How Safe Are Your Patients? Creating a Meaningful & Actionable Medication Safety Dashboard By: Helga Brake, PharmD, CPHQ Patient Safety Leader Northwestern Memorial Hospital No Conflicts of Interest to Disclose Northwestern Memorial HealthCare 873-bed Nationally Recognized Academic Medical Center Tertiary care center providing a full range of services for adults and neonates Nationally Ranked for Quality Feinberg and Galter Pavilions Prentice Women s Hospital 1
How Do You Know Your Patients Are Safe? Adverse drug events result in more than 77, injuries and deaths each year and cost up to $5.6 million per hospital, depending on size 1 Hospitalized patients are subjected to an average of more than one medication error each day 2 Delivery of a single dose of a medication is the result of a process involving 3-4 steps. Using process steps as the denominator, medication error rate in hospitals may be as low as 1 in 1, to 1 in 1, 3 1 Reducing and preventing adverse drug events to decrease hospital costs. Agency for Healthcare Research Quality. Research in Action, Issue 1. Available at: http://www.ahrq.gov/qual/aderia/aderia.htm. Accessed on March 1, 21. 2 Aspden P, Wolcott J, Bootman JL, Cronenwett LR, editors. Preventing medication errors: crossing the quality chasm: committee on identifying and preventing medication errors. Washington, DC: National Academies Press; 27. 3 Cohen MR, editor. Medication errors. 2 nd ed. Washington, DC: American Pharmacists Association; 27 Poll Question How many of you are responsible for or have input into your organization s medication safety dashboard? A. Yes, I am responsible and/or have input into the dashboard B. No direct responsibility or input C. Organization does not have a medication safety dashboard D. Not applicable 2
Criteria For Well-Designed Dashboard Measures Strategict High-risk, high-volume, highly-vulnerable, and problem prone areas Regulatory issues Support improvement activities Criteria For Well-Designed Dashboard Measures Technical Meaningful and Accurate Available data from various sources Ability to identify opportunities Transformable 3
Additional Considerations Who should see the dashboard? How frequently should the dashboard be updated? What actions should be taken in response to the information presented in the dashboard? NMH Med Safety Dashboard Examples Reported Medication Incidents Errors involving severe patient harm or death are reported to the Clinical Care Evaluation Committee for follow-up % of All Reported Medication Errors 1% 9% 8% 7% 6% 5% 4% 3% 2% 1% % 227 131 Reported Medication Errors by Severity of Harm 242 46 241 62 291 64 3 2 4 3 Q2 FY8 Q3 FY8 Q4 FY8 Q1 FY9 Q2 FY9 Q3 FY9 Q4 FY9 Q1 FY1 Time Period Error, No Harm Error, Temporary Harm Error, Severe Harm or Death 291 44 264 79 252 38 275 54 Severity of Harm (NCC MERP Index Categories) Error, No Harm (B-D): An error occurred that: 1. (B) did not reach the patient, or 2. (C) reached the patient but did not cause patient harm, or 3. (D) reached the patient and required monitoring to confirm no harm and/or required intervention to preclude harm Error, Temporary Harm (E, F): An error occurred that (E) contributed to or resulted in temporary patient harm and required intervention or (F) required initial or prolonged hospitalization Error, Severe Harm or Death (G-I) An error occurred that (G) contributed to or resulted in permanent patient harm, or (H) required life-sustaining intervention, or (I) death All Reported Medication Errors, Categories B - I Q2 FY8 Q3 FY8 Q4 FY8 Q1 FY9 Q2 FY9 Q3 FY9 Q4 FY9 Q1 FY1 361 29 37 355 338 344 29 329 Note: Numbers above bars represent the number of reported medication incidents. Data Source: NETS voluntarily-reported database 4
Medication Incidents By Type Of the 242 reported E I medication incidents that caused patient harm during the 29 fiscal year, those due to allergic reactions and extravasations were most frequent. allergic reaction extravasation/infiltration other (describe below) wrong dose/strength adverse reaction wrong medication administration of reversal unordered medication extra dose/duplication omission wrong rate wrong time wrong route wrong administration technique wrong frequency wrong dosage form Frequency of Reported Medication Incident Types FY9 12 11 8 7 6 5 4 3 2 2 1 1 2 17 % 5% 1% 15% 2% 25% 3% 35% 4% Percentage of Reported Medication Incidents with Harm Score Between E - I 52 9 Note: Numbers to the right of the bars represent the number of reported medication incidents by category Data Source: NETS voluntarily-reported database NPSG: Medication Reconciliation Compliance Numerator: Patients with Med Rec Completed at both Admission and Discharge Denominator: All NMH inpatients discharged during the specified time period Med Rec Completed on Admission : Medication Reconciliation form completed by physician or nurse or pharmacist Med Rec Completed on Discharge : Documented completion of Nursing Discharge Note Patients are excluded if: Expired, Left AMA, Neonate, Newborn Data Source: PowerChart, EDW report 5
Med Rec Drilldown Compliance By Nursing Unit Numerator: Patients with Med Rec Completed at both Admission and Discharge Denominator: All NMH inpatients discharged during the specified time period Data Source: PowerChart, EDW report Anticoagulation: DVT and PE Events Incidents Per 1 Eligible Patients 25. 2. 15. 1. 5.. DVT/PE Prophylaxis DMAIC implementation DVT and PE Events Aug-9 Jul-9 Jun-9 May-9 Apr-9 Mar-9 Feb-9 Jan-9 Dec-8 Nov-8 Oct-8 Sep-8 Switch to Fragmin Discharge Month Deep Vein Thrombosis Pulmonary Embolism Data Source: EPSI financial billing data, chart review 6
DVT/PE Events By Type 8 7 6 5 4 3 2 1 DVT/PE Prophylaxis DMAIC implementation NMH DVT/PE Events Switch to Fragmin Sep-8 Oct-8 No v- 8 De c- 8 Jan- 9 Feb-9 Mar-9 Apr-9 May-9 Jun- 9 Jul-9 Aug-9 LE DVT PE UE DVT Lower Extremity (LE) DVT: Pts with Diagnosis Code of 451.11, 451.19, 451.2, 451.81, 451.9, 453.4, 453.41, 453.42; not POA Pulmonary Embolism (PE) Events: Patients with a diagnosis code of 415.11 or 415.19; not Present on Admission (POA) Upper Extremity (UE) DVT Events: Numerator: Patients with a Diagnosis Code of 453.8 or 453.9; not POA Denominator: Patients who did not have a DVT or PE diagnosis code; Exclusion: OB, Psych, and Pediatric patients Data Source: EPSI financial billing data Anticoagulation: Bleed Events Anticoagulants (warfarin and heparin) causing adverse effects in therapeutic use DVT/PE Prophylaxis DMAIC implementation Bleed Events Switch to Fragmin Events Per 1 Eligible Patients Bleed 7. 6. 5. 4. 3. 2. 1.. Aug-9 Jul-9 Jun-9 May-9 Apr-9 Mar-9 Feb-9 Jan-9 Dec-8 Nov-8 Oct-8 Sep-8 16 15 12 1 8 7 8 13 14 12 12 7 Discharge Month Numerator: Patients with a Diagnosis Code of E934.2 that was not Present on Admission Denominator: Patients who did not have a Bleed Diagnosis code Present on Admission Note: Numbers above bars represent the number of bleed events. Data Source: EPSI financial billing data; chart review 7
Devices: Smart Intravenous Infusion Pumps Guardrails limits were used in over 9% of all infusions in FY9 Infusions Delivered Using Guardrails Dosing Safety Software vered by General Infusion Pump Infusions Deliv 1% 9% 8% 7% 6% 5% 4% 3% 2% 1% % Sep-8 Oct-8 Nov-8 Dec-8 Jan-9 Feb-9 Mar-9 Apr-9 May-9 Jun-9 Jul-9 Aug-9 % Infusions Usings Guardrails Data Source: Alaris pump Guardrails Continuous Quality Improvement pump data Infusions by Care Area 14% of Med/Surg and 13% of Heme/Onc infusions were administered to patients outside of the safety of Guardrails limits in FY9. Infusions Using Guardrails By Care Area General Pump Infusions 1% 9% 8% 7% 6% 5% 4% 3% 2% 1% % Med/Surg 23% 11% 45% 2% 3% 8% 8% Hematology/Oncology Critical Care/ED Neonate >=2.1 21 kg Neonate <= 2 kg Anesthesia Labor and Delivery Infusions Using Guardrails Infusions NOT Using Guardrails Note: Mid-column percentage represents the percent of total infusions for the specific care area Time Period: September 28 August 29 Data Source: Guardrails Alaris pump CQI data 8
Top Drugs Triggering Alerts Fentanyl and dobutamine infusion programming generated the most Guardrail limit alerts during FY9. Number of Alerts 7 6549 1% 6 5 4 3 2 1 52% 53% 55% 57% 58% 6% 61% 62% 63% 64% 65% 66% 67% 7% 6% 5% 47% 45% 5% 43% 2829 4% 37% 2413 34% 4% 2249 31% 27% 1864 23% 174 1735 3% 1483 18% 1359 1263 117 1157 13% 137 978 2% 932 82 81 685 646 621 556 59 476 462 418 1% 9% 8% Cumulative Frequency of Alerts fentanyl DOBUTamine oxytcin INTRApartum.Trisodium Citrate cyclophosphamide lorazepam propofol DOXOrubicin potassium chloride calcium gluconate hydromorphone heparin cytarabine Calcium Chlor 1g/25 bumetanide insulin cisatracurium VANCOmycin meropenem CISplatin 3% sodium chloride phenytoin mycophenolate PPN-Peripheral TPN vasopressin % Drug Time Period: Sep 28 Aug 29 Data Source: Guardrails Alaris pump CQI data High Alert Medication: Fentanyl The majority of fentanyl alerts occur in the critical care areas, are overridden, and involve doses just outside of the set limits. 25 2 May represent limits that are too restrictive 268 2314 Number of Alerts 6 5 4 3 2 1 5178 494 299 33 Critical Care/ED Hematology/Oncology Med/Surg Anesthesia of Frequency Count o 15 1 5 2 155 319 196 Reprogram Limit Alert Resolution Type by Profile 32 18 -.499.5 -.999 1-1.499 1.5-1.999 2-2.499 2.5-4.999 5-9.999 1 1-99.999 1 1+ Times the Limit Count Override Limit Alert Primarily represents decimal point errors. GOOD CATCHES! Time Period: Sep 28 Aug 29 Data Source: Guardrails Alaris pump CQI data 9
Poll Question How many of you work for an organization that t includes a medication error rate based on reported incidents on its dashboard A. Yes B. No C. Not applicable And Finally..What DOESN T Belong on Your Dashboard Medication error rates based on reported incidents least effective and least reliable determinant of the true error rate Provider-specific cases Nice to Know information Unavoidable events Unreliable data 1
Helga Brake, PharmD, CPHQ Patient Safety Leader Northwestern Memorial Hospital Chicago IL 6611 312.926.234 hbrake@nmh.org If you want to learn more about Northwestern Memorial Hospital, please visit our website at http://www.nmh.org Privileged and confidential under the IL Medical Studies Act 11
ICHP Spring Meeting 21 Brake Medication Safety Pearls: Medication Safety Dashboard 121--1-14-L5-P & T Post-test Questions 1. Which of the following items do not belong on a medication safety dashboard? A. Medication processes that are high-risk B Medication processes that are problem prone C. Avoidable medication-related events D. Unavoidable medication-related events E. Medication related regulatory issues 2. Medication error rates based on reported incidents is the most effective and reliable determinant of a true error rate. True or False