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Application summary Application title This should be the title of your proposed project. Proposed duration of funding (months) Proposed start date Name of administering organisation Please enter the name of the organisation where you intend to hold the award. If your application is successful, this is the organisation that will be responsible for administering the award. Lead applicant's address at administering organisation Department/Division Organisation Street City/Town Postcode/Zipcode Country Please enter the address where you will be working at the administering organisation. If your application is successful, this is the address that will be used in the award letter. Research funding area Indicate the relevant research funding area for the proposed project. There will be some proposals that do not fall naturally into a research area, or cross a number of them (e.g. multidisciplinary research). In these circumstances the research area that seems most appropriate, based on the fundamental purpose of the proposed research, should be selected. Lead applicant Lead applicant details Full Name Page 1 of 7

Department Division Organisation Address Line 1 City/Town Postcode Country Telephone No. Email Address Career history (current/most recent first) From To Position Organisation Please provide details of your current position (if applicable) and all previous posts held, listing most recent first. Education/training From To Qualification Subject Organisation Please provide details of relevant education/training, listing the most recent first. Source(s) of personal salary support Your source of salary may have an impact on your eligibility to apply for Wellcome Trust funding. Please, therefore, state the source of funding of the salary of your post (for example, if it is funded through your organisation s block grant from a Higher Education Funding Council). If your salary is being funded from more than one source, please provide details of all funding sources, including their relative contributions. If there are any ties on intellectual property rights or publications arising from the research you undertake, please contact the Wellcome Trust for advice. Restrictions on intellectual property may affect your ability to apply to the Wellcome Trust. If you are not currently in employment, this question should be answered not applicable. Experience relevant to this proposal Please summarise your key achievements and experience which are relevant to this proposal. Please summarise what you consider to be your key achievements and experience and their relevance to this proposal; state which period of your career they relate to. You do not need to list all of your positions. Career breaks Have you had any career breaks or periods of part-time work, for example parental or long-term sick leave? We encourage applications from researchers who have taken career breaks, and wish to ensure that any such breaks are duly taken into account when considering your track record. Please state when and for what period of time you took a break, or were working on a part-time basis. We are not seeking any information on the reasons for this break so please do not provide this here, including sharing any sensitive personal health information. Page 2 of 7

Please provide details Do you wish to undertake this award part time? If you wish to undertake this award part time, you must be employed on a part-time basis. Please contact the Trust to discuss your requirements. Career contributions What are your most important research-related contributions to your field to date? These may include contributions to health policy or practice, or to technology or product discovery and development. The examples you choose can be taken from any stage of your career. In each case, please state what the achievement was, when it came about, why you think it is important and what impact it has had. Research outputs List up to 20 of your most significant research outputs, ensuring that at least five of these are from the last five years. For 10 of these outputs, provide a statement describing their significance and your contribution (up to 50 words per output). Research outputs may include (but are not limited to): Peer-reviewed publications and preprints Datasets, software and research materials Inventions, patents and commercial activity For original research publications indicate those arising from Wellcome-funded grants in bold, and provide the PubMed Central ID (PMCID) reference for each of these. Please refer to guidance notes. Please give citation in full, including title of paper and all authors*. Citations to preprints should state Preprint, the repository name and the articles persistent identifier (e.g DOI). (*All authors, unless more than 10, in which case please use et al, ensuring that your position as author remains clear.) You should include here systematic reviews (e.g. Cochrane Reviews) and meta analyses, but exclude abstracts and literature reviews. We encourage the inclusion of articles published via open research publishing platforms, such as Wellcome Open Research, providing they have passed peer review. Preprints, i.e. complete manuscripts that have been submitted to a preprint repository or service (e.g. biorxiv, PeerJ Preprints, arxiv, SocArXiv or PsyArXiv), can be included only if they have a permanent identifier such as a DOI or arxiv identifier. Total number of peer-reviewed publications which you have authored/coauthored. Please exclude abstracts and literature reviews. You should include here systematic reviews and meta analyses. We encourage the inclusion of articles published via open research publishing platforms, such as Wellcome Open Research, providing they have passed peer review. Page 3 of 7

Current and recent research funding (including Wellcome Trust grants) Please list all held in the last five years and any key prior grants (list the most recent first). State the name of the awarding body, name(s) of grantholder(s), title of project, amounts awarded, your role in the project, and start and end dates of support. For all active grants, indicate the number of hours per week that are spent on each project. Success in obtaining funding for your research forms part of the assessment of your track record. In addition to research grants, please include details of any recurrent or core funding support that you have held in the last five years, including any Wellcome Trust awards. Please state clearly your role in obtaining the awards, for example, whether you held them in your own right as lead applicant, co-applicant, or as part of a consortium. Please state the value of your own component of the award and the percentage of your time spent on the research. Applicants Applicants are expected to be actively involved in the project. 1 Applicant Full Name Department Division Organisation Address Line 1 City/Town Postcode Country Telephone No. Email Address Career history (current/most recent first) From To Position Organisation Education/training From To Qualification Subject Organisation Applicants are expected to be actively involved in the project. Source(s) of personal salary support Your source of salary may have an impact on your eligibility to apply for Wellcome Trust funding. Please, therefore, state the source of funding of the salary of your post (for example, if it is funded through your organisation s block grant from a Higher Education Funding Council). If your salary is being funded from more than one source, please provide details of all funding sources, including their relative contributions. If there are any ties on intellectual property rights or publications arising from the research you undertake, please contact the Wellcome Trust for advice. Restrictions on intellectual property may affect your ability to apply to the Wellcome Trust. Page 4 of 7

If you are not currently in employment, this question should be answered not applicable. Experience relevant to this proposal Please summarise your key achievements and experience which are relevant to this proposal. Please summarise what you consider to be your key achievements and experience and their relevance to this proposal; state which period of your career they relate to. You do not need to list all of your positions. Career breaks Have you had any career breaks or periods of part-time work, for example parental or long-term sick leave? We encourage applications from researchers who have taken career breaks, and wish to ensure that any such breaks are duly taken into account when considering your track record. Please state when and for what period of time you took a break, or were working on a part-time basis. We are not seeking any information on the reasons for this break so please do not provide this here, including sharing any sensitive personal health information. Please provide details Do you wish to undertake this award part time? If you wish to undertake this award part time, you must be employed on a part-time basis. Please contact the Trust to discuss your requirements. Career contributions What are your most important research-related contributions to your field to date? These may include contributions to health policy or practice, or to technology or product discovery and development. The examples you choose can be taken from any stage of your career. In each case, please state what the achievement was, when it came about, why you think it is important and what impact it has had. Research outputs List up to 20 of your most significant research outputs, ensuring that at least five of these are from the last five years. For 10 of these outputs, provide a statement describing their significance and your contribution (up to 50 words per output). Research outputs may include (but are not limited to): Peer-reviewed publications and preprints Datasets, software and research materials Inventions, patents and commercial activity For original research publications indicate those arising from Wellcome-funded grants in bold, and provide the PubMed Central ID (PMCID) reference for each of these. Please refer to guidance notes. Page 5 of 7

Please give citation in full, including title of paper and all authors*. Citations to preprints should state Preprint, the repository name and the articles persistent identifier (e.g DOI). (*All authors, unless more than 10, in which case please use et al, ensuring that your position as author remains clear.) You should include here systematic reviews (e.g. Cochrane Reviews) and meta analyses, but exclude abstracts and literature reviews. We encourage the inclusion of articles published via open research publishing platforms, such as Wellcome Open Research, providing they have passed peer review. Preprints, i.e. complete manuscripts that have been submitted to a preprint repository or service (e.g. biorxiv, PeerJ Preprints, arxiv, SocArXiv or PsyArXiv), can be included only if they have a permanent identifier such as a DOI or arxiv identifier. Total number of peer-reviewed publications which you have authored/coauthored. Please exclude abstracts and literature reviews. You should include here systematic reviews and meta analyses. We encourage the inclusion of articles published via open research publishing platforms, such as Wellcome Open Research, providing they have passed peer review. Current and recent research funding (including Wellcome Trust grants) Please list all held in the last five years and any key prior grants (list the most recent first). State the name of the awarding body, name(s) of grantholder(s), title of project, amounts awarded, your role in the project, and start and end dates of support. For all active grants, indicate the number of hours per week that are spent on each project. Success in obtaining funding for your research forms part of the assessment of your track record. In addition to research grants, please include details of any recurrent or core funding support that you have held in the last five years, including any Wellcome Trust awards. Please state clearly your role in obtaining the awards, for example, whether you held them in your own right as lead applicant, co-applicant, or as part of a consortium. Please state the value of your own component of the award and the percentage of your time spent on the research. Details of proposal Project summary Please provide a summary of your proposed project. (200 words max.) Aims and objectives Please describe the aims and objectives of your proposal and the approaches you will take to achieve these. Include milestones, if appropriate. (1,000 words maximum) You may provide your answer in text entry format or as a PDF attachment. If you are uploading this information, the uploaded document must be in 11 point Arial font and portrait format. Page 6 of 7

(1000 words max.) Collaborative approach Briefly outline why a collaborative approach is required to deliver the project, and describe the roles of all applicants. Additional information Please provide any other relevant information in support of your application. Approximate costs Currency requested Please select the currency requested for award Salaries Materials and consumables Equipment Other significant costs Total () Page 7 of 7