SLMTA/SLIPTA Symposium November 28-29, 2014 Cape Town, South Africa. A satellite meeting to the ASLM2014 Conference.

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SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference SLMTA Updates Katy Yao, Ph.D. SLMTA Global Program Director US Centers for Disease Control and Prevention 1

SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference Question ❶ As of December 2013, how many countries have implemented SLMTA? A. 25 B. 39 C. 47 D. 53

SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference Question ❷ As of December 2013, how many laboratories have implemented SLMTA? A. 501 B. 617 C. 704 D. 952 3

SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference Question ❸ As of December 2013, how many people have been trained in SLMTA? A. 906 B. 1,234 C. 1,507 D. 1,923 4

Spread of the SLMTA Program 2010-2013 Total # countries 47 Guatemala Belize El Salvador Honduras Nicaragua Costa Rica Panama Colombia Peru Bahamas Jamaica Haiti Dominican Republic - St Kitts - Antigua - Dominica - St Lucia - St Vincent - Grenada Sierra Leone Barbados Trinidad & Tobago Cote Ghana Suriname d Ivoire Nigeria Cameroon Democratic Republic of Congo Angola Zambia Namibia # laboratories enrolled 617 # people trained 1,923 Zimbabwe Botswana Ethiopia South Sudan Uganda Kenya Rwanda Burundi Tanzania Malawi Mozambique Vietnam Cambodia South Africa Swaziland Lesotho Year when SLMTA was initiated: 2010 2011 2012 2013

SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference Question ❹ What is the average of the baseline SLIPTA score (%) for all the SLMTA-enrolled laboratories (n=617)? A. 39% B. 49% C. 59% D. 69% 6

SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference Question ❺ What is the average improvement from baseline to exit audit score for all the laboratories that have completed SLMTA (n=302)? A. 15 percentage points B. 25 percentage points C. 35 percentage points D. 45 percentage points 7

Stars Baseline vs. Exit Audit Results (n=302) Baseline Exit 5 Stars 4 Stars 3 Stars 2 Stars 1 Star 0 Stars Average Score 39% 64% 5 4 3 2 Note: Each square represents one laboratory 1 85% 0 30% Average Implementation Time = 16 months 8

Percentage point difference between exit and surveillance audit scores Post-SLMTA Surveillance Audit (n=92) 100 90 80 70 60 50 40 30 20 10 0-10 -20-30 -40 Median of 11 months (5-28 months) post exit 38% of these laboratories failed to improve from exit 62% of these laboratories further increased their scores from exit Laboratories

SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference Question ❻ To date, how many SLMTA-enrolled laboratories have achieved international accreditation? A. 5 B. 6 C. 7 D. 8 10

From SLMTA to International Accreditation Laboratory Name Type of Laboratory Time from SLMTA enrollment to accreditation Baseline Score 1. HIV National Reference Laboratory, Kenya National 35 months 45% 2. KEMRI/CDC TB Laboratory, Kenya National 17 months 75% 3. HIV National Reference Laboratory, Bahamas National 28 months 38% 4. Hai Duong Prevention Medicine Center, Vietnam Regional/ Provincial 19 months 29% 5. Cimas Harare Medical Laboratory, Zimbabwe 6. Bungoma District Hospital Laboratory, Kenya Private 54 months 34% District 43 months 38% 7. Nyangabgwe Referral Hospital Laboratory, Botswana Regional/ Provincial 35 months 75% Median 35 months 38%

Estimated proportion of 43.5 million laboratory tests performed by star level before and after SLMTA implementation (n=302) 3 Stars 2% 16% 1 Star 11% 2 Stars 2% 4 Stars 0% 0 Stars 84% Score 45-54% 23% Score 35-44% 22% Score 25-34% 12% Score 0-24% 27% Before SLMTA 16% of tests done in laboratories with at least 1 star 5 Stars 1% 23 million tests were done by labs 0 stars before 1 or stars 2 Stars 68% 20% 1 Star 19% 0 Stars 32% Score 45-54% 20% After SLMTA 68% of tests done in laboratories with at least 1 star Score 35-44% 10% 3 Stars 21% 4 Stars 7% 5 Stars 1% Score 25-34% 2%

Cumulative Number of SLMTA Trainers, Master Trainers, and TOTs (2009-2013) 13

Geographic Distribution of the 38 master trainers 1 2 3 4 5 97% of the TOT graduates and 87% of the master trainers are based in developing countries across Africa, Southeast Asia, and Latin America 14

AJLM s Special Supplement on SLMTA

AJLM s Special Supplement on SLMTA 15 months of labor Authors from 12 countries 28 papers, including: o Global perspectives o Country and regional rollout o Implementation in a single lab o Mentorship o Special studies

Quantitative Quality Control Workshop Anna Murphy s personal mission to bridge the QC divide in the developing world

Quantitative Quality Control Workshop 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% N=25 (Day 1) estimated level of QC knowledge prior to taking this course (Day 7) estimated level of QC knowledge prior to taking this course Day 1 Day 7 Median 80% 30%

SLMTA 2: Breakthrough Curriculum Race to the Top 5 Stars Two workshops in 2015 April 13-24 October 19-30

Thinking Outside of the PEPFAR Piggy Banks Panama Canal, Panama Panama s Central Reference Laboratory Implemented SLMTA in 2012 showing great results Convinced top management to support their pursuit of ISO15189 accreditation Wrote a proposal to the national system of public investment (by Ministry of Economy and Finance) requesting $800,000 for the next 5 years Received $190,000 USD for year 1

SLMTA/SLIPTA Symposium 2014 November 28-29, 2014 Cape Town, South Africa A satellite meeting to the ASLM2014 Conference Thank you