DARPA-SN Molecular Scaffold Design Collective (MSDC) Frequently Asked Questions (FAQs) as of 4/6/18

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DARPA-SN-18-47 Molecular Scaffold Design Collective (MSDC) Frequently Asked Questions (FAQs) as of 4/6/18 28Q: Under Section IV.C. Proposal Due Date and Time, what is meant by some parts of the submission process may take from one business day to one month to complete? 28A: Some parts of the submission process may take from one business day to one month to complete. The DUNS number is used as the contractor identification code for all Government procurement-related activities. Requesting a DUNS number may take at least 1 business day. Requesting a TIN may take from 1 business day to 1 month depending on the method (online, fax, mail). New registrations in SAM can take an average of 7-10 business days to process. In addition, DARPA's preferred method of proposal submission, electronic upload, must be completed via the DARPA Submission website https://baa.darpa.mil/. Since proposers may encounter heavy traffic on the web server, DARPA discourages waiting until the day proposals are due to request an account and/or upload the submission. Please carefully review DARPA-PA-18-01 for additional information on submission requirements and instructions. 27Q: What is the appropriate length of the Technical and Management Volume? 27A: Per the Disruptioneering Proposal Template Volume 1 (provided as an attachment to DARPA-PA-18-01), Technical and Management Volumes in response to a Disruption Opportunity shall not exceed a maximum of 8 pages. Please carefully review this Attachment for a complete list of requirements, and note that use of the template is mandatory for proposals submitted in response a Disruption Opportunity. 26Q: What is the definition of a nontraditional defense contractor? 26A: Per the Disruptioneering Program Announcement DARPA-PA-18-01: As defined by 10 U.S.C. 2302(9), a nontraditional defense contractor, with respect to a procurement or with respect to a transaction authorized under section 2371b of this title, means an entity that is not currently performing and has not performed, for at least the one-year period preceding the solicitation of sources by the Department of Defense for the procurement or transaction, any contract or subcontract for the Department of Defense that is subject to full coverage under the cost accounting standards prescribed pursuant to section 1502 of title 41 and the regulations implementing such section. In accordance with 48 CFR 9903.201-2 - Types of CAS coverage, full coverage under cost accounting standards applies to contractor business units that (1) Receive a single CAS-covered contract award of $50 million or more; or (2) Received $50 million or more in net CAS-covered awards during its preceding cost accounting period. 25Q: How should the proposal be submitted? 25A: As detailed in Section 5 of the Disruptioneering Program Announcement DARPA- PA-18-01, responses shall be submitted through one of the following methods: (1) electronic upload to https://baa.darpa.mil/ (DARPA-preferred); or (2) direct mail/handcarry. Proposers must submit all parts of their submission package using the same method. DARPA-SN-18-47 FAQs 1

DARPA will acknowledge receipt of complete submissions via email and assign identifying numbers that should be used in all further correspondence regarding those submissions. If no confirmation is received within two business days, please contact DARPA-PA-18-01@darpa.mil to verify receipt. 24Q: The effective start date of the program would conflict with my new job start date. Is it possible for me to apply now, and postpone the start date of the grant until after the start date of my new job, if my application is selected. 24A: As detailed in the Special Notice, the program has an aggressive schedule that will require the period of performance of all performers to align. For this reason, requests to delay the start of work for individual performers cannot be accommodated. Further, a proposal selected for award will be made to the proposing organization. 23Q: The cost volume and price summary spreadsheet templates only include direct costs, such as direct labor, materials and equipment, travel, and ODCs. Are we supposed to include typical indirect costs in our proposal, such as fringe, overhead, and fee? If so, are there updated templates that include indirect cost elements? If not, is there some other way we should include those costs, such as using our fully burdened labor rates as our direct labor rates? 23A: Proposers need only provide the requested cost and pricing data in the Vol. 2 Price Volume and Volume 2 Price Summary Spreadsheet. Proposers may provide additional cost or pricing data to support their proposed price. The Government expects proposing organizations may include indirect costs and profit as part of their price for their Phase I and Phase II proposal submission. The Government anticipates that the indirect costs and profit, if proposed, would be added to the direct labor rates and other direct costs in accordance with an organization s accounting and estimating practices. For example, the direct labor rates proposed in the Price Summary Spreadsheet may include, or be burdened with, fringe, overhead, G&A and profit, when appropriate. 22Q: Is DARPA facilitating teaming? 22A: DARPA is not facilitating the formation of teams for this program. Teaming is at the discretion of the proposer and encouraged if necessary to the proposed work. Please carefully review the stated objectives and goals of the program. Specific content, communications, networking, and team formation are the sole responsibility of the participants. 21Q: Is my topic of interest? 21A: If you believe your research is within the scope the Special Notice, you are encouraged to submit a proposal. Please carefully read the Special Notice for information on the research project objectives and scope of the opportunity. If you have a specific technical question that can be shared publicly via the FAQ, please submit it to MSDC@darpa.mil. 20Q: How many awards are anticipated? 20A: As stated in the Disruptioneering Opportunity announcement, Multiple awards are anticipated. The amount of resources made available under each DO SN issued under DARPA-SN-18-47 FAQs 2

DARPA-PA-18-01 will depend on the quality of the proposals received and the availability of funds. 19Q: Would it be acceptable to submit a proposal with costs significantly under the ceiling of $1M? 19A: As stated in the SN, Proposers must provide a technical and programmatic strategy that conforms to the entire 18-month program schedule and presents an aggressive plan to fully address all program goals, metrics, milestones and deliverables. Projects with costs under the ceiling that are able to meet this requirement will be considered. 18Q: Where should profit be included; in the price summary and/or price volume? 18A: Please see the response to 24Q. The Government anticipates that the indirect costs and profit, if proposed, would be added to the direct labor rates and other direct costs in accordance with an organization s accounting and estimating practices. For example, the direct labor rates proposed in the Price Summary Spreadsheet may include, or be burdened with, fringe, overhead, G&A and profit, when appropriate. 17Q: Are labor category descriptions required for submission? If yes, how should this information be submitted? 17A: Yes. Labor category descriptions should be provided in the Volume 2: Price Volume. 16Q: If there is no 1/3 proposer cost share, is the Total Price amount entered into the "Government Share" cells, or in the "Recipient Share" cells? 16A: Government Share 15Q: Please confirm Direct Labor rates should be fully burdened (loaded), to include G&A and overhead. 15A: Direct Labor rates may be fully burdened (loaded) to include applicable indirect costs, such as G&A and overhead. See question 24 herein. 14Q: Is 1/3 cost share a requirement if significant participation is performed by a Small Business? If the answer is no, does 1/3 cost share need to be addressed in the price proposal for compliance? 14A: Cost share is not required if a small business is participating to a significant extent in the proposed research effort. Proposers must provide the responses required in the Volume 2: Price Volume Template under paragraph 9 and any supporting documentation to verify that an organization is a small business. 13Q: Does registration in SAM as a Small Business suffice for documentation for a Small Business entity? If no, please provide examples for small business documentation. 13A: Yes. Proposers should ensure that they are registered in SAM under NAICS Code: 541715; Small Business Size: 1500. This is the assigned NAICS for DARPA-PA-18-01. DARPA-SN-18-47 FAQs 3

12Q: In the context of Volume 3, Item #4, "Novelty of Proposed Work," does "proposed work" refer to the complete solution? What if a partial/or portion of the solution has been proposed? 12A: If any part of the proposed work has been submitted to any other Government solicitation, it should be documented in item #4. All proposals must address all of Research Project Objectives identified in the Special Notice. Proposals that fail to address all of the objectives may not be considered for funding. 11Q: As currently written, Appendix A restricts a nonprofit university from applying to the PA as lead institution unless it provides at least one third of total cost (Appendix A condition (C)). NDAA of 2018 expands the use of OTs for projects that involve nonprofit research institutions by inserting or nonprofit research institution after defense contractor. Will DARPA revise PA-18-01 Appendix A condition (A) to include the above amendment? Do nonprofit universities need to provide 1/3 cost share? 11A: This is correct. Under the National Defense Authorization Act for Fiscal Year 2018, an amendment to Section 2371b(d)(1)(A) of title 10, United States Code, inserted or nonprofit research institution after defense contractor. As a result of this amendment, nonprofit research institutions, which include nonprofit universities, are not required to provide one third cost share in order to be awarded an Other Transaction for prototype project agreement under 2371b. Additionally, organizations that team with a nontraditional defense contractor or nonprofit research institution may not be required to provide one third cost share if the nontraditional defense contractor or nonprofit research institution is participating to a significant extent in the proposed research project. 10Q: If we can meet a milestone prior to the month indicator in the Special Notice should we include within our proposal the actual planned completion month and associated payment amount? 10A: Yes, proposers may suggest changes to the anticipated milestone schedule. Ultimately, the final milestone plan will be subject to DARPA review and approval and finalized during negotiations. 9Q: If a 1/3 cost-share is required, are the total award values provided in the Special Notice inclusive or exclusive of the 1/3 cost-share? 9A: Total awards will not exceed $1,000,000. This includes Government funding and performer cost share (if required). 8Q: What types of materials are of interest to this program? 8A: MSDC is interested in performers who can address many potential areas of DoD relevance so we can offer government partners flexibility and creativity in terms of what we explore in the program. Capabilities are more important than specific systems you ve worked on (or think might be relevant) for energetics. 7Q: Will a background in energetic materials disqualify me as an academic research participant? 7A: No, experience with energetics is fine. The critical piece is being able to synthesize interesting structures that might be viable, but never before used, for pre-energetic materials. DARPA-SN-18-47 FAQs 4

6Q: What is the deadline for the academic participants? 6A: Per DARPA-SN-18-47, proposals are due by April 26, 2018. 5Q: Does my idea about synthesizing XYZ molecule serve your purpose stated in the SN? 5A: The MSDC program is focused on developing new molecules that might have relevance to DoD energetics needs. We are not providing specific guidance for a given molecular system prior to the proposal review. 4Q: Is there an incumbent contract or contractor associated to the requirement? 4A: There are no incumbent requirements. Please refer to DARPA-PA-18-01 and the SN for eligibility information. 3Q: What are the scientific goals and how might we plan to approach the submission? 3A: Synthetic methods that are of most interest to the program include those that enable scalable syntheses and control of features such as stereochemistry. The proposal should demonstrate the uniqueness and strength of the selected approaches relative to the properties described in the SN. Proposals do not need to identify specific molecules, but rather demonstrate synthetic capability. 2Q: Are U.S. permanent residents (green card holders) eligible to attend the meetings? 2A: Meeting attendance is restricted to U.S. citizens only, however, program participation generally is unrestricted. 1Q: I am really interested in applying to the MSDC program. Are you available to get your advice and discuss briefly some details about the proposal? 1A: Calls are not being held during the solicitation phase. If you have specific questions, you can email them to MSDC@darpa.mil. DARPA-SN-18-47 FAQs 5