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Centralized Chronic Medicine Dispensing and Distribution A Public/Private Partnership to Increase Access to HIV/Chronic Medication Phil Roberts Project Last Mile May 22, 2018 ICAP Grand Rounds Webinar

Agenda Introduction to Project Last Mile CCMDD in South Africa Current performance Business case Conclusion 2

Project Last Mile the early idea 3

Project Last Mile the early idea 4

Since the first pilot in 2010, Project Last Mile has activated programs in 8 out of 10 countries in Africa. GHANA (2011 2013) Pilot created a blueprint for improved uptime of cold chain equipment used for vaccines and introduced the use of market research & segmentation model to improve uptake and adherence for immunizations. NIGERIA (2016 present) Tapping into the Coca-Cola ecosystem to help improve uptime and management of vaccine cold chain equipment and save lives of children in Nigeria. LIBERIA (2017 present) Leveraging and adapting Coca-Cola best practices in demand planning, distribution optimization, network design, and organizational development. To help build a functioning medical supply chain for the Central Medical Stores. TANZANIA (2010 present) Building on six years of partnership to further strengthen distribution and management of medical supply chains in Tanzania. SIERRA LEONE (2017 recently started) Leveraging and adapting Coca-Cola best practices in distribution and organizational development to support supply chain strengthening. MOZAMBIQUE (2016 present) Applying Coca-Cola best practices in route-to-market and logistics to improve distribution of medicines and health products. SOUTH AFRICA (2016 present) Leveraging the Coca-Cola network and route-to-market experience to help revolutionize distribution of chronic medicines for over 2 million people. SWAZILAND (2016 present) Leveraging and adapting Coca-Cola best practices in strategic marketing to support increased demand for health services for HIV prevention, especially focused on young women. 5

Project Last Mile is an innovative Golden Triangle Partnership, bringing together public, private and civil society partners to improve the reach of critical medicines in Africa Launch Core Objectives Program Focus Examples Program Goal - Approached in 2009, Piloted 2010-2013, expansion announced June 25, 2014 - Improve availability of life-saving medicines and health services for people in the last mile of the health supply chain - Build health systems capacity in supply chain and marketing by sharing the expertise and network of the Coca-Cola system - Inspire broader private sector involvement through innovative cross-sector partnerships - Logistics/Distribution - Marketing - General Business Skills - Talent Management - Cold Chain Equipment Maintenance - To improve health systems management and supply chain efficiencies in 10 African countries by 2020 Just like any Coca-Cola product, life-saving medicines should be within reach of every person in Africa Progress - Programs activated in 8 out of 10 countries to date 6

Agenda Introduction to Project Last Mile CCMDD in South Africa Current performance Business case Conclusion 7

Background of South African Health Sector The changing epidemiological profile of South Africa has led to an over extension of public sector health care facilities. This has placed enormous strain on available resources and has contributed towards medicine shortages and challenges in the quality of care provided. 8

Background of South African Health Sector 9

Current service model: risks Poor patient experience, high costs for patients - Long travel times and distances, time off work etc. - Overcrowded facilities with long queues Overburdened facilities - Limited health care provider time with patients - Administrative burden for facility staff (processing patients, dispensing, patient record management etc.) Suboptimal stock management - Space limited for medicine storage, at facility and depot - Stock holding results in capital being locked Irrational prescribing & poor treatment adherence - Limited oversight regarding prescribing in line with standard treatment guidelines - Poor adherence due to barriers to access (above) 10

CCMDD Paradigm shift to differentiated service delivery Traditional Care Model CCMDD Care Model Source: NDoH Stable Chronic Patient Guidelines; PLM Team 11

CCMDD offers a more efficient medicine collection platform CCMDD improves patient access to medicine through central dispensing & distribution of medicines to patient convenient locations Source: NDoH Stable Chronic Patient Guidelines; PLM Team 12

CCMDD: A better service model for stable patients Vehicle for achieving Universal Health Coverage, 90-90-90 and Test & Treat Traditional service model = long queues and unproductive waiting times. CCMDD = no queues and short waiting times. Clinic staff get more time to focus on new patients. 13

CCMDD Patient benefits - Stable patients with chronic diseases can choose to enter the CCMDD programme - Once enrolled, patients collect predispensed medicine parcels from Pick-up-Points (PuPs) - These PuPs are either external (e.g. private sector service providers such as Clicks, Medirite etc.), or internal such as fast-track lanes, adherence clubs etc. - They return to their home health facility twice a year for repeat script and check up. More than 2 million Patients Enrolled (March 2018) 14

CCMDD Benefits 15

Agenda Introduction to Project Last Mile CCMDD in South Africa Current performance Business case Conclusion 16

CCMDD Registered Patients Growth 17

South African Patient Universe Significant opportunity for CCMDD growth exists given the gap to fill for TROA patients and SA stable chronic patient universe 40-50% of 12 million = 4.8-6.0 million 12.0 Total Patients, million 3.7 2.0 CCMDD TROA Stable Chronic Patient Universe Large opportunity for CCMDD growth: - In 2017 17% of stable chronic universe served on CCMDD & March 2021 Proposed Target is 43% - In 2017 50% of TROA patients are on CCMDD * 2017 Stable Chronic Patient Universe 12m calc: HIV 5.1m = [7.06m x 72% stable]; Hypertension 5.5m = [Prevalence (28.8%) x SA Pop. of >15yrs (38m) 11m x 50% Stable]; Diabetes 1.1m = [Prevalence (7.0%) x SA Population >20yrs (32m) x 50% Stable]. Epilepsy & Asthma <5% of total chronic patients, hence ignored to ensure chronic stable patient universe not over-estimated Source: Stats SA Aug 2017 Release P0302; HST SAHR 2017: NIDS 2015; HST weekly CCMDD tracker 19/01/2018. 18

CCMDD Patients by collection location There are a growing number of CCMDD patients collecting at external locations Percentage of Registered CCMDD Patients per collection point Source: HST weekly CCMDD tracker 19 January 2018; NDoH Guidance; PLM Team 19

Growth of external PuPs (2016 2018) 20

Agenda Introduction to Project Last Mile CCMDD in South Africa Current performance Business case Conclusion 21

Value generated from CCMDD benefits (2017/18) CCMDD delivers significant benefits for patients and NDoH Rand Billion, 2017 0.9m-1.2m additional patients treated in current facility infrastructure & staff (-0,1) 1.1 0,0 2.5 1.3 0.3 Patient Savings In 2017, CCMDD delivers: - 43% Patient cost reduction NDoH Facility Efficiency Gains* - 12-16% Increase in PHC facility capacity NDoH Medicine Supply Chain Costs* Adherence (NDoH**) - 48% decrease in NDoH cost to serve patients Socio Economics - 22% Increase in adherence Note: Indicative figures for 2mln CCMDD patients in 2017; Target CCMDD ratio by Patients by PuP Type. * Public Health Sector (NDoH) net value available to be repurposed: R1.5bn (includes R0.5bn Fees Paid to Service Providers & External PuPs: **Public Health Sector (NDoH) cost avoidance: R1.1bn Source: NDoH Actuals 2017; Available research; PLM Team Net Benefits 22

CCMDD Business Case Patient Improved Experience & Cost Savings NDoH - Increased Facility Capacity (Decongestion) - Facility Efficiency Gains - Increase in Medicine Supply Chain Cost - Increased Adherence Community Benefits Summary of Total Benefits 23

Business Case: Patient Savings Annual CCMDD Net Benefit to Patients & Public Health Sector for 2017/18 Rand Billion, 2017 0.9m-1.2m additional patients treated in current facility infrastructure & staff 0,0 2.5 1.1 (-0,1) 1.3 0.3 Patient Savings NDoH Facility Efficiency Gains* NDoH Medicine Supply Chain Costs* Adherence (NDoH**) Socio Economics Net Benefits Note: Indicative figures for 2mln CCMDD patients in 2017; Target CCMDD ratio by Patients by PuP Type. * Public Health Sector (NDoH) value available to be repurposed: R1.5bn **Public Health Sector (NDoH) cost avoidance: R1.1bn Source: NDoH Actuals 2017; Available research; PLM Team 24

Patient benefit methodology Evaluate costs that patients incur: - On CCMDD program - Not on CCMDD program Type of patient costs to evaluate: - Transport costs - Loss of income - Substitute labour Source: PLM Team; NDoH Guidance 25

Business Case: Patient Savings Chronic Stable Patient Inputs 2017 Annual Patient Cost to Visit a Facility 2017, Rand per year per patient No. of PHC facility visits per patient per year - Non-CCMDD, SFLA, AC: 6 - External PuP: 2 Patient cost per visit to PHC facility - R54.94* 2 Million CCMDD patients 60% at External PuP = 1,2 Million Patients 1,2M x R54,94 x 4 visits saved R0,26bn saved by Patients 110 Non-CCMDD, SFLA, AC Cost External PuP Cost 330-67% 67% reduction in a patient cost to collect medicine at external PuPs per year Patient Savings R0.26bn in 2017 *2005 & 2007 costs inflated to 2017 based on CPI; Average: Urban, Prei-Urban, Rural used as proxy for all patients Source: Rosen, Kethlhapie & De Silva 2005; Rosen, Kethlhapie Sanne & De Silva 2007; PLM Team; Stats SA Aug 2017 26

Replicable sustainable solution 27

Agenda Introduction to Project Last Mile CCMDD in South Africa Current performance Business case Conclusion 28

Recommendation Accelerate CCMDD roll-out due to: - Massive positive impact - Support to achieve 90-90-90 targets in 2020 Encourage existing CCMDD patients collecting at Facilities to shift to External PuP & Adherence Clubs Ensure a CCMDD District Support Partner is in place in every District to assist with implementation Source: NDoH Guidance; PLM team 29

Next steps Develop communication plan to share positive impact CCMDD has for patients & NDoH - DoH various levels & all stakeholders Proactively engage & align on: - CCMDD Benefits - Targets: including contribution to other programs: e.g. 90-90-90 - Budgeting & re-allocation of funds to enable CCMDD roll out - Overlap with other programs (e.g., CCMDD patient data for 90-90-90) Develop CCMDD implementation plan with right structures in place at National, Provincial & District level - Functional - Top management support Create list (check box) of support / input required from various audiences to set up implementation for success 30

Thank You