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Thursday, July 17, 2014 11:30 a.m. Eastern Dial-In: 1.888.863.0985 Conference ID: 62918492 Slide 1

Robyn D Oria MA, RNC, APC, is the Executive Director at the Central Jersey Family Health Consortium in North Brunswick, New Jersey. Jill Mhyre, MD, is an Associate Professor of Anesthesiology at the University of Arkansas for Medical Sciences in Little Rock, Arkansas. Slide 2

Disclosures Robyn D Oria, MA, RNC, APC has no actual or perceived conflict of interest in relation to this presentation. Jill Mhyre, MD has no actual or perceived conflict of interest in relation to this presentation. Slide 3

Objectives This session will provide: Systems solutions to identify and treat women who may be developing critical illness, including The Modified Early Obstetric Warning System (MEOWS) and The Maternal Early Warning System (MEWS) Tips on when to communicate assessment parameters that fall outside of norms Escalation policies to ensure timely bedside evaluation and treatment for those women who need it Implementation considerations to maximize efficacy of The Maternal Early Warning System Slide 4

Slide 5

Rationale In many cases in this report, the early warning signs of impending maternal collapse went unrecognized. Why? These events are relatively rare The childbearing population is mostly healthy The normal physiologic changes of pregnancy Slide 6

California Pregnancy Associated Mortality Review 2002-2005 Delayed response to triggers Preeclampsia 92% Postpartum hemorrhage 85% Cerebrovascular disease 63% Venous thromboembolism 75% Amniotic fluid embolism 67% Slide 7

The United States Joint Commission requires hospitals to have written criteria to observe change or deterioration in a patient condition and how to recruit staff to manage patient care. Joint Commission Sentinel Event Alert, Issue 44: Preventing Maternal Death (2010) Slide 8

National Partnership for Maternal Safety Goals 1. To reduce maternal morbidity and mortality in the US by 50% 2. To reduce racial and ethnic maternal health disparities Main EK. (2013). Maternal Mortality: Time for National Action. Obstet Gynecol, 122, 735-736. Slide 9

D Alton, ME. (2014). National Partnership for Maternal Safety. Obstet Gynecol, 123, 973-977. Slide 10

What are Early Warning Signs? Early warning signs are... a set of predetermined calling criteria (based on periodic charting of vital signs) as indicators of the need to escalate monitoring or call for assistance Mackintosh, N. (2014). Value of a modified early obstetric warning system (MEOWS) in managing maternal complications in the peripartum period: an ethnographic study BMJ Qual Saf, 23, 26-34. Slide 11

Two Essential Components Maternal Early Warning Criteria Effective Escalation Policy Slide 12

Modified Early Obstetric Warning System (MEOWS) Contact doctor if one red or two yellow scores at any one time. Lewis G. (2007). Saving Mothers Lives. Swanton RD. (2009). A national survey of obstetric early warning systems in the United Kingdom. Int J Obstet Anesth, 18, 253-257. Slide 13

Singh S. (2012). A validation study of the CEMACH recommended modified early obstetric warning system (MEOWS). Anaesthesia 67, 453. Slide 14

Outcomes Pulmonary embolism Cerebral venous sinus thrombosis Intracranial bleed Status epilepticus DKA Myocardial infarction Pulmonary edema Anesthetic complications Singh S. (2012). A validation study of the CEMACH recommended modified early obstetric warning system (MEOWS). Anaesthesia 67, 453. Slide 15

Results 673 patients scored 200 (30%) triggered an evaluation 86 (13%) met criteria for morbidity Sensitivity 89% Specificity 79% Positive Predictive Value 39% Negative Predictive Value 98% Singh S. (2012). A validation study of the CEMACH recommended modified early obstetric warning system (MEOWS). Anaesthesia 67, 453. Slide 16

Maternal Early Warning Criteria Systolic BP; mmhg <90 or >160 Diastolic BP; mmhg >100 Heart rate; beats per min <50 or >120 Respiratory rate; breaths per min <10 or >30 Oxygen saturation; % <95 room air, sea level Oliguria; <35 ml/hr for 2 hours Slide 17 Mhyre, JM. (In press). Obstet Gynecol.

Maternal Early Warning Criteria Maternal agitation, confusion, or unresponsiveness Patient with hypertension reporting a nonremitting headache or shortness of breath Clark SL. (2012). Preventing maternal death: 10 clinical diamonds. Obstet Gynecol, 119, 360-364. Slide 18

Measurement Artifact A single abnormal vital sign can reflect measurement artifact Verify isolated abnormal measurements HR, BP, RR, SpO 2 Urgent bedside evaluation is usually indicated if: Any value persists for more than one measurement Values present in combination with additional abnormal parameters Value recurs more than once Slide 19

Immediate Action Required Systolic BP; mmhg <90 or >160 Diastolic BP; mmhg >100 Heart rate; bpm <50 or >120 Respiratory rate; bpm <10 or >30 Oxygen saturation; % <95 Oliguria; ml/hr x 2h <35 Maternal agitation, confusion, or unresponsiveness Patient with hypertension reporting a nonremitting headache or shortness of breath Slide 20

Case Illustration 34 year old recovering from cesarean delivery in the PACU Nausea, vomiting, diaphoresis Slide 21

140 120 100 80 60 Slide 22

Effective Escalation Policy An abnormal parameter would require: 1) Prompt reporting to a physician or other qualified clinician 2) Prompt bedside evaluation by a physician or other qualified clinician with the ability to activate resources in order to initiate emergency diagnostic and therapeutic interventions as needed Slide 23

4 Implementation Principles 1) Every hospital should have A warning system, we are not developing THE standard US early warning system 2) Plans are nothing; planning is everything. -Dwight D Eisenhower 3) Multi-disciplinary team work is key for the development, maintenance and daily use of the warning systems 4) Simplicity is critical for success Slide 24

Need to define: Local Implementation 1) Who to notify 2) How to notify them 3) How rapidly to expect a response 4) When and how to activate the clinical chain of command in order to ensure an appropriate response Slide 25

Streamline Communication Task shifting Mobile communication devices Automated paging systems Abbreviated communication (e.g., SBAR) A well-established normative expectation for bedside evaluation Team training (e.g., TeamSTEPPS) Slide 26

Why Bedside Evaluation Maternal mortality reviews repeatedly identify the lethal consequences of phonebased management in women developing critical illness Slide 27

Evaluating Clinician Anesthesiologist Primary Obstetric Provider MFM Laborist Family MD Nurse Anesthetist Patient Bedside Nurse Nurse Midwife Emergency Physician Rapid Response Team Hospitalist Intensivist Slide 28

Differential Diagnoses Common vs. rare life-threatening diagnoses Hypertension (SBP>160 or DBP>100) Hypotension (SBP<90) Tachycardia (HR>120) Bradycardia (HR<50) Tachypnea (RR>30) Bradypnea (RR<10) Hypoxemia (SpO 2 <95% on room air) Oliguria (<35 ml/hr for >2 hrs) Confusion, agitation, or unresponsiveness Slide 29

What are appropriate outcomes for a bedside evaluation? When the bedside evaluation is non-diagnostic, or when clinicians suspect that a particular MEW criterion reflects normal physiology for that patient The team should establish a tailored plan for subsequent monitoring, notification and clinical review Slide 30

What are appropriate outcomes for a bedside evaluation? Recurrent MEW criteria Increase the intensity and frequency of monitoring Increase the frequency of evaluation Initiate resuscitative and diagnostic interventions Carefully consider the appropriate differential until a diagnosis is confirmed, or until the criteria resolve Slide 31

What are appropriate outcomes for a bedside evaluation? Diagnosed as critically ill or a high likelihood of developing critical illness Initiate appropriate resuscitative, diagnostic and therapeutic interventions Escalate level of care Obstetric emergency response teams Rapid response teams Transfer to a higher acuity setting Slide 32

Summary Delays in diagnosis contribute to a large portion of preventable maternal deaths Maternal Warning Criteria and Escalation Policy Prompt reporting and bedside evaluation Local implementation details Cut-points Who to notify, how to notify them How quickly to expect a response Back-up systems to ensure timely evaluation Slide 33

Q&A Session Press *1 to ask a question You will enter the question queue Your line will be unmuted by the operator for your turn A recording of this presentation will be made available on our website: www.safehealthcareforeverywoman.org Slide 34

Next Safety Action Series Quantifying Blood Loss Date and Time To Be Determined Renee Byfield, MS, RN, FNP, C-EFM Nurse Program Development Specialist Association of Women s Health, Obstetric and Neonatal Nurses David Lagrew, MD, FACOG Medical Director of Physician Informatics & Chief Integration and Accountability Officer MemorialCare Health System Slide 35