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Medical Evacuations from Operation Iraqi Freedom/Operation New Dawn, Active and Reserve Components, U.S. Armed Forces, 23-211 From January 23 to December 211, over 5, service members were medically evacuated from the Operation Iraqi Freedom (OIF)/Operation New Dawn (OND) theater of combat operations to a medical treatment facility outside of theater. During the period, the numbers and underlying causes of medical evacuations sharply varied in relation to the numbers of deployed service members and the natures of ongoing military operations. There were nearly five times as many medical evacuations for disease and non-battle injuries than for battle-related conditions. The majority of medical evacuations (87%) occurred among males; the major causes of medical evacuations differed among male and female deployers. Based on these findings, force health protection policies and practices should be tailored to the characteristics of the deployed force and the nature of the military operation. from March 23 to December 211, over 2 million U.S. service members deployed one or more times in support of military operations in southwest Asia. In Iraq, Operations Iraqi Freedom (OIF) and New Dawn (OND) occurred sequentially from 19 March 23 through 31 August 21 and 1 September 21 through 31 December 211, respectively. In wartime theaters of operations such as Iraq, most medical care is provided by deployed military medical personnel; however, some injuries and illnesses require medical management outside the operational theater. In such cases, affected individuals are usually transported by air to a fixed military medical facility in Europe or the United States. At the fixed facility, they receive the specialized, technically advanced, and/or prolonged diagnostic, therapeutic, and rehabilitation care required. Medical air transports ( medical evacuations ) are costly and generally indicative of serious medical conditions. Some serious medical conditions are directly related to participation in or support of combat operations (e.g., battle wounds); many others are unrelated to combat and may be preventable. The objectives of this report are to compare the natures, numbers, and trends of conditions for which male and female military members were medically evacuated from the OIF/OND theater during the entire campaign. METHODS The surveillance period was 1 January 23 to 31 December 211. The surveillance population included all members of the active and reserve components of the U.S. Army, Navy, Air Force, Marine Corps, and Coast Guard who were evacuated during the surveillance period from the OIF/ OND theater of the U.S. Central Command (CENTCOM) area of responsibility (AOR) to a medical treatment facility outside the CENTCOM AOR. Evacuations were included in analyses if the affected service member had at least one inpatient or outpatient medical encounter in a permanent military medical facility in the U.S. or Europe within ten days after the evacuation date. Records of all medical evacuations conducted by the U.S. Transportation Command (TRANSCOM) are routinely provided for health surveillance purposes to the Armed Forces Health Surveillance Center (AFHSC) via the Office of the Assistant Secretary of Defense for Health Affairs. Medical evacuations included in the analyses were classified by the causes and natures of the precipitating medical conditions (based on information reported in relevant evacuation and medical encounter records). First, all medical conditions that resulted in evacuations were classified as battle injuries or non-battle injuries and illnesses (based on entries in an indicator field of the TRANSCOM evacuation record). Evacuations due to non-battle injuries and illnesses were sub-classified into 18 illness/injury categories based on International Classification of Diseases (ICD-9-CM) diagnostic codes reported on records of medical encounters after evacuation. For this purpose, all records of hospitalizations and ambulatory visits from five days prior to ten days after the reported date of each medical evacuation were identified. In most cases, the primary (first-listed) diagnosis for either a hospitalization (if one occurred) or the earliest ambulatory visit after evacuation was considered indicative of the condition responsible for the evacuation. However, if the first-listed diagnostic code specified the external cause (rather that the nature) of an injury (ICD-9-CM E- code) or an encounter for something other than a current illness or injury (e.g., observation, medical examination, vaccination [V-code]), then secondary diagnoses that specified illnesses and injuries (ICD-9-CM 1-999) were considered the likely reasons for the subject evacuations. RESULTS During the nearly nine-year period of the OIF/OND campaign, 5,634 medical evacuations of service members from OIF/ OND were followed by at least one medical encounter in a fixed medical facility outside the operational theater. Overall, nearly seven times more males (n=44,258) than females (n=6,376) were medically evacuated (Table 1). Of all medical evacuations, 17.7 percent were considered battle injury-related Page 18 MSMR Vol. 19 No. 2 February 212

No. of medical evacuations FIGURE 1. Medical evacuations of U.S.service members from OIF/OND, by month, January 23- December 211 1,4 1,2 1, 8 6 4 OIF begins Major combat operations end 1st battle of Fallujah 2nd battle of Fallujah Operation Lightning: antiinsurgent crack down Troop surge begins Troop surge peaks Troop surge ends Disease, non-battle injury OIF ends; OND begins OND ends 2 Jan 23 Mar 23 May 23 Jul 23 Sep 23 Nov 23 Jan 24 Mar 24 May 24 Jul 24 Sep 24 Nov 24 Jan 25 Mar 25 May 25 Jul 25 Sep 25 Nov 25 Jan 26 Mar 26 May 26 Jul 26 Sep 26 Nov 26 Jan 27 Mar 27 May 27 Jul 27 Sep 27 Nov 27 Jan 28 Mar 28 May 28 Jul 28 Sep 28 Nov 28 Jan 29 Mar 29 May 29 Jul 29 Sep 29 Nov 29 Jan 21 Mar 21 May 21 Jul 21 Sep 21 Nov 21 Jan 211 Mar 211 May 211 Jul 211 Sep 211 Nov 211 (Table 1). Not surprisingly, the numbers of evacuations for battle injuries varied in relation to the number of deployed service members (e.g., during troop surges compared to other periods) and the natures, locations, and intensities of ongoing combat operations (Figure 1). For example, there were spikes in battle-related evacuations from OIF/OND in April 23, April 24, and November 24 and another rise in April-May 27 (Figure 1). During every month of the nine year period, there were more medical evacuations for disease and non-battle injuries than TABLE 1. Numbers and proportions of medical evacuations from OIF/OND by major categories of illnesses and injuries, January 23-December 211 Total Total male Total female Diagnostic category (ICD-9-CM) No. % No. % No. % (from TRAC2ES records) 8,944 17.7 8,764 19.8 18 2.8 (71-739) 8,257 16.3 7,37 16.7 887 13.9 Non-battle injury and poisoning (8-999) 7,542 14.9 6,957 15.7 585 9.2 (29-319) 5,892 11.6 4,942 11.2 95 14.9 Signs, symptoms, ill-defi ned conditions (78-799) 5,65 1. 4,181 9.4 884 13.9 Nervous system (32-389) 2,684 5.3 2,375 5.4 39 4.8 Digestive system (52-579) 2,592 5.1 2,32 5.2 29 4.5 Genitourinary system (58-629, except breast) 1,794 3.5 1,252 2.8 542 8.5 Circulatory system (39-459) 1,512 3. 1,384 3.1 128 2. Other (V1-V82, except pregnancy-related) 1,62 2.1 88 2. 182 2.9 Neoplasms (14-239) 1,6 2. 755 1.7 251 3.9 Skin and subcutaneous tissue (68-79) 98 1.9 842 1.9 138 2.2 Respiratory system (46-519) 882 1.7 73 1.6 152 2.4 Infectious and parasitic diseases (1-139) 753 1.5 686 1.6 67 1.1 Endocrine, nutrition, immunity (24-279) 616 1.2 491 1.1 125 2. Breast disorders (61-611) 52 1. 117.3 385 6. Pregnancy and childbirth (63-679, relevant V codes) 268.5. 268 4.2 Congenital anomalies (74-759) 161.3 143.3 18.3 Hematologic disorders (28-289) 122.2 87.2 35.5 Totals 5,634 44,258 6,376 for battle-related injuries; overall during the period, there were nearly five times as many medical evacuations for non-battle as for battle-related conditions (Table 1, Figure 1). During the surveillance period, four categories of illnesses and non-battle injuries accounted for a majority (52.8%) of all evacuations. Musculoskeletal disorders, primarily affecting the back and knee, accounted for approximately one of every six (16.3%) evacuations; non-battle injuries, primarily sprains and fractures of extremities, accounted for approximately one of seven (14.9%) evacuations; mental disorders, most frequently adjustment reactions, mood disorders, anxiety disorders, and post-traumatic stress disorder (PTSD), accounted for approximately one of nine (11.6%) evacuations; and signs, symptoms and ill-defined conditions (more than one-fourth related to the respiratory system) accounted for one of ten (1.%) evacuations (Table 1). There were differences in the conditions that resulted in medical evacuations of male and female deployers. Of all medical evacuations of males throughout the period (n=44,258), the most frequent causes were battle injuries (19.8%), musculoskeletal disorders (16.7%), non-battle injuries (15.7%), and mental disorders (11.2%). In contrast, the most frequent February 212 Vol. 19 No. 2 MSMR Page 19

FIGURE 2. Proportions of medical evacuations, by major categories of illness/injury (ICD-9-CM), by gender, OIF/OND, U.S. Armed Forces, January 23- December 211 2 8. 18 16 14 12 1 8 6 4 2 Male Female Ratio M:F 7. 6. 5. 4. 3. 2. 1. Ratio of proportions, male:female Non-battle injury/poisoning Digestive system Signs/symptoms/ill-defined Respiratory system Circulatory system Genitourinary system (except breast disorders) Skin/subcutaneous tissue Neoplasms Nervous system Pregnancy/childbirth Infectious/parasitic diseases Endocrine, nutrition, immunity Congenital anomalies Hematologic disorders Other (except pregnancy-related) Breast disorders. causes of medical evacuations of females during the period (n=6,376) were mental disorders (14.9%), musculoskeletal disorders (13.9%), signs, symptoms, and ill-defined conditions (13.9%), and nonbattle injuries (9.2%) (Table 1, Figure 2). Among both males and females, adjustment reaction was the most frequent specific diagnosis (3-digit diagnosis code of ICD-9-CM) during initial medical encounters after evacuations. Adjustment reactions accounted for relatively more of the total evacuations of females (n=37; 5.8%) than males (n=2,; 4.5%). Among males, back and joint-related conditions specifically, intervertebral disc disorders (n=1,69; 3.6%), other and unspecified disorders of joint (e.g., knee problems) (n=1,524; 3.4%), and other and unspecified disorders of back (n=1,196; 2.7%) were the second, third, and fourth most frequent diagnoses among medical evacuees. The fifth most frequent diagnosis among males was symptoms involving the respiratory system and other chest symptoms (n=1,167; 2.6%) (data not shown). Among females, other disorders of the breast (n=34, 5.3%), other and unspecified disorders of joints (e.g., knee problems) (n=236, 3.7%), episodic mood disorders (n=233, 3.7%), and other symptoms involving the abdomen and pelvis (n=195, 3.1%) were the next most frequent diagnoses among medical evacuees (data not shown). Among OIF/OND male participants, the proportion of medical evacuations attributable to battle injuries declined from approximately 29 percent in 26 and 27 to 5 percent in 211 (Figure 3). In contrast, the proportion of medical evacuations attributable to mental disorders sharply increased from 7.1 percent in 23 to 2.9 percent in 21 then declined slightly to 17.6 percent in 211 (Figure 3). Among female participants, the proportion of medical evacuations attributable to battle injuries remained low compared to males with a peak at 5.5 percent in 24 followed by a decrease to under 2 percent from 28 to 211 (Figure 4). The relative proportion of medical evacuations due to mental disorders among females increased sharply from 7.4 percent in 23 to 26.6 percent in 21 (Figure 4). EDITORIAL COMMENT A previous MSMR report estimated that during a 12-month deployment to combat operations in Iraq and Afghanistan, approximately four percent of Army, two percent of Marine Corps, and one percent of the other services members were medically evacuated for any reason. 1 The relatively low likelihood of medical evacuation suggests that most deployers were sufficiently healthy and fit, and received the medical care in theater necessary, to successfully complete their OIF/OND assignments. This analysis extends the findings of previous reports on medical evacuations from OIF/OND. It documents that the numbers and underlying causes of medical evacuations from OIF/OND sharply varied in relation to the numbers of deployed service members and the natures of ongoing military operations. The report also documents differences in the predominant causes of medical evacuations among male and female deployers. The findings enforce the need to tailor force health protection policies, training, supplies, equipment, and practices based on characteristics of the deployed force (e.g., combat versus support; male versus female) and the nature of the military operations (e.g., combat versus humanitarian assistance). There are limitations to the analysis reported here that should be considered Page 2 MSMR Vol. 19 No. 2 February 212

FIGURE 3. Proportions of medical evacuations for selected diagnostic categories among males, OIF/OND, U.S. Armed Forces, January 23-December 211 FIGURE 4. Proportions of medical evacuations for selected diagnostic categories among females, OIF/OND, U.S. Armed Forces, January 23-December 211 3 25 2 15 1 5 Non-battle injury and poisoning Signs, symptoms and ill-defined conditions 3 25 2 15 1 5 Non-battle injury and poisoning Signs, symptoms and ill-defined conditions Genitourinary system Breast disorders 23 24 25 26 27 28 29 21 211 23 24 25 26 27 28 29 21 211 when interpreting the results. For example, assessments of trends were based on numbers of medical evacuations per month or year; as such, variations in the numbers of deployed troops (i.e., the population at risk of medical evacuation) over time were not factored in the analysis. Because the numbers of service members deployed to OIF/OND significantly varied during the period, trends of numbers of medical evacuations do not directly reflect changes in other risk factors for medical evacuation over time. Also, direct comparisons of numbers and proportions of medical evacuations by cause, as between operational theaters or between males and females, can be misleading; for example, such comparisons do not account for differences between the groups in other characteristics (e.g., age, grade, military occupation, locations, and activities while deployed) that are significant determinants of medical evacuation risk. Also, for this report, most causes of medical evacuations were estimated from primary (first-listed) diagnoses that were recorded during hospitalizations or initial outpatient encounters after evacuation. In some cases, clinical evaluations in fixed medical treatment facilities after medical evacuations may have ruled out serious conditions that were clinically suspected in the theater. For this analysis, the causes of such evacuations reflect diagnoses that were determined after evaluations outside of the theater rather than diagnoses perhaps of severe disease that were clinically suspected in the theater. To the extent that this occurred, the causes of some medical evacuations may seem surprisingly minor. This reports documents that, throughout OIF/OND (even during periods of the most intense combat), most medical evacuations were not directly related to battle injuries. Overall, approximately four of every five medical evacuations were due to illnesses and non-battle injuries; and of these, more than one-half were due to musculoskeletal disorders (16.3%), non-battle injuries (14.9%), mental disorders (11.6%), and signs, symptoms, and ill-defined conditions (1.%). In addition, this report documents that the proportions of medical evacuations due to mental disorders and battle injuries were not closely temporally related. For example, since 27 among both male and female participants, the proportion of medical evacuations due to battle injuries sharply decreased while the proportion due to mental disorders increased (Figures 3, 4). The recent increase in mental disorderrelated evacuations from Iraq may reflect, at least in part, increased awareness of, concern regarding, and health care resources dedicated to detecting and clinically managing psychological, stress-related disorders (e.g., PTSD, depression, suicide ideation) among deployers. In summary, during the entirety of the campaign in Iraq, more than 5, U.S. service members were medically evacuated. Throughout the period, there were many more medical evacuations for illnesses and non-battle injuries than for battle injuries; also, the major causes of medical evacuations differed among male and female deployers. Previous reports have documented that relatively large proportions of service members who are evacuated for illnesses (including musculoskeletal and mental disorders) during deployments had medical encounters for the same or closely related conditions shortly before deploying. 1 Further analyses should identify conditions among male and female service members that are most likely to recur or worsen during, and require medical evacuation from, combat-related deployments. REFERENCES 1. Armed Forces Health Surveillance Center. Medical evacuations from Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF), active and reserve components, U.S. Armed Forces, October 21-September 29. Medical Surveillance Monthly Report (MSMR).17(2):2-7. February 212 Vol. 19 No. 2 MSMR Page 21

Surveillance Snapshot:Medical Evacuations from Operation Enduring Freedom(OEF), Active and Reserve Components, U.S. Armed Forces, October 21-December 211 Medical evacuations a of U.S.service members from OEF (Afghanistan), by month, October 21- December 211 35 3 OEF begins Operation Kanjar begins 2 nd troop surge begins Insurgent attacks peak; Operation Hamkari begins Disease, non-battle injury No. of medical evacuations 25 2 15 1 st troop surge begins 1 5 Oct 21 Jan 22 Apr 22 Jul 22 Oct 22 Jan 23 Apr 23 Jul 23 Oct 23 Jan 24 Apr 24 Jul 24 Oct 24 Jan 25 Apr 25 Jul 25 Oct 25 Jan 26 Apr 26 Jul 26 Oct 26 Jan 27 Apr 27 Jul 27 Oct 27 Jan 28 Apr 28 Jul 28 Oct 28 Jan 29 Apr 29 Jul 29 Oct 29 Jan 21 Apr 21 Jul 21 Oct 21 Jan 211 Apr 211 Jul 211 Oct 211 a Methodology is the same as used for the medical evacuations from OIF/OND found on page 18. From October 21 to December 211, there were 19,437 medical evacuations of service members from Operation Enduring Freedom (OEF) that were followed by at least one medical encounter in a fixed medical facility outside the operational theater. During every month of the period, there were more medical evacuations for conditions not directly related to battle than for battle-related injuries; overall, 23.4 percent of evacuations were considered battle injury-related. Total medical evacuations increased in 29 following the surge in the number of service members deployed to Afghanistan. Since then, the numbers of evacuations per month have remained higher than pre-surge numbers, particularly in non-battle-related evacuations. Battle-injury evacuations tended to increase during the warmer months, presumably due to the impact of weather conditions on the natures, locations, and intensity of ongoing combat operations. For example, there were spikes in battle-related evacuations from OEF in August 29, June through October 21, and June through September 211. Page 22 MSMR Vol. 19 No. 2 February 212