Elaine Wynn School

Dr. Garrett Reisman Golden Nugget Scholar

More than 230 graduating high school students have received: Ernesto Velezquez Four years of financial assistance for undergraduate careers Professional and peer mentoring Assistance with internships Opportunities for volunteerism Vocational assistance in pursuing career goals

2,300 educators honored

Peter Diamandis

X-Prize Foundation Projects

Progressive Automotive X-Prize Super-efficient Car

Archon Genomics X-Prize Human Genome Sequencing

Archon Genomics X-Prize Human Genome Sequencing The Genome 100

Google Lunar X-Prize Lunar Landing

X-Prize Lunar Landing

X-Prizes In Development Cancer X PRIZE Suite Energy X PRIZE Suite Global Entrepreneurship Healthcare

Quincy Jones

Quincy Jones Listen Up Foundation

Ca = Cancer P = Prostate CURE = All diseases

1993

2005

Real Progress More drugs in the pipeline than ever Increased federal funding for prostate cancer and other forms of cancer Accelerated development of better treatments Improved quality of life Fewer men are dying.

Ray Charles Count Basie & Frank Sinatra

Herbie Hancock Usher Bumps Blackwell Band

We Are the World

Giving as a Percentage of GDP United States 1.85 United Kingdom 0.84 France 0.32 Brazil 0.29 South Korea 0.18 Germany 0.13 India 0.09 China 0.05 Sources: Forbes (3/24/08) - McKinsey on Nonprofits - 2005

Biomedical Research Funding $100 $90 (Billions) $94 billion $80 $70 NIH Government 40% $60 $50 $40 $30 $20 $10 $37 billion Other Federal Support State & Local Govt. Philanthropy Pharmaceutical Firms Biotech Firms Medical Device Firms $0 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 Industry 57% Source: Moses H 3rd, et al. JAMA. 2005;294:1333-1342

Biomedical Research Funding $100 $90 (Billions) $94 billion $80 $70 NIH Government 40% $60 $50 $40 $30 $20 $10 $37 billion Source: Moses H 3rd, et al. JAMA. 2005;294:1333-1342 Other Federal Support State & Local Govt. Philanthropy Pharmaceutical Firms Biotech Firms Medical Device Firms $0 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 Philanthropy 3% Industry 57%

An organization dedicated to shortening the time to find cures and better treatments for the most deadly and debilitating diseases.

Record Giving in 2006 Charitable giving totals $260 billion/year in the U.S. Giving by foundations hit $40+ billion in 2006 setting a record (vs. $36.4 billion in 2005) Wealthy Americans committed $7 billion in 2006 (vs. $4.3 billion in 2005) 70,000+ foundations in the U.S. twice as many as in the 1990s 75%+ increase over a decade Source: WSJ July 8, 2006; NYT, April 3, 2007

Philanthropic Giving* As a Percent of GDP, 1995-2002 Percent of GDP 2.0 1.5 *Cash and other material gifts 1.0 0.5 0.0 U.S. Canada Netherlands France Britain Sweden Germany Japan Italy Source: The Economist

Foundation Giving Percentage of Grant Dollars by Destination 2005 Public Affairs/Society Benefit 11.2% Int'l Affairs, Dev. & Peace 3.6% Science & Technology 3.1% Social Sciences 1.2% Religion 2.5% Other 0.1% Arts and Culture 12.5% Education 24.0% Source: The Foundation Center Human Services 14.8% Health 20.8% Environment and Animals 6.3%

Pursuing Your Passion! Peter H. Diamandis, MD Chairman/CEO, X PRIZE Chairman/CEO, Zero-G

Parabolic Flight 15 Parabolas 1 Martian, 2 Lunar, 12 Zero 30 sec each total of 7+ minutes of weightlessness 1 hour of ground training 90 minute flight

G-Force One Regular Service from: McCarren/Las Vegas Orlando/Kennedy Space Center

Highlights 11-Year Start-up 170 flights (2004 2007) Over 5,000 people flown Over 750 math & science teachers flown Awarded the NASA Contract for training & research flights

Prof. Stephen Hawking in Weightlessness Giving the world s expert in gravity the experience of Zero Gravity

Space Adventures Orbital Flights

1919 Raymond Orteig puts up a $25,000 challenge. 9 Teams spent $400,000 to win the prize Underdog, 25 year old Lindberg wins! Within 18 months of his flight: Passenger traffic increased 30x # of aircraft increased 4x Aviation stocks soar to new heights 1927 Orteig Prize: New York - Paris

Ansari X PRIZE $10 Million prize purse Privately funded teams 3 person reusable spaceship 100 km altitude Two flights within 2 weeks Announced: May 18th, 1996 Won: October 4th, 2004

Ansari X PRIZE Teams ARCA Space Transport 26 teams from 7 nations spent over $100M to win the $10M purse DaVinci Project Canadian Arrow Rocketplane Armadillo Aerospace StarChaser Pablo DeLeon Mojave Aerospace Ventures Wins October 4, 2004 Mojave, California Scaled Composites SpaceShipOne

5.5 Billion Media Impressions Worth in Excess of $120 Million

Hallmark Attributes of Large Incentive Prize Competitions 1. High Leverage: Teams spend roughly 10 50 times the value of the purse Efficiency: You only pay the winner pay-for-performance Encourage Industry Development: Rather than give rise to a single solution, a prize gives rise to many solutions

Creation & Growth of a Philanthropic and Innovation Resource

Mission & Growth of XPF X PRIZE Board of Trustees Meeting Mission Statement: To bring about radical breakthroughs for the benefit of humanity New Board Members: Expanded Mission: Vision: Page, Musk, Venter, Kamen, Kurzweil, Huffington, Space 5 different verticals Change philanthropy Efficient & highly leveraged Build a valuable best practices prize organization

Five Prize Verticals Energy & Environment Life Sciences Global Development Education Exploration

Prize Methodology Prize Development Process Screening Discovery R&D Selection Ramp Implementation Competition Award Prize Selection Criteria Benefit to Humanity: Solving the problem will result in substantial public benefit There is public and political interest in the problem (or it can be generated) Prize Potential: There is a market / government bottleneck A difficult but achievable goal can be defined and can be won in 3-8 years The prize complements the XPF brand and portfolio Goals and rules are objective and simple to communicate Demonstrated performance wins prizes, not subjective judgment Prize Purse: A prize purse ($10M or greater) of sufficient size to encourage competitor investments can be procured Sponsors and donors are available to support competition and outreach Mobilization: The prize will mobilize teams, investors and sponsors There is the potential to create heroes and tell compelling stories Media coverage will drive public excitement and innovation adoption Markets and governments are likely to adopt, scale and sustain the innovation

Important Attributes Large Cash Purse ($10M >) Clear objective & simple rules Target areas that are stuck Define a problem, not a solution Attract maverick thinkers from across disciplines (worldwide) Change the paradigm of what is possible Make heroes out of the teams

Important Attributes Ideally are telegenic, open to media, to drive PR engine; Educate the public, get them excited and involved. Dial Degree of Difficulty based on parameters For an X PRIZE it is 3 to 8 years; Encourage taking intelligent risk!

Active X PRIZEs $10,000,000 Launched: 10.04.06 Vertical: Life Sciences Sequence 100 human genomes in 10 days; genomics.xprize.org $30,000,000 Launched: 09.13.07 Vertical: Exploration Land a robot on the moon, rove 500 meters and send back images; space.xprize.org Drop in a Low-res AXP Image $10,000,000+ Launch: 03.20.08 Vertical: Energy & Environment Build an affordable, desirable, manufacturable 100 MPGe car auto.xprize.org

X PRIZE Cup $10 Million Purse for the first team to: - Sequence 100 Human Genomes - In 10 days Purse funded by: Dr. Stewart & Marilyn Blusson Teams: 6 registered teams & another 4-6 in discussion

Archon X PRIZE -- Genome 100 Genome 100 the human face of personalized medicine celebrities, benefactors, and representatives of patient groups.

What is the Google Lunar X PRIZE? $30,000,000 purse $20M 1 st place $5M 2 nd place $5M in Performance Bonuses Open to world-wide competition Privately financed teams must: Land a rover on Moon Explore at least 500m of the lunar surface Return two packages of high definition video and imagery called Mooncasts Bonuses encourage: Roving further along the lunar surface Visiting man-made hardware Surviving a lunar night Diverse teams

Announcement Announced Sept 13, 07 at NextFest Stage presentations from: Larry Page, Buzz Aldrin Shana Dale (NASA); Elon Musk (SpaceX) 300 press in attendance 650+ registration requests from 60 countries received within 6 months >10 fully registered teams. First attempts expected within 3 years.

Progressive Automotive X PRIZE - Launch

Progressive Automotive X PRIZE Our goal: Inspire a new generation of clean, production-capable, superefficient (>100 MPGe) vehicles that help break our addiction to oil and stem the effects of climate change. Vehicle Classes Mainstream (4+ passengers, 4+ wheels, range 200 mi, etc.) Alternative (2+ passengers, 3+ wheels, range 100 mi, etc.) Overall Requirements Production-capability (safety, features, cost & plan) High fuel economy (> 100 MPGe) Low emissions (< 200 g/mi GHG) How to Win Qualify Race Meet overall requirements Fastest overall time in each class wins

Progressive Automotive X PRIZE - Launch Mayor Bloomberg 21 March 2008

The most critical tool for solving The most critical tool for solving Humanity s Grand Challenges any Challenges is the committed, passionate is the committed, passionate human mind. human mind.

Happy Birthday, Elaine!

Growing up in Chicago

With daughter Rashida

TRAIN - The Redstone Acceleration & Innovation Network Create and share information technology platforms Promote medical record & biological material databases Encourage open-source approach to intellectual property Share case studies in novel disease research approaches Create a best-approach guide to selecting, funding and reviewing scientific research Support collaborations, coalitions, mergers and joint ventures among disease groups

TRAIN Lance Armstrong Foundation Cystic Fibrosis Foundation Cure Autism Now Prostate Cancer Foundation Myelin Repair Foundation Michael J. Fox Foundation Parkinson s Action Network Susan G. Komen Breast Cancer Foundation Multiple Myeloma Research Foundation ALS Therapy & Development Foundation Institute for One World Health Accelerated Cure Foundation Pacific Vascular Research Foundation Alliance for Aging Research Children s Neurobiological Solutions Foundation Dr. Susan Love Research Foundation The Epilepsy Project The National Neurofibromatosis Foundation Foundation for Fighting Blindness National Alliance for Autism Research JDRF Alpha-1 Foundation Huntington s Disease Research Foundation Autism Speaks ABC2 International AIDS Vaccine Initiative

America s Cup

Ted Turner s Courageous

Nelson Mandela

Bill Milliken