Influence the Patient-Doctor Discussion at Point-of-Care

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At-A-Glance Influence the Patient-Doctor Discussion at Point-of-Care RemedyMD is a proven patient education program designed to engage consumers in the crucial moments surrounding treatment before, during and after conversations with their physician starting with the doctors office waiting room and beyond. Sponsored Turnkey Program Receive brand and doctor office exclusivity with this unique patient education program: ondition-specific editorial for each C publication title, sourced from leading medical journals and written by the award-winning editors of Remedy Health Media, the leader in consumer health education Single Sponsored RemedyMD argeted distribution to high-traffic T medical specialists offices Delivered in dedicated display racks Available in full or digest size format an be delivered through the following C channels: in-doctor offices, in-pharmacies, in-home, online and more Expanded exposure through: Showcase Your Commitment to Patient Education Advertisement Doctor Discussion Guide Your Angina Is angina affecting your quality of life? For some people, chronic angina takes some of the joy out of life. For others, it is a minor annoyance that doesn t keep them from living fully. Whether you feel burdened by your angina or you feel like it is under control, if you are having attacks despite treatment, angina may be affecting you more than you think. Doctor Intro Letter communication highlighting your brand Doctor Discussion Guide encourages patients to open up a dialogue with their prescribing doctor managing Use this checklist to communicate with your cardiologist about how angina is affecting your life. 1. In the past month, how many episodes of angina have you had? none We rely on a patient s description of symptoms to decide on further tests and treatment. Dr Schaefer, cardiologist 1-4 5-8 9 or more 2. Have you limited or totally given up any activities or work because of your angina? yes no If so, what?: 3. Do you ever have angina when you are: resting dressing or bathing walking at an ordinary pace walking uphill or quickly climbing stairs doing general housework/ yardwork having emotional stress being sexually active moving heavy objects in hot or cold weather eating large meals smoking cigarettes other 4. How much has angina affected your quality of life? not at all 1 2 somewhat 3 a lot 4 5 5. Do you wish more could be done to reduce your angina? Proprietary custom research Program extensions available yes no 6. Is there anything else you d like your doctor to know about your angina? Brought to you by: Your cardiologist is listening 7. What other topics do you want to discuss with your doctor? managing medication side effects treatment options diet and exercise other: Complete this checklist and share it with your cardiologist continued on back Sponsored Doctor Discussion Guide (two-sided) 4A Doctor Intro Letter

Editorial Provides Relevant Context for Your Message RemedyMD is designed to stimulate an intelligent and productive conversation with the doctor. Original content is reviewed by a Medical Advisory Board and is edited for consumers into an easy-to-read and understand format. Through this method, we help patients before, during and after their doctor visit, with relevant educational content relating directly to the issue discussed with the physician specialist. Feature Story Science-based editorial with supporting references from medical journals News Updates on current research Ask the Experts Interviews with prominent specialists in the field Diagnosis & Tests Describes how physicians arrive at a diagnosis with an overview of symptoms and exams Treatment & Solutions Focus on the innovation behind the latest treatment options, including medications, devices and new tests Fact vs. Myths Deciphers the truth from accepted health rumors Healthy Living A practical section that helps patients manage diet and exercise dditional Resources A More information to promote condition-specific health awareness and understanding Developed by the editors of Johns Hopkins Medicine White Papers and UC Berkeley Wellness Reports

Editorial 2013 Editorial Calendar Sleep Disorders Every Issue Condition Overview Ask the Experts News Diagnosis & Tests Treatments & Solutions Healthy Living Myth vs. Facts Additional Resources Bonus DOCTOR DISCUSSION GUIDE! See page 10A Inside 2 Risk Factors 4 Symptoms & Diagnosis 6 Treatment Options 8 Monitoring Success 10 Ask the Doctor 12 Healthy Choices 14 Lifestyle Changes Breast Cancer Prevention Find Interactive Tools at HealthCentral.com/sleep The concepts proposed in this document are property of Remedy Health Media LLC. All rights reserved, 2012. Bonus DOCTOR DISCUSSION GUIDE! See page 10A COPD 2 Understanding Breast Cancer 4 Talk to your doctor 6 Risks & Risk Factors 8 Screenings & Tests 10 Self Exams 12 Eat Right & Be Active! 14 Cool Tools, Tips & Apps Bonus DOCTOR DISCUSSION GUIDE! Find Interactive Tools at BreastCancer.org The concepts proposed in this document are property of Remedy Health Media LLC. All rights reserved, 2011. See page 10A Win $600! Angina Details on page 3. 2 Risk Factors 4 Symptoms & Diagnosis 6 Treatment Options 8 Monitoring Success 10 Ask the Doctor 12 Healthy Choices 14 Lifestyle Changes Your Free Doctor Discussion GuiDe! see page 4A What s Inside 2 4A 6 8 10 14 16 Chronic Migraine: History of the disease and its prevalence among women Inside The concepts proposed in this document are property of Remedy Health Media LLC. All rights reserved, 2012 ANGINA_COVER-4B.indd 1 sthma: Touching upon the different asthma triggers A and treatments Summer Sleep Disorders: Insomnia and Sleep Apnea the most common sleep stealers What s Inside REMEDYMD Issue Topics Spring COPD: Focusing on two distinct diseases that obstruct airflow Emphysema and Chronic Bronchitis Understand Angina Talk to Your Doctor Ask Our Experts Diagnosis & Best Tests Life Without Pain Eat Right & Be Active! Cool Tools, Tips & Apps Fall Breast Cancer: Highlighting preventative care and new, innovative treatments veractive Bladder: Get to know your symptoms and identify simple O management techniques Winter Rheumatoid Arthritis: Coping mechanisms for dealing with severe joint pain and stiffness Heart Health: From Angina to Hypertension and everything in between 4/23/12 2:56 PM Closing Dates & Specialty Offices Spring Issues Close Date DDG Materials Due Ad Material Due In Office COPD - Pulmonology Offices... 11/26/12... 12/17/12... 1/10/13... 3/10/13 Asthma - Allergists & Immunology Offices... 12/26/12... 1/18/13... 2/15/13... 4/10/13 Summer Issues Sleep Disorders - PCP Offices... 2/26/13... 3/18/13... 4/15/13... 6/10/13 Chronic Migraine - Neurology Offices... 3/26/13... 4/16/13... 5/14/13... 7/10/13 Fall Issues Breast Cancer - Oncology Offices... 6/27/13... 7/18/13... 8/15/13... 10/10/13 Overactive Bladder - Urology Offices... 7/27/13... 8/17/13... 9/14/13... 11/10/13 Winter Issues Rheumatoid Arthritis - Rheumatology Offices... 9/25/13... 10/16/13... 11/13/13... 1/10/14 Heart Health - Cardiology Offices... 10/26/13... 11/16/13... 12/14/13... 2/10/14 * Dates and issue topics subject to change. Closing date extensions available upon request

Research Connect With the Best Prospects Self-selected in the waiting room and driven by the prospect of improved health, RemedyMD TM readers actively look for health information relevant to their specific needs searching for the tools that allow them to assess their condition and evaluate treatment options with their doctors. The Value of Doctor Office Distribution Patients today spend an average of 22 minutes in a specialists waiting room. Take advantage of that time and prep patients for an engaging experience with their doctor.* RemedyMD Reinforces Your Brand Message During This Crucial Time 68% research healthcare information to be better informed about different treatment options (Index 144) 62% value magazines in doctors offices (Index 203) RemedyMD Stimulates Patient-Doctor Conversation 59% often discuss new prescription medications with their doctor (Index 172) 51% are willing to ask their doctor for a prescription medication drug sample that they ve seen advertised (Index 131) RemedyMD Drives Brand Preference 55% normally use drug brands recommended by their doctor (Index 119) 37% feel it s worth paying more for branded prescription medication rather than generic (Index 210) Actions Taken Due to Healthcare Advertising Aiding Professional Discussions Index Discussed ad with a doctor 153 Asked doctor for a product sample 290 Asked doctor to prescribe a specific drug 245 Consulted a pharmacist 155 Aiding In-Home Actions Returned a free sample card 284 Returned a card to request more information 373 Referred to a book, journal or magazine for more info 313 Called a toll free number to get additional information 360 Discussed ad with a friend/relative 274 Visited a website 140 Aiding in Compliance/ Adherence Switched to a different brand 251 Called for a prescription refill 182 Remembered to take medication 149 Sources: MARS 10/11 Doublebase; * Press Ganey 2010 Medical Practice Pulse Report Patient Perspectives on American Health Care (Represents the experiences of 2,701,020 patients treated at 11,876 sites nationwide between January 1 and December 31, 2009) Aiding In-Store Action Purchased a non-prescription product 136 Used a coupon 170 Source: MARS 10/11 Doublebase

Specs 2013 Material Specifications General Specifications: Full Size Trim: 7-7/8 x 10-1/2 Copy and layout should be designed so that ad can be positioned on either a right or left-hand page. Bleed: 8-1/8 x 10-3/4 Allow 1/8 bleed on all sides. Safety: 7-3/8 x 10 Hold live matter 1/4 from pub trim size on each side. (keep registration marks outside trim dimension) Spread: Submit two (2) single pages. Keep registration marks outside trim dimensions. Binding Method: Saddle-stitched on 10-1/2 side. Digest Size Trim: 5-1/4 x 7-5/16 Copy and layout should be designed so that ad can be positioned on either a right or left-hand page. Bleed: 5-1/2 x 7-9/16 Allow 1/8 bleed on all sides. Safety: 4-3/4 x 6-13/16 Hold live matter 1/4 from pub trim size on each side. (keep registration marks outside trim dimension) Spread: Submit two (2) single pages. Keep registration marks outside trim dimensions. Binding Method: Saddle-stitched on 7-5/16 side. Digital Ad Specifications: PDF/X1a format is the preferred file format for file submission PDF/X1a file saved with only one ad per file All high-resolution images and fonts must be embedded Images must be CMYK or Grayscale and at least 200 dpi Total area density should not exceed 280% TAC Standard trim and bleed marks, offset 1/8 outside trim (No marks included in the live or bleed image area) CMYK process only. No RGB or Spot (Pantone) colors Flatten all transparency Contact Information: Estelle Selzer Production Manager 500 Fifth Avenue, 19th Floor New York, NY 10110 Phone: 212.994.9336 E-mail: estelle@remedyhealthmedia.com Fax: 917.351.1432 FTP File Posting Instructions: FTP site: ftp://ftp.mediftp.com Username: medizine@mediftp.com Password: 198Zt52 (case sensitive) 1. Open a browser window 2. In the address bar type ftp.mediftp.com and hit enter. You will be told you do not have access. Click OK, then click on File -Login as... Enter the user name and password above and click Log On. Double click the files folder and you can start copying. 3. Once file has been successfully posted, please send an e-mail/call with the filename: Estelle Selzer E-mail: estelle@remedyhealthmedia.com Phone: 212.994.9336 NOTE: Color proof is required. Publisher will charge for any cost incurred in preparing material submitted by advertiser that does not meet mechanical requirements. Color Proof Guidelines: Digital, Press, or Off-press proofs which meet SWOP C5 (Coated #5) specifications

Project Timing Details & Timing Timing 15 weeks prior to in-office Contract Signed Week 1 Kick off Conference Call Doctor Discussion Guide/ Doctor Intro Letter: Custom Research: Week 3 Client supplied content: Client s decision to utilize research DDG questions and assets Week 4 DDG layout to Client for legal review Week 5 Client supplied questions due Week 6 Client legal feedback on DDG Week 7 Doctor Discussion Guide to printer Client sign off on survey Doctor Intro Letter to printer Week 7 Ad Materials Due/We print BRCs/Supplied BRCs Due Week 8-14 Production (Printing/Mailing of Issues) Week 15 In Office Survey Goes Live ** * Timeline may change depending on client s legal review process ** Survey closes approximately 3 months after in office date