Turbocharging Mexico s Innovation Stephen Ezell VP, Global Innovation Policy ITIF. Mexico Innovation Week March 30, 2017

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Turbocharging Mexico s Innovation Economy Stephen Ezell VP, Global Innovation Policy ITIF Mexico Innovation Week March 30, 2017 @ITIFdc

About ITIF Independent, nonpartisan research and education institute focusing on intersection of technological innovation and public policy, including: Innovation and competitiveness IT and data Telecommunications Trade and globalization Life sciences, agricultural biotech, and energy Mission to formulate and promote policy solutions that accelerate innovation and boost productivity Ranked by University of Pennsylvania as top science and technology think tank in United States and number two in world 2

Today s Presentation 1 2 3 How Countries Can Best Maximize Innovation How Mexico Can Get Key Innovation Policies Right Turbocharging Life-Sciences Innovation in Mexico 3

Innovation Economics: The Race for Global Advantage Rob Atkinson Stephen Ezell Yale University Press September 2012 4

Get the 8 I s of Innovation Policy Right 1. Inspiration 2. Intention 3. Insight 4. Institutions 5. Investment 6. Incentives 7. Intellectual Property 8. International 5

Get the Innovation Triangle Right Business Environment Regulatory Environment Innovation/Technology Policy Environment 6

Business Environment 1. High levels of entrepreneurship 2. Access to risk/venture capital 3. Embrace dynamic churn and change (e.g. creative destruction) 4. Cultural willingness to experiment and take risks 5. Strong management skills in enterprises 7

Regulatory Environment 1. Transparency and rule of law 2. Protection of intellectual property (and other property rights) 3. Ease of starting a business 4. Pro-competition regulatory policies 5. Flexible labor policies 8

Innovation/Technology Policy Environment 1. Funding for research, especially commercially oriented research 2. Incentives to invest in R&D, capital equipment, workforce training 3. Universities strong not just in liberal arts but engineering 4. Supporting technology transfer from academia to industry 5. Strong STEM education system 9

The Distinct Nature of Innovation-Based Industries 1. They compete by inventing next-generation products and services. 2. They embody and depend on intellectual property. 3. They are characterized by very high initial fixed costs (e.g., R&D/design), but low marginal costs which 4. Means they need access to large global markets. 10

Today s Presentation 1 2 How Countries Can Best Maximize Innovation How Mexico Can Get Key Innovation Policies Right 3 Turbocharging Life-Sciences Innovation in Mexico 11

The Americas Top 3 How Does Mexico Rank on Global Innovation Indices? Overall 1. Finland 2. Sweden 3. United Kingdom 10. United States 25. Canada 40. Chile 41. Brazil 45. Colombia 46. Costa Rica 48. Peru 50. Mexico 56. Argentina 12

Key Innovation Priorities for Mexico 1. Increase investment in research and development. 2. Leverage tax policy to stimulate R&D and innovative activity. 3. Increase investment in education. 4. Continue to bolster and support entrepreneurship. 5. Strengthen IP rights. 6. Continue to embrace trade and FDI liberalization. 13

Increase Mexico s National R&D Intensity 4.50% R&D Investment as a Share of GDP 4.00% 3.50% 3.00% 2.50% 2.00% 48 th 1.50% 1.00% 0.50% 0.00% Colombia Uruguay Mexico Costa Rica Argentina South Africa Latin America & Caribbean India Europe & Central Asia (excluding high income) Brazil East Asia & Pacific (excluding high income) China Singapore United States Korea 14

Increase Government Funding of University Research $50 Government Funding of University Research (per capita) $45 $40 $35 $30 48 th $25 $20 $15 $10 $5 $0 Brazil Argentina Colombia South Africa Costa Rica Mexico Peru Chile India China Source: ITIF, Contributors and Detractors: Ranking Countries Impact on Global Innovation, 2016 15

Increase Industry-Funded University Research Average Industry Income Per Academic (US$ Thousands) Source: THE DataPoints THE data@timeshighereducation.com. 16

Effective Tax Policies Can Help Spur Mexican R&D Comparative R&D Tax Credit Generosity Source: We re 27 th! The United States Lags Far Behind in R&D Tax Credit Generosity 17

Effective Tax Policies Can Help Spur Mexican R&D Generous R&D tax credits (e.g., Brazil, China, India, Malaysia). Robust collaborative R&D tax credits (Chile, Thailand, Turkey). Patent boxes (China, Hungary). Sources: ITIF, Creating a Collaborative R&D Tax Credit, ITIF, Patent Boxes: Innovation in Tax Policy and Tax Policy for Innovation 18

Invest More in Human Capital/Education $9,000 Average Education Expenditure for Primary and Secondary Student $8,000 $7,000 $6,000 49 th $5,000 $4,000 $3,000 $2,000 $1,000 $0 Spain Malaysia Korea Poland Thailand Costa Rica Argentina Mexico Colombia Peru Source: ITIF, Contributors and Detractors: Ranking Countries Impact on Global Innovation, 2016 19

Increase the Number of Science Graduates 0.70 Science Graduates per 1,000 Citizens 0.60 0.50 0.40 54 th 0.30 0.20 0.10 0.00 Malaysia Turkey Costa Rica Chile Brazil Colombia Mexico Argentina Indoensia Source: ITIF, Contributors and Detractors: Ranking Countries Impact on Global Innovation, 2016 20

How Mexico Is Supporting Entrepreneurship Launched the National Entrepreneur Institute. Introduced a joint Entrepreneurship and Innovation Council to strengthen the North-American high-impact entrepreneur ecosystem. CONACYT University and Technology Transfer Centers Program. Universities increasingly embracing/teaching entrepreneurship. 21

Women Remain an Underutilized Innovation Resource 35% Total Early-Stage Entrepreneurial Activity, Select Countries 30% 25% 20% 15% 10% 5% 0% Ecuador Peru Bolivia Chile Guatemala Mexico Colombia Brazil Uruguay China Argentina Indonesia UK Costa Rica USA India Source: 2015/2016 Global Entrepreneurship Monitor Report Female Male 22

Encourage Entrepreneurship and Risk Taking 90% 80% Successful Entrepreneurship Enjoys A High Societal Status Latin American countries shown in orange. 70% 60% 50% 40% 30% 20% 10% 0% Source: 2015/2016 Global Entrepreneurship Monitor Report 23

Reform University Policies to Spur Innovation and Entrepreneurship Give academic researchers ownership rights of IP deriving from government-funded research (e.g., Bayh-Dole ). Give students rights to the IP they invent at universities. Increase permeability: Take faculty members commercial experiences into account in tenure decisions; allow faculty to suspend tenure to pursue commercialization opportunities. Support the development of university incubators. Develop university entrepreneurship rankings. 24

IPRs Are Vital to Innovation, As They: 1. Create incentives for domestic innovation. 2. Enable a virtuous cycle of innovation. 3. Induce knowledge spillovers that help others to innovate. 4. Promote the international diffusion of technology, innovation, and knowhow. 5. Boost domestic levels of exports, R&D, and FDI. 25

Strengthen Intellectual Property Rights Protections 2017 GIPC International IP Index Rankings Mexico 20 th of 45 Countries Source: U.S. Chamber of Commerce, International Intellectual Property Index 26

Leadership in Biotechnological Innovation Requires Robust IP Protection Source: Global Intellectual Property Center, IP-A Global Navigation Center for the Knowledge Economy 27

Mexico Leading the Charge for Trade Liberalization Source: The Economist; Moody s Analytics/Economy.com 28

Today s Presentation 1 2 3 How Countries Can Best Maximize Innovation How Mexico Can Get Key Innovation Policies Right Turbocharging Life-Sciences Innovation in Mexico 29

Why Life-Sciences Innovation Matters Helping citizens live longer, healthier lives generates economic benefits. Improvement in U.S. life expectancy from 1970 to 1990 added $2.8 trillion to U.S. productivity. This equaled $12,000 per U.S. citizen, per added year of life expectancy. Opportunity cost of missing work (especially for chronic diseases) Keeps many out of work, lowers productivity, contributes to absenteeism. Eliminating heart disease valued at $48 trillion, curing cancer $47 trillion; Alzheimer s disease will cost $1 trillion a year by 2050. 30

Mexico s Robust Life-Sciences Sector Mexican pharmaceutical industry Mexico has the 2nd largest biopharmaceutical market in Latin America and the 11th largest in the world. Proportion of GDP 1.2% Growth of 0.7% from 2007 Proportion of Manufacturing GDP 6.8% Significant manufacturing sector in Mexico Direct Jobs 86,277 37% linked to manufacturing Indirect Jobs 313, 605 Includes jobs in other companies from which the pharmaceutical industry buys goods or services Sector growth 4.3% Between 2007 and 2013 Economic units 718 Companies located mainly in Mexico City, Jalisco, Estado de México and Puebla. Multinational biopharmaceutical industry 20 of 25 Top multinational biopharmaceutical companies operate in Mexico Investment in R&D US$500m by 2025 Increase of US$160m from 2015 Biotechnology drugs 65% by 2030 Proportion of patent applications for new medicines Sources: Mexican Health Review 2015, Marketline, INEGI, COFEPRIS, Denue and CANIFARMA. Courtesy Fundacion IDEA. 31

How Mexico s Life-Sciences Sector Fares Globally Source: The Race for Biopharmaceutical Innovation: BCI Survey 2016 32

Increasingly Fertile Environment for Life-Sciences Innovation Pharmaceutical Patents Filed Through Patent Cooperation Treaty, 2000-2015 Source: WIPO; The Geneva Network 33

Increasingly Fertile Environment for Life-Sciences Innovation Absolute Number of Clinical Trials to Date, Global Comparison 2016 Source: Pugatch Consilium, Developing the Biotechnology Sector 34

Life-Sciences Innovation Strengths in Mexico A cost-competitive environment for life-sciences innovation. Competitive costs (% of savings) -35.9% R&D in biotechnology -31.5% Clinical trials -39.3% Product testing -14.4% Pharmaceutical manufacturing Increasingly skilled human capital base for biomedical research. Diverse ecology a platform for biomedical innovation. Source: The Geneva Network, ProMexico 35

Addressing Roadblocks to Regulatory Approval of Innovative Medicines Speeding patient access to innovative drugs vital for sector to realize its true innovation potential. Only 10% of drugs are approved and made available in public healthcare institutions. Source: The Geneva Network 36

Life-Sciences Innovation Opportunities for Mexico Improve clinical trial guidelines (e.g. research team changes means trials restarts; clarify ownership rules for clinical trial data). Greater enforcement of biopharmaceutical IP; fight piracy/counterfeiting. Enhance R&D collaboration between biopharmaceutical industry, research institutions, and universities. Public procurement system fragmented; prioritizes cost over value. Recognize that biopharmaceutical value creation comes from the R&D, not from the manufacturing. Set a goal of becoming a G20 life-sciences innovator. 37

Muchas Gracias! Stephen Ezell sezell@itif.org 202.465.2984 @ITIFdc