ielab and Wyss Zurich - Key building blocks of entrepreneurship support at ETH

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ielab and Wyss Zurich - Key building blocks of entrepreneurship support at ETH grow-apéro, June 7, 2017

ETH Zurich at a glance Founded in 1855 Driving force of industrialisation in Switzerland ETH Zurich today ~ 19,800 students ~ 500 professors ~ 10,000 employees (incl. Ph.D. students) ~ 25,000 people from 100 different countries CHF 1.8b annual budget Global University Ranking: Times Higher Education No. 1 in continental Europe, and No. 9 in the world (2016) 12.06.2017 2

Mission of ETH One of the key tasks of ETH: technology transfer: to exploit research findings 12.06.2017 3

More innovation and entrepreneurship at ETH! 12.06.2017 4

The importance of startups for job creation (USA) 12.06.2017 5

Entrepreneurship: Integral part of ETH culture! Focus Projects, TLabs, SPH, Pioneer Fellowships Budding Entrepreneurs Company Builders Institutes/SPH/ Departments ielab Wyss/Technopark/ Innovation Park The World ETH Entrepreneur Club (3000) ETH Juniors (8000) 12.06.2017 6

What ETH entrepreneurs would have wanted Peer home Coaching Networking A second home ( a biotope ) for like-minded young ETH scientists with entrepreneurial aspirations: Peer support and peer pressure! Supervision and support by experienced, successful entrepreneurs with a similar background: Compelling role models Low-threshold access to all ETH resources, in particular ETH transfer, and to the complete network of the entire ETH ETH s answer: The innovation & entrepreneurship Lab 12.06.2017 7

ielab in a nutshell Collaborative open spaces ( biotopes ) for close interactions between young entrepreneurs: Peer support and peer pressure! Individual counseling by highly experienced coaches, who are all successful serial entrepreneurs themselves Effective access to the enormous network of ETH and the various ETH services through the embedded ielab team: Innovation Sherpas Complementary training, individual support (Pioneer Fellowships) and events (ielab weekly lunch seminar, Entrepreneur Club ) 12.06.2017 8

ielab: Engineering/ICT and Life Sciences 12.06.2017 9

Integral opportunity: ETH Pioneer Fellowship Seed money: CHF 150 000 over 18 months Workplace in one of the ielabs (offices, labs, workshop, ) ICT infrastructure and communication tools Coffee corner (that s where it happens!) Coaching by successful serial entrepreneurs Access to all services of ETH transfer Use of the ETH network for finding alliance partners Use of the ETH Foundation network for finding investors Support by the host professor Networking events (meet the pioneers, startup-dinner, ) 12.06.2017 10

The ielab Entrepreneurship training program ielab Seminars Round Tables Canvas Trainings Immersion Experience 12.06.2017 11

Wyss Zurich Bridging the valley of death ielab / Pioneer Fellows = Projects / Studies Infrastructure (GLP&GMP) First-in-Man Trials Therapy Bench / Invention Bedside / Product Product Des. & Dev. Prototype Testing Products Basic Research Pre-Clinical Res. / PoC Clinical Translation Tech. Transfer Clinic / Market June 12, 2017 Institutions, research grants, etc. Venture capital, industry partnerships 12.06.2017 12

Focus Accelerating translational research Fields of focus Regenerative Medicine Robotic Technologies Method Combining expertise of ETH Zurich / UZH talent pool Multidisciplinary teams Impact Clinical therapies for patients Breakthrough innovations for society Outputs Commercialization Clinical application through spinoffs, outlicensing deals and trade sales June 12, 2017 12.06.2017 13

Organization Combining the best of both worlds ETH Zurich & UZH Wyss Zurich Board (ETH Zurich, UZH, Wyss Foundation) Input Basic Research ETH Zurich / UZH Wyss Zurich Proposals Evaluation Board Core Faculty Wyss Zurich Evaluation Process Co-Directors: S. Hoerstrup R. Siegwart Operations Office Wyss Zurich Translational Technology Regenerative Platforms Medicine Platform Robotics Platform Hybrid Technologies Associate Faculty Platform Leaders Technology Platforms Projects Projects Projects Output Solutions Spin-off Trade sale License 12.06.2017 14

A unique model Building blocks of Wyss Zurich Funding for personnel expenses & translational R&D Access to technology platforms & infrastructure Funding for early-phase clinical trials Coaching & mentoring by subject-matter experts 12.06.2017 15

Technology Platforms Scope of activities Regenerative Medicine Platform from bench to bedside Translation of medical innovations in first-in-man studies. Manufacturing clinical grade products (GMP). Enrolment of clinical studies and technologies according to GCP in collaboration with Swissmedic and the related international authorities (e.g. EMA, FDA). Fully certified, state-of-the-art technical and scientific platform with ISO 13485 Quality Management System in place for Medical Devices. Covers expertise in cellbased therapies, tissue engineering, organoid technologies. Robotics Platform from invention to commercial product Successful conversion of promising scientific results into products. Technology and engineering team, who supports the Wyss Zurich Projects in their transfer to the market. Specialists covering core competences: - Systems and industrial design, - Mechatronic and software development, - Product and business development. Will comprise an advanced prototyping facility for mechatronic systems. 12.06.2017 16

Wyss Zurich Projects A good balance ETIMSred UZH Establishing immune tolerance in Multiple Sclerosis LifeMatrix UZH / ETH Zurich Tissue-engineered human matrices to repair and regenerate the heart Regenerative Medicine & Robotics Liver4Life UZH / ETH Zurich Regeneration of the human liver outside of the body HYLOMORPH UZH / ETH Zurich Improving the biocompatibility of implantable medical devices denovoskin UZH Novel bio-engineered skin grafts for clinical application CeNeReg UZH / ETH Zurich Enhancing regeneration of the injured central nervous system Regenerative Medicine Robotics ANYmotion ETH Zurich Electrical legged robots with algorithms for advanced mobility Wingtra ETH Zurich Flying robots that take-off and land like helicopters, but fly like planes Zurich Eye (successfully completed) UZH / ETH Zurich Replicating the human visual perception for robots 12.06.2017 17

ETH Living a Culture of Innovation and Entrepreneurship Thank you! ielab: ielab Video: Wyss Zurich: www.ethz.ch/ielab www.youtube.com/user/ethzurich www.wysszurich.uzh.ch ETH transfer: ETH Pioneer Fellowships: www.transfer.ethz.ch www.vpf.ethz.ch/services/pioneergrants