The Davies Award Is: The HIMSS Nicholas E. Davies Award of Excellence. Awarding IT. Improving Healthcare.

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The Davies Award Is: Since 1994, the Nicholas E. Davies Award of Excellence is HIMSS highest global recognition of hospitals, ambulatory practices and clinics, community health organizations, and public health organizations that utilize electronic health records and information technology to improve clinical and financial outcomes. The Davies Award is international and open to all healthcare delivery systems that meet the prerequisites. The Davies Award is vendor-agnostic. The HIMSS Nicholas E. Davies Award of Excellence Awarding IT. Improving Healthcare.

- Speaker Bio(s) Taylor Hargrave, BSN, RN, CIC, Infection Prevention Supervisor Amanda Logue, M.D., Chief Medical Information Officer The HIMSS Nicholas E. Davies Award of Excellence Awarding IT. Improving Healthcare.

Sepsis Lafayette General Health 2017 Nicholas E. Davies Enterprise Award of Excellence Taylor Hargrave, BSN, RN, CIC, Infection Prevention Supervisor Amanda Logue, M.D., Chief Medical Information Officer

Lafayette General Health Who we are 7 Inpatient facilities (incl. Academic) 43 Ambulatory sites: 18 specialties 1 Ambulatory surgery center 4,043 FTEs 68 Employed Physicians 1,700 Non-Employed Medical Staff Acute HIMSS Level 6 (LGMC & UHC) Our patients 29,000 Admissions 180,000 ED visits 23,000 Surgical cases 335,000 Outpatient visits Top Service lines: Cardiology Neurology Orthopedics Fiscal Year 2016 (Sept. 2015 - Sept.2016)

Information Systems automation journey 2003 2012 2014 2016 CPOE, Documentation, ED, Pharmacy, Revenue Cycle System re-install, Surgery, Cerner Patient Accounting, Quality Alignment Remote Hosting Women s Health, Care Management, Registries, CommonWell, EPCS, HealthyLink clinics Hospitals acquired: Radiology, PACS, Laboratory Ambulatory ASP, Oncology Integrated Ambulatory, Sepsis, PSI-15 process, New CDI software EDW, HealthyLink hospital system, Palm Scanning, Patient Observer 2006 2013 2015 2017

Local Problem

33.13% of overall mortality rates attributed to Sepsis Previous workflow: Reviewed current symptoms vs. early detection Identification only considered Temperature, HR, and Systolic BP (Rules of 100s) When patient's vital signs met criteria a sheet was automatically printed on the ICU printer The Rapid Response Team nurse went patient's unit and spoke with the primary nurse, assisted with patient assessment if appropriate Contributing factors: Unemployment rates increasing, patients losing health benefits 1 Patients tend to wait to seek treatment, sicker when in hospital 1 Reference the appendix for Lafayette vs National unemployment rates

Sepsis Mortality Rate and Incident Count Diagnosis group* Mortality Rate Monthly Average LGMC Mortality 2.13% Overall Sepsis 16.54% Sepsis 7.28% Severe Sepsis 18.92% Septic Shock 33.33% % of mortality attributed to sepsis 33.13% Time period: Nov. 2014 Nov. 2015 *ICD-10 diagnoses included in each category listed in Appendix Data Source: LGMC Cerner EHR database

Sepsis Incident Count by Diagnosis Group Diagnosis group* Incident Count Monthly Average Overall Sepsis 77 Sepsis 38.08 Severe Sepsis 9.83 Septic Shock 23.67 Time period: Nov. 2014 Nov. 2015 Overall Sepsis includes Sepsis, Severe Sepsis, and Septic Shock cases Data Source: LGMC Cerner EHR database

Sepsis Incident Count by DRG DRG Monthly Average 870 1 Sickest 3.36 871 2 Sicker 26 872 3 Sick 7.73 Time period: June 2014 May 2015 1 SEPTICEMIA OR SEVERE SEPSIS W MV 96+ HOURS 2 SEPTICEMIA OR SEVERE SEPSIS W/O MV 96+ HOURS W MCC 3 SEPTICEMIA OR SEVERE SEPSIS W/O MV 96+ HOURS W/O MCC Data Source: LGMC Cerner EHR database

Sepsis Length of Stay Diagnosis LOS: Days Monthly Average Hospital Wide 4.5 Overall Sepsis 9.35 Sepsis 8.61 Severe Sepsis 7.25 Septic Shock 12.21 Time period: Nov. 2014 Nov. 2015 Data Source: LGMC Cerner EHR database

Sepsis Core Measure 1 LGMC prego live compliance 2.44% Time period: Oct. 2015 Feb. 2016 1 Measure Set: Sepsis Set Measure ID #: SEP-1 Performance Measure Name: Early Management Bundle, Severe Sepsis/Septic Shock Description: This measure focuses on adults 18 years and older with a diagnosis of severe sepsis or septic shock. Consistent with Surviving Sepsis Campaign guidelines, it assesses measurement of lactate, obtaining blood cultures, administering broad spectrum antibiotics, fluid resuscitation, vasopressor administration, reassessment of volume status and tissue perfusion, and repeat lactate measurement. As reflected in the data elements and their definitions, the first three interventions should occur within 3 hours of presentation of severe sepsis, while the remaining interventions are expected to occur within 6 hours of presentation of septic shock. Rationale: The evidence cited for all components of this measure is directly related to decreases in organ failure, overall reductions in hospital mortality, length of stay, and costs of care. The Joint Commission. (2016) Specifications Manual for National Hospital Inpatient Quality Measures v.5.2a (applicable 1/1/2017-12/31/2017). https://www.jointcommission.org/specifications_manual_for_national_hospital_inpatient_quality_measures.aspx Data Source: LGMC Cerner equalitycheck

LGMC baseline cost per case by DRG DRG Cost per DRG 870 1 Sickest $27,669.24 871 2 Sicker $11,902.18 872 3 Sick $7,434.45 Time period: Mar. 2015 Feb. 2016 1 SEPTICEMIA OR SEVERE SEPSIS W MV 96+ HOURS 2 SEPTICEMIA OR SEVERE SEPSIS W/O MV 96+ HOURS W MCC 3 SEPTICEMIA OR SEVERE SEPSIS W/O MV 96+ HOURS W/O MCC Data Source: Premier Quality Advisor

Design Implementation Governance

Governance Governance: Executive Sponsor: CMIO Clinical Transformation Committee Medical Executive Committee Project team: Quality department IT analysts Nursing subject matter experts (ICU, Med-Surg, RRT, ED) Clinical pharmacists Cerner Quality Reporting Goals/Anticipated outcome: Increase early detection and prevention of Sepsis Decrease mortality associated with Sepsis

Design and Build Design & build Training plan Support plan Adoption Project Timeline: 14 months Algorithm monitoring and modification: Alert initially built in silent mode Project team audited and validated alert population and frequency Excluded: CV surgery for the initial 24 hours post-op Active laboring population for 24 hours Comfort measures only patients for duration of stay NICU, Nursery, Pediatrics

Design and Build, cont. Design & build Training plan Support plan Adoption Decisions: Who to alert Frequency of alert Every patient will only alert once Q24 hours. Alerts are suppressed for extended time (72 hours) if a sepsis order set is active or if a sepsis diagnosis is in place When to call physician Additional FTE added to Rapid Response Team (LGMC) Repeat lactate orders: If any lactate result is > 2.0, then an automatic timed lactate is ordered for 5 hours after the original lab was ordered

Review of alerts prior to go-live May 2015 Total Alerts SIRS and Sepsis N = 172 alerts 47% Infectious Etiology* Non-infectious Etiology** 53% *Infectious Etiology = Infection documented or developing at the time of alert **Non-Infectious Etiology = No infection documented or developing at time of alert

Review of alerts prior to go-live SIRS or Sepsis Alerts by Infectious Etiology May 2015 Count of Alerts 35 30 25 20 15 10 30 26.1% 28 50.4% 26 73.0% 90.4% 20 97.4% 8 99.1% 100.0% 120% 100% 80% 60% 40% Percent of Total 5 0 2 1 20% 0% Infectious Etiology Count of Alerts Cumulative %

Review of alerts prior to go-live Count of Alerts 18 16 14 12 10 8 6 4 2 0 16 17.8% 15 34.4% 10 45.6% SIRS or Sepsis Alerts by Non-Infectious Etiology May 2015 8 54.4% 75.6% 68.9% 62.2% 7 6 6 81.1% 86.7% 5 5 5 92.2% 96.7% 97.8% 98.9% 100.0% 4 1 1 1 120% 100% 80% 60% 40% 20% 0% Percent of Total Non-Infectious Etiology Count of Alerts Cumulative %

Training Design & build Training plan Support plan Adoption 1 month prior to go-live: all nurses assigned module via Elsivier training on alert workflow Infection Prevention (IP) attended hospitalist meetings to explain the core measure Quick reference laminated pocket cards were provided to physicians Education provided to physician residents via LSU education platform IP attended Women's Services staff meetings to discuss core measures; information included in department newsletter See Sepsis Appendix for sample training materials

Support and Measure Infection Prevention quarterly review of all Sepsis patients Synopsis of all core measure passes and misses sent to those involved in care of patient at the time of event Thank you card sent to physicians responsible for passes Opportunity letter sent to physicians responsible for misses Synopsis of passes and misses sent to each leader monthly

Opportunity and Thank You letters

How Health IT was Utilized

How Health IT was Utilized Cerner St. John Sepsis Agent: Gathers and combines patient information and vital signs from EHR Fires alert in EHR when signs for SIRS or organ dysfunction are detected Electronic alerts based on algorithm Orders/tasks to drive action Evidence-based electronic order sets Sepsis quality measure compliant Improve antibiotic use identification Core measure reporting

St. John Sepsis Agent Algorithm

Sepsis Inpatient Workflow Green boxes = Health IT utilization

Sepsis ED Workflow Green boxes = Health IT utilization

SIRS Alert At least 3 SIRS criteria met Date and Time appear prior to the clinical event in the alert Includes a link to the patient s chart in the message Screenshot from Cerner EHR

Sepsis Alert At least 2 SIRS criteria and 1 organ dysfunction criteria Alert for the patient who meets criteria for the Sepsis Security Rule should display as shown Date and Time appear prior to the clinical event in the alert Includes a link to the patient s chart in the message Screenshot from Cerner EHR

Rapid Response Team Beeper Every Sepsis Alert sent to Rapid Response Team Beeper

Alert order placed on patient s chart with nursing task Patient Order Profile Screenshot from Cerner EHR Nurse Task List

ICU Decision Tree Used to determine if physician notification needed

Provider Notification Form If deemed clinically necessary, nurse will contact provider and document communication in EHR Screenshot from Cerner EHR

ED Tracking Board icon Screenshot from Cerner EHR

Sepsis Order Sets Screenshot from Cerner EHR

Key Orders in Sepsis Order Sets Sepsis Quality Measure Order Sepsis Severity Identification Order Screenshot from Cerner EHR

Sepsis Severity Identification Order Completed by physician to identify the type of sepsis being treated and suspected source of infection Drives electronic documentation for the Sepsis core measure and helps with the establishment of time zero Screenshot from Cerner EHR

Early Warning Alerts Flowsheet One-stop-shop for discrete sepsis information Screenshot from Cerner EHR

Value Derived

Decreased Sepsis Mortality Rate 35% 30% LGMC Mortality Rate Data 33.33% 28.77% 25% 20% 15% 10% 5% 2.13% 1.89% 16.54% 12.69% 7.28% 6.29% 18.92% 9.41% 0% Hospital Mortality Rate Overall Sepsis Mortality Rate Sepsis Mortality Rate Severe Sepsis Mortality Rate Septic Shock Mortality Rate Baseline (Nov. 2014 - Nov. 2015) Outcome (Mar. 2016 - Feb. 2017) Data Source: LGMC Cerner EHR database

Decreased Sepsis Mortality Rate Diagnosis Group Monthly Average (Nov. 2014 Nov. 2015) Monthly Average (Mar. 2016 Feb. 2017) Percent change in Mortality Rate Hospital Mortality 2.13% 1.89% -11.17% Overall Sepsis 16.54% 12.69% -23.26% Sepsis 7.28% 6.29% -13.66% Severe Sepsis 18.92% 9.41% -50.26% Septic Shock 33.33% 28.77% -13.68% % of mortality attributed to sepsis 33.13% 31.2% -5.83% Data Source: LGMC Cerner EHR database

Improved Sepsis Core Measure Compliance by 949.48% LGMC Sepsis Core Measure Compliance 30% 25% 20% 15% 10% 5% 0% 2.46% Pre-go live compliance (Oct. 2015 - Feb. 2016) 25.86% Post-go live compliance (March. 2016 - Feb. 2017) Data Source: LGMC Cerner equalitycheck

Increased Incident Count/Coding 60 Change in Incident Coding by Diagnosis Group 50 50.08 40 38.08 30 23.67 22.83 20 10 5.42 12.25 9.83 12.42 0 SIRS Sepsis Severe Sepsis Septic Shock Baseline Monthly Average (Nov. 2014 - Nov. 2015) Outcome Monthly Average (Mar. 2016 - Feb. 2017) Data Source: LGMC Cerner EHR database

Increased Incident Count/Coding 40 35 30 25 20 15 10 5 0 Change in Incident Coding by DRG 35.33 26 13.83 7.73 3.36 2.42 870 Sickest 871 Sicker 872 Sick 1 SEPTICEMIA OR SEVERE SEPSIS W MV 96+ HOURS 2 SEPTICEMIA OR SEVERE SEPSIS W/O MV 96+ HOURS W MCC 3 SEPTICEMIA OR SEVERE SEPSIS W/O MV 96+ HOURS W/O MCC Baseline Monthly Average (Jun. 2014 May 2015) Outcome Monthly Average (Mar. 2016 Feb. 2017) Data Source: LGMC Cerner EHR database

Stable Sepsis Length of Stay Change in LOS by Diagnosis Group Days 14 12 10 8 6 4 4.5 4.65 9.35 9.48 8.61 8.48 7.25 7.58 12.21 13 2 0 Hospital Wide Overall Sepsis Sepsis Severe Sepsis Septic Shock LOS days Monthly Average (Nov. 2014 Nov. 2015) LOS days Monthly Average (Mar. 2016 Feb. 2017) Data Source: LGMC Cerner EHR database

Decreased Cost Per Case DRG Cost per DRG Baseline (Mar. 2015 Feb. 2016) Cost per DRG Outcome (Mar. 2016-Feb. 2017) Number of Cases (Mar. 2016 Feb. 2017) Cost Savings (Mar. 2016 Feb. 2017) 870 Sickest $27,669.24 $27,633.68 29 $1,031.24 871 Sicker $11,902.18 $11,413.57 424 $207,170.64 872 Sick $7,434.45 $6,618.30 116 $135,480.90 Total cost savings $343,682.78 How decreased cost: Diagnosing sooner impacts progression of disease Coded more patients with sepsis diagnosis codes Decreased mortality and improved outcomes Improved efficiencies to care for patient lowered cost to provider, patient, and payer Data Source: Premier Quality Advisor

39.84 Lives Impacted/Saved Overall Sepsis Lives Impacted/Saved Analysis Month Sepsis Mortality Total Sepsis Sepsis Mortality Count Encounters Rate Baseline 12.54 75.15 16.54% -- Mar-16 8 74 10.81% 4.24 Apr-16 9 96 9.38% 6.87 May-16 12 77 15.58% 0.74 Jun-16 8 84 9.52% 5.90 Jul-16 13 85 15.29% 1.06 Aug-16 11 74 14.86% 1.24 Sep-16 9 87 10.34% 5.39 Oct-16 10 75 13.33% 2.41 Nov-16 14 97 14.43% 2.04 Dec-16 7 85 8.24% 7.06 Jan-17 13 96 13.54% 2.88 Feb-17 17 100 17.00% 0.00 TOTAL 39.84 Monthly Average Lives Impacted/Saved* 3.32 *Lives impacted/saved calculated by multiplying the change in mortality rate from baseline and the number of sepsis encounters per month

Future considerations ED physician note often started without a sepsis diagnosis When sepsis enters the differential, an addendum is made and treatment orders are entered If the addendum does not have a time stamp, then time zero becomes when the note was first opened Create nursing documentation identifying sepsis onset that physician can pull into note Evaluate SOFA criteria vs. old CMS SIRS criteria Will the CMS specs change as the Surviving Sepsis campaign adopts new criteria? SIRS and sepsis ED icons are difficult to differentiate for color blind employees Include CMO with physician opportunity letters for misses Work with Intensivists to stay up to date on sepsis recommendations

Thank you

Appendix

LGH Patient Population 12 Lafayette Metro vs. U.S. National Average Unemployment Rate 10 Percent Unemployment 8 6 4 2 0 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Lafayette Metro National Linear (Lafayette Metro) U.S. Department of Labor, Bureau of Labor Statistics. (2017). Retrieved from https://www.bls.gov/data/#unemployment

Sepsis Diagnosis Group Data Criteria Encounter Types Hospice Inpatient LBHU Inpatient LTAC Long Term Care Rehab Swingbed SIRS Diagnosis List (ICD-10) R65.10 R65.11 Sepsis Diagnosis List (ICD-10) 771.81 995.91 A02.1 A22.7 A26.7 A32.7 A40.0 A40.1 A40.3 A40.8 A40.90 A40.9 A41.01 A41.02 A41.1 A41.2 A41.20 A41.3 A41.4 A41.50 A41.51 A41.52 A41.53 A4.59 A41.81 A41.89 A41.9 A42.7 A54.86 B37.7 Severe Sepsis Diagnosis List (ICD- 10) 995.92 R65.20 Septic Shock Diagnosis List (ICD- 10) 785.52 R65.21

Sepsis Training Materials

Sepsis Training Materials, cont. Pocket Cards for Providers Front Back

Sepsis ICU Documentation

Sepsis ED Timing Chart

Sepsis ED Timed Worksheet

ED Flowsheet for Time Zero

Thank You for joining us for this Davies Webinar Jonathan French, Senior Director, Healthcare Information Systems jfrench@himss.org @jfrenchhimss on Twitter Arnol Simmons, Manager, Healthcare Information Systems asimmons@himss.org www.himss.org/davies @ArnolSimmonsHIM on Twitter The HIMSS Nicholas E. Davies Award of Excellence Awarding IT. Improving Healthcare.