MDG4 As in their earlier article, and in the scale up framework by Knippenberg et al. (2005), the analysis did not take into account barriers present in existing health systems. Thus, the authors are not able to address the question of how to deliver proposed interventions within the constraints of existing health care systems. They can only estimate cost and impact if scale is achieved. Within the context of program implementation, others have discussed elements of a framework for scale up. The global USAID Access program, operational in over 30 countries, resulted in recommendations for an integrated approach to community and facility based maternal and newborn programming and implementation (Access/USAID, 2006). Described as the Home to Hospital Continuum of Care (HHCC), the framework brings together evidence based practices for prevention of both maternal and newborn mortality. The elements highlighted by the Access program are based on extensive programmatic experience in over 30 countries, and take into account barriers to implementation. The report Opportunities for Africa s Newborns also presents a framework for scale up based on programmatic evidence (J. Lawn & Kerber, 2006). The report resulted from the collaboration of over 60 authors and numerous programs and research studies. It framed recommendations for program managers and health professionals working towards scaling up neonatal health interventions in Africa. The authors stated that a 22

34 participatory political process and a systematic management and prioritization process are required for success at scale. This is reminiscent of the framework presented by Knippenberg et al. (2005). The global Saving Newborn Lives, funded by the Bill and Melinda Gates Foundation and implemented by Save the Children has been actively addressing the challenges of scale up with its 19 country programs. In over 10 years of implementation SNL has found that defining, measuring, and documenting progress towards and success of scale up of neonatal health interventions has been a challenge for governments and the Saving Newborn Lives program itself. As such SNL has a developed a scale up bench mark tool to assist individual country programs to track progress towards scale up. The benchmark tool includes recognizes that scale up occurs over a continuum beginning with preparatory phases and mobilization of resources (Save the Children, 2011). This process is important to measure and document. Recommendations resulting from consultation with the SNL technical steering committee in May 2011 included the need to better the pathway to scale up, development of tools to capture and document the complexities of the process, and the importance of measuring impact at scale (Saving Newborn Lives, 2011). The global Maternal Child Health Integrated Program (MCHIP), funded by USAID and operational in over 30 countries is also committed to scaling up health innovations in low resource settings. Combining program experience from multiple countries MCHIP has developed a scale work framework, that like SNL s benchmarks recognizes the importance of working across a continuum beginning with a preparatory phase. The framework is includes the following phases (Hodgins, 2011): 23

35 Phase 1, Pre-introduction to move from a state of being unaware or uninterested to consensus building Phase 2, Definitive decision to move from consensus building to motivation Phase 3, Introduction to move towards actions Phase 4, Early implementation to continue with necessary actions Phase 5, Mature implementation to sustain change Category 3: Factors of success and constraints for scale up Although identified as a research priority, there is little rigorous research specific to scaling up (Hartman & Linn, 2010; Peterson, 2010). However, the literature reveals a number of limiting and enabling factors based on programmatic documentation and case studies. Factors described below are not specific to scale up of neonatal health interventions. Rather they based on efforts to scale up a broad range of health interventions in low resource settings, and are seen as generalizable to the scale up of neonatal health interventions. Enabling Factors for Scale up Ensure a well articulated vision for scale up is part of program design: Successful scale up requires a vision for moving from small scale pilot, or research to large scale sustained implementation (Cooley & Kohl, 2006; Hartman & Linn, 2010; Simmons et al., 2007). In a case study of scaling up family planning service innovations in Brazil, Diaz et al. (2007) documented the importance of integrating a vision of scale up from the early stages of project design and implementation.. Well defined plans and clear strategy for scale up: Sound planning and management are cited throughout the literature as critical factors for successful scale 24

36 up. The first step in many scale up frameworks is often development of a sound plan (Biswanger & Aiyar, 2003; Cooley & Kohl, 2006; Darmstadt et al., 2008; Hartman & Linn, 2010; Knippenberg et al., 2005). Adaptation of pilot design and scale up strategy to reflect the local context: The importance of in-depth analysis and developing an understanding of the local context cannot be underestimated. Numerous case studies emphasize the importance of ensuring that pilot designs, and scale up strategy are adapted to reflect local needs, opportunities, and national realities (Diaz, Simmons, Diaz, Cabral, & Chinaglia, 2007; Hartman & Linn, 2010; Kaufman, Erli, & Zhenming, 2007; Phillips, Nyonator, Jones, & Ravikumar, 2007; Simmons et al., 2007; Skibiak, Mijere, & Zama, 2007). A comparative analysis of scaling up reproductive health services in Ghana and Bangladesh found that scale up of similar innovations requires significantly different strategies based on cultural context and government systems (Phillips et al., 2007). In the case study of scaling up family planning in Brazil, Diaz et al. (2007) emphasized the importance of examining the environmental context in order to set realistic goals and to maximize existing opportunities. In contrast to adapting to the local context, scale up often results in a perceived need to standardize approaches across diverse geographic areas. As demonstrated in the case of expanding contraceptive choice in Zambia, a major challenge was ensuring that scaling up did not occur at the expense of local ownership (Skibiak et al., 2007). Participatory planning to ensure demand for, and local ownership of pilot innovations and scale up strategies: Ensuring there is demand for pilot intervention and its design is an important means of engaging stakeholders (Kaufman et al., 2007). 25

37 This is evidenced by experience from Indonesia (Save the Children, 2005b) and China (Kaufman et al., 2007). Phillips et al. (2007) also describes how participatory planning was a key element of success in the scale up of reproductive health initiatives in Bangladesh and Ghana. Utilization of a phased approach that prioritizes packages of neonatal or health interventions: As per the scale up frameworks put forward by Darmstadt et al.(2005) and Knippenberg et al. (2005), phased introduction of packages of interventions is recommended. The timing of introduction needs to take into account the local context and epidemiology. This assumes that the health system can only absorb a finite number of new inputs. In addition, the global SNL and MCHIP programs have begun to develop scale up benchmarks and frameworks that is built on the assumption that scale up occurs over a continuum, with each phase an important part of the process (Hodgins, 2011; Save the Children, 2011). Strengthening of health systems: The work of UNICEF, WHO, and the global Access Program funded by USAID all emphasize the importance of improving health systems as an essential component of successful scale up. The Access program specifically states that strengthening essential elements of health systems, including human resources, pharmaceutical management and logistics, financing, quality assurance, governance, and information systems is key to achieving success at scale (Access/USAID, 2008). Weak health systems are often cited as a significant constraint to scale up (Access/USAID, 2008; Darmstadt et al., 2005; Darmstadt et al., 2008; Knippenberg et al., 2005; UNICEF, 2009; WHO, 2003). In a case study of scaling up health interventions in Chad, Wyss et al. (2003) specifically noted that emphasis on the absorptive capacity of the health system is essential. 26