Departmental Grants Manager (Duke applicants only, MUST SIGN THIS FORM!): Name: Phone:

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Joint UNC-Duke CFAR PrEP Application Coversheet Duke University co-principal Investigator: UNC CFAR co-principal Investigator (including middle initial): Title of Project: Funded Period: 3/15/2017-3/14/2018 Budget: (total Direct Costs) $100,000 Proposal Contains: YES NO Human Subjects research Research exempt Vertebrate animals research Date Submitted (due date: February 15, 2018): Duke University co-pi s Address and Contact Information: PI Name: Position (faculty rank): Address: Phone: Email: UNC CFAR co-pi s Address and Contact Information: PI Name: Position (faculty rank or equivalent): Address: Phone: Email: Departmental Grants Manager (Duke applicants only, MUST SIGN THIS FORM!): Name: Phone: Email:

Please indicate your faculty rank below Duke University co-pi Post-doc or Fellow with Faculty offer (if funded, requires a CFAR Mentoring Plan) Assistant Professor (if funded, requires a CFAR Mentoring Plan) Associate or Full Professor Previous CFAR Funding? Yes No If yes, please answer the following questions about the previous Award: Title: Date of Award: Publications resulting from Award: Funding resulting from Award: How is this proposed research different from the previous Award? UNC CFAR co-pi Post-doc or Fellow with Faculty offer (if funded, requires a CFAR Mentoring Plan) Assistant Professor (if funded, requires a CFAR Mentoring Plan) Associate or Full Professor FHI 360 or RTI PI (not UNC-based, if funded, requires a CFAR Mentoring Plan) Previous CFAR Funding? Yes No Please specify: If yes, please answer the following questions about the previous Award: Title: Date of Award: Publications resulting from Award: Funding resulting from Award: How is this proposed research different from the previous Award?

Self-reporting of CFAR user Category for the NIH Required by the NIH Duke University co-pi Indicate the user category that applies, below. *All CFAR users will fall into one of these four categories. 1-NIH AIDS PI Individuals who have ever been the PI on an R01 equivalent grant in HIV/AIDS (R01 equivalents include R01, R23, R29, R37 and, after 2008, DP2) 2-NIH PIs being brought into AIDS research: Individuals who are or have ever been the PI on an R01 equivalent grant, but never in HIV/AIDS 3-AIDS-research Pipeline: NIH New Investigators, An NIH definition that encompasses individuals who have received funding as a PI directly from NIH*, but not yet at the R01 equivalent level. 4-AIDS-research Pipeline: CFAR Users who have not yet received direct funding from NIH** as PI or Co-PI funding on any NIH grant mechanism. **Individuals whose only NIH funding at the PI or PD level has come indirectly from NIH, for example via an NIH CFAR Administrative Supplement, fall into Category 4. *Some CFAR users will also fall into one of these categories. Please check all that apply. Developmental Core Special Emphasis. Recipients of Developmental Core research funding, mentoring, and/or other services Developmental Core Special Emphasis. Recipients of NIH CFAR administrative supplements NIH Special Emphasis: Members of underrepresented groups in AIDS research. These include African-Americans, Hispanics, American Indians, Alaska natives, native Hawaiians, and Pacific Islanders NIH Special Emphasis. Women UNC CFAR co-pi Indicate the user category that applies, below. *All CFAR users will fall into one of these four categories. 1-NIH AIDS PI Individuals who have ever been the PI on an R01 equivalent grant in HIV/AIDS (R01 equivalents include R01, R23, R29, R37 and, after 2008, DP2) 2-NIH PIs being brought into AIDS research: Individuals who are or have ever been the PI on an R01 equivalent grant, but never in HIV/AIDS 3-AIDS-research Pipeline: NIH New Investigators, An NIH definition that encompasses individuals who have received funding as a PI directly from NIH*, but not yet at the R01 equivalent level. 4-AIDS-research Pipeline: CFAR Users who have not yet received direct funding from NIH** as PI or Co-PI funding on any NIH grant mechanism. **Individuals whose only NIH funding at the PI or PD level has come indirectly from NIH, for example via an NIH CFAR Administrative Supplement, fall into Category 4.

*Some CFAR users will also fall into one of these categories. Please check all that apply. Developmental Core Special Emphasis. Recipients of Developmental Core research funding, mentoring, and/or other services Developmental Core Special Emphasis. Recipients of NIH CFAR administrative supplements NIH Special Emphasis: Members of underrepresented groups in AIDS research. These include African-Americans, Hispanics, American Indians, Alaska natives, native Hawaiians, and Pacific Islanders NIH Special Emphasis. Women

Project Summary type here Plan for future funding type here

Duplication of Funding If the Duke and/or UNC CFAR PI is awarded funding under this opportunity and a similar proposal is funded by NIH during the same funding year, the PI receiving the NIH funding must meet with their institutional CFAR leadership to either 1- make sure the research proposal from the CFAR does not overlap with the NIH proposal or 2- return funds to the CFAR or refuse funds from NIH CFAR Mentoring Plan As a condition of award, new and early stage investigators and established researchers new to HIV/AIDS are required to have a mentoring agreement and plan that includes a CFAR member as a constituent. The CFAR member must be a Core Leader/Director or an experienced researcher with a faculty rank of at least Associate Professor. Career development resources available Grant writing at Duke: Gopen Writing Seminars Registration is on a first-come, first-served basis. Faculty are given priority. There are limited seats available for fellows, postdocs, students, and staff. Duke Path to Independence Program/K Club o The Path to Independence is designed to help Assistant Professors secure NIH R01 or DOD funding. o The K Club is a program designed to help junior faculty prepare career development (K) grant applications On-line grant writing resources can be found at https://ors.duke.edu/orsmanual/proposal-writingguides and http://deainfo.nci.nih.gov/extra/extdocs/gntapp.pdf. UNC Awardees are members of the annual UNC CFAR Developmental Cohort, which provides resources and support in monthly meetings, special events and opportunities, and email communications. Signatures (Duke University co-pi) (UNC CFAR co-pi) (Duke Departmental Manager)