SAVING LIVES AND CREATING IMPACT. EU investment in poverty-related neglected diseases

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SAVING LIVES AND CREATING IMPACT EU investment in poverty-related neglected diseases

1 What has the EU invested in PRND R&D? 2 How have developing countries benefitted? 3 What is the return on investment for Europe? EU Investment in PRND R&D Health and prosperity in developing countries = + Growth and competitiveness in the EU Levels of funding Nature of funding Health impact Economic impact Research capacity Jobs created Leveraged investment Scientific excellence Industrial competitiveness Health in the EU Integration

1 What has the EU invested in PRND R&D? The EU invests 341 million a year in PRND R&D 15% OF ALL FUNDING FOR PRND R&D

1 What has the EU invested in PRND R&D? Top Funders 87m 2 nd UK 93m 53m 3 rd France 1 st EC

1 What has the EU invested in PRND R&D? Sweden 0.0054% Finland 0.0004% Member State Funding by GDP Ireland 0.0047% UK 0.0049% Denmark 0.0042% Netherlands 0.0035% Germany 0.0007% USA 0.01% Brazil 0.0017% India 0.0017% Belgium 0.0016% France 0.0013% Luxembourg 0.0032% EU 0.0024% Italy 0.0002% Spain 0.0013%

2 How have developing countries benefitted? Pharmaceutical Innovation MDG 1 Eradicate Extreme Poverty and Hunger MDG 2 Achieve Universal Primary Education MDG 3 Promote Gender Equality and Empower Women MDG 4 Reduce Child Mortality MDG 5 Improve Maternal Health MDG 6 Combat HIV/AIDS, Malaria and other diseases MDG 7 Ensure Environmental Sustainability MDG 8 A Global Partnership for Development

2 How have developing countries benefitted? EU investment has contributed to the creation of 43 new PRND products

2 How have developing countries benefitted? MALARIA INFECTS 216+ MILLION PEOPLE KILLS AROUND 655,000 PEOPLE KEY PHARMACEUTICAL INNOVATIONS 1. COARTEM 2. ASAQ 3. EUARTESIM Image Credit: Anne Heslop Photography

2 How have developing countries benefitted? 359 products in development 43% involving European developers FOR VACCINES ALONE, THERE ARE PROMISING CANDIDATES FOR BURULI ULCER, TUBERCULOSIS AND SCHISTOSOMIASIS

2 How have developing countries benefitted? Key Developing Country Research Institutions in Africa & Asia Medical Research Council, Gambia International Centre for Diarrhoeal Disease Research, Bangladesh Ifakara Health Institute, Tanzania Medical Research Unit Albert Schweitzer Hospital, Gabon Manhiça Health Research Centre, Mozambique

3 What is the return on investment for Europe? EU investment created more than 13,000 jobs

3 What is the return on investment for Europe? Two-thirds of Europe s PRND R&D funding is invested back into Europe

3 What is the return on investment for Europe? 1 2.05 Industry 0.53 Philanthropy 0.45 Other gov ts 0.07

3 What is the return on investment for Europe? Liverpool School of Tropical Medicine Statens Serum Institute Karolinska Institute London School of Hygiene & Tropical Medicine Bernhard Nocht Institute for Tropical Medicine Top European PRND Research Institutes Royal Tropical Institute Heidelberg University Institute of Tropical Medicine University of Tübingen Institut Pasteur Barcelona Centre for International Health Research Swiss Tropical Institue of Public Health

3 What is the return on investment for Europe? 6x industry The European pharmaceutical industry invested six times more than the U.S. relative to annual revenues

Opportunity: Horizon 2020 Increased PRND R&D investment under Horizon 2020 will benefit both developing countries and Europe

Opportunity: Horizon 2020 EU Investment in PRND R&D = Building Capacity in Developing Countries Quality Research + + Collaboration & partnerships + + Integrating Industry = Health and prosperity in developing countries + Growth and competitiveness in the EU

Recommendations Recommendations 1 Increase investments in PRND R&D including an increased commitment from the EC under Horizon 2020

Recommendations 2 Retain and foster the distinctive benefits of its approach to funding PRND R&D

Recommendations 3 Improve specific aspects of its investment in PRND R&D, to ensure greater efficiency, impact and value

Thank you