Introduction to Bioterrorism. Acknowledgements. Bioterrorism Training and Emergency Preparedness Curriculum

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Bioterrorism Training and Emergency Preparedness Curriculum College of Health Northwest and Human Center for Services Public Health Practice Long Beach, University CA of Washington School of Public Health and Community Medicine 1 Acknowledgements This curriculum is a collaborative effort among the four departments in the College of Health and Human Services namely, Health Science, Health Care Administration, Nursing, and Professional Studies. Thanks to our project collaborators, to all those who provided feedback on the content, material selection and/or technical assistance, to our consultants, our website designers and developers, and most of all to OUR STUDENTS for their untiring work, persistence and patience in helping to bring this project together. UW California Northwest Center State for University, Public Health Long Practice Beach 2 Introduction to Bioterrorism 3 1

Intro to Bioterrorism Learning Objectives Define bioterrorism (BT) Describe the potential characteristics of a BT event Describe the general public health response to a BT event Identify and describe your potential roles and responsibilities in a BT event 4 What Is Bioterrorism? Definition Terrorism (FBI definition): "The unlawful use of force or violence against persons or property to intimidate or coerce a government, the civilian population, or any segment of it, in furtherance of political or social objectives." 5 What Is Bioterrorism? Definition The intentional use of micro-organisms or toxins derived from living organisms to produce death or disease in humans, animals, or plants The goal of bioterrorism is to produce fear in the population with subsequent disruption of society 6 2

What Is Bioterrorism? Potential An overt attack is announced. Resembles the traditional HAZMAT event: Response to explosives and chemical exposures. First responders are likely to be traditional firstresponders: fire, HAZMAT, police. 7 What is Bioterrorism? Definite A covert attack is unannounced. Thought to be likely scenario bioterrorism. with First responders are likely to be health care providers, including Emergency Departments, primary care physicians, and hospitals. 8 History of Bioterrorism Biological warfare (BW) employed as far back as 6th century BC. Examples of past BW: 14th Century: Mongols catapulted corpses with bubonic plague over walls into Crimea. 15th Century: Pizarro presented native South Americans with smallpox-contaminated clothing. 1940: Japan s Unit 731 dropped plague-infected fleas over Manchuria & China. 9 3

History of Bioterrorism Recent Examples 1984: Rajneeshee Cult contaminated restaurant salad bars with Salmonella typhimurium. 1995: Aum Shinrikyo cult attempted unsuccessfully to disperse BW agents in aerosol form; sarin gas attack in Tokyo. 2001: Anthrax-contaminated letters to U.S. media and government offices. 10 History of Bioterrorism State-sponsored Bioweapons Research 1972 Biological Weapons Convention Treaty prohibiting stockpiling and research into biological agents for offensive purposes Ratified by >140 countries Not adhered to in some countries (former Soviet Union) United States Bioweapons program Offensive program: 1943-1969 Defensive program: 1953-today at USAMRIID 11 Recognition of a BT Event Surveillance/Detection Goal: Detect unusual medical events sooner rather than later Depends on ability to identify a greater than expected number of cases or syndromes Requires sensitivity to unusual clusters of disease syndromes compatible with naturally occurring or BT-related outbreaks 12 4

Recognition of a BT Event General Characteristics non- Many agents initially produce a specific and/or flu-like illness Aerosol dissemination Not detectable: odorless, colorless, tasteless Particle size 1-5um Potential wide-spread dissemination May require special treatment approach 13 Recognition of BT Event Epidemiologic Clues I Increase in persons ill with a similar or unusual syndrome Increase in unexplained disease or deaths Single case of disease due to an uncommon agent Unexpected geographic or seasonal distribution of disease Unusual age distribution e.g., varicella, measles in adults 14 Recognition of BT Event Epidemiologic Clues II Illness in persons with common ventilation system or other exposure Atypical route of transmission e.g., aerosol botulism Unusual illness among animals preceding or accompanying human illness Failure to respond to usual antibiotic therapy 15 5

Recognition of BT Event Surveillance/Detection By California State statute Medical Examiner (Government Code, State of California section 27491) 16 Recognition of BT Event Surveillance/Detection Effective September 2000, the following are immediately reportable to the local health jurisdiction All suspected illnesses caused by potential bioterrorism agents Unexplained critical illness or death Rare diseases of public health importance 17 Public Health Response to a BT Event General Characteristics Old skills applied in new ways Disease/illness investigation Informing and educating the public Providing medications and immunizations Referring and connecting people to resources Informing and educating health care workers Enforcing laws that protect the public s health Coordinating activities with other agencies 18 6

Public Health Response to a BT Event General Characteristics with a few additional factors Coordination of activities with local law enforcement and FBI Preservation of evidence Early notification and involvement of federal health officials Epidemiologic characteristics of disease may differ from typically expected 19 Key Preparedness Elements Hazard Analysis Determining what emergencies might occur & the availability of local resources for emergency response Emergency Response Planning Health Surveillance and Epidemiologic Investigation Monitoring the health status of the community & investigating when it differs from expected 20 Key Preparedness Elements Laboratory Diagnosis and Characterization Identifying the cause of illness Consequence Management Responding to the emergency Immediate response & long-term recovery 21 7

Potential Roles for Public Health Workers in BT Response: Clinical Staff Dispensing mass antibiotic prophylaxis Administering mass immunizations Triaging (e.g., phone calls or clinic visits) and referring individuals as appropriate Referring individuals to social support and informational resources General counseling and reassurance of anxious clients Assisting in conducting interviews during disease investigations and follow-up 22 Potential Roles for Public Health Workers in BT Response: Epidemiologists and Communicable Disease Staff Assisting communicable disease epidemiologists in disease investigation: Case interviewing and data collection Data entry and analysis Case contact tracing and identification Case follow-up 23 Potential Roles for Public Health Workers in BT Response: Public Health Leaders Emergency response planning Activation of the emergency response plan Supervising and coordinating public health efforts Coordination and communication with other agencies Providing information to the media and general public Risk communication 24 8

Potential Roles for Public Health Workers in BT Response: Public Health Information Staff Educating and informing the public on BT health risks and response efforts (including dispelling myths) Assisting in the development of press releases Referring individuals to social support and informational resources General counseling and reassurance of anxious clients 25 Potential Roles for Public Health Workers in BT Response: Assessment Coordinators Assisting communicable disease epidemiologists in disease investigation Assisting in the creation and dissemination of press releases, health alerts, and other informational resources Coordination and communication with other agencies Identifying populations in the community that may require special services in the event of an emergency 26 Potential Roles for Public Health Workers in BT Response: Technical and Support Staff Answering phone calls Delivering critical baseline information Referring calls as appropriate Assisting in the creation and dissemination of press releases, health alerts, and other informational resources Arranging sites for delivery of mass immunizations or antibiotics Coordinating delivery of lab specimens 27 9

Potential Roles for Public Health Workers in BT Response: Environmental Health Environmental health risk assessment Food and water inspection Assisting in illness investigation 28 Introduction to Bioterrorism Summary of Key Points A bioterrorist attack is likely to be covert. First responders in a covert attack are likely to be health care providers. Public health workers will use many of the same skills in response to a bioterrorism incident as they do in a routine workday. The manner in which job skills are implemented will potentially differ from a routine workday. 29 Resources Centers for Disease Control & Prevention http://www.bt.cdc.gov Federal Emergency Management Agency http://www.fema.gov Johns Hopkins Center for Civilian Biodefense Studies fact sheets and links to other info, including JAMA series from Working Group on Civilian Biodefense http://www.hopkins hopkins-biodefense.org/ USAMRIID http://www.usamriid usamriid.army.mil 30 10

Resources Long Beach Public Health Department http://www.ci.long-beach.ca.us (562) 570-7999 Los Angeles County http://www.lapublichealth.org/ California State Department of Health Services http://www.dhs.ca.gov/ Division of Communicable Disease Control 1-510-540-2566 (regular business hours) OR 1-800- 971-9631 (24 hour emergency) 31 Resources State of California Emergency Preparedness Office http://www.dhs.ca.gov/epo/epoindex.htm Los Angeles County Department of Public Health 800-397-3993 (communicable disease reporting system) http://lapublichealth.org/acd/cdrs.htm or To report a possible bioterrorist incident contact ACDC Bioterrorism and Response at 213-240-7941 32 In Case of An Event Web Sites with Up-to-Date Information and Instructions Centers for Disease Control and Prevention http://www.bt bt.cdc.gov/emcontact/index.asp Level A Lab Protocols: Presumptive Agent ID http://www.bt bt.cdc.gov/labissues/index.asp 33 11

In Case of An Event Web Sites with Up-to-Date Information and Instructions FBI Terrorism Web Page http://www.fbi fbi.gov/terrorism/terrorism. /terrorism/terrorism.htm Mail Security http://www.usps.com/news/2001/press/serviceupdates.htm NIOSH Worker Safety and Use of PPE http://www.cdc.gov/niosh/emres01.html 34 12