CURRENT ADVANCES IN CARDIOVASCULAR CARE 2016

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CURRENT ADVANCES IN CARDIOVASCULAR CARE 2016 A C M E / C N E - C E R T I F I E D C O U R S E REGISTRATION 7:00 7:45 am SCIENTIFIC PROGRAM 7:45 am 4:45 pm The Wyndham Garden Exton Valley Forge 815 North Pottstown Pike Exton, PA 19341 I N C O N J U N C T I O N W I T H A N D C O U R S E D I R E C T O R Nicholas Vaganos, MD C O U R S E C O - D I R E C T O R S Timothy Boyek, MD Mian A. Jan, MD Steven Weiss, MD, MBA www.penncmeonline.com

Program Overview & Target Audience The purpose of this educational activity is to provide information on recent advances in the field of cardiovascular medicine and how they impact the management of patients. The emphasis will be on evidence-based, best practice standards of care and on practical and clinical issues faced on a daily basis by the health care team. This activity has been designed for primary care physicians, interventional cardiologists, clinical cardiologists, cardiac surgeons, vascular surgeons, hospitalists, emergency medicine specialists, interventional radiologists, nurses, technologists and other members of the health care team who want to enhance their knowledge of current advances in the management of patients with heart and vascular disease. Course Objectives: Upon completion of this activity, participants should be able to: Describe new diagnostic techniques, pharmacotherapy and procedures utilized in the care of the patient with cardiovascular disease List two or more strategies used by the health care team to manage the patient with diabetes and heart disease Indicate when a pharmacologic stress test should be considered in the patient with suspected coronary heart disease Apply evidence-based strategies in the management of patients with asymptomatic valvular disease Describe two new therapies in the treatment of congestive heart failure List two or more classes of medications that can cause QT prolongation Describe the most current eligibility criteria used in identifying patients eligible for TAVR Apply knowledge of genetic testing in the management of patients with cardiovascular disease Identify the role of PCSK9 inhibitors in the treatment of patients with elevated cholesterol Hosting Department and Organization Current Advances in Cardiovascular Care 2016 is hosted by the Department of Cardiovascular Services at Penn Medicine Chester County Hospital. Accreditation Physicians: The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Nurses: The Hospital of the University of Pennsylvania, Department of Nursing Education, Innovation and Professional Development is an approved provider of continuing nursing education by the PA State Nurses Association, an accredited approver by the American Nurses Credentialing Center s Commission on Accreditation. Designation of Credit Physicians: The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 7.5 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nurses: The program will award 7.25 contact hours. Certificates and Transcripts: After the symposium has concluded, all participants will receive a follow-up email with instructions and a link. Once participants submit the request for credit, the earned credits will be available for viewing on a transcript and certificates will be available for printing at www.penncmeonline.com. Please note that the individual certificate will not be mailed. Disclosures The Perelman School of Medicine at the University of Pennsylvania, Office of Continuing Medical Education, adheres to the ACCME Standards for Commercial Support. Faculty disclosure information will be made available in the conference materials and syllabi. Faculty members are also expected to disclose to participants any discussions of off-label and/or investigational uses of pharmaceutical products within their presentations. Services for the Disabled If special arrangements are required for an individual with a disability to attend this meeting, please contact the Office of Continuing Medical Education no later than February 19, 2016 at 215-898-8005. Nondiscrimination Statement The University of Pennsylvania values diversity and seeks talented students, faculty, and staff from diverse backgrounds. The University of Pennsylvania does not discriminate on the basis of race, sex, sexual orientation, gender identity, religion, color, national or ethnic origin, age, disability, or status as a Vietnam Era Veteran or disabled veteran in the administration of educational policies, programs or activities; admissions policies; scholarship and loan awards; athletic, or other University administered programs or employment. Questions or complaints regarding this policy should be directed to Executive Director, Office of Affirmative Action and Equal Opportunity Programs, 3600 Chestnut Street, Sansom Place East Suite 228, 19104-6106 or 215-898-6993 (Voice) or 215-898-7803 (TDD). www.upenn.edu/affirm-action.

Registration Fees The registration fees for the Current Advances in Cardiovascular Care 2016 are the following: $99 for Physicians, $79 for Physician Assistants, Nurse Practitioners and Certified Registered Nurse Anesthetists. $59 for Nurses and Healthcare Professionals. The registration fee is $49 for Chester County Hospital and Penn Medicine employees, faculty and staff with a valid Chester County Hospital or Penn Medicine ID. The registration fee includes attendance to the symposium, a course booklet, a link to view the presentations online, continental breakfast, mid-morning and afternoon breaks as well as lunch. If you are registering with a credit card, please register online at www.penncmeonline.com, then clicking on CME Activities/Live Events. To pay by check, complete the registration form and mail it in with your check. We cannot accept faxed or mailed registration forms with credit card information. Please see the top of the registration form for mailing information. All registrations will be confirmed in writing if your registration form and fee are received by February 19, 2016. Cancellation and Refund Policy In order to process refunds for course withdrawals, cancellations must be received in writing by February 19, 2016 and are subject to a $15.00 service charge. No refunds will be issued thereafter. The University reserves the right to cancel or postpone this course due to unforeseen circumstances. In the event of a cancellation or postponement, the University will refund registration fees but is not responsible for related costs or expenses to participants, including cancellation fees assessed by hotels, airlines, and travel agencies. Meeting Location Current Advances in Cardiovascular Care 2016 will be held at The Wyndham Garden Exton Valley Forge, 815 North Pottstown Pike, Exton, PA 19341 484-879-2511

COURSE DIRECTORS Nicholas Vaganos, MD Course Director, Penn Medicine Chester County CME Timothy Boyek, MD Chief of Cardiology Section Medical Director of Invasive Cardiology Mian A. Jan, MD Chairman, Department of Medicine Steven J. Weiss, MD, MBA Chief of Cardiac Surgery COURSE FACULTY Hanna Ahmed, MD Cardiologist Christopher Bruno, DO Endocrinologist Fermin C. Garcia, MD Assistant Professor of Clinical Medicine Director, Electrophysiology Laboratory Pennsylvania Hospital Perelman School of Medicine at the University of Pennsylvania Mariell Jessup, MD Professor of Medicine Perelman School of Medicine at the University of Pennsylvania Dean G. Karalis, MD Clinical Professor of Medicine Cardiology Director of Preventive Cardiology Pennsylvania Hospital Anjali Owens, MD Assistant Professor of Medicine Perelman School of Medicine at the University of Pennsylvania Umer Saleem, MD Cardiologist Kurt Schillinger, MD, PhD Medical Director, Afib Ablation Program Prashanth Vallabhajosyula, MD, MS Assistant Professor of Surgery Division of Cardiovascular Surgery Perelman School of Medicine at the University of Pennsylvania W. Clay Warnick, MD Director, Cardiovascular Program Co-Director, Heart Failure Ambereen M. Jan, MD Chief of Nephrology Paoli Hospital Paoli, PA

CURRENT ADVANCES IN CARDIOVASCULAR CARE 2016 A G E N D A The Wyndham Garden Exton Valley Forge 815 North Pottstown Pike Exton, PA 19341 A CME/CNE-CERTIFIED COURSE 7:00 7:45 AM Registration and Continental Breakfast 7:45 8:00 AM Welcome Nicholas Vaganos, MD 8:00 8:45 AM Key Note: Is It Possible to Reduce the Incidence of Cardiovascular Disease Still Further? Prevention and Treatment Care Models Epidemiology: What do we Need to Measure? Mariell Jessup, MD 8:45 9:15 AM Stress Testing, Choosing the Right Test Appropriate Use Criteria, What do They Tell Us? Matching the Patient to the Test Umer Saleem, MD 9:15 9:45 AM PCSK9 Inhibitors Review Outcomes From Recent Trials The Role of LDL Lowering Medications in Overall Plan of Care in Patients at Risk for CVD Dean Karalis, MD 9:45 10:00 AM Q & A 10:00 10:15 AM Break VALVE DISEASE 10:15 10:45 AM Management of Patients with Asymptomatic Aortic Valve Disease Active Monitoring of Aortic Valve Disease Multidisciplinary Team Approach to Patient Management Timothy Boyek, MD 10:45 11:15 AM Pre-op Evaluation for Cardiac Surgery The Importance of the H&P Assessing Perioperative Risk Patient-physician Collaboration in Setting Goals and Expectations Steven Weiss, MD, MBA 11:15 11:45 AM Update on TAVR Data From Long-term Follow-up Current Criteria for Patient Selection Reducing Risk for Stroke Post TAVR Prashanth Vallabhajosyula, MD, MS 11:45 AM 12:00 PM Q & A 12:00 12:30 PM Pick up Lunch 12:30 1:00 PM Case Presentations Mian A. Jan, MD, Hanna Ahmed, MD 1:00 1:15 PM Q & A HEART FAILURE 1:15 1:45 PM Inherited Cardiomyopathies ECG Recognition Role of Genetic Testing Determining Risk for SCD Anjali Owens, MD 1:45 2:15 PM New Pharmacologic Therapies for HF When to use Ivabradine LCZ696 and PARADIGM HF W. Clay Warnick, MD ARRHYTHMIA 2:15 2:45 PM Long QT Syndrome, Inherited & Acquired Scope of the Problem Genetics and LQTS Medications and LQTS Kurt Schillinger, MD, PhD 2:45 3:00 PM Q & A 3:00 3:15 PM Break 3:15 3:45 PM Left Atrial Occlusion Devices Review Outcomes of Protect AF Stroke Prevention in Patients With AF Criteria for Implantation Fermin Garcia, MD PREVENTION 3:45 4:15 PM Cardio-Renal Syndrome What do They Have in Common? Reduced GFR and Risk for CVD Mian A. Jan, MD, Ambereen M. Jan, MD 4:15 4:45 PM Diabetes and Heart Disease Impact on Morbidity & Mortality Challenges in Screening for CVD Christopher Bruno, DO 4:45 PM Adjourn

REGISTRATION FORM Current Advances in Cardiovascular Care 2016 If you are registering using your credit card, please register online at: www.penncmeonline.com and click on CME Activities/Live Events. Questions? Contact us at: Phone: 215-898-6400 or 215-898-8005 penncme@mail.med.upenn.edu Please note we are unable to accept faxed registration forms. Please print or type Name (First) (Last) Academic Degree Medical Specialty Affiliation (Hospital, Office, or Company) Address ( Affiliation or Home) City State Zip Phone Fax E-mail Registration Fee (pre-payment is required to be officially registered) $99 for Physicians $79 for Physician Assistants, Nurse Practitioners, Certified Registered Nurse Anesthetists $59 for Nurses and Healthcare Professionals $49 for Chester County Hospital and Penn Medicine employees, faculty and staff with a valid Chester County Hospital or Penn Medicine ID. Penn Medicine ID # Payment Method If you are paying by credit card, please register online at www.penncmeonline.com and click on CME Activities/Live Events. If you are paying by check, you may mail your completed registration form and check made payable to The Trustees of the University of Pennsylvania/CME to: Conference Coordinator, Perelman School of Medicine at the University of Pennsylvania, Office of Continuing Medical Education 150 Anatomy/Chemistry Building, 3620 Hamilton Walk 19104-6061 Do not include any credit card information on the registration form or email any credit card information Please Note: Walk-in registrants must bring payment to the program. Seating may be limited for walk-in registrants.

150 Anatomy/Chemistry Building 3620 Hamilton Walk 19104-6061 Current Advances in Cardiovascular Care 2016 A CME/CNE-Certified Course The Wyndham Garden Exton Valley Forge 815 North Pottstown Pike Exton, PA 19341