3rd Annual Sawyer Pancreato-Biliary and Gastrointestinal Cancer Symposium at TSGE:

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MD Anderson 3rd Annual Sawyer Pancreato-Biliary and Gastrointestinal Cancer Symposium at TSGE: September 21, 2018 Case-Based Learning and Discussions Hilton Austin 500 East 4th Street Austin, Texas Program Chairs

Goal The goal of this Symposium is to understand how cholangiocarcinoma and other biliary pancreatic cancers can be best managed by clinicians in this area. During this international symposium, the experts from various regions of the world will share the findings of their research, clinical experience, and recommendations regarding these cancers. We expect this symposium will change the practice of the attendees who will acquire the state-of-the-art clinical information about the diseases, thus improving the overall survival of patients with the diseases. Educational Objectives Educational Methods After attending the conference, Lectures Panel Discussions Case participants should be able to Studies - Question and Answer Sessions Apply the strategy in establishing Target Audience diagnosis promptly (Knowledge, Competence, Performance); This symposium should be of value to gastroenterologists, medical oncologists, Perform appropriate endoscopic surgeons, interventional radiologists, and procedures (Knowledge, Competence, internists. Performance); Incorporate the updated chemotherapy Evaluation regimen and radiation treatment in A course evaluation form will provide patient care (Knowledge, Competence, participants with the opportunity to Performance); comment on the value of the program Provide appropriate referral to content to their practice decisions, the specialty in a timely manner performance improvement activities, or (Knowledge, Competence); possible impact on patient health status. Participants will also have the opportunity Implement multidisciplinary approach in to comment on any perceived commercial care of patients with cancers to improve bias in the presentations as well as to patient care (Knowledge, Competence, identify future educational topics. Performance, Patient Outcomes). Accreditation/ Credit Designation PHYSICIANS The University of Texas MD Anderson Cancer Center is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Texas MD Anderson Cancer Center designates this live activity for a maximum of 5.00 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. CME Certificates and Attendance Verification Certificates Certificates awarding AMA PRA Category 1 Credit or certificates documenting attendance will be distributed to participants as they depart the symposium. To obtain a CME certificate, physicians must submit a completed evaluation questionnaire and a CME Verification Form. Upon request, a record of attendance (certificate) will be provided on-site to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations. MD Anderson Program Planning Committee PROGRAM CO-DIRECTORS COMMITTEE MEMBERS Brian R. Weston, MD Associate Carol Cox Program Coordinator Constance C. Tierney, CMP Manager CME/Conference Management

Program Friday, September 21, 2018 11:30 a.m. Registration/Exhibits/Lunch (provided) Noon Welcome and Opening Remarks John R. Stroehlein, MD CHOLANGIOCARCINOMA Moderators: ; Gottumukkala S. Raju, MD 12:10 p.m. Sharing of MD Anderson Experience and Algorithm in Managing Malignant Hilar Strictures 12:25 The Impact of Hepatic Vascular Anomalies on Operability in Hilar Cholangiocarcinoma: Surgeon s Perspective Thomas A. Aloia, MD 12:40 Hilar Cholangiocarcinoma: A Management Dilemma of Medical Oncology Milind Javle, MD 12:55 Advances in Managing Biliary Cancers in Japan: Surgeon s Perspective Yoshikuni Kawaguchi, MD, PhD 1:10 Endoscopic Management of Difficult Hilar Strictures Present and Future In South Korea Dong Ki Lee, MD, PhD 1:25 Questions and Answers With Panel 1:40 Break/Exhibits CONUNDRUMS IN ENDOSCOPY Moderators: Binh V. Pham, MD; Jay N. Yepuri, MD 2:00 Solving Biliary and Pancreatic Problems After Surgery David L. Carr-Locke, MD 2:15 Difficulties in Managing Pancreatobiliary Malignancy in the Community Harish K. Gagneja, MD 2:30 Determining Your Options for Indeterminate Stricture Prashant Kedia, MD 2:45 Pancreatic Drips, Disruptions, and Disconnections Paul R. Tarnasky, MD 3:00 Break/Exhibits PANCREATIC NEOPLASMS Moderators: ; Brian R. Weston, MD 3:15 Updates in Imaging in the Field of Pancreatobiliary Diseases Eric P. Tamm, MD 3:30 Endoscopic Management of Pancreatic Cancer in Japan Hiroyuki Isayama, MD 3:45 Useful Tips for Successful Endoscopic Management of Biliary Obstruction in Pancreatic Cancer Brian R. Weston, MD 4:00 Role of EUS in Diagnosis and Management of Pancreatic Neuroendocrine Tumors GASTROINTESTINAL NEOPLASMS Moderators: Patrick M. Lynch, MD; Gottumukkala S. Raju, MD 4:15 Difficult Cases of Stomach Polyps Related to Inherited Susceptibility Patrick M. Lynch, MD 4:30 Endoscopic Submucosal Dissection of Esophageal, Gastric, and Colonic Neoplasms: Eastern Approach Young Hoon Youn, MD, PhD 4:45 How to Resect a Large Flat Lesion: MD Anderson Protocol and Results Gottumukkala S. Raju, MD 5:10 Questions and Answers With Panel 5:30 Closing Remarks/Adjourn

MD Anderson Faculty Guest Faculty Thomas A. Aloia, MD Gottumukkala S. Raju, MD David L. Carr-Locke, MD Paul R. Tarnasky, MD Head of the Institute for Cancer Care Clinical Director Medical Director Associate John Stroehlein Distinguished The Center for Advanced Digestive Care Methodist Digestive Institute Surgical Oncology Weill Cornell Medicine Program Director Walter B. Wriston Distinguished for Pancreatic Cancer Research Director of Endoscopic Research and Development John R. Stroehlein, MD and Chair Eric P. Tamm, MD Diagnostic Radiology New York Presbyterian Hospital New York, New York Harish K. Gagneja, MD Senior Partner, Austin Gastroenterology, PA Immediate Past President, TSGE ACG Governor for South Texas Austin, Texas Gastroenterology Fellowship Digestive Health Associates of Texas Dallas, Texas Jay N. Yepuri, MD Advanced Endoscopy and Managing Partner Digestive Health Associates of Texas, PA President, Texas Society for Gastroenterology Milind Javle, MD GI Medical Oncology Brian R. Weston, MD Associate Hiroyuki Isayama, MD Department of Gastroenterology and Endoscopy Bedford, Texas Young Hoon Youn, MD, PhD and Medical Director of Endoscopy Patrick M. Lynch, MD Graduate School of Medicine Juntendo University Tokyo, Japan Yoshikuni Kawaguchi, MD, PhD Assistant Department of Surgery The University of Tokyo Associate Department of Gastroenterology Gangnam Severance Hospital Yonsei University College of Medicine Seoul, South Korea Tokyo, Japan Prashant Kedia, MD Medical Director of Interventional Endoscopy Methodist Dallas Medical Center Dallas, Texas has implemented a process whereby everyone who is in a position to control the content of an educational activity must disclose all relevant financial relationships with any commercial interest that could potentially affect the information presented. MD Anderson also requires that all faculty disclose any unlabeled use or investigational use (not yet approved for any purpose) of pharmaceutical and medical device products. Specific disclosure will be made to the participants prior to the educational activity. Agendas are subject to change because we are always striving to improve the quality of your educational experience. MD Anderson may substitute faculty with comparable expertise on rare occasions necessitated by illness, schedule conflicts, and so forth. Dong Ki Lee, MD, PhD Director, Department of Internal Medicine Gangnam Severance Hospital Yonsei University College of Medicine Seoul, South Korea Binh V. Pham, MD Interventional Gastroenterology Austin Gastroenterology, PA Austin, Texas Photographing, audio taping and videotaping are prohibited.

Registration Information On-site registration opens at 11:30 a.m. on Friday, September 21, 2018. The symposium will begin at Noon and adjourn at 5:30 p.m. on Friday, September 21, 2018. Advanced registration is encouraged as space and materials are limited. Please see the registration form for applicable fees. The full conference registration fee includes the tuition, program syllabus, lunch, and breaks. The deadline for advanced registration is Friday, September 7, 2018. There are three ways to register: 1. On-line at www.mdanderson.org/conferences 2. Fax to: 713-794-1724 3. Mail to: CME/Conference Management Unit 1781 P.O. Box 301407 Houston, TX 77230-1407 When registering online a confirmation letter will be automatically e-mailed to the e-mail address you list on the registration form. If you register by fax or mail, a receipt/ confirmation letter will be sent to you within ten working days of receipt of your registration. Special Assistance Contact CME/Conference Management at 713-792-2223 or toll free at 866-849-5866 if you have any special dietary or ADA accommodation needs. Accommodations A block of rooms is available for symposium attendees at the Hilton Austin, 500 East 4th Street, Austin, TX 78701. The special meeting rate is $232.00 single or double occupancy. Please add 17% Texas State and local taxes. Reservations can be made through the TSGE room block which will open in early July. Check website at www.mdanderson.org for updates. Ground Transportation Transportation from Austin-Bergstrom International Airport to and from the Hilton Austin is available by taxi at approximately $30/each way; and also by Super Shuttle. For Super Shuttle please make reservations at www.supershuttle.com and use code HILTN for a 5% discount. The cost is approximately $16/each way. Please let us know what specific topics, issues or questions you wish to see addressed or emphasized in this activity. Fax or e-mail CME/Conference Management. All responses will be forwarded to the Program Chairs for consideration. CME/Conference Management reserves the right to cancel activities prior to the scheduled date, if low enrollment or other circumstances make it necessary. Each registrant will be notified by mail, e-mail, or at the phone or fax numbers given on the registration form. In case of activity cancellation, the liability of CME/Conference Management is limited to the registration fee. CME/Conference Management will refund the full registration fee. CME/Conference Management reserves the right to limit the number of participants in a program and is not responsible for any expenses incurred by an individual whose registration is not confirmed and for whom space is not available. Please let us know what specific topics, issues or questions you wish to see addressed or emphasized in this activity. Fax or e-mail CME/Conference Management. All responses will be forwarded to the Program Chairs for consideration.

CONFERENCE REGISTRATION- 176700/30/120867/41 PS 110870 3rd Annual Sawyer Pancreato-Biliary and Gastrointestinal Cancer Symposium at TSGE: Case-Based Learning and Discussions September 21, 2018 Last Name First MI Highest Degree Department (include unit no.) Specialty Institution MD Anderson Employee ID No. (required for all MDACC employees): Physician Street Yes No City State/Foreign Country/Zip or Mail Code Daytime Phone (with area code) Cell Phone (with area code) Fax (with area code) E-mail Address (please print) Emergency Contact Phone (with area code) Credit Card Holder Name (First/Last) Charge the following: VISA MC AMEX Credit Card Number Expiration Date Security Code/CVV/CSV Credit Card Holder Billing Address & ZIP Code MD Anderson Interdepartmental Transfer (IDT) No.: *Fund Group 90 will not be accepted Business Unit Department Fund Group* Fund Fund Type Authorized Signature REQUIRED for CREDIT CARD or IDT IDT Approver Name (First/Last) please print THIS IS NOT A SELF-MAILER - Address to: 3rd Annual Sawyer Pancreato-Biliary and Gastrointestinal Cancer Symposium at TSGE: Case-Based Learning and Discussions September 21, 2018 CME/Conference Management Unit 1781 PO Box 301407, Houston, TX 77230-1407 or fax to 713-794-1724 Make check or money order payable to: Registration Fees 1TSGE Members....$49.00 1Physicians...$99.00 1Students/Fellows/Residents /HC Professionals...$25.00

CME/Conference Management- Unit 1781 176700/30/120867/41 PO Box 301407 Houston, TX 77230-1407 Non-Profit Org. U.S. Postage P A I D Houston, TX Permit No. 7052