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CEDARS-SINAI HYPERTENSION CENTER 2016 Clinical Highlights Symposium FRIDAY, FEBRUARY 26, 2016 7:15 A.M. TO 3:15 P.M. CONFERENCE LOCATION Harvey Morse Conference Center 8701 Gracie Allen Drive Plaza Level, South Tower American Society of Hypertension Certified Comprehensive Hypertension Center www.cedars-sinai.edu/hypertension For the latest course information and to register visit csmc.edu/cme and click on CME courses.

8797 Beverly Blvd., Suite 250 Register Now for: CEDARS-SINAI HYPERTENSION CENTER 2016 Clinical Highlights Symposium FRIDAY, FEBRUARY 26, 2016 7:15 A.M. TO 3:15 P.M. Earn up to 6.25 AMA PRA Category 1 Credits NON-PROFIT ORG. U.S. POSTAGE PAID Los Angeles, CA Permit #22328

ACTIVITY INFORMATION COURSE DESCRIPTION AND STATEMENT OF NEED Hypertension remains the leading preventable cause of cardiovascular disease and death in the world. The inaugural Cedars-Sinai Hypertension Center 2016 Clinical Highlights Symposium will provide participants with a comprehensive review of the latest diagnostic and therapeutic approaches to this complex and multifaceted disease, using a case-based approach. Course content will include an update on the latest evidence from recent landmark clinical trials and state-of-the-art approaches to the diagnosis and management of hypertension in clinical practice. Topics will include the landmark SPRINT trial, drug and non-drug therapy, drug-resistant hypertension (including percutaneous intervention), adrenal hypertension, renal and renovascular hypertension. The course format will be case-based lectures reviewing the latest evidence, recommendations and scientific principles to guide therapy for a wide-range of ambulatory patients with hypertension. The Cedars-Sinai Hypertension Center is the only hypertension program in California to be certified as a Comprehensive Hypertension Center by the American Society of Hypertension (ASH)-the largest organization of clinical hypertension specialists and hypertension investigators in the United States. The Cedars-Sinai Hypertension Center provides comprehensive multi-specialty consultative care for patients with difficult-to-treat hypertension, secondary hypertension, and related conditions. The Center also has innovative National Institutes of Health (NIH)-funded research programs ranging from basic science on the immunologic basis of hypertension to a randomized clinical trial of a community-based barber-pharmacist-physician team approach to improve hypertension management in African-American men. TARGET AUDIENCE This course is designed for Internists, Family Medicine, Hospitalists, General Medicine, Pediatrics, Nephrologists, Cardiologists, Endocrinologists, OB/GYN, Pharmacists, Nurses, Nurse, Practitioners, Physicians Assistants, and interested allied healthcare providers. EDUCATIONAL OBJECTIVES Review the history of hypertension, current approaches and future trends Describe the most accurate methods of blood pressure monitoring for diagnosis and management of hypertension Describe the basic approaches to pharmacological management of hypertension, including resistant hypertension Review current methods in the diagnosis of pheochromocytoma and paraganglioma and approaches to treatment Describe the role of aldosterone in the pathophysiology and treatment of high blood pressure Apply culturally appropriate interventions and counseling on blood pressure and treatment adherence among minority patient populations Summarize treatment strategies for hypertension in patients with chronic kidney disease Recognize the importance of hypertensive heart disease as cardiovascular risk factor and implement specific treatment strategies for blood pressure control and cardiovascular risk reduction in patients with hypertensive heart disease Counsel patients regarding lifestyle changes to prevent or reduce the risk of hypertension Develop a comprehensive plan of care and monitoring for patients with diabetes, metabolic syndrome and other endocrine disorders Describe the unique management challenges in diagnosing and treating renovascular hypertension ACCREDITATION STATEMENT is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. CREDIT DESIGNATION STATEMENT designates this live activity for a maximum of 6.25 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. NURSES The California State Board of Registered Nursing accepts courses approved by the ACCME for category 1 credit as meeting the continuing education requirements for license renewal. TRAINING / CREDIT DISCLAIMER STATEMENT While offering CME credit, this course is not intended to provide extensive training for certification in the field. Approval of category 1 credit by should not be construed as endorsement of any product. POLICY ON DISCLOSURE It is the policy of to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. assesses conflict of interest with its faculty, planners and managers of CME activities. Conflicts of interest that are identified are resolved by reviewing that presenter s content for fair balance and absence of bias, scientific objectivity of studies utilized in this activity, and patient care recommendations. While endeavors to review faculty content, it remains the obligation of each physician or other healthcare practitioner to determine the applicability or relevance of the information provided from this course in his or her own practice. ACKNOWLEDGMENT OF COMMERCIAL SUPPORT Commercial support for this conference is pending and will be acknowledged at the conference. We gratefully acknowledge the educational support received from the Sheila Kar Health Foundation whose mission is to improve our community s health by spreading and promoting education about health practices and disease prevention.

AGENDA CEDARS-SINAI HYPERTENSION CENTER 2016 Clinical Highlights Symposium FRIDAY, FEBRUARY 26, 2016 7:15 A.M. Registration and Continental 8:00 Welcome Remarks 8:05 Hypertension: Yesterday, Today and Tomorrow 9:00 Initial Evaluation for Hypertension and Ronald Victor, MD Michael Weber, MD Stanley Franklin, MD State-of-the-Art Blood Pressure Monitoring Ronald Victor, MD 9:30 A Practical Approach to Hypertension Pharmacotherapy 10:00 Break 10:15 Diabetes, Hypertension and Metabolic Syndrome 10:45 Pheochromocytoma and Paraganglioma 11:15 Primary Aldosteronism 11:45 Lunch 12:15 P.M. Renovascular Hypertension Vito Campese, MD 12:45 Hypertensive Heart Disease Florian Rader, MD 1:15 Break 1:30 Lifestyle Modification and Non-Drug Therapy 2:00 Hypertension in African-Americans Michael Weber, MD Run Yu, MD, PhD Odelia Cooper, MD Sheila Kar, MD Anthony Reid, MD and Minority Populations 2:30 Hypertension in Chronic Kidney Disease Vito Campese, MD 3:00 Closing Remarks Ronald Victor, MD 3:15 P.M. Adjourn ACTIVITY DETAILS CONFERENCE LOCATION 8701 Gracie Allen Drive Harvey Morse Conference Center Plaza Level, South Tower PARKING Self-parking is available in parking lots 1, 2 and 4.

FACULTY COURSE DIRECTOR Ronald G. Victor, MD Director, Cedars-Sinai Hypertension Center Associate Director, Cedars-Sinai Heart Institute Burns and Allen Chair in Cardiology Research Professor of Medicine STEERING COMMITTEE MEMBERS Stanley S. Franklin, MD Nephrologist Department of Medicine *ASH Clinical Hypertension Specialist Sheila Kar, MD, FACC Cardiologist & Past-Clinical Chief Cedars-Sinai Heart Institute Florian Rader, MD, MSc Assistant Professor of Medicine Co-Director of Clinic for Hypertrophic Cardiomyopathy and Aortopathies Cardiologist Cedars-Sinai Hypertension Center and Heart Institute Anthony Reid, MD Cardiologist KEYNOTE SPEAKERS Vito M. Campese, MD Professor of Medicine Division Chief, Department of Nephrology Keck School of Medicine at USC Los Angeles, CA Michael A. Weber, MD, FACP, FACC, FAHA Professor of Medicine and Associate Dean for Research SUNY Downstate College of Medicine Brooklyn, NY COURSE FACULTY Odelia B. Cooper, MD Assistant Professor of Medicine Division of Endocrinology, Diabetes & Metabolism Pituitary Center Run Yu, MD, PhD Co-Director, Carcinoid and Neuroendocrine Tumor Center Attending Staff Physician Division of Endocrinology, Diabetes, and Metabolism * ASH (American Society of Hypertension)

REGISTRATION Cedars-Sinai Hypertension Center 2016 Clinical Highlights Symposium FEBRUARY 26, 2016 REGISTRATION FEES PHYSICIAN **ALLIED HEALTH *RESIDENT/FELLOW PROFESSIONAL Received by 2/5/16 $150 $75 free Received after 2/5/16 $175 $100 $25 *Residents/Fellows are eligible to attend at no charge or for a reduced registration fee. For this reduced fee, please send the written proof of residency (i.e. letter from Program Director) along with your completed registration form or upload the written proof of residency online. ** Nurses; Nurse Practitioners; Physicians Assistants; Pharmacists; etc. REGISTRATION METHODS ONLINE registration: csmc.edu/cme and click on CME Courses MAIL form to: Office of Continuing Medical Education Attn: Registration 8797 Beverly Boulevard, Suite #250 FAX form to: 310-423-8596 For additional course or registration information call 310-423-5548. Please print clearly LAST NAME FIRST NAME DEGREE SPECIALTY ADDRESS CITY STATE ZIP PHONE FAX EMAIL * An email address is required to register for the conference. CHECK ENCLOSED PAYABLE TO CSMC FOR $ PLEASE CHARGE MY CREDIT CARD VISA MASTERCARD AMEX FOR $ CC NUMBER CCV EXP DATE / AUTHORIZED SIGNATURE HOW DID YOU LEARN ABOUT THIS CME ACTIVITY? Brochure/Other Printed Materials Cedars-Sinai Website Email Internet Search Colleague Past Participant Internal Cedars-Sinai Communication Other CONFIRMATION In order to receive a registration confirmation, please provide your e-mail address. If you do not receive a confirmation, please call 310-423-5548 to confirm your registration. REFUND POLICY All cancellations must be submitted in writing and refunds will be subject to a $40 administrative charge. No refunds will be given after February 12, 2016. CANCELLATION POLICY Cedars-Sinai reserves the right to cancel or reschedule programs due to circumstances beyond its control or close registration when programs are oversubscribed. Registrants are advised against purchasing nonrefundable airline tickets until they receive registration confirmation. Cedars-Sinai is not responsible for penalties incurred as a result of cancelled transportation costs.