Enhanced recovery after surgery: the role of the PACU & Pre-op

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Enhanced recovery after surgery: the role of the PACU & Pre-op Magnus K. Teig BSc (Hons.) MBChB MRCP FRCA EDIC FFICM Assistant Professor Anesthesia & Neurosurgery Director UH PACU University of Michigan

Learning Objectives 1. Review the evolution and origins of Enhanced Recover after surgery (ERAS) programs and the role of the PACU within them 2. Discuss the future implications of ERAS on the PACU & pre-op areas and on peri-operative practice

Disclosures None

Acknowledgements Dr. Samantha Hendren Associate Professor of Surgery, Colon & Rectal Surgery Michigan Medicine Dr. Scott Ellis Regenbogen Associate Professor of Surgery, Colon & Rectal Surgery Michigan Medicine Dr. Andrew Gray Urquhart Associate Professor, Orthopedic Surgery Michigan Medicine Dr. Paul Hilliard Assistant Professor, Anesthesia & Pain Michigan Medicine

Enhanced Recovery after surgery (ERAS) What is ERAS anyway? Multidisciplinary bundles of care Aim to hasten recovery and shorten stay

What is ERAS?

Where did ERAS begin? Prof. Henrik Khelet MD PhD Colorectal surgeon Hvidovre Hospital (post 2004 Rigshospitalet København) Pre-emptive analgesia - epidurals and nitrogen balance Evolved to fast track surgery mid 1990 s ERAS born 2001

From: Henrik Kehlet, M.D., Ph.D., Recipient of the 2014 Excellence in Research Award Anesthes. 2014;121(4):690-691. doi:10.1097/aln.0000000000000396 Figure Legend: Henrik Kehlet, M.D., Ph.D., recipient of the American Society of Anesthesiologists 2014 Excellence in Research Award. Date of download: 12/1/2017 Copyright 2017 American Society of Anesthesiologists. All rights reserved.

http://enhancedrecoverybc.ca/learning-sessions- 2/outcomes-congress-jan-12-2016/

Kenneth Fearon MBBCh (Hons.), MD, FRCPS (Glasgow), FRCS (Edinburgh), FRCS (England) Royal Infirmary of Edinburgh Founding member of ERAS group Chairman ERAS Society 1960-2016

ERAS Societies

ERAS USA founded 10/16/2016 ERAS USA, the ERAS Society USA Chapter, held its founding meeting October 16, 2016, at the Marriott Marquis Hotel in Washington, DC. Starting in the preoperative setting, we advise patients to improve their overall health with nutrition, exercise, smoking cessation, and alcohol cessation. Patient education about the surgical process and recovery further brings the patient to the center of their care. http://erasusa.org/

ERAS USA Meetings

Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery Acta Anaesthesiologica Scandinavica Volume 59, Issue 10, pages 1212-1231, 8 SEP 2015 DOI: 10.1111/aas.12601 http://onlinelibrary.wiley.com/doi/10.1111/aas.12601/full#aas12601-fig-0001

https://www.rcoa.ac.uk/erp

Why bother with ERAS? Colorectal example: Length of stay 2.5 days less Complications - 50% less in colonic surgery Cost - $2,245 per patient 1. U.O. Gustafsson, M.J. Scott,W. Schwenk, N. Demartines, D. Roulin, N. Francis, et al., Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations, World J. Surg. 37 (2) (2012) 259 284. 2. M. Greco, G. Capretti, L. Beretta,M. Gemma, N. Pecorelli,M. Braga, Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials, World J. Surg. 38 (6) (2014) 1531 1541. 3 O. Ljungqvist, E. Jonathan, Rhoads lecture 2011: insulin resistance and enhanced recovery after surgery, J. Parenter. Enter. Nutr. 36 (4) (2012 Jul) 389 398.

ERAS general recommendations 16 different guidelines Do your job well! Surgical themes Anesthesia themes Perioperative nursing and therapy themes

Surgical themes Practice asepsis, clean patient in a standard way Use appropriate prophylactic antibiotics Minimally invasive surgery Minimally disruptive preparation Pre-habilitation of patients Minimize fasting and mobilize asap

Anesthesia themes Accommodate fasting times Multimodal analgesia Use Neuro-axial / Regional / Local anesthetic Reduce or avoid opiates Reduce fluids if possible Multimodal anti-ponv

Perioperative nursing and therapy themes Feed asap Mobilize asap Therapies asap Reduce fasting times Provide aids to get home Patient and family expectations Patient education

C'est un effort d'équipe

Barriers to ERAS in the PACU Early nutrition in PACU culture change to feed Mobility in the PACU space and staff to assist Reporting back to in room providers perioperative providers versus intra-operative providers Lack of a common protocol for ERAS

General surgeon Day 0 problems Reducing fluid boluses for low UO Reducing narcotics often given PACU or on ward Starting nutrition

Food in the PACU I never feed my patients! I do not feed them if they are out patients. They might puke! Personal snapshot survey Michigan Medicine PACU, 12/1/2017

Post op nutrition options

Michigan TKA / THA experience 2012 3.5 days stay Dealer s choice anesthesia now standardized Clear liquids, PCA, pain service referral

Michigan TKA / THA experience Protocolized experience 4.5 hour pre-op course 2017 1 day stay (median <24 hours) Now physical therapy starts in PACU, neuraxial regional anesthesia, clear liquids

Perceived barriers to Orthopedic protocol Chicken broth 6 hours fasting (!?) Feeding in the PACU food versus fear of PONV Therapy support and space to mobilize in the PACU PACU holds may delay therapies

Orthopedic analgesic protocol

Orthopedic experience results RAMP Protocol Traditional Protocol Mean P Value CI, 95% Length of Stay (days) 2.1 2.89 <0.01-1.1 to -0.4 IV morphine equivalents (mg) Intraoperative 5.29 10.14 <0.01-7.3 to -2.4 PACU 2.99 4.54 0.1-3.4 to 0.3 General Floor (Oral) 31.83 48.93 <0.01-29.8 to -4.36 General Floor (IV) 1.59 23.89 <0.01-30.4 to -14.9 Combined opioid consumption 41.35 87.5 <0.01-65.4 to -26.9 LESS READMISSIONS NOW 9% (from 36%)

Michigan ERAS - Donor Nephrectomy With thanks to Dr. Seth Waits transplant surgeon Data from Dr. Paul Hilliard

Pre Op Smoking Cessation Carbohydrate Drink Acetaminophen (1 gram PO in holding area)

Intra Op Post Induction TAP block Standard fluid administration Ketorolac IV at end of case

Post Op Scheduled non-narcotic pain medications Early Ambulation Early Regular Diet Improved Discharge Planning

Less time in PACU; less time overall 300 250 Time in PACU 200 150 Standard therapy n = 40 ERP with TAP block n = 31 100 Time to incision 50 0 Average time added to induction with TAP block (min) Length of stay in PACU (min)

Less opioid use 45 40 35 30 25 20 ERP with TAP n = 31 Standard therapy n = 40 15 10 5 0 PCA use (mg morphine) Total opioid use (including PO) during hospitalization

Faster discharge from hospital 60 50 40 30 ERP with TAP Standard Therapy 20 10 0 Hospital Length of Stay (in hrs)

Similar pain scores in the PACU 5 Post-operative Pain Scores 4.5 4 3.5 Pain Score (0-10) 3 2.5 2 1.5 1 0.5 0 ERP Standard

Less post operative pain on ward 4.4 4.2 4 3.8 Average VAS with ERP Average VAS with standard therapy 3.6 3.4 3.2 POD 0 POD 1

ERAS and Pre-op Concept of batching patient arrivals and procedures e.g. >1 patient may have an epidural placed; most effective has their operation 1 st Implications on pre-op holding load and staff Letting patients drink in pre-op

Why change to adopt ERAS?

Why change to adopt ERAS? https://www.cms.gov/outreach-and-education/medicare- Learning-Network- MLN/MLNProducts/downloads/Hospital_VBPurchasing_Fac t_sheet_icn907664.pdf

Why change to adopt ERAS? https://www.cms.gov/outreach-and-education/medicare- Learning-Network- MLN/MLNProducts/downloads/Hospital_VBPurchasing_Fac t_sheet_icn907664.pdf

Value Based Purchasing timetable https://www.cms.gov/outreach-and-education/medicare- Learning-Network- MLN/MLNProducts/downloads/Hospital_VBPurchasing_Fac t_sheet_icn907664.pdf

Why change to adopt ERAS? Pay for performance model Quality valued over quantity https://www.ama-assn.org/practice-management/medicare-alternative-payment-models

C'est un effort d'équipe = Team effort

How to move ERAS forwards Local and regional collaboration UK example Meetings and education national and international Audit to collect data of successful implementation Work on barriers from staff fasting, analgesia, modes of anesthesia Work on patient education & expectation key to success

Eras Society Many different sets of guidelines Commercial products exist to help implement ERAS 8 month program Colorectal Bladder surgery Breast surgery Gastrectomy Bariatic Upper GI Gynaecological Head and neck Pancreaticoduodenectomy Rectal and pelvic http://erassociety.org.loopiadns.com/guidelines/list-of-guidelines/

https://www.encare.net/healthcareprofessionals/products-and-services/erasimplementation-program-eip

ERAS Implementation process (UK) Hospital steering groups Audit current practice Milestones agreed Education plan Implement Re-audit http://www.enhancedrecoveryblog.com/index.php/spread-adoption-enhanced-recovery/

1715 hospital days saved http://www.enhancedrecoveryblog.com/index.php/spread-adoption-enhanced-recovery/

ERAS is a continuum The OR and perioperative experience is only 1 small part of it It starts with the H&P at clinic Behavior modification, training and nutrition Hospital stay including anesthetic Rehabilitation & nutrition Post operative mobility & support

Questions?