BECKMAN YOUNG INVESTIGATOR PROGRAM

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BECKMAN YOUNG INVESTIGATOR PROGRAM [Research Support for Promising Young Faculty] January 24, 2018 October 2017 Room 238, Strom Thurmond Institute

INTRODUCTION TO ORD AND CFR OFFICE OF RESEARCH DEVELOPMENT (ORD) Research Division CORPORATE & FOUNDATION RELATIONS Development and Alumni Relations Division SEZ ATAMTURKTUR JANE JACOBI KELLY MCSWAIN Assistant Vice President of Research; Director, Office of Research Development Research Associate, Office of Research Development Program Manager, Office of Research Development ANNE BARR Sr. Director of Corporate Relations AMBER PADGETT Development Coordinator - Corporate and Foundation Relations E: sez@clemson.edu E: jacobij@clemson.edu E: kmcswai@clemson.edu E: eabarr@clemson.edu E: day6@clemson.edu P: 864-656-3003 P: 864-656-1296 P: 864-656-0260 P: 864-318-2930 P: 864-656-2247

OVERVIEW OF THE BECKMAN FOUNDATION The Arnold and Mabel Beckman Foundation was established in 1977 by the late Arnold and Mabel Beckman. Arnold Beckman founded Beckman Instruments in 1935 with the production of a ph meter he invented. The Arnold and Mabel Beckman Foundation has more than $562 million in assets and awards approximately $27 million in grants annually. The Beckman Foundation provides grants to researchers in chemistry and life sciences to promote scientific discoveries and particularly to foster the invention of methods, instruments, and materials that will open up new avenues of research. The Foundation has four major grantmaking programs: Beckman Scholars, Beckman Young Investigator Award, Beckman Postdoctoral Fellows, and the Beckman-Argyros Vision Research Award.

BECKMAN YOUNG INVESTIGATOR PROGRAM The Beckman Young Investigator Program (BYI) provides research support to the most promising young faculty members in the early stages of their academic careers in the chemical and life sciences, particularly to foster the invention of methods, instruments and materials that will open up new avenues of research in science. Projects proposed for the BYI program should be innovative, high-risk, and show promise for contributing to significant advances in chemistry and the life sciences. Proposed research that cuts across traditional boundaries of scientific disciplines is encouraged. Proposals that already have substantial funding (more than $225K in direct funding during any BYI program year) will not be considered for the BYI award. Projects are normally funded for a period of four years in the range of $600K. The Foundation does not provide for indirect costs. The application window for the Beckman Young Investigator program is typically June-September.

BECKMAN YOUNG INVESTIGATOR PROGRAM: ELIGIBILITY Faculty within the first three years of a tenure-track position are eligible for this program. For the 2019 program, tenure track start date must be after 8/14/2015. Candidates must be citizens or permanent residents of the United States at the time of application. Persons who have applied for permanent residency but have not received their government documentation by the time of the application are not eligible. No individual may apply for a Beckman Young Investigator award more than two times. Investigators can have no more than $225K in direct, annualized external funding grants during any BYI program year (August-July) at time of application. Start-up funds, department-wide instrumentation grants and Transition grants (such as NIH K99/R00) are not counted toward this total.

RECENT BECKMAN YOUNG INVESTIGATOR WINNERS 2017 Victor Acosta University of New Mexico Department: Physics Research Title: Magnetic resonance spectroscopy on a diamond chip Jeremy Baskin Cornell University Department: Chemistry and Chemical Biology Research Title: Synthetic lipid biology: Membrane engineering via controlled phospholipid synthesis in vivo Pamela Chang Cornell University Department: Microbiology and Immunology Research Title: Chemical technologies for elucidating and controlling inflammation Jose Rodriguez University of California Los Angeles Department: Chemistry and Biochemistry Research Title: Frontier approaches in electron cryo-diffraction to reveal atomic views of complex macromolecular assemblies Dan Fu University of Washington Department: Chemistry Research Title: Quantitative single cell phenotypic imaging of multicellular systems Erik Grumstrup Montana State University Department: Chemistry and Biochemistry Research Title: Superresolution optical strategies for revealing ultrafast carrier-phonon dynamics in nanoscale materials Ali Faih Sarioglu Georgia Tech Department: Electrical and Computer Engineering Research Title: All-electronic lab-on-a-chip platforms for highthroughput multi-modal cell phenotyping Bo Want Stanford University Department: Bioengineering and Developmental Biology Research Title: Unfolding germline development in the human parasite schistosoma using nanoscale tools

RECENT BECKMAN YOUNG INVESTIGATOR WINNERS 2016 Yiyang Gong Duke University Department: Biomedical Engineering Research Title: Optical brain machine interface for neural circuit dissection Markita Landry University of California Berkeley Department: Chemical and Biomolecular Engineering Research Title: Linking chemistry to behavior: Long-term optical monitoring of neurotransmission Zachary Pincus Washington University St. Louis Department: Developmental Biology and Genetics Research Title: The origins of individuality: Developmental determinants of health and lifespan Gabriela Schlau-Cohen MIT Department: Chemistry Research Title: Uncovering action at the nanoscale Sabrina Spencer University of Colorado at Boulder Department: Chemistry and Biochemistry Research Title: Single-cell approaches for a priori indentification of drug-resistant cancer cells Scott Warren University of North Carolina Chapel Hill Department: Chemistry Research Title: Broadband biosensing from the visible to infrared with 2D plasmonic metamaterials Jing-Ke Weng Whitehead Institute for Biomedical Research Department: Biology Research Title: Exploring and exploiting firefly and coelenterate luciferin biosynthesis Ke Xu University of California Berkeley Department: Chemistry Research Title: Proving intracellular physiochemical processes at the nanometer scale, one molecule at a time

COMMON CHARACTERISTICS OF BYI WINNERS (2016 & 2017) Average h-index: 16 (range 10-24) Average number of citations: 1,517 (range 466-3110) Other awards received before Beckman Young Investigator Award: Burroughs Wellcome Fund Career Award NARSAD Young Investigator Award Smith Family Award for Excellence in Biomedical Research Searle Scholar Award Kimmel Scholar Award Alfred P. Sloan Fellowship Pew Scholar in Biomedical Sciences Award

WHAT WE VE LEARNED FROM THE FOUNDATION Of the LOIs submitted, 100 are typically invited to submit a full application. The Foundation plans to fund 10 awards this year. From the 100 applicants who are invited to submit full proposals, 14 are invited to come out to the Foundation (California) for an interview and presentation. The Foundation is looking to fund investigators who are articulate, passionate, and can clearly demonstrate how a BYI award would help them advance the sciences and conduct innovative research. The pending funding restriction is critical and if it becomes clear to the foundation that the PI may come close to the $225K cut-off, they will be eliminated at the LOI stage. Dr. Beckman wanted to fund young scientists who may not be able to get other external funding at this early stage of their careers, and the Foundation upholds this. BYI is not NIH. If this is something that you apply to the NIH for, it is very likely that it will get kicked out at the LOI stage. Beckman is looking for cutting-edge, risky research that wouldn t be funded by a federal agency. There are no topical or disciplinary preferences for the Foundation in the life sciences or chemistry - they have purposely left the field very open to attract applications from PIs with a wide variety of research interests and expertise.

FORWARD THINKING: POSITIONING YOUR WORK FOR A BYI AWARD 1. Keep a file of reviewer comments that state or suggest that your work is too risky, blue sky, etc. 2. Subtly solicit such comments from program officers via email so you have a paper trail upon which you can draw in future submissions. 3. Allow yourself to dream big! Keep a journal. 4. Make a habit of following up on out-of-the-box ideas and generating concept papers. 5. Monitor federal agencies awards for projects aimed at the development of methods, instruments, or materials in your field of interest to get an idea of what Beckman will NOT fund. 6. Browse the abstracts of past Beckman winners at http://www.beckman-foundation.org/ programs/beckman-young-investigators-award-recipients to get an idea of what Beckman WILL fund.

CLEMSON S INTERNAL PROCESS A Limited Submission call for the Beckman Young Investigator Program will be announced by the VPR s Office in mid- to late- February 2018. Submissions will be due by mid-march 2018. We anticipate the BYI portal being open June-September 2018.

QUESTIONS? Primary Contacts: Amber Padgett day6@clemson.edu 864-656-2247 Sez Atamturktur sez@clemson.edu 864-656-3003