Emerging Research Leaders Initiative Frequently Asked Questions

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Emerging Research Leaders Initiative Frequently Asked Questions 2017-2018

1. What is the Emerging Research Leaders Initiative? 2. What is an establishment grant? 3. Who are the partners? 4. Who is eligible to apply for an ERLI grant? 5. How will my application be reviewed? 6. Can an ERLI applicant apply to the Grant-in-Aid (GIA) competition? 7. How do you apply? 8. Will there be any other timeline extensions for applicants submitting to the Canadian National Transplant Research Program (CNTRP)? 9. Can an ERLI applicant submit more than one LOI to the overall ERLI competition? 10. How do you find out if your application has been successful? 11. Who should you contact at the Heart and Stroke Foundation if you have more questions? 12. Lay Reviewers and Structured Lay Summaries a. What is the role of lay reviewers on the Scientific Review Committee? b. What is a lay summary? How do you write one? c. Why is there a grade 10 language requirement for the structured lay summary? d. How do you test the grade level of your writing? e. How do you lower the grade level of your writing? f. Examples of Lay Summaries that follow the Foundation required format from Foundation funded researchers. 13. Under which circumstances would an award be terminated? 14. What are the 4 pillars of health research? 15. Where are application deadlines listed on your website? 16. What would be considered an incomplete or unacceptable application? 17. Will the HSF accept a scanned copy of an original signature? 18. What is the HSF s policy on indirect costs of research/overhead? Page 2 of 7

1. Q. What is the Emerging Research Leaders Initiative? A. The Emerging Research Leaders Initiative (ERLI) is an establishment grant program for researchers at the transition stage from post-doctoral fellow to early professional career stage in the areas of cardiovascular and/or cerebrovascular health research. This initiative aims to support successful early career launch of new investigators. Through this initiative, partners will provide establishment grant funds that will create a set of conditions conducive to the successful career launch of emerging research leaders in the cardiovascular and/or cerebrovascular health research domains. 2. Q. What is an establishment grant? A. Establishment grants are intended to assist new investigators in establishing independent health research programs and achieving the research productivity necessary to obtain major funding from national and other external granting agencies. 3. Q. Who are the partners? A. This multi-partnered initiative, led by the Heart and Stroke Foundation includes organizational partners from non-profit, government, industry, and emerging / existing networks. Partners include the New Brunswick Health Research Foundation, Pfizer Canada Inc., Fonds de recherche du Québec Santé (FRQS), the Canadian Stroke Prevention Intervention Network (C-SPIN) the Canadian Venous Thromboembolism Clinical Trials and Outcomes Research Network (CanVECTOR), the Canadian National Transplant Research Program (CNTRP), the Cardiac Arrhythmia Network of Canada (CANet), the Canadian Cardiovascular Society (CCS), and the Canadian Institutes of Health Research (CIHR). 4. Q. Who is eligible to apply for an ERLI grant? A. Applicants must have an MD, PhD, PharmD, DVM, or equivalent degree and a full-time academic or institutional teaching appointment in Canada as of July 1, the start date of the grant. Any applicant in an adjunct position must submit a letter from their dean/chair/division director to clarify their specific appointment, including the amount of protected time available and local infrastructure in place. This information can be included within the institutional support letter. At the time of the submission deadline (September 12, 2016), no more than five (5) years may have passed since the date of the first faculty appointment at the Assistant or Clinical Assistant Professor level or equivalent. This would include Adjunct positions in a research track for which the applicant is eligible to write a Grant-in-Aid/operating grant (as a Principal Investigator). At the time of submission, principal investigators are ineligible if they hold or have already held a nationally peer reviewed grant either as principal or co-principal investigator in the amount of $75,000 or more per year for a period of more than one (1) year. Applicants must also be a confirmed and/or recommended member of a ERLI Participating Network; for those applications in the heart disease and/or stroke field, this includes Canadian Stroke Prevention Intervention Network (C-SPIN),Cardiac Arrhythmia Network of Canada (CANet), the Canadian Venous Thromboembolism Clinical Trials and Outcomes Research Network (CanVECTOR), and/or the Canadian National Transplant Research Program (CNTRP). Further details regarding eligibility criteria can be found in the Emerging Research Leaders Submission Guidelines. 5. Q. How will my application be reviewed? A. All applications undergo peer review by HSF Scientific Review Committee and include expert reviewers that align with research areas of partner organizations. Page 3 of 7

6. Q. Can an ERLI applicant apply to the Grant-in-Aid (GIA) competition? A. Principal Investigators submitting an ERLI application to the Fall 2016 competition are allowed to submit no more than one (1) application (new and/or renewal) to the Fall 2016 HSF Grant-in-Aid (GIA) competition as a PI or co-pi. Recipients of an ERLI grant who are also successful in obtaining an open operating grant from HSF or another funding organization as a Principal Investigator (or co-principal Investigator) after the start of a funded ERLI grant will be allowed to keep the ERLI grant for the entire duration (if GIA and ERLI are awarded in tandem the applicant may only accept one award), provided there is no scientific or budgetary overlap with the research projects. ERLI grant recipients are required to inform funding organizations of any newly acquired operating grants. For information on multiple submissions or funded operating grant applications, please refer to the HSF Grant-in-Aid Submission Guidelines. (www.hsf.ca/research) 7. Q. How do you apply? A. There is a two stage approach: i) Letter of Intent (LOI) for Participating Network Applicants wishing to submit an application to the ERLI program must first submit a LOI to one of the participating networks for approval. This is to ensure that the proposed research program aligns with the objectives of the network. Timelines: July 15, 2016: August 12, 2016: Letter of Intent submission deadline to Participating Network* Notification of Letter of Intent stage; Invitations for full applications** * Except for the Canadian National Transplant Research Program (CNTRP). LOI deadline will be 29 July 2016 for CNTRP. ** Applicants will be notified in writing by the network whether the proposed program is relevant to the network. At that time, eligible applicants can submit a full application to the Heart and Stroke Foundation. ii) Full Application (by invitation only) Applicants successful in the LOI phase are invited to submit a full application. All full applications must be post-marked/courier stamped no later than September 12, 2016. 8. Q. Will there be any other timeline extensions for applicants submitting to the Canadian National Transplant Research Program (CNTRP)? A. No, the only timeline extension will be for applicants submitting a Letter of Intent (LOI) to CNTRP (see question 7a, i). All other timelines must be adhered to as described on page 3 in the 2017/18 ERLI Submission Guidelines. 9. Q. Can an ERLI applicant submit more than one LOI to the overall ERLI competition? A. No, an applicant may only submit one LOI to the overall ERLI competition. 10. Q. How do you find out if your application has been successful? A. Official letters will be sent to the applicants by April 2017. Offers will be made to the highest ranked applications, until the available pooled resources have been exhausted. Unspent Participating Network funds associated with this program cycle may be allocated to the next Participating Network-relevant application, above 4.0 but not offered funding through the pooled resources. 11. Q. Who should you contact at the Heart and Stroke Foundation if you have more questions? Page 4 of 7

A. If you have additional questions about the Emerging Research Leaders Initiative, you may contact Philip Bale, Special Initiatives Coordinator at (613) 691-4050 or pbale@hsf.ca. 12. Lay Reviewers and Structured Lay Summaries a. Q. What is the role of lay reviewers on the Scientific Review Committee? A. The HSF incorporates lay reviewers on its Scientific Review Committee (SRC) panels in order to increase accountability and transparency of the review process and to ensure that the research is aligned with its goals and mission. The HSF places a high priority on ensuring appropriate lay summaries are submitted as part of each application. If the application is accepted for funding and the lay summary is identified as unsatisfactory, funds will be encumbered pending receipt of a satisfactory lay summary. The lay reviewer reads the lay summary of each application and provides input on relevance to heart disease and/or stroke. The lay reviewer participates in the SRC meeting and comments on the applications. At this time, the lay reviewer does not vote or provide a rating for the applications. If the application is accepted for funding and lay summary is identified as unsatisfactory, funds will be encumbered pending receipt of a satisfactory lay summary. It is important that applicants ensure that all information on the application form is clear and concise and that the structured lay summary is completed with a clear explanation of how the research proposal is directly relevant heart disease and/or stroke. b. Q. What is a lay summary? How do you write one? A. A lay summary is a clear, plain language explanation of a research project or its outcomes. It provides a bigger picture context for the research and why it is important. A lay summary can be understood by the general public as well as researchers in other fields of study. For more tips on how to write one, please see the article Communicating Your Research in Lay Language. c. Q. Why is there a grade 10 language requirement for the structured lay summary? A. The lay summaries are not meant for researchers who readily read and understand scientific literature, they are for the lay reviewers to read and provide input on relevance to the broader community and the mandate of the Foundation. The lay reviewer must therefore be able to have a clear picture of the applicants proposed research. The lay summaries may also be used for communication purposes and must therefore be understood by the general public. d. Q. How do you test the grade level of your writing? A. Microsoft Word uses the Flesch-Kincaid grade formula and Flesch Reading ease formula to assess writing level. The Flesch-Kincaid grade formula calculates an overall reading grade level while the Flesch reading ease formula calculates a score of reading ease from 0-100, 100 being easier to read. Both Formulae use average sentence length (ASL- number of words divided by the number of sentences) and average syllables per word (ASW- number of syllables divided by the number of words). Please note that Microsoft Word readability statistics will not display a grade level greater than Grade 12. These formulae also work best with documents over 200 words. Some concepts can be more difficult than others to convey in lay language. The Flesch-Kincaid grade formula should be used to guide, but is not used by the Foundation in determining acceptable lay summaries. Follow these instructions for displaying readability statistics from Microsoft Word : Click the Microsoft Office Button (upper left corner of screen) Select Word Options Page 5 of 7

Select "Proofing" Check off spelling with grammar, as well as readability statistics options Notes: If you have set up Word to check the spelling and grammar of text in other languages, and a document contains text in multiple languages, Word displays readability statistics for text in the last language that was checked. For example, if a document contains three paragraphs the first in English, the second in French, and the third in English Word displays readability statistics for the third English paragraph only. For some European languages within an English document, Word displays only information about counts and averages, not readability. e. Q. How do you lower the grade level of your writing? A. Since the Flesch-Kincaid formulae use average sentence length (ASL- number of words divided by the number of sentences) and average syllables per word (ASW- number of syllables divided by the number of words) to calculate grade level, use more small sentences rather than a string of long sentences. Try using smaller words like tell, show and merge rather than identify, illustrate and integrate and use large technical words only when absolutely necessary. Generalize, simplify your grammar, use analogies, and omit sentences that do not add meaning. f. Examples of Lay Summaries that follow the HSFC s required format from HSF s funded researchers: Anonymous The anti-inflammatory role of a low molecular weight heparin lacking anticoagulant activity. Dr. Kathryn Todd Investigations of novel strategies to improve cellular and behavioral outcomes after focal embolic cerebral ischemia. Dr. J. Weitz Improving the effectiveness of thrombolytic therapy. 13. Q. Under which circumstances would an award be terminated? A. Awards may be terminated for a number of reasons including: misuse of funds, plagiarism, insufficient progress, or a lack of available funds. 14. Q. What are the 4 pillars of health research? A. The 4 pillars of health research, as defined by the Canadian Institutes of Health Research are: Basic Biomedical (I) Research with the goal of understanding normal and abnormal human function, at the molecular, cellular, organ system and whole body levels, including the development of tools and techniques to be applied for this purpose; developing new therapies or devices which improve health or the quality of life of individuals, up to the point where they are tested on human subjects. Studies on human subjects that do not have a diagnostic or therapeutic orientation. Clinical (II) Research with the goal of improving the diagnosis and treatment (including rehabilitation and palliation) of disease and injury; improving the health and quality of life of individuals as they pass through normal life stages. Research on, or for the treatment of, patients. Health Services/Systems (III) Page 6 of 7

Research with the goal of improving the efficiency and effectiveness of health professionals and the health care system, through changes to practice and policy. Health services research is a multidisciplinary field of scientific investigation that studies how social factors, financing systems, organizational structures and processes, health technologies, and personal behaviours affect access to health care, the quality and cost of health care, and ultimately Canadians health and well-being. Social, cultural, environmental and population health (IV) Research with the goal of improving the health of the Canadian population, or of defined subpopulations, through a better understanding of the ways in which social, cultural, environmental, occupational, and economic factors determine health status. 15. Q. Where are application deadlines listed on your website? A. Deadlines for grants/awards are located under Funding Opportunities / Deadlines. 16. Q. What would be considered an incomplete or unacceptable application? A. Examples of unacceptable or incomplete applications include, but are not limited to: Missing sections of the applications (e.g. research proposal, structured lay summaries, signatures, supervisors sections, etc) Missing letters (mentor, institutional support) Missing network letter of recommendation confirming membership and support for the application Missing any CVs (e.g. principle investigator, mentor) Submitted on old application form Not adhering to the font, margin and page limits Un-collated applications Faxed / Emailed applications Handwritten applications Not following instructions for electronic submission 17. Q. What constitutes an original signature? A. HSF will accept a scanned copy of the original signature or electronic signatures for the GIA and NPA programs. For the GIA program, the scanned copy of the original or electronic signature page must be uploaded into CIRCUlink. Applicants need not send an original copy of the signature page to HSF. (Note: The expectation is that an electronic signature will hold the same weight as an original (wet) signature.) 18. Q. What is the HSF s policy relating to indirect costs of research/overhead? A. The HSF supports only the direct costs of research. No funding is to be used for indirect costs of research. The definition of indirect costs of research for the purposes of this policy is, costs which cannot be directly associated with a particular research program or operating grant including costs associated with the general operation and maintenance of facilities (from laboratories to libraries); the management of the research process (from grant management to commercialization); and regulation and safety compliance (including human ethics, animal care and environmental assessment). Page 7 of 7