ISOLS/MSTS 2015 Abstract Submission Guidelines

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ISOLS/MSTS 2015 Abstract Submission Guidelines The ISOLS and MSTS program committees welcome abstracts relative to all aspects of musculoskeletal oncology and limb salvage and are especially interested in the "Category" topics listed on the abstract submission form. You or one of your co-authors must be a member of MSTS or ISOLS to submit an abstract for the meeting. All abstract submitters must have an MSTS Customer ID# to log into the system. If you are not a member of MSTS or ISOLS, however, if one of your co-authors is a member of either organization, please email the MSTS Staff (info@msts.org) with your co-author s full name as well as your full name, mailing address, phone and fax numbers, and an email address, and the staff will email you a MSTS Customer ID#. NEW IN 2015 CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (CORR ) We strongly encourage everyone submitting an abstract to also submit their manuscript as soon as possible to Clinical Orthopaedics and Related Research (CORR ), the official journal of MSTS and ISOLS. CORR will consider for publication in the MSTS/ISOLS proceedings of the 2015 joint meeting any podium or poster presentation. Please note, though, that presentation at the meeting does not guarantee publication; CORR publishes only those papers that pass editorial screening and peer review. (In the unusual circumstance that the abstract is not accepted for the meeting but the manuscript is accepted by CORR, it would be published in CORR as a regular submission, or simply wait to hear if your abstract has been accepted before submitting the manuscript). The deadline for manuscript submission to be considered for the proceedings is November 10, one month after the meeting. However, you may submit your manuscript now, rather than waiting for an invitation after the meeting as was done in the past. Those applying for one of the awards (see below) are required to submit a manuscript to CORR by August 1 as part of the selection process. Although we strongly encourage all authors to submit their manuscript to CORR, this is required only of those who wish to be considered for an MSTS/ISOLs annual meeting award. We cannot overemphasize the importance of submitting papers to CORR so that there will be a written record of the meeting and so that others can benefit from your hard work, expertise, and findings. Manuscripts may be submitted at http://www.editorialmanager.com/corr. Indicate in the drop down menu if the submission is for an MSTS/ISOLS Award or if you do not want to be considered for an award, choose MSTS/ISOLS proceedings. Advantages of publishing in CORR :

CORR publishes more musculoskeletal oncology papers than any other journal: Readers look to CORR first for relevant musculoskeletal oncology research Average time from submission to electronic publication is fast just about 4 months A robust MSTS/ISOLS proceedings issue in CORR extends our societies brands, and increases the visibility of the important work our societies do No longer a five-author rule ICMJE s authorship guidelines apply Easy-to-use article template to help you write an informative paper CORR promotes important papers with Editor s Spotlight features, Take-5 Interviews, and CORR Insights commentaries AWARDS 1. Young Investigator Award Currently in training or within 5 years of completion of orthopaedic oncology fellowship. (1 st Place $1,000; 2 nd Place, $750; 3 rd Place, $500) a. In the cover letter to the manuscript, describe your role in project, ie who conceived of the idea, gathered the data, analyzed the data, wrote the abstract and manuscript). What stage of your training are you at or when did you complete your fellowship? 2. Best Podium Presentation (1 st Place, $1,000; 2 nd Place, $750; 3 rd Place, $500) 3. Best Poster (1 st Place, $500; 2 nd Place, $250; 3 rd Place, $250) 4. Best Collaborative Study ($1,000) Note: To be eligible for the Young Investigator, Best Podium, and Best Collaborative Study awards, you must submit a manuscript to CORR by August 1, 2015 through the CORR website http://www.editorialmanager.com/corr. The program committee will review manuscripts as part of the selection process. All Young Investigator and Best Podium award winners are required to publish their manuscript in CORR IF IT PASSES PEER REVIEW. WINNING AN AWARD DOES NOT GUARANTEE ACCEPTANCE FOR PUBLICATION. All awards submissions (winners and non-winners) will be converted to CORR manuscript submissions and considered for publication, so these papers cannot be submitted to any other journal until they have been evaluated at CORR. Awards will be announced at the meeting, however, the monetary portion will not be made until the peer review process and manuscript revision process are completed. When you submit your manuscript to CORR indicate in the drop down menu that it is under consideration for an MSTS/ISOLS award. MSTS/ISOLS Awards Winners passing CORR s review will be published in CORR under a banner 2015 MSTS/ISOLS Awards Paper and promoted by the Journal. IMPORTANT NOTE: You do not need to submit a paper for the awards process to have your paper considered for publication in the proceedings. We encourage you to submit a paper for publication in the annual CORR MSTS/ISOLS Proceedings issue even if you do not wish to be considered for an award. Simply indicate in the drop down menu on the CORR website that it is under consideration for the MSTS/ISOLS meeting proceedings.

ISOLS Members will be eligible for the ISOLS Best Poster Award. MSTS Members will be eligible for the MSTS Best Poster Award. Members of both organizations will be eligible for both awards. If you win the MSTS best poster, it will be displayed at the 2016 Orthopaedic Research Society (ORS) Meeting, in the best Specialty Society Posters Section and you will be required to leave your poster with MSTS staff so that it can be sent to the ORS, after which it will be returned to you. If you wish to attend the ORS meeting you may do so at your own expense. We require ELECTRONIC SUBMISSION of your abstract. All online submissions must include: 1. Financial Disclosure is required for each author. 2. Submitter: If you are an AAOS member and your disclosure is up-to-date in the AAOS database, you will automatically enter the abstract submission process. If your disclosure is not current, you will be directed to the AAOS website to update your disclosure. If you are not an AAOS member, you will be directed to the MSTS disclosure database to submit your disclosure. After your disclosure is current, you may begin the abstract submission process. 3. You must have the last name and email address for every co-author on the abstract. If your co-authors are not in the AAOS disclosure database or do not have a record in the MSTS database, you will also need to obtain their financial disclosure information to enter it during your abstract submission process. 4. Once you have submitted your co-authors, you will be able to review the co-author submission information to see their disclosure status. If during your search for a co-author the author was not found and you had to enter that author, you will then have to click the Disclose for this Co- Author link to submit their disclosure information on their behalf. 5. Uploading Abstracts: Once you have completed the author/co-author steps, you will then be brought to the abstract upload page. Here, you are required to upload both a blind and full version of your abstract. (Blind = No Authors/Co-Authors or Institutions; Full = All Authors/Co- Authors and Institutions). Please Note: On this page, your abstract number is listed. Please be sure to include this number at the top of both the blind and full versions of your abstract prior to uploading. Once you have uploaded both versions of your abstract, you should see a link to each version listed on the screen along with a Thank You message. You will NOT receive a confirmation email after uploading your abstract. The best way to be sure your abstract was submitted and that it is complete, is to check the Status. You will see a Return to Main Menu link toward the top right-hand side of the abstract upload page. Once on the Main Menu page, you will see that the Status will say: Complete or Pending. If Pending, it will state why it is pending (missing abstract files or disclosure information). 6. Levels of Evidence: To refer to the Levels of Evidence table, please view the last page of these instructions. Please see the following information regarding the content of your abstract: 1. Structure:

a. Background: include what is the rationale for the study; what is known; what is not known b. Questions/Purposes: state 2-4 questions or purposes oriented around specific endpoints; logically follows background c. Patients and Methods: include what is relevant: study design (in vivo, in vitro, prospective, retrospective, randomized, case-control, case series, etc.), controls, diagnostic criteria, inclusion and exclusion criteria, dates, treatment, follow-up, methods, comparisons made, and statistical methods. Please use validated outcome instruments such as MSTS, TESS, ISOLS Classification of Limb-Sparing Reconstructions. d. Results: provide an answer to each question or purpose, provide an estimate of effect size (odds ratio, hazard ratio, or other metrics) and relevant statistical results and p values e. Conclusions: synthesis of literature and findings, limitations, clinical relevance 2. Length: Please submit a Microsoft Word document that does not exceed 750 words. a. Note: if you submit a manuscript to CORR, the abstract length will need to be edited down to 250 words 3. Font: Standard Calibri font, type size 10pt. 4. Format: Abstract should be single spaced with a 1 inch margin both on the top and bottom as well as the left and right sides. Note: Each abstract is assigned a number. Please be sure to include this number at the top of your abstract. 5. Figures and Tables: Limit 2. 6. References: Please omit any reference to authorship and/or institution within the body of the abstract. Please contact the MSTS office with any questions via email at info@msts.org or by phone at USA: 1.847.698.1625 International: 011.847.698.1625 Thank you. ISOLS/MSTS Musculoskeletal Tumor Society Administrative Office 9400 W. Higgins Road, Suite 500 Rosemont, IL 60018 Direct USA: 1.847.698.1625 International: 011.847.698.1625 Fax: 847.268.9574 Email: info@msts.org

Clinical Orthopaedics and Related Research Ò Levels of Evidence for Primary Research Question a [This chart was adapted from material published by the Centre for Evidence-Based Medicine, Oxford, UK. For more information, please see www.cebm.net.] Types of Studies Level Therapeutic Studies Investigating the Results of Treatment Prognostic Studies Investigating the Effect of a Patient Characteristic on the Outcome of Disease Diagnostic Studies Investigating a Diagnostic Test Economic and Decision Analyses Developing an Economic or Decision Model I II III d High quality randomized trial with statistically significant difference or no statistically significant difference but narrow confidence intervals d Systematic review b of Level I RCTs (and study results were homogenous c ) d Lesser quality RCT (eg, < 80% followup, no blinding, or improper randomization) d Prospective d comparative study e or with inconsistent results d Case control study g d Retrospective f comparative study e d Systematic review b of Level III studies d High quality prospective study d (all patients were enrolled at the same point in their disease with P80% of enrolled patients) d Retrospective f study d Untreated controls from an RCT d Lesser quality prospective study (eg, patients enrolled at different points in their disease or <80% followup) d Case control study g d Testing of previously developed diagnostic criteria on consecutive patients (with universally applied reference gold standard) d Development of diagnostic criteria on consecutive patients (with universally applied reference gold standard) d Study of nonconsecutive patients; without consistently applied reference gold standard Level III studies IV Case series h Case series d Case-control study d Poor reference standard d Sensible costs and alternatives; values obtained from many studies; with multiway sensitivity analyses d Sensible costs and alternatives; values obtained from limited studies; with multiway sensitivity analyses d Analyses based on limited alternatives and costs; and poor estimates Level III studies d Analyses with no sensitivity analyses V Expert opinion Expert opinion Expert opinion Expert opinion a A complete assessment of quality of individual studies requires critical appraisal of all aspects of the study design. b A combination of results from two or more prior studies. c Studies provided consistent results. d Study was started before the first patient enrolled. e Patients treated one way (eg, cemented hip arthroplasty) compared with a group of patients treated in another way (eg, uncemented hip arthroplasty) at the same institution. f The study was started after the first patient enrolled. g Patients identified for the study based on their outcome, called cases eg, failed total arthroplasty, are compared with patients who did not have outcome, called controls eg, successful total hip arthroplasty. h Patients treated one way with no comparison group of patients treated in another way.