II BRAZILIAN INTRACRANIAL ANEURYSM COURSE: FROM GENESIS TO RUPTURE!

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SCIENTIFIC DIALOG II BRAZILIAN INTRACRANIAL ANEURYSM COURSE: FROM GENESIS TO RUPTURE! São Paulo, June, 10 th to 15 th, 2018 Hospital de Transplantes do Estado de São Paulo Euryclides de Jesus Zerbini (HTEJZ) Av. Brigadeiro Luis Antônio, 2651, São Paulo SP Support:

Under the scientific coordination of Dr. Sergio Tadeu Fernandes, MD, Division of Vascular Neurosurgery of the Hospital de Transplantes do Estado de São Paulo (HTEJZ) and with the presence of the international guest of honor - Prof. Juha Hernesniemi, MD, PhD, Helsinki Neurosurgery, University of Helsinki; and the presence of Latin-American renowned neurosurgeons Jorge Mura, IFAANS, FACS, Universidad de Chile, Instituto de Neurocirugía Asenjo, Chile and Pablo Rubino, MD, PhD High Complexity Hospital El Cruce, Buenos Aires, Argentina, we present the program: II Brazilian Intracranial Aneurysm Course: from genesis to rupture!. PREFACE The aim of this course is to demonstrate and discuss the different approaches and surgical techniques for the multidisciplinary treatment of several cerebral-vascular pathologies. The opening of the Course will be held on June 10 th, 2018 at 4:00 p.m. On this same date, at 6:00 pm, a welcome cocktail will be held at the Hospital de Transplantes do Estado de São Paulo (HTEJZ). The scientific and surgical activities will begin on June 11 th at 8:00 am, with lectures and live surgical procedures at HTEJZ. During the course will be performed daily, in addition to theoretical classes, microsurgical and endovascular procedures for the treatment of cerebral aneurysms, AVMs, AVFs and cavernomas. During this week of didactic and practical activities, participants will have the opportunity to discuss in detail different techniques for the treatment of the most varied cerebral-vascular pathologies, as well as the opportunity to bring their own cases for discussion with the masters. Accomplishment of the course: Aesculap Academy & Hospital de Transplantes do Estado de São Paulo (HTEJZ). The HTEJZ is a public hospital (exclusive service by the SUS Brazilian Public Health System) of reference in the treatment of brain-vascular pathologies diseases such as aneurysms and artery-venous malformations. The hospital counts on with a multi-professional team that performs microsurgical and endovascular procedures. With an excellent infrastructure, comprising 153 beds, nine operating rooms, one hemodynamic room and three Intensive Care Units - intermediate, adult and pediatric. About 900 employees work in the institution, among health professionals and the administrative area. The Neurosurgery Vascular Service of the HTEJZ carries out, per month, about 200 outpatient visits, 40 cerebral diagnostic angiographies and 10 therapeutic procedures, resulting in approximately 100 surgeries /year for cerebral aneurysms.

PROGRAM 10/06/2018 - SUNDAY 16:00 Welcome and registration 16:30 Opening Dr. Sergio Tadeu (Coordinator: Vascular Neurosurgery Division HTEJZ & Scientific Program) 17:00 Simple Fast Preserve Normal Anatomy: Basic Principles of Microsurgery: more than 40 years of experience! Dr. Juha Hernesniemi Finland 18:00 Opening Cocktail 11/06/2018 - MONDAY Lecture Session: bavm ss 08:00 Tricks in Cerebral AVM surgery: experience in more than 600 patients! Dr. Juha Hernesniemi Finland 09:00 Cases Discussion 09:30 Coffee Break Links to ORs and free circulation (Operating Room) 13:00 Lunch Break Lecture Session: bavm ss 14:00 Endovascular Management of bavm s 15:00 Coffee Break Links to Angio Suite and free circulation (Endovascular) 16:00 Briefing and discussion from audience 17:00 End of Activities 12/06/2018 - TUESDAY Lecture Session: Cavernous Malformation 08:00 Epidemiology, diagnosis & natural history Brigadeiro Hospital 08:00 Surgical Management Dr. Marco Zanini UNESP Botucatu

PROGRAM 09:00 Cases discussion & Post-op CTA s 09:30 Coffee Break / Links to ORs and free circulation (3 OR s) 13:00 Lunch Break Lecture Session: Bring your Case 14:00 Cases discussion 15:00 Coffee Break 15:00 Briefing and discussion from audience 16:00 End of Activities 13/06/2018 - WEDNESDAY Lecture Session: bavm ss 08:00 Epidemiology, diagnosis & natural history Brigadeiro Hospital 08:30 Defining Symptomatic bavm s and Classifications Dr. Paulo Porto HMASP 09:00 Microsurgical Management of bavm s Dr. Pablo Rubino Argentina 09:30 Cases discussion & Post-op CTA s Coffee Break Links to ORs and free circulation (OR s) 13:00 Lunch Break Lecture Session: bavfistulas 14:00 SpinalAVM - diagnosis and treatment! Hospital Brigadeiro 14:30 Dural AVF - endovascular management! Hospital Brigadeiro 15:00 Coffee Break Links to Angio Suite and free circulation 16:00 Briefing and discussion from audience 17:00 End of Activities

19:00 Hernesniemi s Book Release 20:00 Official Dinner 14/06/2018 - THURSDAY Lecture Session: Bypass Techniques in the era of EVT 08:00 Bypass Techniques: principles & indications Brigadeiro Hospital 08:30 Cerebral Revascularization of 3 rd generation Dr. Jorge Mura Chile 09:00 Cases discussion & Post-op CTA s 09:30 Coffee Break Links to ORs and free circulation (2 OR s) 13:00 Lunch Break Lecture Session: International Guest 14:00 Tricks in cerebral aneurysm surgery: more than 40 years of experience in more than 6,000 aneurysms! Dr. Juha Hernesniemi Finland 15:00 Coffee Break 15:30 Briefing and discussion from audience 16:00 End of Activities 15/06/2018 - FRIDAY Lecture Session: 08:00 Future of Cerebral Aneurysm treatment! Dr. Juha Hernesniemi Finland 09:00 Cases discussion & Post-op CTA s 09h30 Coffee Break Links to ORs and free circulation (2 OR s + Endovascular) 13:00 Briefing & Closing Ceremony

SPEAKERS SCIENTIFIC DIRECTOR: Sergio Tadeu Fernandes, MD FACULTY: Fabiano Ribeiro Rivau, MD Hugo L. Dória-Netto, MD Mario Luiz Marques Conti, MD, PhD Maurício Jory, MD Marcos Kendi Sekine, MD Pablo Resende Saa, MD Paulo Puglia Jr., MD, PhD Raphael Vicente Alves, MD, PhD Renan Luiz Lapate, MD NATIONAL GUESTS: Marco Zanini, MD, PhD Paulo Porto, MD, Msc GUEST OF HONOR: Juha Hernesniemi, MD, PhD Helsinki Neurosurgery. University of Helsinki, Finland INTERNATIONAL GUESTS: Jorge Mura, IFAANS, FACS Universidad de Chile. Instituto de Neurocirugía Asenjo, Chile Pablo Rubino, MD, PhD Hospital De Alta Complejidad El Cruce, Buenos Aires, Argentina

INFORMATION Event: II Brazilian Intracranial Aneurysm Course: from Genesis to rupture Venue: Hospital de Transplantes do Estado de São Paulo Euryclides de Jesus Zerbini (HTEJZ) Hospital Brigadeiro Adress: Av. Brigadeiro Luis Antônio, 2651, São Paulo Date: June, 10 th to 15 th, 2018 Participants: 60 Target: Neurosurgeons Support: SBN Sociedade Brasileira de Neurocirurgia e ZEISS 1. INSCRIPTION: R$ 4500,00 The fee includes full course program,, coffee-break, lunch, Dr. Juha s book launch cocktail, integration dinner (June 13 th ) and certificate. 2. INSTRUCTIONS FOR REGISTRATION: a. If you already have a registration on the site: www.aesculap-academia.com.br 1. Login (enter username and password) 2. Click on the event of your interest and then on Book 3. After the confirmation email you will receive the link for the inscription payment b. If you do not have an account on the site: www.aesculap-academia.com.br 1. Click on Registration at the top right 2. Fill in all fields, including the 2 options under Home Address 3. After filling it, you will receive an email to validate your registration on the site 4. After validation, enter your login and password 5. Click on the event of your interest and then on Book 6. After the confirmation email you will receive the link for the inscription payment Note: Payment can be made only by a credit card 3. CANCELLATION POLICY See cancellation policy on payment site CONTACTS Renata Almeida 21 2602 3175 renata.almeida@bbraun.com

The Aesculap Academy is one of the leading medical forums for everyone who is professionally, passionately and ambitiously committed to people s health. To those medical professionals we offer top quality knowledge transfer based on globally recognized quality criteria using innovative methods and technologies. DIALOG DEDICATED TO LIFE. The Aesculap Academy has its roots in the company B. Braun, which has been protecting and improving people s health for more than 175 years. With our courses, hands-on trainings and symposia we help to honor our parent company s promise of SHARING EXPERTISE. The courses at the Aesculap Academy offer participants who want to continue to learn in an inspiring environment knowledge transfer and teaching that are adapted to real life: lifelong learning, true-to-life training situations and realistic content for a better life for patients and medical staff. AESCULAP ACADEMIA Av. Eugênio Borges 1092, Arsenal 24751-000 São Gonçalo RJ Brasil www.aesculap-academia.com.br AESCULAP ACADEMIA a B. Braun company AA3650C-0118 - Maio/2018