EPSRC Strategic Vision and Delivery Plan 21 st March Dr Mark Tarplee

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EPSRC Strategic Vision and Delivery Plan 21 st March 2017 Dr Mark Tarplee

EPSRC in a Changing Environment Department of Business, Energy and Industrial Strategy UKRI IUK 547m EPSRC 858m MRC 616m STFC 529m BBSRC 422m NERC 325m ESRC 178m AHRC 98m QR 1686m

Opportunities Presented by UKRI in brief and not exhaustive! One unified voice for UK research and innovation Simpler innovation ecosystem: national research and innovation strategy stronger links between disciplines and with business, policy makers and the public Reduce administrative costs through sharing of common functions (e.g. HR)

EPSRC Strategic Plan One vision Our vision is for the UK to be the best place in the world to research, discover and innovate Two goals.. RESEARCH and DISCOVER RESEARCH and INNOVATE Three strategies.. Balancing capability Building leadership Accelerating impact

EPSRC Delivery Plan 2016-2021 Strong economies are science economies They invest in research, discovery and innovation. Strong economies are built on the growth and productivity driven by the engineering and physical sciences EPSRC is the most effective means of delivering a world leading, innovative research base that can build a strong UK economy EPSRC will invest in research, discovery and innovation that builds a productive nation a connected nation a resilient nation a healthy nation

Key messages from Council for the 16-21 Delivery Plan Broadly maintain the overall balances between research and skills; Maintain the Impact Acceleration Accounts. Sustain the things that only EPSRC does; Remain open for further fiscal events (e.g. Alan Turing Institute, CDTs); Look to drive further leverage wherever we can; Not just about university match funding- can be working with other government departments, business and charities. Think about how we integrate Official Development Assistance into our plans.

EPSRC s Delivery Plan Framework

RESEARCH CAPABILITIES HEALTHY NATION Improved quality of life through better mental and physical health H1: Transform community health and care H2: Improve prevention and public health H3: Optimise diagnosis and treatment H4: Develop future therapeutic technologies H5: Advance nonmedicinal interventions Advanced materials Disruptive technologies for sensing and analysis Future manufacturing technologies Medical device design and innovation Novel computation and mathematical techniques SKILLS & LEADERSHIP Novel imaging technologies Link to outcomes descriptions on EPSRC website Link to Healthy Nation Convenor Interview

EPSRC Health portfolio April 2016

Role and aims of HT at EPSRC Build critical mass around UK research strengths in engineering and physical sciences that underpin healthcare Maximise industrial and clinical involvement and increase translation to products / practices. All the research we fund is at least 50% in EPSRC remit We fund research across all the low TRL levels (1-4) where there is the potential to contribute to health and there are the collaborations in place to support this

Healthcare Technologies Strategy https://www.epsrc.ac.uk/files/research/htstrategysummary/ 11

Impact and Translation Toolkit Healthcare Technologies Grand Challenge Strategy launched 2015 Accelerating Impact is a key strategy for EPSRC in particular in Healthcare related grants Embed thinking about translation and impact FROM THE OUTSET Researchers do not have to do translation Its about preparing research for those that may take it up in the future What is the toolkit? A spotlight on: resources available to researchers behaviours we want to encourage Healthcare Technologies Strategy Toolkit Link

Core EPS capabilities on healthcare technologies funded grants Other 3% Novel Imaging Technologies 20% Advanced Materials 23% Novel Computational and Mathematical Sciences 9% Medical Device Design and Innovation 24% Disruptive Technologies for Sensing and Analysis 17% Future Manufacturing Technologies 4%

Basic Discovery and Idea Research Invention and Prototype Preclinical Research Early Clinical Trials Late Clinical Trials Regulatory Decision Product Launch Post product Monitoring EPSRC in the healthcare landscape MRC (including UK Regenerative Medicine Platform, Biomedical Catalyst, AMR) EPSRC, BBSRC Innovate UK, including Health KTN, Biomedical Catalyst, Cell and Gene Therapy, Precision Medicine, Medicines Discovery Catapult National Centre for the Replacement Refinement and Reduction of Animals In Research (NC3Rs) Wellcome Trust, Cancer Research UK DoH, including NIHR HTCs, NHS England and AHSNs

Community-led routes for funding Increasing HT investment in investigator led programmes- open call Standard proposals, First Grants, NetworksPlus, Discipline hopping Multidisciplinary panel membership to assess common features of high quality Healthcare Technologies research. Increase your chances of success by: Having the right collaborations in place Demonstrate alignment to HT strategy/healthy Nation in National Importance Reflect research area strategies in National Importance Bespoke specific activities in Pathway to Impact Resource appropriately Use the impact and translation toolkit.

Other funding opportunities- EPSRC HT Healthcare Technologies Challenge Awards round 3 launch late 2017/early 2018. Programme Grants Established career fellowships Discipline hopping Targeted therapeutic delivery EoI to attend scoping workshop in May 17.

Other funding opportunitiesworking with other funders CRUK/EPSRC Multidisciplinary Awards Further two rounds of this initiative per year (open) Healthcare Impact Partnerships 4 launch spring 2017 UK Regenerative Medicine Platform with BBSRC, MRC UK prevention Research Partnership (tbc) Mental Health (with ESRC- tbc)

NHS Eligibility for EPSRC funding From November 2016 RCUK have harmonised IRO eligibility including for NHS investigators An individual that holds a permanent post or fixed term contract (which is longer than the proposed project) at an NHS body with research capability (the Board, NHS Clinical Commissioning Group, NHS Special Health Authority, NHS Trust, NHS Foundation Trust, NHS Local Health Board) is eligible to be an investigator on an RCUK grant. For EPSRC proposals: The proposal must fall primarily within EPSRC s remit if you re unsure please submit a remit query (https://www.epsrc.ac.uk/funding/howtoapply/basics/remit/remitqueries/) Post needs to be at lectureship level or equivalent. Organisations still needs to be registered for RCUK funding on JeS this can take up to 6 weeks! EPSRC will only pay NHS Research Costs. NHS Support and/or Treatment costs will not be supported by EPSRC

Global Challenges Research Fund

EPSRC GCRF activities Institutional Sponsorship Awards (ISAs) 10M 35 universities ~280 projects Tackling global development challenges through engineering and digital technology research 15M In peer review Diagnostics, prosthetics and orthotics to tackle health challenges in developing countries 7.5M Live March 17 Closes May 17 Image: Jon Cooper, U of Glasgow Image: i-sense, UCL Image: Matthew Howard, KCL

Building your networks through EPSRC Networks Plus Established a number of challenge driven research communities focused around addressing one or more of the Grand Challenges To help forge new collaborations with academia, industry and clinicians Funding to develop interdisciplinary collaborations through workshops, visits and part-time coordinators Plus funding for preliminary or feasibility style research to kick start new collaborations within the network, pump primes research proposals to EPSRC or other funders

HT Network Plus Therapy Ultrasound Network for Drug Delivery and Ablation Research (ThUNDDAR), Institute of Cancer Research, Prof GRt ter Haar: Seeks to stimulate translational research that will enable the potential of therapeutic ultrasound to be fully realised. http://www.thunddar.org/ Closed Loop control systems for optimisation of treatment, University of Nottingham, Prof SP Morgan: Seeks to provide a treatment that is optimised and personalised to the individual patient via the closed-loop control approach, which involves continuously monitoring key clinical parameters and, informed by mathematical models, adapting treatment. Fast ASsessment and Treatment in Healthcare (FAST Healthcare), University of Cambridge, Prof AJ Flewitt: Aims to initiate systems-based engineered methodologies for providing joined-up treatment in the public health sector. http://www.fast-healthcare.org.uk/ EPSRC UK Image Guided Therapies Network+, UCL, Prof S Ourselin: Combines simulation and modelling, imaging and sensing, computing, robotics as well as visualisation to improve the localisation and targeting of pathological tissue with surgical instruments and focused energy delivery. http://www.image-guided-therapies.ac.uk/ Grand Challenge Network+ in Proton Therapy, University of Manchester, Prof KJ Kirkby: Aims to create a national infrastructure to meet a national research and training need that will allow the UK community to work together in the multi-disciplinary field of proton research.

A reminder. Remit query: Use the form here and we will work across RCs to find the best home for your research. Cross Council Funding agreement: applies in responsive mode only In principle applies to all grants but contribution of non-lead Council is capped (unless other arrangements have been made before the proposal is submitted)

EPSRC Healthcare Technologies Theme Annette Bramley Theme lead (Overall strategy, budget) Lewis Preece Senior Portfolio Manager (Impact, WT) Iain Larmour Senior Portfolio Manager (Regenerative therapies, Balancing Capability, CRUK) Anne Farrow Senior Portfolio Manager (Leaders, Technologies for a healthy lifecourse) Sarah Hobbs Portfolio Manager (Digital technologies, ICT) Mark Tarplee Portfolio Manager (Medical Imaging, Maths/Engineering) Stephanie Newland Portfolio Manager (AMR, Novel therapeutics, drug delivery, Phys Sci) Martin Champion Portfolio Manager (Assistive Technologies, Medical devices) Sarah Ashwood Portfolio Manager (Clinical tech & Biomaterials and tissue Engineering) vacancy, Linda Norris Support Team Firstname.lastname@epsrc.ac.uk; healthcare@epsrc.ac.uk; https://www.epsrc.ac.uk/funding/howtoapply/basics/remit/remitqueries/

Questions? Thanks for listening Further questions and enquiries can be sent to: healthcare@epsrc.ac.uk Or contact a member of the Healthcare team see here