Analyzing academic laboratory accidents to prevent accidents Atlantic Basin Conference on Chemistry January 26, 2018

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Analyzing academic laboratory accidents to prevent accidents Atlantic Basin Conference on Chemistry January 26, 2018 Professor Craig Merlic Professor & Executive Director

UCLA - December 29, 2008 Sheharbano Sangji

Accident Aftermath Repercussions across UCLA campus University of California system Chemistry departments and universities nationwide Federal agencies Professional societies A very tragic accident that has had true impact improving safety practices and the culture of safety in ALL academic laboratories

UCLA Response UCLA initiated a wide array of changes in response to the accident, Cal/OSHA inspections, legal fillings, and the OSHA Lab Standard. Chancellor Vice Chancellor for Research Associate Vice Chancellor for Research Laboratory Safety Laboratory Safety Committees Environment, Health and Safety Departments Faculty Research Staff Graduate Students and Undergraduate Students Changes top to bottom were required to change the culture of safety

UCLA and University of California Sample Accomplishments EH&S approach completely changed to focus on research safety instead of mere compliance Dramatic increases in funding for safety by University of California UC Center for Laboratory Safety created UC promoted development of Chemical Protection lab coats 100% response rate to lab inspections by faculty 100% response rate for safety training by researchers Key Points: Responsibilities and expectations established for both faculty and lab workers Culture of safety created by acceptance of safety requirements and faculty engagement

But Before We Congratulate Ourselves Too Much There are still too many academic lab accidents!!!

Analysis of Safety Incidents UCLA Departments vs UC System vs Outside World What type of accidents are occurring? Where are accidents occurring? What are we doing right? What are we doing wrong? How do we compare against other universities? How do we compare against government labs? How do we compare against industry? How can incident data be used to drive safety interventions?

Safety Data and Challenges What Safety Data Can Be Collected? Safety training records Lab inspection reports Occupational injury reports Incidents with material damage, but no injuries Near miss data Safety Culture What are the Barriers to Safety Data Collection and Use? Lack of infrastructure and culture Lack of commitment and resources Quality of data Institutional reluctance to share or publicize data

Benefits of Analyzing Safety Data Reduce risks Impact safety culture Increase safety awareness Share safety information with the community Save money and resources Conduct safer and better research Improve productivity Predict (possibly) accidents

Safety Incidents in the UCLA Department of Chemistry and Biochemistry Low and decreasing incident rate, but aggregate identifies key injuries

Serious Explosion in September Hotplate failure overheats oil bath leading to explosion of pressure reactor resulting in serious injury to student. Third UC injury in recent years where student attempted to fix a runaway experiment. MUST TRAIN FOR EMERGENCIES!

Laboratory Injury Incidents at UCLA Laboratory accidents (~110) comprise only 8% of the 1300 accidents reported campus-wide each year Since 2011, continuous reduction in number of incidents OSHA recordable rate of 0.7/100 researchers Low, but can we do better to avoid the catastrophic accident? Lab Incidents 160 120 80 40 0 2008 2009 2010 2011 2012 2013 2014 2015 2016 Lacerations Needle sticks Burns Biohazard exposures Animal bites/scratches Chemical exposures Bodily trauma Slips and falls Ergonomic issues

Types of Laboratory Incidents since 2008 12% 13% 13% 16% 21% 16% Punctures and cuts Chemical exposure Strains acute & chronic (ergon.) Animal bites/scratches w/o expos Biohaz exposure Contusions/acute sprains Allergies Burns Unknown cause Other exposures Object in eye

Where Did the Incidents Occur? 61 Departments/Divisions 6 with more than 40 incidents 30% Div Lab Animal Med (Vivarium) Hematology Oncology Chemistry & Biochemistry 12% 4% 5% 4% 5% Neurology Pathology Microbiology

Safety Incidents at UCLA Department of Chemistry & Biochemistry (fourteen years): Lab-specific accident rate: 0.8% Overall accident rate: 1.6% UCLA Annual: Lab-specific incident rate: 1.5 % Overall UCLA accident rate: 3.0% State of California Annual: All industries including state/local governments accident rate: 4.0% Colleges, universities, professional schools accident rate: 2.9%. All manufacturing accident rate: 3.2% Chemical manufacturing accident rate: 2.8%

Chemistry & Biochemistry: Effect of Top-down Intervention 600 employees 14 12 10 8 6 4 2 0 2008 2009 2010 2011 2012 2013 2014 2015 2016 Intervention began in 2009 Increase in incidents 2010/11 Decrease as of 2012

Top-down Intervention Rigorous inspection of all labs, chemical storage rooms, shops and required follow up Departmental safety committee Mandatory FR lab coats Mandatory lab coats in all chemistry teaching labs Unannounced PPE inspections Mandatory reporting of all laboratory accidents PI laboratory safety training Extensive student and staff training Mandatory fire extinguisher training Documentation of training SOP for every hazardous chemical

Vivarium: Safety Pioneer Intervention Vivarium 50 40 30% 12% Pathology Incidents 30 20 10 0 2008 2009 2010 2011 2012 2013 2014 2015 2016 Two departments report the majority of UCLA lab incidents Significant reduction of incidents in Vivaria since 2010

Vivarium Incidents 2008-2016 (258 total) Lifting/overexertion, Contact with objects and falls, Animal bites account for most Lifting/ Overexertion 31% Contact w objects/ Animal Bites Falls 22% 12% 20 15 10 5 0 2008 2009 2010 2011 2012 2013 2014 2015 2016 Lifting/ Overexertion Contact w objects/falls Animal bites Downward trend since 2008

Vivarium Strategies for Reducing Injuries and Illnesses Hands-on animal restraining training 2 h class with focus on handling and restraining animals in a relaxed environment additional class time for uncomfortable students additional class time for teaching specific techniques Monthly safety meetings Financial support through EH&S and IRM

Impact of PI Safety Engagement on the Number of Injuries in the Lab Injuries witnessed or personally experienced by students and postdocs (n=406) 80% Major injuries Minor injuries Students and postdocs 60% 40% 20% 0% 0 1 to 2 3 to 5 0 1 to 2 3 to 5 6+ Lab Injuries PI monitors lab safety PI may or may not check safety PI does not monitor lab safety Key Points: Faculty Engagement Setting Expectations I. Schröder, D.Y.Q. Huang, O. Ellis, J. H. Gibson, N. L. Wayne; J Chem Health and Safety, 2015

Conclusions: Reducing Accidents There is no magic bullet A sustained and multipronged set of actions is required Rigorous expectations (Top-Down Approach) is effective Further reductions in accident rates must still be made Changing the routine (Safety Pioneer Approach) is effective May or may not be readily transportable or scalable Engagement by faculty is the most effective action with a documented impact on safety Active participation by direct supervisors reduces injuries and promotes a culture of safety

Acknowledgements Dr. Imke Schroeder (UCLA, UCCLS) Dr. Nancy Wayne (UCLA, UCCLS) Dr. Elizabeth Czornyj (UCLA, UCCLS) Dr. Michael Blayney (Northwestern Univ, STC) Advisory Board, UC Center for Laboratory Safety Advisory Board, Safety Training Consortium UCLA EH&S UC Enterprise Risk Management